Olcay Aksoy, MD

Olcay Aksoy, MD

Interventional Cardiology
Primary Location
Cardiovascular Center
100 Medical Plaza
630 West
Los Angeles, California 90095
Phone
Fax
310-825-9014

About

After completing his studies at Duke University School of Medicine, Dr. Aksoy went onto complete his Internal Medicine residency at Johns Hopkins University Hospitals and Cardiovascular Medicine and Interventional Cardiology fellowships at the Cleveland Clinic Foundation. He then joined UCLA Division of Cardiology in 2013 and has been a faculty member since.

Dr. Aksoy’s focus since his arrival has been prevention and treatment of cardiovascular diseases. As an active clinician, Dr. Aksoy specializes in evaluating and treating patients with coronary artery and structural heart diseases. He is involved in invasive evaluation and treatment of cardiovascular diseases where he performs coronary angiograms/angioplasty and stenting, minimally invasive treatment of heart valve diseases (TAVR and Mitraclip), as well as atrial septal defect/patent foramen ovale therapies. Dr. Aksoy is currently the Associate Director of Aortic Valve Therapies.

Dr. Aksoy is also an active member of our research program and is serving as the Associate Director of Clinical Research in Interventional Cardiology. He directs and leads several research trials, including those of structural and interventional therapies. He is also working on developing newer generation technologies/devices for the treatment of cardiovascular diseases.

Education

Medical Board Certifications

Interventional Cardiology, American Board of Internal Medicine, 2012
Cardiovascular Disease, American Board of Internal Medicine, 2011
Internal Medicine, American Board of Internal Medicine, 2008

Fellowships

Cleveland Clinic Foundation, 2013
Cleveland Clinic Foundation, 2011

Residency

Johns Hopkins Hospital, 2008

Internship

Johns Hopkins Hospital, 2006

Degree

Duke University School of Medicine, MD, 2005

Hospital Affiliations

Ronald Reagan UCLA Medical Center

UCLA Santa Monica Medical Center

Areas of Focus

Aortic valve sclerosis
Abnormal coronary angiography
Aortic stenosis
Abnormal stress test
Aortic regurgitation
Aortic valve disease

Videos

Aortic Stenosis: The Future is Now!

Research

Interests

Dr. Aksoy is also an active member of our research program and is serving as the Associate Director of Clinical Research in Interventional Cardiology. He directs and leads several research trials, including those of structural and interventional therapies. He is also working on developing newer generation technologies/devices for the treatment of cardiovascular diseases.

Publications

  • Fanous EJ, Mukku RB, Dave P, Aksoy O, Yang EH, Benharash P, Press MC, Rabbani AB, Aboulhosn JA, Rafique AM. Paravalvular Leak Assessment: Challenges in Assessing Severity and Interventional Approaches. Curr Cardiol Rep. 2020 Oct 10;22(12):166. doi: 10.1007/s11886-020-01418-7. 

  • Bae DJ, Tehrani DM, Rabadia SV, Frost M, Parikh RV, Calfon-Press M, Aksoy O, Umar S, Ardehali R, Rabbani A, Bokhoor P, Nsair A, Currier J, Tobis J, Fonarow GC, Dave R, Rafique AM. Angiotensin Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use Among Outpatients Diagnosed With COVID-19. Am J Cardiol. 2020 Oct 1;132:150-157. doi: 10.1016/j.amjcard.2020.07.007. Epub 2020 Jul 12. 

  • Small AJ, Aksoy O, Levi DS, Salem MM, Yang EH, Aboulhosn JA. Combined Transcatheter Tricuspid and Pulmonary Valve Replacement. World J Pediatr Congenit Heart Surg. 2020;11(4):432-437. doi:10.1177/2150135120918777 

  • Tan, W., Parikh, R. V., Chester, R., Harrell, J., Franco, V., Aksoy, O., Dave, R., Rafique, A., & Press, M. (2020). Single Center Trends in Acute Coronary Syndrome Volume and Outcomes During the COVID-19 Pandemic. Cardiology research, 11(4), 256–259.  

  • Xu MX, Teng RL, Ruddy TD, Schoenhagen P, Bartel T, Di Bartolomeo R, Aksoy O, Desai M, von Kodolitsch Y, Escaned J, McCullough PA, Vasudevan A, Shen CX, Zhao X, Zhou YF, Xu HF, Cheng XJ, He YM; written on behalf of the AME Interventional Cardiology Collaborative Group. The CatLet score: a new coronary angiographic scoring tool accommodating the variable coronary anatomy for the first time. J Thorac Dis. 2019 Dec;11(12):5199-5209. 

  • Eyvazian DVA, Gordin JS, Yang EH, Aksoy O, Honda HM, Busuttil RW, Agopian VG, Vorobiof G. Incidence, Predictors, and Outcomes of New Onset Left Ventricular Systolic Dysfunction after Orthotopic Liver Transplantation. J Card Fail. 2019 Mar;25(3):166-172. doi: 10.1016/j.cardfail.2018.10.013. Epub 2018 Nov 6. 

  • Toppen W, Suh W, Aksoy O, Benharash P, Bowles C, Shemin RJ, Kwon M. Vascular Complications in the Sapien 3 Era: Continued Role of Transapical Approach to Transcatheter Aortic Valve Replacement. Semin Thorac Cardiovasc Surg. 2018 Summer;30(2):144-149. doi: 10.1053/j.semtcvs.2018.02.032. Epub 2018 Mar 6. 

  • Asthana N, Mantha A, Yang EH, Suh W, Aksoy   O, Shemin RJ, Vorobiof G, Benharash P. Myocardial functional changes in transfemoral versus transapical aortic valve replacement. J Surg Res. 2018 Jan;221:304-310. doi: 10.1016/j.jss.2017.08.036. Epub 2017 Oct 7. 

  • Nguyen KL, Moriarty JM, Plotnik AN, Aksoy O, Yoshida T, Shemin RJ, Suh WM, Finn JP. Ferumoxytol-enhanced MR Angiography for Vascular Access Mapping before Transcatheter Aortic Valve Replacement in Patients with Renal Impairment: A Step Toward Patient-specific Care. Radiology. 2018 Jan;286(1):326-337. doi: 10.1148/radiol.2017162899. Epub 2017 Oct 16 

  • Garg V, Tan W, Ardehali R, Shah J, Huynh T, Aksoy O. Giant cell myocarditis masquerading as orbital myositis with a rapid, fulminant course necessitating mechanical support and heart transplantation. ESC Heart Fail. 2017 Aug;4(3):371-375. doi: 10.1002/ehf2.12141. Epub 2017 Mar 8. 

  • Packard RRS, Luo Y, Abiri P, Jen N, Aksoy O, Suh WM, Tai YC, Hsiai TK. 3-D Electrochemical Impedance Spectroscopy Mapping of Arteries to Detect Metabolically Active but Angiographically Invisible Atherosclerotic Lesions. Theranostics. 2017 Jun 22;7(9):2431-2442. doi: 10.7150/thno.19184. eCollection 2017 

  • Toppen W, Johansen D, Sareh S, Fernandez J, Satou N, Patel KD, Kwon M, Suh W, Aksoy O, Shemin RJ, Benharash P. “Improved costs and outcomes with conscious sedation vs general anesthesia in TAVR patients: Time to wake up?” PLoS One. 2017 Apr 5;12(4):e0173777. 

  • Aksoy O, Paixao AR, Marmagkiolis K, Mego D, Rollefson WA, Cilingiroglu M. “Aortic annular rupture during TAVR: Mini review”. Cardiovasc Revasc Med. 2016 Apr-May;17(3):199-201. 

  • Aksan G, Nar G, Inci S, Yanik A, Kilickesmez KO, Aksoy O, Soylu K. “Exercise-Induced Repolarization Changes in Patients with Isolated Myocardial Bridging”. Med Sci Monit. 2015 Jul 22;21:2116-24. 

  • Xia VW, Worapot A, Huang S, Dhillon A, Gudzenko V, Backon A, Agopian VG, Aksoy O, Vorobiof G, Busuttil RW, Steadman TH. “Postoperative Atrial Fibrillation in Liver Transplantation”. American Journal of Transplantation, 2015; 15: 687-694 

  • Goel SS, Aksoy O, Gupta S, Houghtaling PL, Tuzcu EM, Marwick T, Mihaljevic T, Svensson L, Blackstone EH, Griffin BP, Stewart WJ, Barzilai B, Menon V, Kapadia SR. “Renin-Angiotensin System Blockade Therapy After Surgical Aortic Valve Replacement for Severe Aortic Stenosis: A Cohort Study”. Ann Intern Med. 2014 Nov 18;161(10):699-710. 

  • Garg A, Parashar A, Agarwal S, Aksoy O, Hammadah M, Lal Poddar K, Puri R, Svensson LG, Krishnaswamy A, Tuzcu EM, Kapadia SR. Comparison of acute elastic recoil between the SAPIEN-XT and SAPIEN valves in transfemoral-transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2014 Nov 4. 

  • Aksan G, Nar G, Inci S, Yanik A, Aksoy O, Zengin H, Meric M, Soylu K. "Exercise Induced Repolarization Changes in Patients With Isolated Myocardial Bridging", in submission. 

  • Milin AC, Vorobiof G, Aksoy O, Ardehali R. “Insights into aortic sclerosis and its relationship with coronary artery disease” J Am Heart Assoc. 2014 Sep 5; 3(5). 

  • Yousefzai R, Bajaj N, Krishnaswamy A, Goel SS, Agarwal S, Aksoy O, Aggarwal B, Duarte VE, Anabtawi A, Parashar A, Sodhi N, Thomas J, Griffin BP, Tuzcu EM, Kapadia SR. “Outcomes of Patients With Ischemic Mitral Regurgitation Undergoing Percutaneous Coronary Intervention” Am J Cardiol. 2014 Jul 18 Epub Ahead of Print 

  • Aksan G, Soylu K, Aksoy O, Ozdemir M, Yanik A, Yuksel S, Gedikli O, Gulel O, Sahin M. “The relationship between neutrophil gelatinase-associated lipocalin levels and the slow coronary flow phenomenon.” Coron Artery Dis. 2014 May 5 

  • Aksan G, Soylu K, Demircan S, Aksoy O, Yank A, Gedikli O, Yüksel S, Sahin M, Ylmaz O. “Oral anticoagulant therapy and clinical outcomes in patients with atrial fibrillation: a pilot study from a single center registry”. Blood Coagul Fibrinolysis. 2014 Apr 9. 

  • Aksoy O, Cam A, Agarwal S, Ige M, Yousefzai R, Singh D, Griffin BP, Schoenhagen P, Kapadia SR, Tuzcu ME. “Significance of Aortic Valve Calcification in Patients With Low-Gradient Low- Flow Aortic Stenosis”. Clin Cardiol. 2013 Oct 7. doi: 10.1002/clc.22212. 

  • Goel SS, Aksoy O, Tuzcu EM, Krasuski RA, Kapadia SR. “Embolization of patent foramen ovale closure devices: incidence, role of imaging in identification, potential causes, and management”. Tex Heart Inst J. 2013; 40(4): 439-44. 

  • Aksoy O, O’Brien B, Menon V. “Management of Aortic Stenosis: A Case Based Review”. Cleve Clin J Med. 2013 Apr;80(4):243-52. 

  • Aksoy O, Tuzcu EM, Ellis SG, Whitlow PL, Cam A, Batizy L, Agarwal S, Franco I, Bajzer C, Simpfendorfer C, Raymond R, Nair R, Cho L, Shishehbor MH, Lincoff AM, Kapadia SR. “Percutaneous Coronary Revascularization in Stable Coronary Artery Disease: Lessons from a Single Center Experience”, Catheter Cardiovasc Interv. 2012 Apr 16. doi: 10.1002/ccd.24442. [Epub ahead of print]. 

  • Aksoy O, Goel SS, Houghtaling PL, Williams S, Ruiz-Rodriguez E, Menon V, Kapadia SR, Tuzcu EM, Blackstone E, Griffin BP. “Do Bisphosphonates Slow the Progression of Aortic Stenosis?”, J Am Coll Cardiol. 2012 Apr 17; 59(16):1452-9. doi: 10.1016/j.jacc.2012.01.024. 

  • Goel SS, Agarwal S, Tuzcu EM, Ellis SG, Svensson LG, Zaman T, Bajaj N, Joseph L, Patel NS, Aksoy O, Stewart WJ, Griffin BP, Kapadia SR. “Percutaneous Coronary Intervention in Patients with Severe Aortic Stenosis: Implications for Transcatheter Aortic Valve Replacement”, Circulation. 2012 Feb 28;125(8):1005-13. Epub 2012 Jan 26. 

  • Aksoy O, Cam A, Agarwal S, Yousefzai R, Krishnaswamy A, Goel SS, Griffin BP, Schoenhagen P, Kapadia SR, Tuzcu EM. “Significance of Aortic Valve Calcification in Patients with Low Gradient Low Flow Aortic Stenosis”, Manuscript in Submission. 

  • Goel SS, Tuzcu EM, Agarwal S, Aksoy O, Krishnaswamy A, Griffin BP, Svensson LG, Kapadia SR. “Comparison of ascending aortic size in patients with severe bicuspid aortic valve stenosis treated with versus without a statin drug”, Am J Cardiol. 2011 Nov 15; 108 (10):1458-62. 

  • Aksoy O, Kapadia SR, Bajzer C, Clark WM, Shishehbor MH. “Carotid stenting vs surgery: Parsing the risk of stroke and MI”, Cleve Clin J Med. 2010 Dec; 77(12):892-902. 
  • Aksoy O, Yousefzai R, Singh D, Agarwal S, O'Brien B, Griffin BP, Kapadia SR, Tuzcu EM, Penn MS, Nissen SE, Menon V. “Cardiogenic Shock in the setting of severe Aortic Stenosis: The role for Intra-Aortic Balloon Pump Support”, Heart. 2011 May; 97(10):838-43. Epub 2010 Oct 20. 

  • Aksoy O, Meyer LT, Cabell CH, Kourany WM, Pappas PA, Sexton DJ. “Gender Differences in Infective Endocarditis: Pre- and co-morbid conditions lead to different management and outcomes in female patients”, Scand J Infect Dis. 2007; 39 (2):101-7. 

  • Aksoy O, Sexton DJ, Wang A, Pappas PA, Kourany W, Chu V, Fowler VG Jr, Woods CW, Engemann JJ, Corey GR, Harding T, Cabell CH. “Early surgery in patients with infective endocarditis: a propensity score analysis”, Clin Infect Dis. 2007 Feb 1;44 (3):364-72. 

  • Chu VH, Sexton DJ, Cabell CH, Reller LB, Pappas PA, Singh RK, Fowler VG Jr, Corey GR, Aksoy O, Woods CW. “Repeat Infective Endocarditis: Differentiating Relapse from Reinfection” Clin Infect Dis. 2005 Aug 1; 41(3):406-409. 

  • Gaca JG, Lesher A, Aksoy O, Ruggeri ZM, Parker W, Davis RD. “The role of the porcine von Willebrand factor: baboon platelet interactions in pulmonary xenotransplantation”, Transplantation. 2002 Dec 15; 74(11):1596-603. 

  • Gaca JG, Lesher A, Aksoy O, Gonzalez-Stawinski GV, Platt JL, Lawson JH, Parker W, Davis RD. “Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation”, Transplantation. 2002 Jun 15; 73(11):1717-23. 

  • Gaca JG, Lee W, Aksoy O, Braedehoeft SJ, Gonzalez-Stawinski GV, Parker W, Davis RD. “Evidence for polyreactive xenoreactive antibodies in the repertoire of human anti-swine antibodies: the 'next' humoral barrier to xenotransplantation?”, Transpl Immunol. 2001 Oct; 9(1):19-27. 

Awards

  • Super Doctors® Southern California 2021
  • Super Doctors® Southern California 2020
  • Super Doctors® Southern California 2019
  • Super Doctors® Southern California Rising Stars 2017
  • Super Doctors® Southern California Rising Stars 2016
  • Super Doctors® Southern California Rising Stars 2015
  • Cleveland Clinic Innovator Award 2013
  • Johns Hopkins University; Dept. of Medicine; Teacher of the Year Award 2008