Ming-Sing Si, MD
Accepting new patients

Ming-Sing Si, MD

  • Cardiac Surgery
Children's Heart Center | 200 Medical Plaza, Suite 330, Los Angeles, CA 90095


Dr. Si is an academic congenital cardiac surgeon with clinical interests in the surgical treatment of neonatal, pediatric, and adult congenital heart disease. Dr. Si's clinical research is in single ventricle heart disease and heart failure in the setting of congenital heart disease. He also has clinical interests in heart valve repair in the setting of congenital heart disease. His laboratory research investigation is focused on delineating the pathophysiology of heart failure and cardiac fibrosis as well as the development of novel therapies for these entities. Specifically, the Si Lab is investigating the developmental and postnatal functional roles of the SLIT-ROBO signaling axis in the cardiovascular system by utilizing diverse in vitro and in vivo experimental approaches. His research team is motivated to make impactful scientific discoveries and to advance the treatment of heart failure.

Dr. Si also performs surgeries at Children's Hospital of Orange County for those who live in the Orange County area. 




Medical Board Certifications

Congenital Cardiac Surgery, American Board of Thoracic Surgery, 2013
Thoracic and Cardiac Surgery, American Board of Thoracic Surgery, 2010


Cardiac Surgery, University of Michigan Health System, 2009
Thoracic Surgery, University of Michigan Health System, 2008
General Surgery, UC San Francisco School of Medicine, 2006
General Surgery, UC Irvine School of Medicine, 2002


MD, UCLA School of Medicine, 1999


Hospital Affiliations



  • Congenital heart disease
  • Heart failure
  • Heart transplantation
  • Single ventrical heart disease
  • Aortic valve repair
  • Cardiac fibrosis
  • Cardiac hypertrophy


  • Aetna
  • Anthem Blue Cross
  • Blue Shield of California
  • Centivo
  • Cigna
  • First Health
  • Health Net of California
  • Interplan (part of HealthSmart)
  • L.A. Care
  • MultiPlan
  • UFCM Health System
  • Prime Health Services
  • Private Healthcare Systems (PHCS)
  • UnitedHealthcare

The list of health care plans above may not be comprehensive and could change. 
Please contact your benefits coordinator or health insurance company directly to verify coverage.

Visit our health insurance information page for more details.


  • Super Doctors® Southern California, 2024
  • Castle Connolly Top Doctor, 2021, 2022
  • Hour Detroit Magazine's Top Doctor, 2021