Simon W. Beaven

Simon W. Beaven, PhD, MD

Gastroenterology
Primary Location
UCLA Health Westwood Hepatology and Liver Transplant
200 Medical Plaza
214
Los Angeles, California 90095
Phone
Fax
310-794-4337

About

Dr. Beaven attended Stanford University where he majored in mathematics with honors in humanities. He went on to receive his MD from the University of California, San Francisco, and received the Dean’s Research Prize for work he performed in the laboratory of Dr. Scott Friedman under a Howard Hughes Medical Student Research Fellowship. Dr. Beaven completed internal medicine residency training at the Brigham & Women’s Hospital and Harvard Medical School in Boston. He came to UCLA in 2003 as a fellow in digestive diseases where he completed his gastroenterology fellowship. During this period, Dr. Beaven continued his research training and received a PhD with Dr. Peter Tontonoz in the Howard Hughes Medical Institute and Department of Pathology. His doctoral work focused on cholesterol and lipid metabolism as it pertains to an important clinical problem: the metabolic syndrome. His research interests include nuclear receptor signaling and the relationship of inflammation to lipid metabolism during chronic liver injury.

Dr. Beaven is presently the Chief of Gastroenterology and Hepatology at the Olive View - UCLA Medical Center. At his clinic in the Pfleger Liver Institute on the UCLA Westwood Campus he sees patients with all types of liver diseases including fatty liver [non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH)], viral hepatitis (HAV, HBV, HCV), autoimmune diseases of the liver [autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosis cholangitis (PSC)] and metabolic liver diseases (hemochromatosis, Wilson disease, alpha-1- antitrypsin deficiency). Patients with fatty liver are often seen in conjunction with our multi-disciplinary group, COMET (Center for Obesity and Metabolic Health), as we are able to offer an integrated approach to treating the metabolic syndrome including bariatric surgery. Additionally, Dr. Beaven has a particular interest in rare diseases of the liver and gastrointestinal tract. He is a representative of the American Porphyria Foundation and sees patients with all types of porphyria.

Academic Appointments

  • Assistant Professor of Medicine, David Geffen School of Medicine at UCLA

Additional Education/Certification

  • PhD Cellular and Molecular Pathology, UCLA, 2010

Education

Medical Board Certifications

Gastroenterology, American Board of Internal Medicine, 2007

Fellowship

UCLA School of Medicine, 2008

Residency

Brigham and Women's Hospital, 2003

Internship

Brigham and Women's Hospital, 2002

Degree

UCLA School of Medicine, PhD, 2010

Locations

UCLA Health Westwood Hepatology and Liver Transplant

Hospital Affiliations

Ronald Reagan UCLA Medical Center

Videos

Research

Interests

  • Hepatology
  • Metabolic Syndrome
  • Fatty Liver
  • NAFLD and NASH
  • Cholesterol and Fat Metabolism
  • Nuclear Receptors
  • Chronic Viral Hepatitis
  • Liver Cancer
  • Liver Fibrosis

Publications

  1. Beaven SW, Wroblewski K, Wang J, Hong C, Bensinger S, Tsukamoto H, Tontonoz P. " Liver X Receptor Signaling is a Determinant of Stellate Cell Activation and Susceptibility to Fibrotic Liver Disease." Gastroenterology. 2010 Dec 3. [Epub ahead of print]
  2. Beaven SW & Tontonoz P. "Nuclear receptors in lipid metabolism: Targeting the heart of dyslipidemia." Annual Reviews of Medicine, 57:313-29. 2006.
Link to my PubMed publications >