James S. Lee, MD

James S. Lee, MD

Interventional Cardiology
Average rating: 5.0
(482 ratings)  
Accepting new patients
Primary Location
Santa Clarita Primary & Specialty Care
25775 McBean Parkway
Suite 202
Valencia, California 91355


Dr. James Lee is originally from New York where he attended Cornell University and earned a bachelor's of science in applied economics, business management, and marketing. He then earned a medical degree from Loma Linda University followed by an internship and residency in Internal Medicine at the Cleveland Clinic Foundation. He then pursued a fellowship in Cardiovascular Medicine at the UCLA San Fernando Valley Program where he served as the Chief Cardiology Fellow for the VA Greater LA Healthcare System and Olive View Medical Center. He also completed an Interventional Cardiology Fellowship at the Mount Sinai Hospital in New York.

Dr. Lee is an Associate Clinical Professor of Medicine at UCLA and the Associate Regional Director and Co-Lead for the Quality and Teaching Committee of Interventional Cardiology at UCLA. He serves on the UCLA Department of Medicine Quality Committee as a Peer Physician Coach. He also is the Medical Director of the Cardiology Division, Cardiac Cath Lab, STEMI program, and Cardiac Rehab Program at Henry Mayo Newhall Hospital.

Dr. Lee is certified by the National Board of Medical Examiners, the American Board of Internal Medicine, the Subspecialty Board of Cardiovascular Disease and Interventional Cardiology. He is a Fellow of the American College of Cardiology and of the Society of Cardiovascular Angiography and Interventions. 

Dr. Lee specializes in the management of coronary artery disease through complex coronary interventions and lifestyle modification. He also has special interests in diet and weight loss optimization. He is committed to excellence in comprehensive health care through understanding patient's health care needs and goals with implementation of state-of-the-art techniques and compassionate care.




Medical Board Certifications

Interventional Cardiology, American Board of Internal Medicine, 2009
Cardiovascular Disease, American Board of Internal Medicine, 2008
Internal Medicine, American Board of Internal Medicine, 2005


Interventional Cardiology, Icahn School of Medicine at Mount Sinai, 2009
Cardiovascular Disease, VA Greater Los Angeles Healthcare System, 2008


Internal Medicine, Cleveland Clinic Foundation, 2005


Internal Medicine, Cleveland Clinic Foundation, 2003


MD, Loma Linda University School of Medicine, 2002


Hospital Affiliations

Ronald Reagan UCLA Medical Center

UCLA Santa Monica Medical Center


  • Super Doctors® Southern California, 2023
  • Santa Carita Elite Magazine Ultimate Cardiologist, 2023
  • Super Doctors® Southern California, 2017-2022
  • Super Doctors® Southern California Rising Stars, 2013-2015
  • Castle Connolly Regional Top Doctors
  • Mount Sinai Hospital Interventional Cardiology Fellow of the Year, 2009
  • MacKenzie Foundation Medical Scholarship, 2002
  • Walter E. Macpherson Society Research Scholarship and Scientific Research Award, 2000