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• Bone Marrow Transplant

  Bone Marrow Transplantation

  Bone marrow transplant (BMT) is a special therapy for patients with certain cancers or other diseases. A bone marrow transplant involves taking cells that are normally found in the bone marrow (stem cells), filtering those cells, and giving them back either to the donor (patient) or to another person. 
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• Chronic Myelogenous Leukemia

  Chronic Lymphocytic Leukemia (CLL): Introduction

  Leukemia is cancer that starts in the bone marrow. This is where new blood cells are made. Chronic lymphocytic leukemia (CLL) is a type of leukemia that starts in the lymphoid cells in the bone marrow. These are cells that normally help the body fight infection. 
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• General Hematology

  Hematology

  Hematology is the study of blood and blood disorders. Hematologists and hematopathologists are highly trained healthcare providers who specialize in diseases of the blood and blood components. These include blood and bone marrow cells. Hematological tests can help diagnose anemia, infection, hemophilia, blood-clotting disorders, and leukemia.
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• Hematologic Malignancies
• Leukemia

  Leukemia Index

  Detailed information on Leukemia in childhood, including symptoms, staging, diagnosis, and treatment. There are several types of leukemias that require clinical care by a physician or other healthcare professional. Learn more about Overview of Leukemias; Acute Lymphocytic Leukemia; Chronic Lymphocytic Leukemia; Acute Myelogenous Leukemia; Chronic Myelogenous Leukemia.
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• Multiple Myeloma

  Multiple Myeloma: Introduction

  Multiple myeloma is cancer that starts in your bone marrow. Specifically, it starts in plasma cells. In multiple myeloma, normal plasma cells go through a series of changes. This can eventually cause excess cell growth. It can also cause tumors to form in your bones.
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• Myeloid Metaplasia

  Acute Myeloid Leukemia (AML): Introduction

  Leukemia is cancer that starts in the bone marrow, which is where new blood cells are made. The bone marrow is a thick, sponge-like tissue in the center of certain bones. Read on to learn more.
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• Stem Cell Transplant

  Hodgkin Lymphoma: Stem Cell Transplant

  A stem cell transplant uses young blood cells, called stem cells, to replace bone marrow that has been destroyed by cancer treatment. It is a complex treatment and can cause serious side effects. Here's what you need to know.
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1. Seet, C.S., He C, Bethune M.T., Li, S, Chick, B., Gschweng, E.H., Zhu, Y., Kim K., Kohn, D.B., Baltimore, D., *Crooks GM, *Montel-Hagen A. (2017) Generation of mature T cells from human hematopoietic stem-progenitor cells in artificial thymic organoids. Nature Methods, 2017 Apr 3.
2. Seet C.S., Li, S., Chick, B., Casero, D., Gschweng, E.H., Zhu, Y., Miao, R., Montel-Hagen, A., Kohn, D.B., Sehl, M., Crooks, G.M., Notch Signaling Promotes the Differentiation of Human CLEC9A+ Dendritic Cells from Hematopoietic Stem and Progenitor Cells, Oral Presentation, American Society of Hematology (ASH) 59th Annual Meeting, Atlanta, GA, Dec. 11, 2017
3. Montel-Hagen, A.*, Seet C.S.* (*co-first authors), Li, S., Chick, B., Chang, P., Zhu, Y., He, C., Lopez, S., Crooks, G.M., In Vitro Generation of Human Pluripotent Stem Cell-Derived T Cells for Immunotherapy, Oral Presentation, American Society of Hematology (ASH) 59th Annual Meeting, Atlanta, GA, Dec. 11, 2017
4. Casero D., Sandoval S., Seet C.S., Scholes J., Zhu Y., Ha V., Parekh C, Crooks G.M. (2015) Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages. Nature Immunology, Dec;16(12):1282-91
5. Seet C.S., Crooks G.M., (2025), Chapter 74: Lymphopoiesis, Williams Hematology, 9th Edition, Kaushansky K. et al. (Editor), McGraw-Hill Education
6. Berent-Maoz B., Montecino-Rodriguez E., Fice M., Casero D, Seet C.S., Crooks G. M., Lowry W., Dorshkind K. (2015) The Expansion of Thymopoiesis in Neonatal Mice is Dependent on Expression of High mobility group A 2 protein (Hmga2), PLOS One, May 1;10(5):e0125414.
7. Kohn L. A., Seet C.S., Scholes J., Codrea F., Chan R., Zaidi-Merchant S., Zhu Y. De Oliveira S., Kapoor N., Shah A., Abdel-Azim H., Kohn D.B., Crooks G.M. (2014) Human lymphoid development in the absence of common y-chain receptor signaling, J Immunol. Jun 1;192(11):5050-8.
8. Zhang J.*, Seet C.S.* (*co-first authors), Sun C., Li J., You D., Volk A., Breslin P., Li X., Wei W., Qian Z., Zeleznik-Le, N.J., Zhang Z., Zhang J. (2013) p27kip1 maintain a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia. Molecular Oncology, Dec;7(6):1069-82.

Artificial organ may help patients form the cancer-fighting cells they need - digitaltrends.com
Artificial thymus developed at UCLA can produce cancer-fighting T cells from blood stem cells - UCLA Newsroom

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• NIH/UCLA CTSI KL2 Translational Science Award, 2017, 2018
• Broad Stem Cell Research Center at UCLA Clinical Fellow, 2016, 2017, 2018
• 1st Place, Department of Medicine Poster Competition, David Geffen School of Medicine at UCLA, 2017
• UCLA CTSI Core Voucher Award, 2017
• Career Development Award, Tower Cancer Research Foundation, 2015
• Research Innovator Award, Department of Medicine, David Geffen School of Medicine at UCLA, 2015
• Young Investigator Award at ImmunologyLA, American Association of Immunologists, 2015
• NIH T32 Hematology Training Grant, 2013-2016
• Fellow Teaching Award Nominee, Department of Medicine, David Geffen School of Medicine at UCLA, 2012