Steven J. Jonas, MD, PhD

Steven J. Jonas, MD, PhD

Pediatric Hematology Oncology

About

Dr. Jonas is a UCLA physician-scientist specializing in Pediatric Hematology/Oncology. He received a bachelor's degree in materials science & engineering and a master's degree in biomedical engineering prior to starting his medical training to pursue his M.D. and his Ph.D. degrees at UCLA through its NIH-supported Medical Scientist Training Program. Dr. Jonas completed his pediatric residency and fellowship training in pediatric hematology/oncology at UCLA Mattel Children's Hospital where he was the first trainee in a specialized physician-scientist track established by the Department of Pediatrics at the UCLA David Geffen School of Medicine.

He leads a multidisciplinary research team that targets the development and application of new nanotechnologies and methods to support the childhood cancer and regenerative medicine research communities in accelerating the discovery and implementation of innovative gene therapy approaches and diagnostic strategies. His research is primarily focused on the design of nanotechnologies that enable rapid, safe, cost-effective, and efficient delivery of genes and genome-editing machinery to immune and stem cells for manufacturing new gene and cellular therapies.

In 2019, Dr. Jonas received the prestigious Director's Early Independence Award from the National Institutes of Health. He is a member of the California NanoSystems Institute, the UCLA Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, and the Jonsson Comprehensive Cancer Center and is a Young Investigator awardee of the Alex's Lemonade Stand Foundation for Childhood Cancer Research, the Hyundai Hope on Wheels Foundation, and the Tower Cancer Research Foundation.

Education

Medical Board Certifications

Pediatrics, American Board of Pediatrics, 2017

Fellowship

UCLA School of Medicine: Dept of Pediatric Hematology Oncology, 2018

Residency

UCLA School of Medicine, 2015

Degree

UCLA School of Medicine, MD, 2012

Hospital Affiliations

Research

Publications

  1. Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells
    Published in Proceedings of the National Academy of Sciences on Tuesday May 19, 2020.
  2. Dual Supramolecular Nanoparticle Vectors Enable CRISPR/Cas9-Mediated Knockin of Retinoschisin 1 Gene—A Potential Nonviral Therapeutic Solution for X-Linked Juvenile Retinoschisis
    Published in Advanced Science on Thursday April 16, 2020.
  3. Lipid Bicelle Micropatterning Using Chemical Lift-Off Lithography
    Published in Applied Materials & Interfaces on Monday February 24, 2020.
    An Absence of Lamin B1 in Migrating Neurons Causes Nuclear Membrane Ruptures and Cell Death
    Published in Proceedings of the National Academy of Sciences on Tuesday December 3, 2019.
  4. Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer
    Published in Applied Materials & Interfaces on Wednesday March 20, 2019.
  5. Precision-Guided Nanospears for Targeted and High-Throughput Intracellular Gene Delivery
    Published in ACS Nano on Wednesday March 14, 2018.
  6. Precision Medicine in Pediatric Neurooncology: A Review
    Published in ACS Chemical Neuroscience on Monday December 4, 2017.
  7. Multiple-Patterning Nanosphere Lithography for Fabricating Periodic Three-Dimensional Hierarchical Nanostructures
    Published in ACS Nano on Thursday September 28, 2017.
  8. Hydrophobic Surfaces for Enhanced Differentiation of Embryonic Stem Cell-Derived Embryoid Bodies
    Published in Proceedings of the National Academy of Sciences on Friday September 12, 2008.
Link to Dr. Jonas's bibliography >

Awards

  • Super Doctors® Southern California Rising Stars 2021
  • Super Doctors® Southern California Rising Stars, 2020
  • NIH Director’s Early Independence Award, 2019
  • Nancy Ann Mendiburu Outstanding Advance in Cancer Research Award, 2019
  • Hyundai Hope on Wheels Scholar Award, 2019
  • Tower Cancer Research Foundation Career Development Award, 2018
  • UCLA Department of Chemistry & Biochemistry Postdoctoral Scholar Award, 2018
  • Society for Pediatric Research/Pediatric Academic Societies Fellow’s Basic Science Award, 2018
  • Hyundai Hope on Wheels Young Investigator Award, 2017
  • Alex’s Lemonade Stand Young Investigator Award, 2017