Hepatology Group
- Steven-Huy B. Han, MD (Principal)
- Gina Choi, MD
- Francisco Durazo, MD
- Mohamed El Kabany, MD
- Sammy Saab, MD, MPH
- Myron Tong, MD PhD
Funding
Current Research Projects
- NIH-funded DILIN (Drug-Induced Liver Injury Network)
- NIH-funded HBRN (Hepatitis B Research Network)
- NASH clinical trials
- alcoholic hepatitis clinical trial
- hepatitis B clinical trials
Future Research Directions
- Hepatitis B translational work
- NASH studies
- HCC studies
Current GI Research Fellows
- Kelvin Nguyen, MD
- Jennifer Phan, MD
Sammy Saab, MD, MPH - Individual Research
Funding
Current Research Projects
- NIH-elimination of hepatitis C from post-transplant community
- Long term outcomes of liver transplant recipients cured of hepatitis C
- Decision analysis mode on hepatitis C screening
- Risk of cardiovascular events with primary biliary cholangitis
- Association of sarcopenia and liver disease severity
- Risk of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis
- Metabolic complications in Latino patients with non-alcoholic steatohepatitis
- Telemedicine: effectiveness and patient satisfaction
Future Research Directions
- Liver transplantatio
- Cirrhosis
- Chronic hepatitis C
Key Publications (Partial List Including Only 2017)
- Younossi ZM, Park H, Dieterich D, Saab S, Ahmed A, Gordon SC. The Value of Cure Associated with Treating Treatment-naive Chronic Hepatitis C Genotype 1: Are the New All Oral Regimens Good Value to Society? Liver Int. 2017;37:662-668.
- Younossi ZM, Gordon SC, Ahmed A, Dieterich D, Saab S, Beckerman R. Treating Medicaid Patients with Hepatitis C: Clinical and Economic Impact. A J Managed Care. 2017;23:294-299.
- Nguyen K, Jimenez M, Moghadam N, Wu C, Farid A, Grotts J, Elashoff D, Choi G, Durazo FA, El-Kabany MM, Han SHB, Saab S. Decrease of Alpha-Fetoprotein in Patients with Cirrhosis Treated with Direct Acting Agents. Journal of Clinical and Translational Hepatology 2017;5:43-49.
- Patel AA, Walling AM, May FP, Saab S, Wenger N. Palliative Care and Healthcare Utilization for Patients with End-Stage Liver Disease at the End of Life. Clin Gastroenterol Hepatol. 2017 (in press).
- Lin TY, Shekar AO, Li N, Yeh MW, Saab S, Wilson M, Leung AM Incidence of Abnormal Liver Biochemical Tests in Hyperthyroidism Clin Endocrinol (Oxf). 2017; 86(5):755-759.
- Saab S, Viramontes, MR, Chalifoux SL, Craw CJ, Ramirez SD, Bau SN, Arevalo DG, Saab EG, Saab CM, Craw CS, Estafanous A, Messiah R, Messiah W, El Kabany M. Hepatitis C Virus Prevalence in Egyptian-Americans in Southern California. J Clin Gastroenterol 2017 (in press)
- Ahmed A, Gonzalez SA, Cholankeril G, Perumpail RB, McGinnis J, Saab S, Beckerman R, Younossi ZM. Treatment of Patients Waitlisted for Liver Transplant with an All-Oral DAAs is a Cost-Effective Treatment Strategy in the United States. Hepatology 2017;66(1):46-56.
- Younossi Z, Gordon SC, Ahmed A, Dieterich D, Saab S, Beckerman R. Treating Medicaid patients with hepatitis C: clinical and economic impact. Am J Manag Care. 2017;23:107-112.
- Saab S, Rheem J, Jimenez MA, Fong TM, Mai MM, Kachardoorian CA, Esmilzadeh NL, Bau SN, Kang S, Ramirez SD, Grotts, Choi G, Durazo FA, El-Kabany MM, Han SHB, Busuttil RW. Effectiveness of Ledipasvir/Sofosbuvir with/without Ribavirin in Liver Transplant Recipients with Hepatitis C. J Clin Transl Hepatol 2017;5(2):101-108.
- Saab S, Phan J, Jimenez M, Grotts J, Walters L, Hathaway K, Patel K, Lankarani A, Herman M, Holloman D, Nieto J. Endoscopic Ultrasound Liver Biopsies Accurately Predict the Presence of Fibrosis in Patients with Fatty Liver. Clinical Gastroenterology and Hepatology 2017 (in press).
- Elrazek A, Saab S, Foad M, Elgohary EA, Sallam MM, Nawara A, Ismael A, et al. Ongoing transmission of HCV: Should cesarean section be justified? Data mining discovery. J Transl Int Med. 2017;5:27-33.
- Stepanova M, Clement S, Wong R, Saab S, Ahmed A, Younossi ZM. Patients with Diabetes and Chronic Liver Disease are at Increased Risk for Overall Mortality: A Population Study from the United States. Clinical Diabetes 2017;35: 79-83.
- Aby E, Jimenez MA, Grotts JF, Agopian V French SW, Busuttil RW, Saab S. Diminishing Role of Liver Biopsy for Hepatitis C in Liver Transplant Recipients. J Clin Transl Hepatol 2017 (in press).
- Tavakoli H, Robinson A, Liu B, Bhuket T, Younossi Z, Saab S, Ahmed A, Wong RJ. Cirrhosis Patients with Nonalcoholic Steatohepatitis Are Significantly Less Likely to Receive Surveillance for Hepatocellular Carcinoma. Dig Dis Sci. 2017 (in press)
- Nieto J, Khaleel H, Challita Y, Jimenez M, Baron TH, Walters L, Hathaway K, Patel K, Lankarani A, Herman M, Holloman, D, Saab S. Endoscopic Ultrasound guided Fine Needle Core Liver Biopsy using a Novel 19 Gauge Needle with Modified One Pass One Actuation Wet Suction Technique. Gastrointestinal Endoscopy. 2017 (in press).
- Castrejón M, Chew KW, Javanbakht M, Humphries R, Saab S, Klausner JD. Implementation of a Large System-Wide Hepatitis C Virus Screening and Linkage to Care Program for Baby Boomers. Open Forum Infect Dis. 2017;4(3):ofx109. doi: 10.1093/ofid/ofx109.
Past GI Research Fellows
- Tyralee Goo, MD (2014-15)
- Victoria Sheen, MD (2014-15)
- Gina Choi, MD (2013-14)
- Justin Reynolds, MD (2012-13)
- Vivian Ng, MD (2012-13)
- Jennifer Tan, MD (2007-09)
- Lenna Martyak, MD (2007-08)
- Carmen Landaverde, MD (2007-09)
- Andrew Kim, MD (2006-07)
- Jose Nieto, DO (2004-06)
- Shiobhan Weston, MD (2002-03)
Current GI Research Fellows
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