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Specialty:
Anatomic Pathology
Department Affiliation:
Pathology
Hospital Affiliation:
Ronald Reagan UCLA Medical Center
State License:
A81305
Phone:
310-825-7230
Health Plans:
Accepted Plans
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About Me

Academic Title: Professor of Pathology and Laboratory Medicine

Department Titles: Chief of Neuropathology, Director of Brain Tumor Translational Resource, Faculty of Brain Research Institute

Specialty: Neuropathology, Surgical Pathology, Autopsy

Dr. Yong obtained a bachelors degree in molecular biology at UC Berkeley and a masters degree in biology (cellular and molecular) at San Francisco State University. For the masters degree, he studied the AIDS retrovirus while in the laboratory of Professor Jay Levy at UCSF. He attended medical school at UCLA where he completed his Honors thesis research with Professor Harry Vinters and graduated as a Deans Scholar. He trained in Pathology and Laboratory Medicine at Massachusetts General Hospital, Harvard Medical School, where he worked in the molecular neuro-oncology laboratory of Dr. David Louis. He completed his neuropathology fellowship at UCLA. He was the Director of Neuropathology at Cedars-Sinai Medical Center. He is currently Chief of Neuropathology at UCLA and Director of the UCLA Brain Tumor Translational Resource as well as of the UCLA Neuropathology Fellowship Program. His research interests include brain tumor neuropathology and biobanking.

Links

uclahealth.org/pathology
uclahealth.org/braintumor
pituitary.ucla.edu

Primary Office
UCLA Pathology & Lab Medicine
10833 Le Conte Ave.
Suite 13-360 CHS
Los Angeles, CA 90095
Get Directions
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Phone
310-825-7230
Medical Board Certifications
Pathology-Anatomic, American Board of Pathology, 1999
Certification 2
Neuropathology, American Board of Pathology, 1999
Fellowship
Neuropathology, UCLA School of Medicine, 1995-1998
Residency
Anatomic & Clinical Pathology, Harvard Medical School/Massachusetts General Hospital, 1991-1995
Degree
UCLA School of Medicine, MD, 1991
Interests
  • Acoustic Neuromas

    Acoustic Neuroma

    Acoustic neuroma is a rare noncancer tumor. It affects hearing and balance when the tumor presses on the nerves in the inner ear.
    Learn more >
  • Brain Tumor

    Brain Tumors: Introduction

    A brain tumor is an abnormal growth of tissue in the brain. There are 2 main types of brain tumors - Primary tumor starts in the brain. The Secondary (metastatic) tumor is from a cancer that starts in another part of the body, then spreads to the brain.
    Learn more >
  • Intracerebral Hemorrhage
  • Muscle Biopsy

    Muscle Biopsy

    A muscle biopsy is a procedure used to diagnose diseases involving muscle tissue. Your healthcare provider will remove tissue and cells from a specific muscle and view them microscopically. Your provider will only need to remove a small piece of tissue from the designated muscle.
    Learn more >
  • Peripheral Nerve
  • Pituitary Tumors

    Pituitary Tumor: Introduction

    A pituitary tumor is a tumor that grows in the pituitary gland. Pituitary cancers are very rare. Most tumors in the pituitary gland are not cancer (benign). They are called adenomas. They don't spread to other parts of the body like cancers do.
    Learn more >
  • Seizure Disorder
  • Spinal Tumor

    Spinal Cord Tumor Overview

    Spinal cord tumors are fairly uncommon. It's much more common to develop a brain tumor than a tumor on the spinal cord. A spinal cord tumor may form inside the spinal cord itself or around the bones that make up the spine.
    Learn more >
Publications

Link to Dr. Yong's MyNCBI publications >

  1. Yong WH, Shabihkhani M, Telesca D, Yang S, Tso JL, Menjivar JC, Wei B, Lucey GM, Mareninov S, Chen Z, Liau LM, Lai A, Nelson SF, Cloughesy TF, Tso CL. Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients. PLoS One. 2015 Oct 27;10(10):e0141334. doi: 10.1371/journal.pone.0141334. eCollection 2015. PubMed PMID: 26506620; PubMed Central PMCID: PMC4624638.
  2. Everson RG, Antonios JP, Lisiero DN, Soto H, Scharnweber R, Garrett MC, Yong WH, Li N, Li G, Kruse CA, Liau LM, Prins RM. Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastoma. Neuro Oncol. 2015 Sep 1. pii: nov153. [Epub ahead of print] PubMed PMID: 26330563.
  3. Masui K, Tanaka K, Ikegami S, Villa GR, Yang H, Yong WH, Cloughesy TF, Yamagata K, Arai N, Cavenee WK, Mischel PS. Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9406-11. doi: 10.1073/pnas.1511759112. Epub 2015 Jul 13. PubMed PMID: 26170313; PubMed Central PMCID: PMC4522814.
  4. Shabihkhani M, Lucey GM, Wei B, Mareninov S, Lou JJ, Vinters HV, Singer EJ, Cloughesy TF, Yong WH. The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings. Clin Biochem. 2014 Mar;47(4-5):258-66. doi: 10.1016/j.clinbiochem.2014.01.002. Epub 2014 Jan 12. Review. PubMed PMID: 24424103; PubMed Central PMCID: PMC3982909.
  5. Lou JJ, Mirsadraei L, Sanchez DE, Wilson RW, Shabihkhani M, Lucey GM, Wei B, Singer EJ, Mareninov S, Yong WH. A review of room temperature storage of biospecimen tissue and nucleic acids for anatomic pathology laboratories and biorepositories. Clin Biochem. 2014 Mar;47(4-5):267-73. doi: 10.1016/j.clinbiochem.2013.12.011. Epub 2013 Dec 18. Review. PubMed PMID: 24362270; PubMed Central PMCID: PMC3976177.
  6. Mareninov S, De Jesus J, Sanchez DE, Kay AB, Wilson RW, Babic I, Chen W, Telesca D, Lou JJ, Mirsadraei L, Gardner TP, Khanlou N, Vinters HV, Shafa BB, Lai A, Liau LM, Mischel PS, Cloughesy TF, Yong WH. Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage. J Neurooncol. 2013 Jul;113(3):365-73. doi: 10.1007/s11060-013-1135-1. Epub 2013 May 3. PubMed PMID: 23640138; PubMed Central PMCID: PMC3886564.
  7. Lou JJ, Andrechak G, Riben M, Yong WH. A review of radio frequency identification technology for the anatomic pathology or biorepository laboratory: Much promise, some progress, and more work needed. J Pathol Inform. 2011;2:34. doi: 10.4103/2153-3539.83738. Epub 2011 Aug 13. PubMed PMID: 21886890; PubMed Central PMCID: PMC3162748.
  8. Leung AA, Lou JJ, Mareninov S, Silver SS, Routbort MJ, Riben M, Andrechak G, Yong WH. Tolerance testing of passive radio frequency identification tags for solvent, temperature, and pressure conditions encountered in an anatomic pathology or biorepository setting. J Pathol Inform. 2010 Oct 1;1:21. doi: 10.4103/2153-3539.70710. PubMed PMID: 21031010; PubMed Central PMCID: PMC2956174.
  9. Sun J, Masterman-Smith MD, Graham NA, Jiao J, Mottahedeh J, Laks DR, Ohashi M, DeJesus J, Kamei K, Lee KB, Wang H, Yu ZT, Lu YT, Hou S, Li K, Liu M, Zhang N, Wang S, Angenieux B, Panosyan E, Samuels ER, Park J, Williams D, Konkankit V, Nathanson D, van Dam RM, Phelps ME, Wu H, Liau LM, Mischel PS, Lazareff JA, Kornblum HI, Yong WH*, Graeber TG*, Tseng HR*. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. Cancer Res. 2010 Aug 1;70(15):6128-38. doi: 10.1158/0008-5472.CAN-10-0076. Epub 2010 Jul 14. PubMed PMID: 20631065; PubMed Central PMCID: PMC3163840. (*Corresponding authors)
  10. Yong WH, Butte PV, Pikul BK, Jo JA, Fang Q, Papaioannou T, Black K, Marcu L. Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy. Front Biosci. 2006 May 1;11:1255-63. PubMed PMID: 16368511; PubMed Central PMCID: PMC2991156.
Awards
Lucien J. Rubinstein Award
Moore Award
Johnny Mercer Foundation Research Award
William H. Yong, MD click here to update your profile
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