Gupta Lab

Researching the bidirectional interactions between the brain and the gut in shaping health and disease

Illustration of brain and gut
Dr. Arpana Gupta seated by monitors

About Us

Dr. Gupta’s research aims to bring a systems biology-based, comprehensive understanding of the pathophysiology underlying human obesity and the cluster of obesity-related conditions known as metabolic syndrome.

Sex and Race Differences

One barrier to progress in developing effective treatments for obesity may be the inconsistent consideration of sex and race differences in the underlying mechanisms.

Illustration of various racial profile silhouettes
Little boy crying

Environmental Influences

Psychosocial, cultural and environmental challenges, such as adverse childhood experiences, acculturation, neighborhood safety, family environment, and socioeconomic status heighten stress-related biological and behavioral pathways that increase the vulnerability to disease-promoting behaviors.