Xinjiang Cai, MD, PhD

Xinjiang Cai, MD, PhD

Accepting new patients
Primary Location
UCLA General Cardiology Med Plaza 100 Ste. 545
100 Medical Plaza
Suite 545
Los Angeles, California 90095


Dr. Cai is a cardiologist and physician scientist at UCLA Health. He is passionate about improving Patient-Centered Clinical Care and Cardiovascular Health in patients and the general population. He is also enthusiastic about Basic and Translational Cardiovascular Research which will help improve patient care.

He completed Cardiology Fellowship in the Specialty Training and Advanced Research (STAR) Program at the University of California, Los Angeles. Prior to that, he received Internal Medicine Residency Training and served as a PGY-3 Chief Resident at the Icahn School of Medicine at Mount Sinai (VA) in New York.

Dr. Cai obtained his PhD degree in Cardiovascular Molecular Biology at the University of Calgary, Canada, followed by basic research and translational medicine training at Duke University Medical Center, NYU Medical Center, and Rutgers University Robert Wood Johnson University Hospital. During his residency and fellowship training, he continued his passion on basic and translational research as a Research Fellow at the Cardiovascular Research Centers at Mount Sinai and UCLA.


Chinese - Mandarin, English


Medical Board Certification

Internal Medicine, American Board of Internal Medicine, 2018


University of California, Los Angeles, 2022


Icahn School of Medicine at Mount. Sinai (Bronx), 2018


University of Calgary, PhD, 2004
Central South University Xiangya School of Medicine, MD, 1996


UCLA General Cardiology Med Plaza 100 Ste. 545

Hospital Affiliations

Ronald Reagan UCLA Medical Center

Areas of Focus

Dyspnea on exertion
Congestive heart failure (chf)
Chest pain
Cardiac arrhythmias



  • Cardiovascular Disease
  • Atherosclerosis
  • Heart Failure
  • Cellular Signaling
  • Vascular Biology


Link to a complete list of publication

  1. Cai, X., Allison, M.A., Ambale-Venkatesh, B., Jorgensen, N.W., Lima, J.A.C., Muse, E.D., McClelland, R.L, Shea, S., Lebeche, D. (2022) Resistin and risks of subclinical heart failure and cardiac fibrosis: the Multi-Ethnic Study of Atherosclerosis (MESA) Study. European Society of Cardiology: Heart Failure [Epub ahead of Print]
  2. Yao, J., Ma, F., Zhang, L., Zhu, C., Jumabay, M., Yao, Z., Wang, L., Cai, X., Zhang, D., Qiao, X., Shivkumar, K., Pellegrini, M., Yao, Y., Wu, X., Bostrom, K.I. (2022) Single-cell RNA-seq identifies dynamic cardiac transition program from adipose derived cells induced by leukemia inhibitory factor. Stem Cells [Epub ahead of Print]
  3. *Cai, X., Shahandeh, N., Ji, J., Finn, J.P., Fishbein, G.A., Biniwale, R.M., Ardehali, A., Sayah, D.M., Yang, E.H. (2022) Ascending aortic pseudoaneurysm: a rare complication of transcatheter aortic valve replacement and thoracic surgery. Circulation: Cardiovascular Imaging. 15, e014076
  4. Marchant, J.S., Gunaratne, G.S., Cai, X., Slama, J.T., Patel, S. (2022) NAADP-binding proteins find their identity. Trends in Biochemical Sciences. 47, 235-249.
  5. Li, Z.H., King, T.P., Ayong, L., Asady, B., Cai, X., Rahman, T., Vella, S.A., Patel, S., Moreno, S.N. (2021) A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii.  Nature Communications. 12: 5802.
  6. Yao, J., Wu, X., Qiao, X., Zhang, D., Zhang, L., Ma, J.A., Cai, X., Bostrom, K.I., Yao, Y. (2021) Shifting osteogenesis in vascular calcification. JCI Insight, 6: e143023.
  7. Zhang, D., Qiao, X., Yao, J., Zhang, L., Wu, X., Ma, J., Cai, X., Bostrom, K., Yao, Y. (2021) Pronethalol reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to ameliorate vascular calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 931–933.
  8. Qiao, X., Zhang, D., Zhang, L., Yao, J., Wu, X., Cai, X., Bostrom, K., Yao, Y. (2020) Pronethalol decreases RBPJk to reduce Sox2 in cerebral arteriovenous malformation. Vascular Medicine. 25, 569-571.