Hiroki Nariai, MD, PhD, MS
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Hiroki Nariai, MD, PhD, MS

  • Pediatric Neurology
Pediatrics in Calabasas | 26585 Agoura Road, Suite 360, Calabasas, CA 91302

About

Dr. Nariai is currently an Assistant Professor of Pediatrics in the Division of Pediatric Neurology at UCLA. He specializes in pediatric epilepsy, specifically focusing on drug-resistant epilepsy and epilepsy surgery evaluation. He currently serves as the Medical Director of the Pediatric Epilepsy Surgery Program at UCLA. Dr. Nariai is board-certified in pediatric neurology, epilepsy, and clinical neurophysiology.

Dr. Nariai is actively involved in the UCLA Pediatric Epilepsy Surgery Program and the UCLA Infantile Spasms Program from both a clinical and research perspective. His research has been funded by the National Institute of Health (NIH), the UCLA Children's Discovery and Innovation Institute (CDI), the American Academy of Neurology, the American Epilepsy Society, the American Brain Foundation, and the Epilepsy Foundation.

In his ongoing research, Dr. Nariai is exploring EEG (electroencephalogram) biomarkers of epilepsy and conducting computational EEG analyses during epilepsy surgery. He aims to pinpoint the brain regions responsible for seizure generation and identify functional brain areas, to minimize complications associated with epilepsy surgery.

Dr. Nariai is an active member of the American Academy of Neurology (AAN) and the American Epilepsy Society (AES).

Languages

English, Japanese

Education

Medical Board Certifications

Epilepsy, American Board of Psychiatry and Neurology, 2018
Clinical Neurophysiology, American Board of Psychiatry and Neurology, 2017
Neurology with Special Qualification in Child Neurology, American Board of Psychiatry and Neurology, 2016

Fellowships

Pediatric Epilepsy, UCLA School of Medicine, 2018
Clinical Neurophysiology, UCLA School of Medicine, 2017
Clinical Neurophysiology, Wayne State University School of Medicine, 2011

Residencies

Pediatric Neurology, Albert Einstein College of Medicine/Yeshiva University, 2016
Pediatrics, Albert Einstein College of Medicine/Yeshiva University, 2013

Internship

Pediatrics, Aso Iizuka Hospital/Keio University School of Medicine, 2009

Degrees

MS, UCLA Fielding School of Public Health, 2020
PhD, Keio University School of Medicine, 2019
MD, Keio University School of Medicine, 2005

Recognitions

  • The Mentored Patient-Oriented Research Career Development Award (NIH/NINDS K23), 2023-2028
  • The Elsie and Isaac Fogelman Endowed Term Chair in Pediatric Neurology, David Geffen School of Medicine, 2020-2025
  • UCLA Children's Discovery and Innovation Institute (CDI) Today's and Tomorrow's Children's Fund (TTCF) Bridge Grant, 2021-2022
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Locations

San Fernando Valley

Pediatrics in Calabasas

Pediatrics| Pediatric Endocrinology| Pediatric Gastroenterology +5 more specialties

Hospital Affiliations

Research

Interests

  • Epilepsy surgery
  • Computational EEG analysis
  • Brain mapping
  • Infantile spasms

Publications

Selected publications relevant to Dr. Nariai's specialty:

  1. Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman R, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, and Wu JY. “Prospective Cohort Study: Fast Ripple Localization Delineates the Epileptogenic Zone.” Clinical Neurophysiology. 2019 Nov;130(11):2144-2152. PMID: 31569042
  2. Cepeda C, Levinson S, Nariai H, Yazon VW, Tran C, Barry J, Oikonomou K, Vinters HV, Fallah A, Mathern GW, Levine MS, and Wu JY. “Pathological High-Frequency Oscillations Associate with Increased Spontaneous GABA Synaptic Activity in Pediatric Epilepsy” Neurobiol Dis. 2020 Feb;134:104618. PMID: 31629890
  3. Okubo Y, Fallah A, Hayakawa I, Handa A, and Nariai H. “Trends in hospitalization and readmission for pediatric epilepsy and underutilization of epilepsy surgery in the United States.” Seizure. 2020 May 17:S1059-1311(20)30142-4. PMID: 32471799
  4. Nariai H, Hussain SA, Bernardo D, Motoi H, Sonoda M, Kuroda N, Asano E, Nguyen J, Elashoff D, Sankar R, Bragin A, Staba RJ, Wu JY. Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms. Clin Neurophysiol. 2020 Sep 3;131(11):2527-2536. PMID: 32927206
  5. Kuroda N, Sonoda M, Miyakoshi M, Nariai H, Jeong JW, Motoi H, Luat AG, Sood S, and Asano E. "High-frequency oscillation and phase-amplitude coupling comparably improve the prediction of epilepsy surgery outcome." Brain Commun. 2021 Mar 14;3(2):fcab042. PMID: 33959709
  6. Nagahama Y, Zervos T, Murata K, Holman L, Karsonovich T, Parker JJ, Chen JS, Phillips W, Fajardo M, Nariai H, Hussain S, Porter B, Grant GA, Ragheb J, Wang S, O’Neill BR, Alexander A, Bollo RJ, Fallah A. “Real-world preliminary experience with responsive neurostimulation in pediatric epilepsy: a multi-center retrospective observational study” Neurosurgery. 2021 Nov 18;89(6):997-1004. PMID: 34528103
  7. Miyakoshi M, Nariai H, Rajaraman RR, Bernardo D, Shrey DW, Lopour B, Sim MS, Staba RJ, and Hussain SA. “An automated pipeline for preprocessing scalp-recorded awake EEG data for phase-amplitude coupling analysis: application to infantile spasms.” Epilepsy Res. 2021 Dec;178:106809. doi: 10.1016/j.eplepsyres.2021.106809. Epub 2021 Nov 7. PMID: 34823159
  8. Zhang Y, Lu Q, Monsoor T, Hussain SA, Qiao JX, Salamon N, Fallah A, Sim MS, Asano E, Sankar R, Staba RJ, Engel J, Speier W, Roychowdhury V, and Nariai H. “Refining epileptogenic high-frequency oscillations using deep learning: a reverse engineering approach.” Brain Commun. 2021 Nov 3;4(1):fcab267. eCollection 2022. PMID: 35169696
  9. Mazumder R, Lagoro DK, Nariai H, Danieli A, Eliashiv D, Engel J Jr, Dalla Bernardina B, Kegele J, Lerche H, Sejvar J, Matuja W, Schmutzhard E, Bonanni P, De Polo G, Wagner T, Winkler AS. “Ictal Electroencephalographic Characteristics of Nodding Syndrome: A Comparative Case-Series from South Sudan, Tanzania, and Uganda” Ann Neurol. 2022 Apr 19. doi: 10.1002/ana.26377. PMID: 3543820
  10. Zhang Y, Chung H, Ngo JP, Monsoor T, Hussain SA, Matsumoto JH, Walshaw PD, Fallah A, Sim MS, Asano E, Sankar R, Staba RJ, Engel J, Speier W, Roychowdhury V and Nariai H. "Characterizing physiological high-frequency oscillations using deep learning" J Neural Eng. 2022. PMID: 36541546

Link to Dr. Naria's publications

Recognitions

  • The Mentored Patient-Oriented Research Career Development Award (NIH/NINDS K23), 2023-2028
  • The Elsie and Isaac Fogelman Endowed Term Chair in Pediatric Neurology, David Geffen School of Medicine, 2020-2025
  • UCLA Children's Discovery and Innovation Institute (CDI) Today's and Tomorrow's Children's Fund (TTCF) Bridge Grant, 2021-2022
  • UCLA Children's Discovery and Innovation Institute (CDI) Seed Grant, 2021
  • American Epilepsy Society Fellows Program (Travel Grant), 2020
  • Susan Spencer, MD Clinical Research Training Scholarship in Epilepsy, 2018-2020
  • Epilepsy Foundation Care and Cure Fellowship, 2016-2018
  • The Isabelle Rapin M.D. Scholarly Activity Award, Albert Einstein College of Medicine, 2016
  • Recognition of "Teaching Star for Medical Students", Albert Einstein College of Medicine, 2016
  • Young Investigator Award (Travel Grant), Neurobiology of Disease in Children/Child Neurology Society, 2013, 2015
  • Recognition of Outstanding Research Performed during Fellowship Training at Children’s Hospital of Michigan, 2010, 2011
  • Awarded as “The Doctor of Distinction” at Aso Iizuka Hospital, Japan, 2006