Clinical Trials and Studies

3-D imaging in colonic mucosa of IBS-D, IBS-C and healthy controls
Lin Chang, MD, co-director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience, is conducting a study to test a new CLARITY imaging technique to map the colonic mucosa in IBS patients.
You may be eligible if you:
- Between the ages of 18 to 50 years
- Not pregnant or nursing
- No significant neurological, psychological or other health history
Study participation consists of:
- One screening visit
- One sigmoidoscopy procedure
- Online questionnaires
Compensation:
- Earn up to $150
- Free parking provided
For more information: Call 310-206-1656
Protocol ID:IRB#20-000241 UCLA IRB Approved End Date: 02/2023 Committee: Medical IRB 1
AnX NaviCam capsule endoscopy study for gastroparesis and functional dyspepsia
Lin Chang, MD, co-director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience, is conducting a magnetically controlled capsule endoscopy system on gastroparesis and functional dyspepsia patients.
You may be eligible if you:
- Between the ages of 18 to 60 years
- Diagnosed with either functional dyspepsia or gastroparesis
- Not pregnant or nursing
- No significant neurological, psychological or other health history
Study participation consists of:
- One screening visit
- Capsule endoscopy procedure
- Online questionnaires
Compensation:
- Earn up to $150
- Free parking provided
For more information: Call 310-206-1656
Protocol ID:IRB#20-001573 UCLA IRB Approved End Date: 06/2023 Committee: Medical IRB 1
Research on effects of social isolation and discrimination
Arpana Gupta, PhD, G. Oppenheimer Center for Neurobiology of Stress and Resilience, is conducting a study on the effects of stress and discrimination in Mexican and Filipina women.
You may be eligible if you:
- Premenopausal female of Mexican or Filipina ancestry (MUST be of 100 percent Mexican or 100 percent Filipina ancestry)
- Between the ages of 18 to 50 years
- Right-handed
- Not pregnant or nursing
- No significant neurological, psychological or other health history
Study participation consists of:
- Two (2) visits (screening brain MRI)
- Two (2) stool samples
- One (1) blood sample
- Online questionnaires about diet and mood
- Optional follow-up visits at three (3) and six (6) months
Compensation:
- Earn up to $285
- Free parking provided
For more information: Call 310-825-7206
Protocol ID:IRB#20-002326 UCLA IRB Approved End Date: 12/2025 Committee: Medical IRB 3
Study on women and stress
Arpana Gupta, PhD, G. Oppenheimer Center for Neurobiology of Stress and Resilience, is conducting a study comparing women with high and women with low stress.
You may be eligible if you:
- Caucasian female
- Between the ages of 18 to 45 years
- Not pregnant or nursing
- Consider yourself to be either a high stress type person or a low stress type of person
Study participation consists of:
- One (1) phone/Zoom screening
- One (1) 2-hour laboratory stress test day consisting of 4 short cognitive stress tests
- Two (2) finger pricks for blood sample and one (1) small stool sample collected at home
- Online questionnaires
Compensation:
- Earn up to $225
- Free parking provided
- Sponsored by Danone Research
For more information: Call Allison at 310-825-7206
Protocol ID:IRB#20-001921 UCLA IRB Approved End Date: 12/2022 Committee: Medical IRB 3
Cognitive behavioral therapy (CBT) for gastrointestinal pain
Emeran A. Mayer, MD, director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience, is conducting a study to test the effect of cognitive behavioral therapy (CBT) on the brain and gut in irritable bowel syndrome (IBS).
You may be eligible if you:
- Have chronic abdominal pain with altered bowel habits for at least 6 months OR diagnosed with IBS
- Between the ages of 18 to 55 years
- If female, not pregnant, post-partum or breast feeding
- Have no significant medical or psychological history
- Not currently practicing CBT or have completed CBT treatment in the last 2 years
Some details:
- Participation involves a screening, online questionnaires, a before and after CBT brain MRI visit with a blood and stool sample and 8 weeks of internet guided CBT
Compensation:
- Men may earn up to $430
- Women may earn up to $480
- Everyone will receive a digital image of their brain
For more information: Email [email protected] or call 310-206-1719
Sex related differences in the effect of cognitive behavioral therapy (CBT) on emotional arousal and salience circuits and the role of the gut microbiome Project 3 Protocol ID: IRB#20-001118 UCLA IRB Approved Approval Date: 1/22/2021 Committee: Medical IRB 3
Looking for a non-drug alternative to reduce your IBS-related pain?
IB-Stim is a non-invasive device that works by sending subtle electrical impulses into cranial nerve branches in the ear. This stimulation then targets brain regions involved in processing pain. The IB-Stim has already been FDA approved for treating functional abdominal pain associated with IBS in children but not FDA approved in adults.
Participants must be:
- 18-60 years of age
- Diagnosed with IBS
- Not pregnant or breastfeeding
- Have no significant neurological or psychological medical history
Participation consists of :
- 4 visits over 1 month plus follow-up online questionnaires
- Each visit: New IB-STIM device placement
- Device work 5 days a week for 4 weeks
Compensation:
- Earn up to $175 for completing all visits
- Free parking
To learn more about participating in this study, please contact Dr. Adrienne Lenhart at [email protected]
This study is conducted by Lin Chang, MD, co-director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience.
Protocol ID: IRB#19-001796 UCLA IRB Approval Date: 7/8/2021 Through: 5/11/2023 Committee: Medical IRB