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• Angina

  Angina Pectoris

  Angina pectoris (or simply angina) is chest pain or discomfort that keeps coming back. It happens when some part of your heart doesn't get enough blood and oxygen. Angina can be a symptom of coronary artery disease (CAD).
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• Atherosclerosis

  Atherosclerosis

  Atherosclerosis is a type of thickening or hardening of the arteries caused by a buildup of plaque in the inner lining of an artery. It can increase your risk of heart attack, stroke, and other circulatory conditions.
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• Cardiac Imaging
• Cholesterol

  Cholesterol in the Blood

  The cholesterol in your blood comes from the foods you eat and your liver. Your liver makes all of the cholesterol your body needs. It helps your body make cell membranes, many hormones, and vitamin D. 
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• Coronary Artery Disease

  Coronary Heart Disease

  A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.
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• General Cardiology

  Home Page - Cardiovascular Diseases

  Cardiovascular diseases include coronary heart disease, stroke, high blood pressure, and rheumatic heart disease.
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• Hypertension

  High Blood Pressure/Hypertension

  Blood pressure is the force of the blood pushing against the artery walls. The force is created with each heartbeat as blood is pumped from the heart into the blood vessels. Blood pressure is also affected by the size of the artery walls and how elastic they are. Each time the heart beats (contracts and relaxes), pressure is created inside the arteries. High blood pressure, or hypertension, increases the risk for coronary heart disease (heart attack) and stroke (brain attack).
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• Intermittent Claudication

  Claudication

  Claudication is pain in your thigh, calf, or buttocks that happens when you walk. It may be a symptom of peripheral artery disease (PAD). This is when narrowed or blocked arteries reduce the blood flow to your legs.
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• Ischemia (Heart)
• Nuclear Cardiology
• Syncope

  A Serious Look at Fainting

  Fainting (syncope) is a brief loss of consciousness. This leads to falling down or needing to lie down, followed by a quick recovery. Fainting by itself is not a problem, but it could be a sign of a serious health condition. 
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• Transthoracic Echocardiography

  Transesophageal Echocardiogram

  A transesophageal echocardiogram (TEE) uses echocardiography to assess how well the heart works. During the procedure, a transducer (like a microphone) is lowered into the esophagus. It sends out ultrasonic sound waves at a frequency too high to be heard. When the transducer is placed at certain locations and angles, the ultrasonic sound waves move through the skin and other body tissues to the heart tissues, where the waves bounce or "echo" off of the heart structures.
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1. Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P. Feedback modulationof cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature. 2016 May 11;534(7605):124-8.
2. Wong MD, Guerrero L, Sallam T, Frank JS, Fogelman AM, Demer LL. Outcomes of a Novel Training Program for Physician-Scientists: Integrating Graduate Degree Training With Specialty Fellowship. J Grad Med Educ. 2016 Feb;8(1):85-90.
3. Edris A, Gordin J, Sallam T, Wachsner R, Meymandi S, Traina M. Facilitated patent haemostasis after transradial catheterisation to reduce radial artery occlusion. EuroIntervention. 2015 Nov;11(7):765-71.
4. Mitchell A, Misialek JR, Folsom AR, Duprez D, Alonso A, Jerosch-Herold M, Sanchez OA, Watson KE, Sallam T, Konety SH. Usefulness of N-terminal Pro-brain Natriuretic Peptide and Myocardial Perfusion in Asymptomatic Adults (from the Multi-Ethnic Study of Atherosclerosis). Am J Cardiol. 2015 May 15;115(10):1341-5.
5. Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H,Hevener AL, de Cabo R, Cohen P. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab.2015 Mar 3;21(3):443-54.
6. Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell Metab. 2015 Feb 3;21(2):334-46.
7. Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. J Lipid Res. 2014 Jun;55(6):1120-30.
8. Edris A, Sallam T, Traina MI. A wrong turn in embryologic development: a case of a primary right ventricular intracardiac tumor. J Am Coll Cardiol. 2014 Apr 8;63(13):e29. 24530678.
9. Sallam T, Watson KE. Predictors of cardiovascular risk in women. Womens Health. (Lond Engl). 2013 Sep;9(5):491-8.
10. Sallam T, Cheng H, Demer LL, Tintut Y. Regulatory circuits controlling vascular cell calcification. Cell Mol Life Sci. 2013 Sep;70(17):3187-97.

Laboratory of Tamer Sallam M.D., Ph.D.

Gene therapy using ‘junk DNA’ could lower risk for heart disease - UCLA Health
Familial Hypercholesterolemia: “Junk” RNA May Facilitate Gene Therapy - MedicalResearch.com
LXR maintains cholesterol balance through a noncoding RNA - ScienceSignaling

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• 2016 American Society for Clinical Investigation Young Physician-Scientist Award
• 2015 American Heart Association Early career Award (ATVB Council)-Finalist
• 2015 American College of Cardiology Presidential Career Development Award
• 2014 1st place - Department of Medicine Research Day UCLA Basic Science-Junior Faculty
• 2013 American Heart Association Postdoctoral Fellowship
• 2013 Chief Fellow, UCLA Specialty Training and Advanced Research (STAR) Program
• 2013 UCLA Division of Cardiology Fellow Research Award
• 2013 Chief Fellow, UCLA Division of Cardiology
• 2011 Tibor Fabian Research Award-UCLA STAR Program
• 2012 UCLA Division of Cardiology Fellow Teaching Award
• 2009 Chief Resident in Internal Medicine, Yale New Haven Hospital
• 008 Yale New Haven Hospital Chief Award
• 2004 James S McGoey Research Award-Medical School
• 2004 Inductee - Gold Humanism Honor Society
• 2003 President American Medical Association-Medical Student Section
• 2002 UCI Academic Excellence Award
• 2002 UCI College of Medicine Service Award