Hiroki Nariai, MD, PhD, MS

Hiroki Nariai, MD, PhD, MS

Pediatric Neurology
Primary Location
Calabasas Pediatrics
26585 Agoura Road
Suite 360
Calabasas, California 91302
Phone
Fax
818-880-8014

About

Dr. Nariai is currently an Assistant Professor of Pediatrics in the Division of Pediatric Neurology at UCLA. He specializes in pediatric epilepsy, with a specific focus on drug-resistant epilepsy and epilepsy surgery evaluation. Dr. Nariai is board-certified in pediatric neurology, epilepsy, and clinical neurophysiology.

Dr. Nariai is actively involved in the UCLA Pediatric Epilepsy Surgery Program and the UCLA Infantile Spasms Program from both a clinical and research perspective. His research has been funded by UCLA Children's Discovery and Innovation Institute (CDI), the American Academy of Neurology, the American Epilepsy Society, the American Brain Foundation, and the Epilepsy Foundation. Through his ongoing work, he is studying EEG (electroencephalogram) biomarkers of drug-resistance in epilepsy, and human brain mapping utilizing computational EEG analysis.

Dr. Nariai is an active member of the American Academy of Neurology (AAN) and the American Epilepsy Society (AES).

Education

Medical Board Certifications

Epilepsy, American Board of Psychiatry and Neurology, 2018
Clinical Neurophysiology, American Board of Psychiatry and Neurology, 2017
Neurology with Special Qualification in Child Neurology, American Board of Psychiatry and Neurology, 2016

Fellowships

UCLA School of Medicine, 2018
UCLA School of Medicine, 2017
Wayne State University School of Medicine, 2011

Residencies

Albert Einstein College of Medicine/Yeshiva University, 2016
Albert Einstein College of Medicine/Yeshiva University, 2013

Internship

Aso Iizuka Hospital/Keio University School of Medicine, 2009

Degrees

UCLA Fielding School of Public Health, MS, 2020
Keio University School of Medicine, PhD, 2019
Keio University School of Medicine, MD, 2005

Locations

Hospital Affiliations

Research

Interests

  • Epilepsy surgery
  • Computational EEG analysis
  • Brain mapping
  • Infantile spasms

Publications

Selected publications relevant to Dr. Nariai's specialty:

  1. Nariai H, Nagasawa T, Juhász C, Sood S, Chugani HT, and Asano E. “Statistical mapping of ictal high-frequency oscillations in epileptic spasms.” Epilepsia. 2011 Jan;52(1):63-74. PMID: 21087245.
  2. Nariai H, Matsuzaki N, Juhász C, Nagasawa T, Sood S, Chugani HT, and Asano E. “Ictal high-frequency oscillations at 80-200Hz coupled with delta phase in epileptic spasms.” Epilepsia. 2011 Oct;52(10):e130-4. PMID:21972918.
  3. Nariai H, Beal J, Galanopoulou AS, Mowrey WB, Bickel S, Sogawa Y, Jehle R, Shinnar S, and Moshé SL. " Scalp EEG Ictal gamma and beta activity during infantile spasms: Evidence of focality." Epilepsia. 2017;58(5):882-892. PMID: 28397999
  4. Bernardo D, Nariai H, Hussain S, Sankar R, Salamon N, Krugger D, Sahin M, Northup H, Bebin EM, Wu JY; UCLA Pediatric Epilepsy Group; TACERN Study Group. " Visual and semi-automatic non-invasive detection of interictal fast ripples: A potential biomarker of epilepsy in children with tuberous sclerosis complex." Clinical Neurophysiology. 2018 Jul;129(7):1458-1466. PMID: 29673547
  5. Nariai H, Bernardo D, Sankar R, Fallah A, Wu JY and Hussain S. "Inter-rater reliability in visual identification of high frequency oscillations on electrocorticography and scalp EEG." Epilepsia Open. 2018;3:127-132. PMID: 30564771
  6. Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman R, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, and Wu JY. “Prospective Cohort Study: Fast Ripple Localization Delineates the Epileptogenic Zone.” Clinical Neurophysiology. 2019 Nov;130(11):2144-2152. PMID: 31569042
  7. Cepeda C, Levinson S, Nariai H, Yazon VW, Tran C, Barry J, Oikonomou K, Vinters HV, Fallah A, Mathern GW, Levine MS, and Wu JY. “Pathological High-Frequency Oscillations Associate with Increased Spontaneous GABA Synaptic Activity in Pediatric Epilepsy” Neurobiol Dis. 2020 Feb;134:104618. PMID: 31629890
  8. Okubo Y, Fallah A, Hayakawa I, Handa A, and Nariai H. “Trends in hospitalization and readmission for pediatric epilepsy and underutilization of epilepsy surgery in the United States.” Seizure. 2020 May 17:S1059-1311(20)30142-4. PMID: 32471799
  9. Nariai H, Hussain SA, Bernardo D, Motoi H, Sonoda M, Kuroda N, Asano E, Nguyen J, Elashoff D, Sankar R, Bragin A, Staba RJ, Wu JY. Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms. Clin Neurophysiol. 2020 Sep 3;131(11):2527-2536. PMID: 32927206
  10. Kuroda N, Sonoda M, Miyakoshi M, Nariai H, Jeong JW, Motoi H, Luat AG, Sood S, and Asano E. "High-frequency oscillation and phase-amplitude coupling comparably improve the prediction of epilepsy surgery outcome." Brain Commun. 2021 Mar 14;3(2):fcab042. PMID: 33959709

Link to Dr. Naria's publications >

Awards

  • The Elsie and Isaac Fogelman Endowed Term Chair in Pediatric Neurology, David Geffen School of Medicine (2020-2025)
  • UCLA Children's Discovery and Innovation Institute (CDI) Today's and Tomorrow's Children's Fund (TTCF) Bridge Grant (2021-2022)
  • UCLA Children's Discovery and Innovation Institute (CDI) Seed Grant (2021)
  • Susan Spencer, MD Clinical Research Training Scholarship in Epilepsy (2018-2020)
  • Epilepsy Foundation Care and Cure Fellowship (2016-2018)
  • American Epilepsy Society Fellows Program (Travel Grant) (2020)
  • The Isabelle Rapin M.D. Scholarly Activity Award, Albert Einstein College of Medicine (2016)
  • Recognition of "Teaching Star for Medical Students", Albert Einstein College of Medicine (2016)
  • Young Investigator Award (Travel Grant), Neurobiology of Disease in Children/Child Neurology Society (2013, 2015)
  • Recognition of Outstanding Research Performed during Fellowship Training at Children’s Hospital of Michigan (2010, 2011)
  • Awarded as “The Doctor of Distinction” at Aso Iizuka Hospital, Japan (2006)