
Zain A. Al-Safi, MD
Reproductive Endocrinology and Infertility
Accepting new patients
Primary Location
Santa Monica OBGYN Specialty Suite
1245 16th Street
Suite 202
Santa Monica, California 90404
Suite 202
Santa Monica, California 90404
Phone
Fax
424-529-6253
About
Dr. Zain Al-Safi is committed to providing excellent patient care and advanced reproductive health services.
His clinical interests include infertility, polycystic ovary syndrome, oncofertility, and reproductive surgery.
"I look forward to assisting you on your journey to achieve pregnancy."
Membership, Medical Organizations
- American Congress of Obstetricians and Gynecologists (ACOG)
- American Society for Reproductive Medicine (ASRM)
Board Certification:
- American Board of Obstetrics and Gynecology for subspecialty Reproductive Endocrinology and Infertility.
Languages
Education
Medical Board Certifications
Reproductive Endocrinology/Infertility, American Board of Obstetrics and Gynecology, 2017
Obstetrics and Gynecology, American Board of Obstetrics and Gynecology, 2013
Fellowship
Reproductive Endocrinology and Infertility, University of Colorado Hospital, 2015
Residency
Obstetrics & Gynecology, Wayne State University School of Medicine, 2012
Internship
Obstetrics & Gynecology, University of Al-Nahrain, 2005
Degree
MD, University of Al-Nahrain, 2004
Recognitions
- Top Doctors, Los Angeles Magazine, 2023
- Super Doctors® Southern California 2021, 2022, 2023
- Top Doctors, Los Angeles Magazine, 2018-2021 See More
Locations
Santa Monica
Santa Monica OBGYN Specialty Suite
Santa Monica OBGYN Specialty Suite
Obstetrics and Gynecology| Women's Health| Gynecologic Oncology

Hospital Affiliations
Ronald Reagan UCLA Medical Center
UCLA Santa Monica Medical Center
Areas of Focus
Female infertility
Recurrent pregnancy loss
Fertility preservation
Oncofertility
Polycystic ovary syndrome
In vitro fertilization
Videos
Embryo Transfer, Cryopreservation & IVF Results
Egg Freezing and Female Fertility Preservation
Research
Interests
- Obesity and reproduction
- Infertility treatment outcomes
- Menopausal health
Publications
- Al-Safi ZA, Polotsky A, Chosich J, Roth L, Allshouse AA, Bradford AP, Santoro N. Evidence for Disruption of Normal Circadian Cortisol Rhythm in Women with Obesity. Gynecol Endocrinol. 2017. Epub ahead of print. [PMID: 29068243].
- Sundheimer LW, Liu L, Buyalos RP, Hubert G, Al-Safi Z, Shamonki M. Diagnosis of Parental Balanced Reciprocal Translocations by Trophectoderm Biopsy and Comprehensive Chromosomal Screening. J Assist Reprod Genet. 2017. Epub ahead of print. [PMID: 28900794].
- Kroener L, Dumesic D, Al-Safi Z. Use of Fertility Medications and Cancer risk: A Review and Update. Curr Opin Obstet Gynecol. 2017 Aug;29(4):195-201. [PMID: 28538003].
- Al-Safi ZA, Liu H, Carlson NE, Chosich J, Harris M, Bradford AP, Robledo C, Eckel RH, Polotsky AJ. Omega-3 Fatty Acid Supplementation Lowers Serum FSH in Normal Weight but not Obese Women. J Clin Endocrinol Metab, 2016; 101(1): 324-333. [PMID: 26523525].
- Al-Safi ZA, Liu H, Carlson NE, Chosich J, Lesh J, Robledo C, Bradford AP, Gee NA, Phang T, Santoro N, Kohrt W, Polotsky AJ. Estradiol Priming Improves Gonadotrope Sensitivity and Pro-Inflammatory Cytokines in Obese Women. J Clin Endocrinol Metab, 2015; 100(11): 4372-81 . [PMID: 26425884].
- Al-Safi ZA, Edil BH, Post MD, Pearlman NW, Alvero R. Fertility Preservation in a Patient with Benign Multicystic Peritoneal Mesothelioma. J Surg Oncol, 2014; 110(4): 372-4. [PMID: 24861198].
- Al-Safi ZA, Santoro N. Menopausal Hormone Therapy and Menopausal Symptoms. Fertil Steril, 2014; 101(4): 905-915. [PMID: 24613533].
Recognitions
- Top Doctors, Los Angeles Magazine, 2023
- Super Doctors® Southern California 2021, 2022, 2023
- Top Doctors, Los Angeles Magazine, 2018-2021
- Super Doctors® Southern California Rising Stars, 2020
- Super Doctors®Southern California Rising Stars, 2019
- Society for Reproductive Investigation, SRI-Pfizer President’s Presenter’s Award, SRI Annual Meeting, 2015.
- Endocrine Society, Early Career Forum Travel Award, Endocrine Society Annual Meeting, 2015.
- American Society for Reproductive Medicine Corporate Member Council In-training Travel Grant, ASRM Annual Meeting, 2014.
- Wayne State University / Detroit Medical Center, Administrative Chief Resident Award, 2012
- Wayne State University, Chairman’s Award For Overall Excellence in Obstetrics and Gynecology, 2012
- Wayne State University, Teshima Award For Excellence in Gynecology, 2012
- Wayne State University, Excellence in Academic Achievement Award, 2012
- Wayne State University, Excellence in Reproductive Endocrinology and Infertility Award, 2011
- Wayne State University, Division of Maternal Fetal Medicine, Best Overall Resident Award, 2011
- Wayne State University, Division of Maternal Fetal Medicine, Outstanding Effort Award, 2010
- Sinai Grace Hospital President’s Award for Excellence, 2010