Dr. Sallam is Vice Chair and Associate Professor in the Department of Medicine at the David Geffen School of Medicine at UCLA and a clinical cardiologist at Ronald Reagan UCLA Medical Center. He is a member of the Atherosclerosis Research Unit and Cardiovascular Theme Initiative at UCLA. Dr. Sallam graduated from the University of California, Irvine School of Medicine. He completed residency and chief residency training in Internal Medicine at Yale, followed by Cardiology fellowship training at UCLA. Dr. Sallam graduated from the STAR program at UCLA earning a Ph.D. in Molecular, Cellular and Integrative Physiology in the HHMI Lab of Peter Tontonoz. He joined the UCLA faculty after fellowship, where his research investigates the role of novel transcription factor regulatory circuits in cardiometabolic disease.
In 2015, Dr. Sallam has been awarded the Lauren B. Leichtman and Arthur E. Levine Cardiovascular Discovery Fund investigatorship at UCLA. Dr. Sallam is the recipient of an NIH K Award, American College of Cardiology Presidential Career Development Award, American Heart Association Early Career Investigator recognition, and American Society for Clinical Investigation Young Investigator Award. Dr. Sallam currently serves as co-director of the UCLA Center for Cholesterol Management and Executive Co-Director of the UCLA Specialty Training and Advanced Research (STAR) Program.
Medical Board Certification
Areas of Focus
- Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P. Feedback modulationof cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature. 2016 May 11;534(7605):124-8.
- Wong MD, Guerrero L, Sallam T, Frank JS, Fogelman AM, Demer LL. Outcomes of a Novel Training Program for Physician-Scientists: Integrating Graduate Degree Training With Specialty Fellowship. J Grad Med Educ. 2016 Feb;8(1):85-90.
- Edris A, Gordin J, Sallam T, Wachsner R, Meymandi S, Traina M. Facilitated patent haemostasis after transradial catheterisation to reduce radial artery occlusion. EuroIntervention. 2015 Nov;11(7):765-71.
- Mitchell A, Misialek JR, Folsom AR, Duprez D, Alonso A, Jerosch-Herold M, Sanchez OA, Watson KE, Sallam T, Konety SH. Usefulness of N-terminal Pro-brain Natriuretic Peptide and Myocardial Perfusion in Asymptomatic Adults (from the Multi-Ethnic Study of Atherosclerosis). Am J Cardiol. 2015 May 15;115(10):1341-5.
- Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H,Hevener AL, de Cabo R, Cohen P. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab.2015 Mar 3;21(3):443-54.
- Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell Metab. 2015 Feb 3;21(2):334-46.
- Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. J Lipid Res. 2014 Jun;55(6):1120-30.
- Edris A, Sallam T, Traina MI. A wrong turn in embryologic development: a case of a primary right ventricular intracardiac tumor. J Am Coll Cardiol. 2014 Apr 8;63(13):e29. 24530678.
- Sallam T, Watson KE. Predictors of cardiovascular risk in women. Womens Health. (Lond Engl). 2013 Sep;9(5):491-8.
- Sallam T, Cheng H, Demer LL, Tintut Y. Regulatory circuits controlling vascular cell calcification. Cell Mol Life Sci. 2013 Sep;70(17):3187-97.
In the News
- Gene therapy using ‘junk DNA’ could lower risk for heart disease (Source: UCLA Health News)
- Familial Hypercholesterolemia: “Junk” RNA May Facilitate Gene Therapy (Source: MedicalResearch.com)
- LXR maintains cholesterol balance through a noncoding RNA (Source: ScienceSignaling)
- 2 doctors go from colleagues to friends as one saves the other's life (Source: UCLA Health News)
- Nearly 40 years after a life-saving heart procedure, a joyous 100th birthday celebration (Source: UCLA Health News)
Note: News links may expire without notice.
- Inducted into American Society for Clinical Investigation, 2022
- Transformational Project Grant Award, American Heart Association, 2020
- Burroughs Wellcome Fund Career Award for Medical Scientist, 2017
- American Society for Clinical Investigation Young Physician-Scientist Award, 2016
- American Heart Association Early career Award (ATVB Council)-Finalist, 2015
- American College of Cardiology Presidential Career Development Award, 2015
- 1st place - Department of Medicine Research Day UCLA Basic Science-Junior Faculty, 2014
- American Heart Association Postdoctoral Fellowship, 2013
- Chief Fellow, UCLA Specialty Training and Advanced Research (STAR) Program, 2013
- UCLA Division of Cardiology Fellow Research Award, 2013
- Chief Fellow, UCLA Division of Cardiology, 2013
- UCLA Division of Cardiology Fellow Teaching Award, 2012
- Tibor Fabian Research Award-UCLA STAR Program, 2011
- Chief Resident in Internal Medicine, Yale New Haven Hospital, 2009
- Yale New Haven Hospital Chief Award, 2008
- James S McGoey Research Award-Medical School, 2004
- Inductee - Gold Humanism Honor Society, 2004
- President American Medical Association-Medical Student Section, 2003
- UCI Academic Excellence Award, 2002
- UCI College of Medicine Service Award, 2002