Preferred Name: Dan Dumesic
Daniel Dumesic, MD is Professor of Reproductive Endocrinology and Infertility at the University of California, Los Angeles. Dr. Dumesic completed his residency in Obstetrics and Gynecology and fellowship in Reproductive Endocrinology and Infertility at the University of California San Francisco. His clinical and research interests include female infertility, in vitro fertilization (IVF) and polycystic ovary syndrome (PCOS). Certified by the American Board of Obstetrics and Gynecology, Dr. Dumesic is a leader in several internationally-recognized organizations and has served on several NIH research study sections and committees. He has received innumerable awards, including the Mayo Award for Excellence in Leadership, and is an eight-time recipient of the "Star Award" for more than 10 years of contributions to research for the American Society for Reproductive Medicine. With over 35 years of experience in human studies, he has served as Principal Investigator for several NIH-funded and university-awarded projects regarding mechanistic and clinical aspects of female reproductive disorders and has published over 200 papers in the field of reproductive endocrinology. Dr. Dumesic has been named "Top Doctor" in Southern California Top Doctors.
Medical Board Certifications
- Polycystic Ovary Syndrome (PCOS)
- Oocyte development and assisted reproductive techniques (ART) Nonhuman primate models of PCOS
- Developmental programming of adult diseases
- Dumesic DA, Hoyos LR, Chazenbalk GD, Naik R, Padmanabhan V, Abbott DH. Mechanisms of Intergenerational Transmission of Polycystic Ovary Syndrome. Reproduction 2020;159(1):R1-R13. PMID 31376813 PMC6989388
- Dumesic DA, Abbott DH, Sanchita S, Chazenbalk GD. Endocrine-Metabolic Dysfunction in Polycystic Ovary Syndrome: an Evolutionary Perspective. Curr Opin Endocr Metab Res 2020;12:41-48. PMID32363240 PMC7194185
- Hoyos LR, Putra M, Armstrong AA, Cheng CY, Riesenberg C, Schooler TA, Dumesic D. Measures of patient dissatisfaction with health care in polycystic ovary syndrome: retrospective analysis. J Med Internet Res 2020;22(4):e16541. doi: 10.2196/16541. PubMed PMID: 32314967 PMCID7201322
- Dumesic DA, Wood JR, Abbott DH, Strauss III, JF. A Primate Perspective on Oocytes and Transgenerational PCOS. Reprod Biomed Online 2020;40(6):765-767 PMID: 32312513.
- Stener-Victorin E, Padmanabhan P, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA, Abbott DH. Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocr Rev. 2020;41:538-576. PMID: 32310267
- Abbott DH, Levine JE, Dumesic A. Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome? Endocrinology 2020 Aug 1;161(8); doi: 10.1210/endocr/bqaa095. PMID 32530028.
- Puttabyatappa M, Dou J, Guo X, Dumesic D, Bakulski KM, Padmanabhan V. Developmental Programming: Granulosa and Theca Cell-Specific Transcriptional Regulation by Prenatal Testosterone in Sheep. Endocrinology 2020;161(8);1-17. doi: 10.1210/endocr/bqaa094. PMID 32516392.
- Hoyos LR, Visser JA, Mcluskey A, Chazenbalk GD, Grogan TR, Dumesic DA. Loss of anti-mullerian hormone (AMH) immunoreactivity due to a homozygous AMH gene mutation rs10417628 in a woman with classical polycystic ovary syndrome (PCOS). Human Reprod. 2020 Oct 1;35(10):2294-2302. doi: 10.1093/humrep/deaa199 PMID 32918081
- Leung KL, Sanchita S, Pham CT, Davis BA, Okhovat M, Ding X, Dumesic P, Grogan TR, Williams KJ, Morselli M, Ma F, Carbone L, Li X, Pellegrini M, Dumesic D, Chazenbalk GD. Dynamic Changes in Chromatin Accessibility, Altered Adipogenic Gene Expression, and Total vs De Novo Fatty Acid Synthesis in Subcutaneous Adipose Stem Cells of Normal-Weight Polycystic Ovary Syndrome (PCOS) Women During Adipogenesis: Evidence of Cellular Programming. Clin Epigenetics. 2020 Nov 23;12(1). doi: 10.1186/s13148-020-00970-x. PMID33228780: PMC7686698
- Dumesic DA, Tulberg A, Leung KL, Fisch SC, Grogan TR, Abbott DH, Naik R, Chazenbalk GD. Accelerated subcutaneous abdominal stem cell adipogenesis predicts insulin sensitivity in normal-weight women with polycystic ovary syndrome. Fertil Steril. 2020 Dec 16:S0015-0282(20)32511-5. doi: 10.1016/j.fertnstert.2020.10.003. Epub ahead of print. PMID: 33341231.
- Top Doctors, Los Angeles Magazine, 2021
- Mayo Award for Excellence in Leadership
- Ranked within top 2% of all scientists by Stanford University, 2020
- Eight-time recipient of the “Star Award” for more than 10 years of contributions to research for the American Society for Reproductive Medicine
- “Adipose Insulin Resistance in Normal-Weight Women with Polycystic Ovary Syndrome” one of the top 10% of articles published in the journal in 2018-2019.