Susanne B. Nicholas

Susanne B. Nicholas, MD, PhD

Nephrology
Primary Location
Connie Frank Kidney Transplant Center
200 Medical Plaza
565
Los Angeles, California 90095
Phone
Fax
310-825-9170

Education

Medical Board Certifications

Nephrology, American Board of Internal Medicine, 2002
Internal Medicine, American Board of Internal Medicine, 1994

Fellowship

UCLA School of Medicine, 1998

Residency

VA Greater Los Angeles Healthcare System, 1992

Internship

VA Greater Los Angeles Healthcare System, 1990

Degree

UC San Diego School of Medicine, MD, 1989

Locations

Hospital Affiliations

Ronald Reagan UCLA Medical Center

Research

Interests

Dr. Nicholas is a tenured Associate Professor of Medicine at UCLA in the Division of Nephrology where she maintains her clinical responsibilities, and the Division of Endocrinology, Diabetes and Hypertension, where she conducts her research. She is also a Clinical Hypertension Specialist. Dr. Nicholas’ research interests are to: understand and identify key factors that promote the pathogenesis of diabetic kidney disease (DKD); uncover and validate novel biomarkers that may predict DKD progression; and to quantify renal structural changes associated with DKD in response to novel therapeutics, using stereology principles. Her research over the past 15+ years has led to the identification of a novel biomarker of DKD, which is being validated in clinical studies.

Publications

Link to my PubMed publications >

  1. S.B. Nicholas. Structural Predictors of Renal Function Decline. Clin J Am Soc Nephrol. 2016 Jan 20
  2. S.B. Nicholas, K. Kalantar-Zadeh, K.C, Norris. Socioeconomic influences on health outcomes- implications for CKD. Advances in Chronic Kidney Disease. 2015 Jan;22(1):6-15
  3. S.B. Nicholas: Diabetic Kidney Disease: in Chronic Kidney Disease Clinical Practice Recommendations for Primary Care Physicians and Healthcare Providers. A Collaborative Approach. 7th Edition. 2015
  4. SK Sinha, KC Norris, TB Rajavashisth, M Shaheen, D Pan, SB Nicholas. Race/Ethnicity Modify the Level of Inflammation and its Association with Kidney Disease in Diabetic Patients. Diabetes Care. 2014
  5. MA Aminzadeh, SB Nicholas* (*co-first authors), KC Norris, ND Vaziri. Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy. Nephrology Dialysis and Transplantation 2013 Mar 19
  6. S.B. Nicholas, J. Yuan, A. Aminzadeh, K.C. Norris, A. Crum, N.D. Vaziri. Salutary effect of a novel antioxidant on adenine induced chronic progressive tubulointerstitial nephropathy. Am J. Trans Res. 2012;4(3):257-68. Epub 2012 Jul 20
  7. S.B. Nicholas, J.M. Basgen, S. Sinha. Using Stereologic Techniques to Count Podocytes in the Mouse: Shifting the Paradigm (original report- Laboratory Investigation). Am Jour Nephrol, 2011;33 Suppl 1:1-7
  8. S. B. Nicholas, J. Liu, J. Kim, Y. Ren, L. Nguyen, W.A. Hsueh. Critical Role of Osteopontin in the Diabetic Kidney. Kidney Int. 2010 Apr;77(7):588-600
  9. JR Schelling*, HE Abboud*, SB Nicholas*, (*co-first authors), MV Pahl, JR Sedor, SG Adler, NH Arar, DW Bowen, RC Elston, BI Freedman, KAB Goddard, X Guo, RL Hanson, E Ipp, SK Iyengar, G Jun, WHL Kao, BS Kasinath, PL Kimmel, MJ Klag, WC Knowler, RG Nelson, RS Parekh, SR Quade, SS Rich, MF Saad, M Scavini, MW Smith, K Taylor, CA Winkler, PG Zager, VO Shah, on behalf of the Family Investigation of Nephropathy and Diabetes Research Group. Genome-wide Scan for Estimated GFR in Multi-Ethnic Diabetic Populations: The Family Investigation of Nephropathy and Diabetes Diabetes. 2008 Jan;57(1):235-43
  10. S. B. Nicholas, E. Aguiniga, J. Wong, N. Govindarajan, J. Kim, A. Collins, W. A. Hsueh. Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy. Kidney Int. 67(4):1297-1307, 2005

Awards

  • Mats Wahlstrom Visiting Professor, Division of Renal Diseases and Hypertension
  • University of Colorado Anschutz, Medical Campus, 2015
  • Minority Access, Inc. National Role Model Faculty Researcher Award, 2010