Michael A. Teitell, MD, PhD

Michael A. Teitell, MD, PhD

  • Pediatric Anatomic Pathology


Michael Teitell received B.S. and M.S. degrees from the UCLA College Honors Program as a Departmental Scholar in Chemistry and Biochemistry in 1985. He earned combined M.D. and Ph.D. degrees in the UCLA Medical Scientist Training Program in 1993. His graduate and early post-doctoral studies were with Dr. Mitchell Kronenberg at UCLA in Molecular and Cellular Immunology. Dr. Teitell was a Resident and Clinical Instructor in Anatomic Pathology at Brigham and Women's Hospital and Harvard Medical School from 1993-1995. During this time he was a Research Associate with Dr. Richard Blumberg. From 1995-1997, Dr. Teitell was a Resident in Clinical Pathology at UCSF and a post-doctoral researcher with Dr. Joe Gray. From 1997-1999, he held a joint appointment at Children's Hospital of Los Angeles as a Pediatric Pathology Fellow and at UCLA as a Clinical Instructor in Pathology. He became an Assistant Professor in the UCLA Department of Pathology and Laboratory Medicine in 1999. He was jointly appointed in the UCLA Department of Pediatrics in 2001 and was promoted to Associate Professor with tenure in 2004. He currently serves as Chief of the Division of Pediatric and Neonatal Pathology, with board certification in anatomic, clinical and pediatric pathology.

Dr. Teitell has received several important honors and awards. Among these are the David Paul Kane Scholar Award of the Jonsson Cancer Center Foundation (2000-2001), the Lymphoma Research Foundation Junior Faculty Award (2001-2002), the FOCIS/Millenium Pharmaceuticals Young Investigator Award in Genomics Research (2001-2002), a Scholar Award from the Leukemia and Lymphoma Society (2003-2008), election to the American Society of Clinical Investigators (2004) and a Margaret E. Early Medical Research Trust Award (2005).

Education and Training

  • 1981-1985 UCLA, BS, MS - Chemistry and Biochemistry
  • 1985-1993 UCLA, MD, PhD - Molecular Immunology and Medicine

Research, Professional Experience and Professional Positions

  • 1991-1993 Post-doctoral Fellow, Microbiology and Immunology, UCLA
  • 1993-1995 Clinical Instructor and Resident, Anatomic Pathology, Brigham and Women's Hospital
  • 1994-1995 Research Associate, Medicine, Harvard Medical School
  • 1995-1997 Resident, Clinical Pathology, and Post-Doctoral Fellow, UCSF
  • 1997-1999 Fellow, Pediatric Pathology, Children's Hospital, Los Angeles
  • 1999-2004 Assistant Professor, Departments of Pathology and Pediatrics, UCLA
  • 2004-2008 Associate Professor, Departments of Pathology and Pediatrics, UCLA
  • 2008-present Professor, Departments of Pathology and Pediatrics, UCLA
  • 2014-present NCAA Faculty Athletics Representative, Intercollegiate Athletics, UCLA
  • 2017-present Director, Jonsson Comprehensive Cancer Center, UCLA
  • 2017-present President, Jonsson Cancer Center Foundation, UCLA
  • 2017-present Director, Cancer Research Theme, David Geffen School of Medicine, UCLA

Professional Activities

  • 1995-present American Association of Immunologists, Abul Abbas (sponsor)
  • 1999-present Member of the Molecular Biology Institute, UCLA
  • 1999-present Member of the Jonsson Comprehensive Cancer Center, UCLA
  • 2002-present American Society for Biochem and Molec Biology, Joan Conaway (sponsor)
  • 2003-present Medical Scientist Training Program, Executive Committee, UCLA
  • 2004-present American Association for Cancer Research, Richard Gatti (sponsor)
  • 2004-present NIH, Cancer Genetics Study Section Member
  • 2005-present Member, California NanoSystems Institute (CNSI)
  • 2005-present Member, Broad Center for Stem Cell Research (ISCBM), UCLA
  • 2006-present Member, Epigenetics Society
  • 2006-present American Society for Microbiology
  • 2006-present Section Editor, Laboratory Investigation
  • 2006-present Editorial Board, Nanomedicine
  • 2006-present Consulting Editor, Editorial Board, Pediatric Research
  • 2007-present Member, Biophysical Society, Robert Callender (sponsor)
  • 2007 Judge, College Board, Siemens Comp. in Math, Science & Technology, National Finals, NYU
  • 2008-2009 Chair, Intercollegiate Athletics Committee, UCLA
  • 2008 Chair, California Cancer Research Coordinating Committee
  • 2008 Chair, Oncogenic & Tumor Suppressor Pathways, AACR Annual Meeting




Medical Board Certifications

Pathology-Pediatric, American Board of Pathology, 2001
Pathology-Anatomic/Pathology-Clinical, American Board of Pathology, 1997


Pediatric Pathology, Children's Hospital of Los Angeles, 1999


Pathology & Laboratory Med., UC San Francisco School of Medicine, 1997
Pathology & Laboratory Med., Brigham and Women's Hospital, 1995


Pathology & Laboratory Med., Brigham and Women's Hospital, 1994


MD, UCLA School of Medicine, 1993
PhD, UCLA School of Medicine, 1991


  • 2017 Elected to Association of American Physicians (AAP)
  • 2012 - present: Lya and Harrison Latta Endowed Chair in Pathology, 2012 - present
  • 2008 Stohlman Scholar, Leukemia and Lymphoma Society
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Hospital Affiliations

Ronald Reagan UCLA Medical Center



Dr. Michael Teitell's lab is interested in molecular mechanisms of malignant transformation, with an emphasis on germinal center derived B-cell lymphomas. A screen that compared gene expression profiles from B-cell lymphomas in immune deficient versus immune competent settings identified TCL1 as a dysregulated oncogene in a large number of B-cell leukemias and lymphomas. Generation of a TCL1 transgenic mouse, in which TCL1 expression was maintained throughout B- and T-cell development, lead to one of the first genetic models for germinal center B-cell lymphomas and less frequently B- and T-cell chronic lymphocytic leukemias.

Studies in this model and in comparable human tumor samples lead to the elucidation of key aspects of TCL1-driven lymphomagenesis, including companion genetic and epigenetic alterations required for malignant transformation, affected signal transduction pathways, and a mechanism for abnormal avoidance of cell death. Tcl1 was shown in a broad screen by others to be the only verified oncogene that regulates stem cell self-renewal, providing a potential molecular link between so-called cancer stem cells and B-cell lymphoma that our lab is pursuing in studies of stem cells.

Since TCL1 dysregulation is the key for its tumorigenic action, studies on the mechanism of its expression have lead to discovery of a novel gene regulatory program for germinal center B-cells that requires signaling to the transcriptional co-repressor TORC2/CRTC2. This signaling links DNA damage repair sensing, such as occurs during antibody maturation steps in germinal center B-cells, to a major metabolism pathway that controls glucose homeostasis and cell respiration. One current goal is to understand the complex interrelationship between DNA damage, gene regulation, and control of cell metabolism uncovered by this work and to identify key components in this network as targets for therapeutic intervention.


  • Aetna
  • Anthem Blue Cross
  • Blue Shield of California
  • Centivo
  • Cigna
  • First Health
  • Health Net of California
  • Interplan (part of HealthSmart)
  • L.A. Care
  • MultiPlan
  • UFCM Health System
  • Prime Health Services
  • Private Healthcare Systems (PHCS)
  • UnitedHealthcare

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  • 2017 Elected to Association of American Physicians (AAP)
  • 2012 - present: Lya and Harrison Latta Endowed Chair in Pathology, 2012 - present
  • 2008 Stohlman Scholar, Leukemia and Lymphoma Society
  • 2005 Margaret E. Early Medical Research Trust Award
  • 2004 Elliot Osserman Award (for service in support of cancer research), ICRF
  • 2004 Elected to American Society of Clinical Investigators (ASCI)
  • 2003-2008 Scholar Award, Leukemia and Lymphoma Society
  • 2001 FOCIS/Millenium Pharmaceuticals Award for Genomics Research
  • 2000 Lymphoma Research Foundation of America Junior Faculty Award
  • 1999 David Paul Kane Scholar, Jonsson Cancer Center Foundation
  • 1997-1999 Lymphoma Research Foundation of America Fellow
  • 1985 Phi Beta Kappa, Eta Chapter
  • 1984-1985 Departmental Scholar in Biochemistry, UCLA
  • 1981-1985 University College Honors Program, UCLA