Faculty Publications (M - Z)

Note: Publications listed are 2012-Present (updated quarterly). Please click on PubMed links for earlier publications.

M N O P Q R S T U V W X Y Z

Moatamed, Neda, MD

Pleural fluid metastases of salivary duct carcinoma: A case report and review of the literature. Huss J Md, Conrad R Md, Hirschowitz S Md, Moatamed N Md. Cytojournal. 2014 Feb 15;11:4. eCollection 2014.

Exclusion of the uniform tetraploid cells significantly improves specificity of the urine fish assay. Moatamed NA, Apple SK, Bennett CJ, Aronson WJ, Klisak I, Shirley BJ, Moatamed F. Diagn Cytopathol. 2013 Mar;41(3):218-25. doi: 10.1002/dc.21831. Epub 2011 Oct 11. View abstract here

In Papanicolaou smears, benign appearing endometrial cells bear no significance in predicting uterine endometrial adenocarcinomas. Moatamed NA, Le LT, Levin MR, Govind R, Apple SK. Diagn Cytopathol. 2013 Apr;41(4):335-41. doi: 10.1002/dc.21863. Epub 2011 Nov 18. View abstract here

ProEx C as an adjunct marker to improve cytological detection of urothelial carcinoma in urinary specimens. Moatamed NA, Rao JY, Alexanian S, Cobarrubias M, Levin M, Lu D, Apple SK. Cancer Cytopathol. 2013 Jan 30. doi: 10.1002/cncy.21264. View abstract here

High concordance between HercepTest immunohistochemistry and ERBB2 fluorescence in situ hybridization before and after implementation of American Society of Clinical Oncology/College of American Pathology 2007 guidelines. Vergara-Lluri ME, Moatamed NA, Hong E, Apple SK. Mod Pathol. 2012 Oct;25(10):1326-32. doi: 10.1038/modpathol.2012.93. Epub 2012 Jun 15. View abstract here

Primary effusion lymphoma involving the cerebrospinal fluid. Moatamed NA, Song SX, Apple SK, Said JW. Diagn Cytopathol. 2012 Jul;40(7):635-8. doi: 10.1002/dc.21653. Epub 2011 Mar 4. View abstract here

Genital rhabdomyoma of the urethra in an infant girl. Lu DY, Chang S, Cook H, Alizadeh Y, Karam AK, Moatamed NA, Dry SM. Hum Pathol. 2012 Apr;43(4):597-600. doi: 10.1016/j.humpath.2011.06.012. Epub 2011 Oct 10. View abstract here

Pleomorphic adenoma of the vulva, clinical reminder of a rare occurrence. Su A, Apple SK, Moatamed NA. Rare Tumors. 2012 Jan 2;4(1):e16. doi: 10.4081/rt.2012.e16. Epub 2012 Mar 8. View abstract here

Paraganglioma with unusual presentation in parotid gland: A diagnostic dilemma in fine needle aspiration. Vora AA, Lai CK, Rao JY, Apple SK, Moatamed NA. Cytojournal. 2012;9:26. doi: 10.4103/1742-6413.105119. Epub 2012 Dec 27. View abstract here

PubMed: Neda Moatamed


Naini, Bita V, MD

Appropriate use of special stains for identifying Helicobacter pylori: Recommendations from the Rodger C. Haggitt Gastrointestinal Pathology Society. Batts KP, Ketover S, Kakar S, Krasinskas AM, Mitchell KA, Wilcox R, Westerhoff M, Rank J, Gibson J, Mattia AR, Cummings OW, Davison JM, Naini BV, Dry SM, Yantiss RK; Rodger C Haggitt Gastrointestinal Pathology Society. Am J Surg Pathol. 2013 Nov;37(11):e12-22. doi: 10.1097/PAS.0000000000000097. Review.

Advanced precancerous lesions (APL) in the colonic mucosa. Naini BV, Odze RD. Best Pract Res Clin Gastroenterol. 2013 Apr;27(2):235-56. doi: 10.1016/j.bpg.2013.03.012. Review.

Chromophobe hepatocellular carcinoma with abrupt anaplasia: a proposal for a new subtype of hepatocellular carcinoma with unique morphological and molecular features. Wood LD, Heaphy CM, Daniel HD, Naini BV, Lassman CR, Arroyo MR, Kamel IR, Cosgrove DP, Boitnott JK, Meeker AK, Torbenson MS. Mod Pathol. 2013 May 3. doi: 10.1038/modpathol.2013.68. View abstract here

Polypectomy is Adequate Treatment for Adenoma-like Dysplastic Lesions (DALMs) in Crohn's Disease. Quinn AM, Farraye FA, Naini BV, Cerda S, Coukos J, Li Y, Khor T, Odze RD. Inflamm Bowel Dis. 2013 Apr 4. View abstract here

Assessment of hepatic steatosis by transplant surgeon and expert pathologist: A prospective, double-blind evaluation of 201 donor livers. Yersiz H, Lee C, Kaldas FM, Hong JC, Rana A, Schnickel GT, Wertheim JA, Zarrinpar A, Agopian VG, Gornbein J, Naini BV, Lassman CR, Busuttil RW, Petrowsky H. Liver Transpl. 2013 Feb 13. doi: 10.1002/lt.23615. View abstract here

A histopathologic scoring system as a tool for standardized reporting of chronic (ileo)colitis and independent risk assessment for inflammatory bowel disease. Naini BV, Cortina G. Hum Pathol. 2012 Dec;43(12):2187-96. doi: 10.1016/j.humpath.2012.03.008. Epub 2012 Jun 14. View abstract here

Total parenteral nutrition therapy and liver injury: a histopathologic study with clinical correlation. Naini BV, Lassman CR. Hum Pathol. 2012 Jun;43(6):826-33. doi: 10.1016/j.humpath.2011.07.008. Epub 2011 Nov 9. View abstract here

Diagnosis of dysplasia in upper gastro-intestinal tract biopsies through digital microscopy. Gui D, Cortina G, Naini B, Hart S, Gerney G, Dawson D, Dry S. J Pathol Inform. 2012;3:27. Epub 2012 Aug 25. View abstract here

PubMed: Bita V Naini


Nelson, Scott, MD

Costal osteochondroma spicule associated with pleural effusion. Chen J, Nelson S, Tzung B, Applebaum H, Deugarte DA. Pediatr Surg Int. 2013 May 8. View abstract here

Image-guided Percutaneous Core Needle Biopsy of Musculoskeletal Tumors in Children. Mitton B, Seeger LL, Eckardt MA, Motamedi K, Eilber FC, Nelson SD, Eckardt JJ, Federman N. J Pediatr Hematol Oncol. 2013 Apr 11. View abstract here

Long-term results (>25 years) of a randomized, prospective clinical trial evaluating chemotherapy in patients with high-grade, operable osteosarcoma. Bernthal NM, Federman N, Eilber FR, Nelson SD, Eckardt JJ, Eilber FC, Tap WD. Cancer. 2012 Dec 1;118(23):5888-93. doi: 10.1002/cncr.27651. Epub 2012 May 30. View abstract here

A Single-institution Retrospective Cases Series of Childhood Undifferentiated Embryonal Liver Sarcoma (UELS): Success of Combined Therapy and the Use of Orthotopic Liver Transplant. Plant AS, Busuttil RW, Rana A, Nelson SD, Auerbach M, Federman NC. J Pediatr Hematol Oncol. 2012 Nov 6. View abstract here

Relevance of compartmental anatomic guidelines for biopsy of musculoskeletal tumors: retrospective review of 363 biopsies over a 6-year period. UyBico SJ, Motamedi K, Omura MC, Nelson SD, Eilber FC, Eckardt J, Seeger LL. J Vasc Interv Radiol. 2012 Apr;23(4):511-18, 518.e1-2. doi: 10.1016/j.jvir.2012.01.058. Epub 2012 Mar 3. View abstract here

Single-institution, multidisciplinary experience with surgical resection of primary chest wall sarcomas. Kachroo P, Pak PS, Sandha HS, Lee C, Elashoff D, Nelson SD, Chmielowski B, Selch MT, Cameron RB, Holmes EC, Eilber FC, Lee JM. J Thorac Oncol. 2012 Mar;7(3):552-8. doi: 10.1097/JTO.0b013e31824176df. View abstract here

Chest wall sarcomas are accurately diagnosed by image-guided core needle biopsy. Kachroo P, Pak PS, Sandha HS, Nelson SD, Seeger LL, Cameron RB, Eilber FC, Lee JM. J Thorac Oncol. 2012 Jan;7(1):151-6. doi: 10.1097/JTO.0b013e3182307f4c. View abstract here

PubMed: Scott Nelson


Nelson, Stanley, MD

Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome. Klein S, Lee H, Ghahremani S, Kempert P, Ischander M, Teitell MA, Nelson SF, Martinez-Agosto JA. J Med Genet. 2014 May;51(5):294-302. doi: 10.1136/jmedgenet-2013-101943. Epub 2014 Mar 27.

Rich annotation of DNA sequencing variants by leveraging the Ensembl Variant Effect Predictor with plugins. Yourshaw M, Taylor SP, Rao AR, Martín MG, Nelson SF. Brief Bioinform. 2014 Mar 12.

Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation. Lee H, Lin MC, Kornblum HI, Papazian DM, Nelson SF. Hum Mol Genet. 2014 Feb 18.

Whole exome sequencing detects homozygosity for ABCA4 p.Arg602Trp missense mutation in a pediatric patient with rapidly progressive retinal dystrophy. Ortube MC, Strom SP, Nelson SF, Nusinowitz S, Martinez A, Gorin MB. BMC Med Genet. 2014 Jan 20;15:11. doi: 10.1186/1471-2350-15-11.

Assessing the necessity of confirmatory testing for exome-sequencing results in a clinical molecular diagnostic laboratory. Strom SP, Lee H, Das K, Vilain E, Nelson SF, Grody WW, Deignan JL. Genet Med. 2014 Jan 9. doi: 10.1038/gim.2013.183. [Epub ahead of print]

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, Reed R, Nelson SF, Cloughesy TF, James CD, Rao PN, Kornblum HI, Heath JR, Cavenee WK, Furnari FB, Mischel PS. Science. 2014 Jan 3;343(6166):72-6. doi: 10.1126/science.1241328. Epub 2013 Dec 5.

X chromosome exome sequencing reveals a novel ALG13 mutation in a nonsyndromic intellectual disability family with multiple affected male siblings. Bissar-Tadmouri N, Donahue WL, Al-Gazali L, Nelson SF, Bayrak-Toydemir P, Kantarci S. Am J Med Genet A. 2014 Jan;164A(1):164-9.

Genome sequencing highlights the dynamic early history of dogs. Freedman AH, Gronau I, Schweizer RM, Ortega-Del Vecchyo D, Han E, Silva PM, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Beale H, Ramirez O, Hormozdiari F, Alkan C, Vilà C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Ostrander EA, Marques-Bonet T, Wayne RK, Novembre J. PLoS Genet. 2014 Jan;10(1):e1004016. doi: 10.1371/journal.pgen.1004016. Epub 2014 Jan 16.

Exome sequencing finds a novel PCSK1 mutation in a child with generalized malabsorptive diarrhea and diabetes insipidus. Yourshaw M, Solorzano-Vargas RS, Pickett LA, Lindberg I, Wang J, Cortina G, Pawlikowska-Haddal A, Baron H, Venick RS, Nelson SF, Martín MG. J Pediatr Gastroenterol Nutr. 2013 Dec;57(6):759-67. doi: 10.1097/MPG.0b013e3182a8ae6c.

SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Yoshida-Moriguchi T, Willer T, Anderson ME, Venzke D, Whyte T, Muntoni F, Lee H, Nelson SF, Yu L, Campbell KP. Science. 2013 Aug 23;341(6148):896-9. doi: 10.1126/science.1239951. Epub 2013 Aug 8.

Therapeutic Potential of HSP90 Inhibition for Neurofibromatosis Type 2. Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. Clin Cancer Res. 2013 Jun 21. View abstract here

Whole exome sequencing of pediatric gastric adenocarcinoma reveals an atypical presentation of Li-Fraumeni syndrome. Chang VY, Federman N, Martinez-Agosto J, Tatishchev SF, Nelson SF. Pediatr Blood Cancer. 2013 Apr;60(4):570-4. doi: 10.1002/pbc.24316. Epub 2012 Sep 26. View abstract here

Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia. Chang VY, Basso G, Sakamoto KM, Nelson SF. BMC Cancer. 2013 Feb 4;13:55. doi: 10.1186/1471-2407-13-55. View abstract here

Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy. Kendall GC, Mokhonova EI, Moran M, Sejbuk NE, Wang DW, Silva O, Wang RT, Martinez L, Lu QL, Damoiseaux R, Spencer MJ, Nelson SF, Miceli MC. Sci Transl Med. 2012 Dec 12;4(164):164ra160. doi: 10.1126/scitranslmed.3005054. View abstract here

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas. Chou AP, Chowdhury R, Li S, Chen W, Kim AJ, Piccioni DE, Selfridge JM, Mody RR, Chang S, Lalezari S, Lin J, Sanchez DE, Wilson RW, Garrett MC, Harry B, Mottahedeh J, Nghiemphu PL, Kornblum HI, Mischel PS, Prins RM, Yong WH, Cloughesy T, Nelson SF, Liau LM, Lai A. J Natl Cancer Inst. 2012 Oct 3;104(19):1458-69. doi: 10.1093/jnci/djs357. Epub 2012 Sep 3. View abstract here

Molecular diagnosis of putative Stargardt Disease probands by exome sequencing. Strom SP, Gao YQ, Martinez A, Ortube C, Chen Z, Nelson SF, Nusinowitz S, Farber DB, Gorin MB. BMC Med Genet. 2012 Aug 3;13:67. View abstract here

Identification of allele-specific alternative mRNA processing via transcriptome sequencing. Li G, Bahn JH, Lee JH, Peng G, Chen Z, Nelson SF, Xiao X. vNucleic Acids Res. 2012 Jul;40(13):e104. doi: 10.1093/nar/gks280. Epub 2012 Mar 29. View abstract here

High throughput screening for compounds that alter muscle cell glycosylation identifies new role for N-glycans in regulating sarcolemmal protein abundance and laminin binding. Cabrera PV, Pang M, Marshall JL, Kung R, Nelson SF, Stalnaker SH, Wells L, Crosbie-Watson RH, Baum LG. J Biol Chem. 2012 Jun 29;287(27):22759-70. doi: 10.1074/jbc.M111.334581. Epub 2012 May 8. View abstract here

Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Arboleda VA, Lee H, Parnaik R, Fleming A, Banerjee A, Ferraz-de-Souza B, Délot EC, Rodriguez-Fernandez IA, Braslavsky D, Bergadá I, Dell'Angelica EC, Nelson SF, Martinez-Agosto JA, Achermann JC, Vilain E. Nat Genet. 2012 May 27;44(7):788-92. doi: 10.1038/ng.2275. View abstract here

Mutations in the RNA exosome component gene EXOSC3 cause pontocerebellar hypoplasia and spinal motor neuron degeneration. Wan J, Yourshaw M, Mamsa H, Rudnik-Schöneborn S, Menezes MP, Hong JE, Leong DW, Senderek J, Salman MS, Chitayat D, Seeman P, von Moers A, Graul-Neumann L, Kornberg AJ, Castro-Gago M, Sobrido MJ, Sanefuji M, Shieh PB, Salamon N, Kim RC, Vinters HV, Chen Z, Zerres K, Ryan MM, Nelson SF, Jen JC. Nat Genet. 2012 Apr 29;44(6):704-8. doi: 10.1038/ng.2254. View abstract here

Exome sequencing identifies PDE4D mutations in acrodysostosis. Lee H, Graham JM Jr, Rimoin DL, Lachman RS, Krejci P, Tompson SW, Nelson SF, Krakow D, Cohn DH. Am J Hum Genet. 2012 Apr 6;90(4):746-51. doi: 10.1016/j.ajhg.2012.03.004. Epub 2012 Mar 29. View abstract here

Genome-wide association study of intelligence: additive effects of novel brain expressed genes. Loo SK, Shtir C, Doyle AE, Mick E, McGough JJ, McCracken J, Biederman J, Smalley SL, Cantor RM, Faraone SV, Nelson SF. J Am Acad Child Adolesc Psychiatry. 2012 Apr;51(4):432-440.e2. doi: 10.1016/j.jaac.2012.01.006. Epub 2012 Feb 28. View abstract here

Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance. Shi H, Moriceau G, Kong X, Lee MK, Lee H, Koya RC, Ng C, Chodon T, Scolyer RA, Dahlman KB, Sosman JA, Kefford RF, Long GV, Nelson SF, Ribas A, Lo RS. Nat Commun. 2012 Mar 6;3:724. doi: 10.1038/ncomms1727. View abstract here

PubMed: Stanley Nelson


Ostrzega, Nora, MD

Predictors of resolution of complex atypical hyperplasia or grade 1 endometrial adenocarcinoma in premenopausal women treated with progestin therapy. Penner KR, Dorigo O, Aoyama C, Ostrzega N, Balzer BL, Rao J, Walsh CS, Cass I, Holschneider CH. Gynecol Oncol. 2012 Mar;124(3):542-8. doi: 10.1016/j.ygyno.2011.11.004. Epub 2011 Nov 10. View abstract here

Lymphomatoid granulomatosis: a rare mimicker of vasculitis. Wu SM, Min Y, Ostrzega N, Clements PJ, Wong AL. J Rheumatol. 2005 Nov;32(11):2242-5. View abstract here

Histologic and immunohistochemical characteristics of neoplastic and nonneoplastic subgroups of atypical squamous lesions of the uterine cervix. Aoyama C, Liu P, Ostrzega N, Holschneider CH. Am J Clin Pathol. 2005 May;123(5):699-706. View abstract here

Lymphovascular and perineural invasion in the parametria: a prognostic factor for early-stage cervical cancer. Memarzadeh S, Natarajan S, Dandade DP, Ostrzega N, Saber PA, Busuttil A, Lentz SE, Berek JS. Obstet Gynecol. 2003 Sep;102(3):612-9. View abstract here

PubMed: Nora Ostrzega


Pasaniuc, Bogdan, PhD

IBD genetics: focus on (dys) regulation in immune cells and the epithelium. Kaser A, Pasaniuc B. Gastroenterology. 2014 Apr;146(4):896-9. doi: 10.1053/j.gastro.2014.02.023. Epub 2014 Feb 22. No abstract available.

Enhanced methods for local ancestry assignment in sequenced admixed individuals. Brown R, Pasaniuc B. PLoS Comput Biol. 2014 Apr 17;10(4):e1003555. doi: 10.1371/journal.pcbi.1003555. eCollection 2014 Apr.

Quantifying missing heritability at known GWAS loci. Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. PLoS Genet. 2013 Dec;9(12):e1003993. doi: 10.1371/journal.pgen.1003993. Epub 2013 Dec 26.

Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data. Yang WY, Hormozdiari F, Wang Z, He D, Pasaniuc B, Eskin E. Bioinformatics. 2013 Sep 15;29(18):2245-52. doi: 10.1093/bioinformatics/btt386. Epub 2013 Jul 3. View abstract here

Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, Gonzàlez Burchard E, Halperin E. Bioinformatics. 2013 Jun 1;29(11):1407-15. doi: 10.1093/bioinformatics/btt166. Epub 2013 Apr 9. View abstract here

PubMed: Bogdan Pasaniuc


Phelps, Michael, PhD

Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. Murphy JM, Armijo AL, Nomme J, Lee CH, Smith QA, Li Z, Campbell DO, Liao HI, Nathanson DA, Austin WR, Lee JT, Darvish R, Wei L, Wang J, Su Y, Damoiseaux R, Sadeghi S, Phelps ME, Herschman HR, Czernin J, Alexandrova AN, Jung ME, Lavie A, Radu CG. J Med Chem. 2013 Sep 12;56(17):6696-708. doi: 10.1021/jm400457y. Epub 2013 Aug 15. View abstract here

Plug-and-play modules for flexible radiosynthesis. Herman H, Flores G, Quinn K, Eddings M, Olma S, Moore MD, Ding H, Bobinski KP, Wang M, Williams D, Wiliams D, Shen CK, Phelps ME, van Dam RM. Appl Radiat Isot. 2013 Aug;78:113-24. doi: 10.1016/j.apradiso.2013.04.023. Epub 2013 Apr 25. View abstract here

Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. Austin WR, Armijo AL, Campbell DO, Singh AS, Hsieh T, Nathanson D, Herschman HR, Phelps ME, Witte ON, Czernin J, Radu CG. J Exp Med. 2012 Nov 19;209(12):2215-28. doi: 10.1084/jem.20121061. Epub 2012 Nov 12. View abstract here

18F-FDOPA and 18F-FLT positron emission tomography parametric response maps predict response in recurrent malignant gliomas treated with bevacizumab. Harris RJ, Cloughesy TF, Pope WB, Nghiemphu PL, Lai A, Zaw T, Czernin J, Phelps ME, Chen W, Ellingson BM. Neuro Oncol. 2012 Aug;14(8):1079-89. doi: 10.1093/neuonc/nos141. Epub 2012 Jun 18. View abstract here

18F-FDG-PET/CT Imaging as an early survival predictor in patients with primary high-grade soft tissue sarcomas undergoing neoadjuvant therapy. Herrmann K, Benz MR, Czernin J, Allen-Auerbach MS, Tap WD, Dry SM, Schuster T, Eckardt JJ, Phelps ME, Weber WA, Eilber FC. Clin Cancer Res. 2012 Apr 1;18(7):2024-31. doi: 10.1158/1078-0432.CCR-11-2139. Epub 2012 Feb 14. View abstract here

Impact of 3,4-dihydroxy-6-18F-fluoro-L-phenylalanine PET/CT on managing patients with brain tumors: the referring physician's perspective. Walter F, Cloughesy T, Walter MA, Lai A, Nghiemphu P, Wagle N, Fueger B, Satyamurthy N, Phelps ME, Czernin J. J Nucl Med. 2012 Mar;53(3):393-8. doi: 10.2967/jnumed.111.095711. Epub 2012 Feb 9. View abstract here

Micro-chemical synthesis of molecular probes on an electronic microfluidic device. Keng PY, Chen S, Ding H, Sadeghi S, Shah GJ, Dooraghi A, Phelps ME, Satyamurthy N, Chatziioannou AF, Kim CJ, van Dam RM. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):690-5. doi: 10.1073/pnas.1117566109. Epub 2011 Dec 30. View abstract here

3'-deoxy-3'-18F-fluorothymidine PET and MRI for early survival predictions in patients with recurrent malignant glioma treated with bevacizumab. Schwarzenberg J, Czernin J, Cloughesy TF, Ellingson BM, Pope WB, Geist C, Dahlbom M, Silverman DH, Satyamurthy N, Phelps ME, Chen W. J Nucl Med. 2012 Jan;53(1):29-36. doi: 10.2967/jnumed.111.092387. Epub 2011 Dec 12. View abstract here

PubMed: Michael Phelps


Pothoulakis, Charalabos, MD

Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. J Mol Neurosci. 2014 Jan;52(1):37-47. doi: 10.1007/s12031-013-0205-3. Epub 2014 Jan 7.

Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease. Steinhoff MS, von Mentzer B, Geppetti P, Pothoulakis C, Bunnett NW. Physiol Rev. 2014 Jan;94(1):265-301. doi: 10.1152/physrev.00031.2013. Review.

Silence Please!: siRNA approaches to tighten the intestinal barrier in vivo. Bakirtzi K, Hoffman JM, Pothoulakis C. Am J Pathol. 2013 Dec;183(6):1700-2. doi: 10.1016/j.ajpath.2013.10.001. Epub 2013 Oct 30.

MicroRNA-124 Regulates STAT3 Expression and Is Down-regulated in Colon Tissues of Pediatric Patients With Ulcerative Colitis. Koukos G, Polytarchou C, Kaplan JL, Morley-Fletcher A, Gras-Miralles B, Kokkotou E, Baril-Dore M, Pothoulakis C, Winter HS, Iliopoulos D. Gastroenterology. 2013 Oct;145(4):842-852.e2. doi: 10.1053/j.gastro.2013.07.001. Epub 2013 Jul 12. View abstract here

Identification of a Functional TPH1 Polymorphism Associated With Irritable Bowel Syndrome Bowel Habit Subtypes. Grasberger H, Chang L, Shih W, Presson AP, Sayuk GS, Newberry RD, Karagiannides I, Pothoulakis C, Mayer E, Merchant JL. Am J Gastroenterol. 2013 Sep 24. doi: 10.1038/ajg.2013.304. View abstract here

Human Monoclonal Antibodies against Clostridium difficile Toxins A and B Inhibit Inflammatory and Histologic Responses to the Toxins in Human Colon and Peripheral Blood Monocytes. Koon HW, Shih DQ, Hing TC, Yoo JH, Ho S, Chen X, Kelly CP, Targan SR, Pothoulakis C. Antimicrob Agents Chemother. 2013 Jul;57(7):3214-23. doi: 10.1128/AAC.02633-12. Epub 2013 Apr 29 View abstract here

Antimicrobial peptides and colitis. Ho S, Pothoulakis C, Koon HW. Curr Pharm Des. 2013;19(1):40-7. View abstract here

Differentiating functional roles of gene expression from immune and non-immune cells in mouse colitis by bone marrow transplantation. Koon HW, Ho S, Cheng M, Ichikawa R, Pothoulakis C. J Vis Exp. 2012 Oct 1;(68):e4208. doi: 10.3791/4208. View abstract here

Adipose tissue and inflammatory bowel disease pathogenesis. Fink C, Karagiannides I, Bakirtzi K, Pothoulakis C. Inflamm Bowel Dis. 2012 Aug;18(8):1550-7. doi: 10.1002/ibd.22893. Epub 2012 Mar 8. View abstract here

The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice. Hing TC, Ho S, Shih DQ, Ichikawa R, Cheng M, Chen J, Chen X, Law I, Najarian R, Kelly CP, Gallo RL, Targan SR, Pothoulakis C, Koon HW. Gut. 2012 Jul 3. View abstract here

Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by ß-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1. Law IK, Murphy JE, Bakirtzi K, Bunnett NW, Pothoulakis C. J Biol Chem. 2012 Apr 27;287(18):15066-75. doi: 10.1074/jbc.M111.327262. Epub 2012 Mar 13. View abstract here

The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer. Bugni JM, Rabadi LA, Jubbal K, Karagiannides I, Lawson G, Pothoulakis C. Int J Cancer. 2012 Apr 15;130(8):1798-805. doi: 10.1002/ijc.26208. Epub 2011 Nov 17. View abstract here

Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders. Kelesidis T, Pothoulakis C. Therap Adv Gastroenterol. 2012 Mar;5(2):111-25. doi: 10.1177/1756283X11428502. View abstract here

Serum and colonic mucosal immune markers in irritable bowel syndrome. Chang L, Adeyemo M, Karagiannides I, Videlock EJ, Bowe C, Shih W, Presson AP, Yuan PQ, Cortina G, Gong H, Singh S, Licudine A, Mayer M, Tache Y, Pothoulakis C, Mayer EA. Am J Gastroenterol. 2012 Feb;107(2):262-72. doi: 10.1038/ajg.2011.423. Epub 2011 Dec 13. Erratum in: Am J Gastroenterol. 2012 Mar;107(3):492. Karagiannidis, Iordanis [corrected to Karagiannides, Iordanis]. View abstract here

PubMed: Charalabos Pothouiakis


Pullarkat, Sheeja, MD

Acute myeloid leukemia with t(7;21)(p22;q22) and 5q deletion: a case report and literature review. Ji J, Loo E, Pullarkat S, Yang L, Tirado CA. Exp Hematol Oncol. 2014 Mar 19;3(1):8.

Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1. Pullarkat ST, Pullarkat V, Lagoo A, Brynes R, Weiss LM, Bedell V, Chen W, Huang Q, Gaal K, Weisenburger DD, Kim YS. Leuk Res. 2013 Sep 1. doi:pii: S0145-2126(13)00292-0. 10.1016/j.leukres.2013.08.010. View abstract here

Stem cell transplantation in primary myelofibrosis of childhood. Mitton B, Oliveira Sd, Pullarkat ST, Moore TB. J Pediatr Hematol Oncol. 2013 Apr;35(3):e120-2. doi: 10.1097/MPH.0b013e31828800cc. View abstract here

Epstein-Barr virus patterns in US Burkitt lymphoma tumors from the SEER residual tissue repository during 1979-2009. Mbulaiteye SM, Pullarkat ST, Nathwani BN, Weiss LM, Nagesh Rao, Emmanuel B, Lynch CF, Hernandez B, Neppalli V, Hawes D, Cockburn MG, Kim A, Williams M, Altekruse S, Bhatia K, Goodman MT, Cozen W. APMIS. 2013 Apr 23. doi: 10.1111/apm.12078. View abstract here

KSHV/HHV8-negative effusion-based lymphoma, a distinct entity associated with fluid overload states. Alexanian S, Said J, Lones M, Pullarkat ST. Am J Surg Pathol. 2013 Feb;37(2):241-9. doi: 10.1097/PAS.0b013e318267fabc. View abstract here

Risk of lymphoma in patients receiving antitumor necrosis factor therapy: a meta-analysis of published randomized controlled studies. Wong AK, Kerkoutian S, Said J, Rashidi H, Pullarkat ST. Clin Rheumatol. 2012 Apr;31(4):631-6. doi: 10.1007/s10067-011-1895-y. Epub 2011 Nov 18. View abstract here

Accelerated phase of Chediak-Higashi syndrome. Pullarkat ST. Blood. 2012 Jan 5;119(1):5. View abstract here

PubMed: Sheeja Pullarkat


Rao, Dinesh, MD, PhD

Since 2012:

Balasz AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D (2012). “Antibody-based protection against HIV infection by vectored immunoprophylaxis.” Nature, 481(7379):81-4.

Chaudhuri AA, So AY, Mehta A, Minisandram A, Sinha N, Jonsson VD, Rao DS, O'Connell RM, Baltimore D (2012). “Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A.” Proc Natl Acad Sci USA, 109(11):4233-8.

Hur EM, Patel SN, Shimizu S, Rao DS, Gnanapragasam PN, An DS, Yang L, Baltimore D (2012). “Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice.” Blood, 120(23):4571-82.

Pigazzi M, Manara E, Bresolin S, Tregnago C, Beghin A, Baron E, Giarin E, Cho EC, Masetti R, Rao DS, Sakamoto KM, Basso G (2013). “MiR-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation.” Hematologica, 98(4):602-10.

Zhao JL, Rao DS, O’Connell RM, Garcia-Flores Y, Baltimore D (2013). “MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice” eLife; May 21;2:e00537. doi: 10.7554/eLife.00537. Print 2013.

Balasz AB, Bloom JD, Hong CM, Rao DS, Baltimore D (2013). “Broad Protection Against Influenza by Vectored ImmunoProphylaxis”. Nature Biotechnology, 31(7):647-5. 2doi: 10.1038/nbt.2618. [Epub ahead of print].

Basak SK, Veena MS, Oh S, Lai C, Vangala S, Elashoff D, Fishbein MC, Sharma S, Rao NP, Rao D, Phan R, Srivatsan ES, Batra RK (2013). “The CD44(high) Tumorigenic Subsets in Lung Cancer Biospecimens Are Enriched for Low miR-34a Expression”. PLos One, 8(9):e73195.

Tirado CA, Shabsovich D, Denicola M, Rao D, Yang L, Garcia R, Rao N (2013). “A case of pediatric B-Lymphoblastic leukemia presenting with a t(9;12)(p24;q11.2) involving JAK2 and concomitant MLL rearrangement with apparent insertion at 6q27.” Biomark Res. 25(1): 31.

Balazs AB, Ouyang Y, Hong CM, Chen J, Nguyen SM, Rao DS, An DS, Baltimore D. (2014) “Vectored Immunoprophylaxis Protects Humanized Mice from Mucosal HIV Transmission”. Nature Medicine, 20(3):296-300.

Fang J, Barker B, Bolanos L, Liu X, Jerez A, Makishima H, Christie S, Chen X, Rao DS, Grimes HL, Komurov K, Weirauch MT, Cancelas JA, Maciejewski JP, Starczynowski DT. (2014) “Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network.

Cell Rep. 8(5):1328-38.

Hu R, Kagele DA, Huffaker TB, Runtsch MC, Alexander M, Blake E, Su W, Rao DS, Moeller T, Garden G, Round JL O’Connell RM. (2014)“MicroRNAs gauge T follicular helper cell accumulation during aging”. Immunity, 41(4): 605-619.

Fernando TR, Rodriguez-Malave NI, Waters EW, Yan W, Casero D, Pigazzi M, Basso G, Rao DS. “LincRNA expression discriminates cytogenetic subtypes in B-lymphoblastic leukemia and plays a functional role in leukemia cell survival”. Mol Cancer Research, 13(5):839-51 [Corresponding author]

Contreras JR , Palanichamy JK , Tran T , Fernando TR ,  Rodriguez-Malave NI, Arboleda VA, Casero D, and Rao DS (2015) “MicroRNA-146a modulates B-cell oncogenesis by targeting Egr1.” Oncotarget, 6: 11023-37. [Corresponding Author]

Rodríguez-Malavé NI, Fernando TR, Patel PC, Contreras JR, Palanichamy JK, Tran TM, Anguiano J, Davoren MJ, Alberti MO, Pioli KT, Sandoval S, Crooks GM, Rao DS (2015). "BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia".  Mol Cancer14(1):214. [Corresponding Author]

Palanichamy JK, Tran TM, Howard JM, Contreras JR, Fernando TR, Sterne-Weiler T, Katzman S, Taloue M, Yan, W, Basso G, Pigazzi M, Sanford JR, Rao DS (2016). “RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation”. Journal of Clinical Investigation, 126(4):1495-511. doi: 10.1172/JCI80046. Epub 2016 Mar 14. [Corresponding Author]

Wallace J, Hu R, Mosbruger TL, Dahlem TJ, Stephens WZ, Rao DS, Round JL, O’Connell RM (2016). “Genome-wide CRISPR-Cas9 screen identifies microRNAs that regulate myeloid leukemia cell growth”. PloS one. 2016; 11(4):e0153689.

King JK, Ung NM, Paing MH, Contreras JR, Alberti MO, Fernando TR, Zhang K, Pellegrini M, Rao DS (2017). “Refulation of marginal zone B-cell development by microRNA-146a”. Frontiers Immunol. 7: doi: 10.3389/fimmu.2016.00670. [Corresponding Author]

PubMed: Dinesh Rao


Rao, JianYu, MD

Longitudinal trends in prostate cancer incidence, mortality, and survival of patients from two Shanghai city districts: a retrospective population-based cohort study, 2000-2009. Hu Y, Zhao Q, Rao J, Deng H, Yuan H, Xu B. BMC Public Health. 2014 Apr 14;14(1):356.

The role of Rho GTPase in cell stiffness and cisplatin resistance in ovarian cancer cells. Sharma S, Santiskulvong C, Rao J, Gimzewski JK, Dorigo O. Integr Biol (Camb). 2014 Apr 10.

Prior High-Risk Human Papillomavirus Testing and Papanicolaou Test Results of 70 Invasive Cervical Carcinomas Diagnosed in 2012: Results of a Retrospective Multicenter Study. Zhao C, Li Z, Nayar R, Levi AW, Winkler BA, Moriarty AT, Barkan GA, Rao J, Miller F, Fan F, Zhou Z, Si Q, Fischer AH, Sturgis CD, Jing X, Marshall CB, Witt BL, Birdsong GG, Crothers BA. Arch Pathol Lab Med. 2014 Apr 2.

Genetic variation at 8q24, family history of cancer, and upper gastrointestinal cancers in a Chinese population. Tarleton HP, Chang SC, Park SL, Cai L, Ding B, He N, Hussain SK, Jiang Q, Mu LN, Rao J, Wang H, You NC, Yu SZ, Zhao JK, Zhang ZF. Fam Cancer. 2014 Mar;13(1):45-56. doi: 10.1007/s10689-013-9673-4.

Modulation of BAG-1 expression alters the sensitivity of breast cancer cells to tamoxifen. Liu H, Lu S, Gu L, Gao Y, Wang T, Zhao J, Rao J, Chen J, Hao X, Tang SC. Cell Physiol Biochem. 2014;33(2):365-74. doi: 10.1159/000356676. Epub 2014 Feb 6.

Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies. Lu S, Qin X, Yuan S, Li Y, Wang L, Jin Y, Zeng G, Yen L, Hu J, Dang T, Song S, Hou Q, Rao J. Int J Clin Exp Med. 2014 Mar 15;7(3):597-606. eCollection 2014.

PIAS1 regulates breast tumorigenesis through selective epigenetic gene silencing. Liu B, Tahk S, Yee KM, Yang R, Yang Y, Mackie R, Hsu C, Chernishof V, O'Brien N, Jin Y, Fan G, Lane TF, Rao J, Slamon D, Shuai K. PLoS One. 2014 Feb 24;9(2):e89464. doi: 10.1371/journal.pone.0089464. eCollection 2014.

Quantitative diagnosis of malignant pleural effusions by single-cell mechanophenotyping. Tse HT, Gossett DR, Moon YS, Masaeli M, Sohsman M, Ying Y, Mislick K, Adams RP, Rao J, Di Carlo D. Sci Transl Med. 2013 Nov 20;5(212):212ra163. doi: 10.1126/scitranslmed.3006559.

Colorectal cancer screening with fecal occult blood test: A 22-year cohort study. Jin P, Wu ZT, Li SR, Li SJ, Wang JH, Wang ZH, Lu JG, Cui XJ, Han Y, Rao J, Sheng JQ. Oncol Lett. 2013 Aug;6(2):576-582. Epub 2013 Jun 14.

Effects of Lung Support Formula on respiratory symptoms among older adults: results of a three-month follow-up study in Shanghai, China. Cai Y, Shi R, Song H, Shang M, Shen T, Shariff M, Kami K, Gu P, Nguyen T, Rao J. Nutr J. 2013 May 6;12:57. doi: 10.1186/1475-2891-12-57.

A feasibility study of the intraductal administration of chemotherapy. Love SM, Zhang W, Gordon EJ, Rao J, Yang H, Li J, Zhang B, Wang X, Chen G, Zhang B. Cancer Prev Res (Phila). 2013 Jan;6(1):51-8. doi: 10.1158/1940-6207.CAPR-12-0228. Epub 2012 Nov 20. Erratum in: Cancer Prev Res (Phila). 2013 May;6(5):506.

Microfluidic purification and concentration of malignant pleural effusions for improved molecular and cytomorphological diagnostics. Che J, Mach AJ, Go DE, Talati I, Ying Y, Rao J, Kulkarni RP, Di Carlo D. PLoS One. 2013 Oct 28;8(10):e78194. doi: 10.1371/journal.pone.0078194. eCollection 2013.

Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells. He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J. Exp Mol Med. 2012 Dec 31;44(12):723-32. doi: 10.3858/emm.2012.44.12.079.

Green tea inhibits cycolooxygenase-2 in non-small cell lung cancer cells through the induction of Annexin-1. Lu QY, Jin Y, Mao JT, Zhang ZF, Heber D, Dubinett SM, Rao J. Biochem Biophys Res Commun. 2012 Nov 2;427(4):725-30. doi: 10.1016/j.bbrc.2012.09.125. Epub 2012 Oct 2. View abstract here

Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells. Sharma S, Santiskulvong C, Bentolila LA, Rao J, Dorigo O, Gimzewski JK. Nanomedicine. 2012 Jul;8(5):757-66. doi: 10.1016/j.nano.2011.09.015. Epub 2011 Oct 22. View abstract here

A joint effect of new Western diet and retinoid X receptor a prostate-specific knockout with development of high-grade prostatic intraepithelial neoplasia in mice--a preliminary study. Mao GE, Harris DM, Moro A, Heber D, Roy-Burman P, Zhang ZF, Rao J. Prostate. 2012 Jul 1;72(10):1052-9. doi: 10.1002/pros.22496. Epub 2012 Feb 7. View abstract here

Hydrodynamic stretching of single cells for large population mechanical phenotyping. Gossett DR, Tse HT, Lee SA, Ying Y, Lindgren AG, Yang OO, Rao J, Clark AT, Di Carlo D. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7630-5. doi: 10.1073/pnas.1200107109. Epub 2012 Apr 30. View abstract here

Predictors of resolution of complex atypical hyperplasia or grade 1 endometrial adenocarcinoma in premenopausal women treated with progestin therapy. Penner KR, Dorigo O, Aoyama C, Ostrzega N, Balzer BL, Rao J, Walsh CS, Cass I, Holschneider CH. Gynecol Oncol. 2012 Mar;124(3):542-8. doi: 10.1016/j.ygyno.2011.11.004. Epub 2011 Nov 10. View abstract here

PubMed: JianYu Rao


Rao, Nagesh, PhD, FACMG

Novel three-dimensional in vitro models of ovarian endometriosis. Brueggmann D, Templeman C, Starzinski-Powitz A, Rao NP, Gayther SA, Lawrenson K. J Ovarian Res. 2014 Feb 6;7(1):17. doi: 10.1186/1757-2215-7-17.

One in four individuals of African-American ancestry harbors a 5.5kb deletion at chromosome 11q13.1. Zainabadi K, Jain AV, Donovan FX, Elashoff D, Rao NP, Murty VV, Chandrasekharappa SC, Srivatsan ES. Genomics. 2014 Jan 10. pii: S0888-7543(14)00002-0. doi: 10.1016/j.ygeno.2014.01.001. [Epub ahead of print]

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, Reed R, Nelson SF, Cloughesy TF, James CD, Rao PN, Kornblum HI, Heath JR, Cavenee WK, Furnari FB, Mischel PS. Science. 2014 Jan 3;343(6166):72-6. doi: 10.1126/science.1241328. Epub 2013 Dec 5.

Epstein-Barr virus patterns in US Burkitt lymphoma tumors from the SEER residual tissue repository during 1979-2009. Mbulaiteye SM, Pullarkat ST, Nathwani BN, Weiss LM, Rao N, Emmanuel B, Lynch CF, Hernandez B, Neppalli V, Hawes D, Cockburn MG, Kim A, Williams M, Altekruse S, Bhatia K, Goodman MT, Cozen W. APMIS. 2014 Jan;122(1):5-15. doi: 10.1111/apm.12078. Epub 2013 Apr 23.

A case of pediatric B-Lymphoblastic leukemia presenting with a t(9;12)(p24;q11.2) involving JAK2 and concomitant MLL rearrangement with apparent insertion at 6q27. Tirado CA, Shabsovich D, Denicola M, Rao D, Yang L, Garcia R, Rao N. Biomark Res. 2013 Nov 25;1(1):31. doi: 10.1186/2050-7771-1-31.

The role of miRNA in inflammation and autoimmunity. Singh RP, Massachi I, Manickavel S, Singh S, Rao NP, Hasan S, Mc Curdy DK, Sharma S, Wong D, Hahn BH, Rehimi H. Autoimmun Rev. 2013 Oct;12(12):1160-5. doi: 10.1016/j.autrev.2013.07.003. Epub 2013 Jul 14. View abstract here

Correction: The CD44high Tumorigenic Subsets in Lung Cancer Biospecimens Are Enriched for Low miR-34a Expression. Basak SK, Veena MS, Oh S, Lai C, Vangala S, Elashoff D, Fishbein MC, Sharma S, Rao NP, Rao D, Phan R, Srivatsan ES, Batra RK. PLoS One. 2013 Sep 30;8(9). doi: 10.1371/annotation/9ae8db84-5d44-4a9c-bb80-47c9d68820ea. View abstract here

Heterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma. Chang MY, Rao NP, Burgess BL, Johnson L, McCannel TA. Mol Vis. 2013 Sep 7;19:1892-900. View abstract here

HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Nguyen Kovochich A, Arensman M, Lay AR, Rao NP, Donahue T, Li X, French SW, Dawson DW. Cancer. 2013 Feb 1;119(3):529-39. doi: 10.1002/cncr.27725. Epub 2012 Aug 22. View abstract here

Atypical rearrangement involving 3'[email protected] and a breakpoint at least 400 Kb upstream of an intact MYC in a CLL patient with an apparently balanced t(8;14)(q24.1;q32) and negative MYC expression. Amarillo I, Bui PH, Kantarci S, Rao N, Shackley BS, García R, Tirado CA. Mol Cytogenet. 2013 Feb 1;6(1):5. doi: 10.1186/1755-8166-6-5. View abstract here

Deletions of chromosomes 3p and 14q molecularly subclassify clear cell renal cell carcinoma. Kroeger N, Klatte T, Chamie K, Rao PN, Birkhäuser FD, Sonn GA, Riss J, Kabbinavar FF, Belldegrun AS, Pantuck AJ. Cancer. 2013 Jan 18. doi: 10.1002/cncr.27947. View abstract here

Gain of chromosome 8q is associated with metastases and poor survival of patients with clear cell renal cell carcinoma. Klatte T, Kroeger N, Rampersaud EN, Birkhäuser FD, Logan JE, Sonn G, Riss J, Rao PN, Kabbinavar FF, Belldegrun AS, Pantuck AJ. Cancer. 2012 Dec 1;118(23):5777-82. doi: 10.1002/cncr.27607. Epub 2012 May 17. View abstract here

Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large B-cell lymphoma: a review of the literature. Tirado CA, Chen W, García R, Kohlman KA, Rao N. J Hematol Oncol. 2012 Sep 11;5:54. doi: 10.1186/1756-8722-5-54. Review. View abstract here

"T-cell prolymphocytic leukemia (T-PLL), a heterogeneous disease exemplified by two cases and the important role of cytogenetics: a multidisciplinary approach". Tirado CA, Starshak P, Delgado P, Rao N. Exp Hematol Oncol. 2012 Aug 20;1(1):21. doi: 10.1186/2162-3619-1-21. View abstract here

Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. Exp Hematol. 2012 Jan;40(1):3-13.e3. doi: 10.1016/j.exphem.2011.09.009. Epub 2011 Oct 12. View abstract here

A Comprehensive Update on Molecular and Cytogenetic Abnormalities in T-cell Prolymphocytic Leukemia (T-pll). Delgado P, Starshak P, Rao N, Tirado CA. J Assoc Genet Technol. 2012;38(4):193-8. View abstract here

PubMed: Nagesh Rao


Reed, Elaine, PhD


Antibody-mediated graft injury: complement-dependent and complement-independent mechanisms. Valenzuela NM, McNamara JT, Reed EF. Curr Opin Organ Transplant. 2014 Feb;19(1):33-40. doi: 10.1097/MOT.0000000000000040. Review.

Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Tait BD, Süsal C, Gebel HM, Nickerson PW, Zachary AA, Claas FH, Reed EF, Bray RA, Campbell P, Chapman JR, Coates PT, Colvin RB, Cozzi E, Doxiadis II, Fuggle SV, Gill J, Glotz D, Lachmann N, Mohanakumar T, Suciu-Foca N, Sumitran-Holgersson S, Tanabe K, Taylor CJ, Tyan DB, Webster A, Zeevi A, Opelz G. Transplantation. 2013 Jan 15;95(1):19-47. doi: 10.1097/TP.0b013e31827a19cc

Antibodies in transplantation: the effects of HLA and non-HLA antibody binding and mechanisms of injury. Valenzuela NM, Reed EF. Methods Mol Biol. 2013;1034:41-70. doi: 10.1007/978-1-62703-493-7_2.

Comprehensive Assessment and Standardization of Solid Phase Multiplex-Bead Arrays for the Detection of Antibodies to HLA-Drilling Down on Key Sources of Variation. Reed EF, Rao P, Zhang Z, Gebel H, Bray RA, Guleria I, Lunz J, Mohanakumar T, Nickerson P, Tambur AR, Zeevi A, Heeger PS, Gjertson D. Am J Transplant. 2013 Sep 18. doi: 10.1111/ajt.12462. View abstract here

The multidimensional perspective of cardiac allograft rejection. Deng M, Cadeiras M, Reed EF. Curr Opin Organ Transplant. 2013 Aug 29. View abstract here

HLA Class I Antibodies Trigger Increased Adherence of Monocytes to Endothelial Cells by Eliciting an Increase in Endothelial P-Selectin and, Depending on Subclass, by Engaging FcγRs. Valenzuela NM, Mulder A, Reed EF. J Immunol. 2013 Jun 15;190(12):6635-50. doi: 10.4049/jimmunol.1201434. Epub 2013 May 20. View abstract here

Kidney paired donation in the presence of donor-specific antibodies. Blumberg JM, Gritsch HA, Reed EF, Cecka JM, Lipshutz GS, Danovitch GM, McGuire S, Gjertson DW, Veale JL. Kidney Int. 2013 May 29. doi: 10.1038/ki.2013.206. View abstract here

Pathologic findings in lung allografts with anti-HLA antibodies. Denicola MM, Weigt SS, Belperio JA, Reed EF, Ross DJ, Wallace WD. J Heart Lung Transplant. 2013 Mar;32(3):326-32. doi: 10.1016/j.healun.2012.11.018. Epub 2013 Jan 10. View abstract here

Mechanisms of action and effects of antibodies on the cells of the allograft. Reed EF. Hum Immunol. 2012 Dec;73(12):1211-2. doi: 10.1016/j.humimm.2012.09.011. Epub 2012 Oct 3. No abstract available. View abstract here

HLA class I: an unexpected role in integrin ß4 signaling in endothelial cells. Zhang X, Reed EF. Hum Immunol. 2012 Dec;73(12):1239-44. doi: 10.1016/j.humimm.2012.06.013. Epub 2012 Jul 10. View abstract here

HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells. Ziegler ME, Jin YP, Young SH, Rozengurt E, Reed EF. Am J Physiol Cell Physiol. 2012 Oct 15;303(8):C872-82. doi: 10.1152/ajpcell.00199.2012. Epub 2012 Aug 22. View abstract here

Serum creatinine detection by a conducting-polymer-based electrochemical sensor to identify allograft dysfunction. Wei F, Cheng S, Korin Y, Reed EF, Gjertson D, Ho CM, Gritsch HA, Veale J. Anal Chem. 2012 Sep 18;84(18):7933-7. doi: 10.1021/ac3016888. Epub 2012 Aug 24. View abstract here

Usefulness of immune monitoring in lung transplantation using adenosine triphosphate production in activated lymphocytes. Shino MY, Weigt SS, Saggar R, Elashoff D, Derhovanessian A, Gregson AL, Saggar R, Reed EF, Kubak BM, Lynch JP 3rd, Belperio JA, Ardehali A, Ross DJ. J Heart Lung Transplant. 2012 Sep;31(9):996-1002. doi: 10.1016/j.healun.2012.05.012. View abstract here

HLA class I antibody-mediated endothelial and smooth muscle cell activation. Zhang X, Valenzuela NM, Reed EF. Curr Opin Organ Transplant. 2012 Aug;17(4):446-51. doi: 10.1097/MOT.0b013e328355f1c2. View abstract here

Characterization of the endothelial cell cytoskeleton following HLA class I ligation. Ziegler ME, Souda P, Jin YP, Whitelegge JP, Reed EF.PLoS One. 2012;7(1):e29472. doi: 10.1371/journal.pone.0029472. Epub 2012 Jan 11. View abstract here

PubMed: Elaine Reed


Rozengurt, Nora

Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium. Rey O, Chang W, Bikle D, Rozengurt N, Young SH, Rozengurt E. J Biol Chem. 2012 Jan 6;287(2):1158-67. doi: 10.1074/jbc.M111.274589. Epub 2011. View abstract here

Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. Exp Hematol. 2012 Jan;40(1):3-13.e3. doi: 10.1016/j.exphem.2011.09.009. Epub 2011 Oct 12. View abstract here

Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells. Young SH, Rozengurt N, Sinnett-Smith J, Rozengurt E. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G356-66. doi: 10.1152/ajpgi.00025.2012. Epub 2012 May 17. View abstract here

Gene therapy/bone marrow transplantation in ADA-deficient mice: roles of enzyme-replacement therapy and cytoreduction. Carbonaro DA, Jin X, Wang X, Yu XJ, Rozengurt N, Kaufman ML, Wang X, Gjertson D, Zhou Y, Blackburn MR, Kohn DB. Blood. 2012 Nov 1;120(18):3677-87. doi: 10.1182/blood-2012-02-408591. Epub 2012 Jul 25. View abstract here

Long-term survival of the juvenile lethal arginase-deficient mouse with AAV gene therapy. Lee EK, Hu C, Bhargava R, Rozengurt N, Stout D, Grody WW, Cederbaum SD, Lipshutz GS. Mol Ther. 2012 Oct;20(10):1844-51. doi: 10.1038/mt.2012.129. Epub 2012 Jul 3. View abstract here

AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse. Lee EK, Hu C, Bhargava R, Ponnusamy R, Park H, Novicoff S, Rozengurt N, Marescau B, De Deyn P, Stout D, Schlichting L, Grody WW, Cederbaum SD, Lipshutz GS. Gene Ther. 2013 Feb 7. View abstract here

Correction: Interruption of CXCL13-CXCR5 Axis Increases Upper Genital Tract Pathology and Activation of NKT Cells following Chlamydial Genital Infection. Jiang J, Karimi O, Ouburg S, Champion CI, Khurana A, Liu G, Freed A, Pleijster J, Rozengurt N, Land JA, Surcel HM, Tiitinen A, Paavonen J, Kronenberg M, Morré SA, Kelly KA. PLoS One. 2013 May 24;8(5). doi: 10.1371/annotation/2b6aab70-3c92-490e-86f0-ae15787dfa6e. View abstract here

PubMed: Nora Rozengurt


Said, Jonathan, MD


Burkitt Lymphoma and MYC: What Else Is New? Said J, Lones M, Yea S. Adv Anat Pathol. 2014 May;21(3):160-5. doi: 10.1097/PAP.0b013e3182a92cde. View abstract here

LNK (SH2B3): paradoxical effects in ovarian cancer. Ding LW, Sun QY, Lin DC, Chien W, Hattori N, Dong XM, Gery S, Garg M, Doan NB, Said JW, Xiao JF, Yang H, Liu LZ, Meng X, Huang RY, Tang K, Koeffler HP. Oncogene. 2014 Apr 7. doi: 10.1038/onc.2014.34. [Epub ahead of print] View abstract here

Diagnostic Accuracy of a Defined Immunophenotypic and Molecular Genetic Approach for Peripheral T/NK-cell Lymphomas: A North American PTCL Study Group Project. Hsi ED, Said J, Macon WR, Rodig SJ, Ondrejka SL, Gascoyne RD, Morgan EA, Dorfman DM, Maurer MJ, Dogan A. Am J Surg Pathol. 2014 Mar 10. [Epub ahead of print] View abstract here

Malignant Melanoma With Neural Differentiation: An Exceptional Case Report and Brief Review of the Pertinent Literature. Su A, Dry SM, Binder SW, Said J, Shintaku P, Sarantopoulos GP. Am J Dermatopathol. 2013 Jun 18. View abstract here

Effect of a low-fat fish oil diet on proinflammatory eicosanoids and cell-cycle progression score in men undergoing radical prostatectomy. Galet C, Gollapudi K, Stepanian S, Byrd JB, Henning SM, Grogan T, Elashoff D, Heber D, Said J, Cohen P, Aronson WJ. Cancer Prev Res (Phila). 2014 Jan;7(1):97-104. doi: 10.1158/1940-6207.CAPR-13-0261. Epub 2013 Oct 29. View abstract here

Peripheral T-cell and NK-cell lymphomas and their mimics; taking a step forward - report on the lymphoma workshop of the XVIth meeting of the European Association for Haematopathology and the Society for Hematopathology. Attygalle AD, Cabeçadas J, Gaulard P, Jaffe ES, de Jong D, Ko YH, Said J, Klapper W. Histopathology. 2014 Jan;64(2):171-99. doi: 10.1111/his.12251. Epub 2013 Oct 16. View abstract here

Laminin-5γ-2 (LAMC2) is highly expressed in anaplastic thyroid carcinoma and is associated with tumor progression, migration, and invasion by modulating signaling of EGFR. Garg M, Kanojia D, Okamoto R, Jain S, Madan V, Chien W, Sampath A, Ding LW, Xuan M, Said JW, Doan NB, Liu LZ, Yang H, Gery S, Braunstein GD, Koeffler HP. J Clin Endocrinol Metab. 2014 Jan;99(1):E62-72. doi: 10.1210/jc.2013-2994. Epub 2013 Dec 20. View abstract here

Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea. Wang P, Vadgama JV, Said JW, Magyar CE, Doan N, Heber D, Henning SM. J Nutr Biochem. 2014 Jan;25(1):73-80. doi: 10.1016/j.jnutbio.2013.09.005. Epub 2013 Oct 10. View abstract here

Off-target effects of c-MET inhibitors on thyroid cancer cells. Zhou Y, Zhao C, Gery S, Braunstein GD, Okamoto R, Alvarez R, Miles SA, Doan NB, Said JW, Gu J, Phillip Koeffler H. Mol Cancer Ther. 2014 Jan;13(1):134-43. doi: 10.1158/1535-7163.MCT-13-0187. Epub 2013 Oct 29. View abstract here

Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications. Wang S, Tzankov A, Xu-Monette ZY, Hoeller S, Wang SA, Richards KL, Zhang S, Said JW, Medeiros LJ, Young KH.Hum Pathol. 2013 Dec;44(12):2658-67. doi: 10.1016/j.humpath.2013.07.007. Epub 2013 Sep 24. View abstract here

T-cell LPD of the GIT: first do no harm. Said J. Blood. 2013 Nov 21;122(22):3548-50. doi: 10.1182/blood-2013-09-526368. View abstract here

Plasmacytoma-like post-transplant lymphoproliferative disorder seen in pediatric combined liver and intestinal transplant recipients. Plant AS, Venick RS, Farmer DG, Upadhyay S, Said J, Kempert P. Pediatr Blood Cancer. 2013 Nov;60(11):E137-9. doi: 10.1002/pbc.24632. Epub 2013 Jun 27. View abstract here

PIAS4 is an activator of hypoxia signaling via VHL suppression during growth of pancreatic cancer cells. Chien W, Lee KL, Ding LW, Wuensche P, Kato H, Doan NB, Poellinger L, Said JW, Koeffler HP. Br J Cancer. 2013 Oct 1;109(7):1795-804. doi: 10.1038/bjc.2013.531. Epub 2013 Sep 3. View abstract here

Levels of murine, but not human, CXCL13 are greatly elevated in NOD-SCID mice bearing the AIDS-associated Burkitt lymphoma cell line, 2F7. Widney DP, Olafsen T, Wu AM, Kitchen CM, Said JW, Smith JB, Peña G, Magpantay LI, Penichet ML, Martinez-Maza O. PLoS One. 2013 Aug 2;8(8):e72414. doi: 10.1371/journal.pone.0072414. Print 2013. View abstract here

Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts. Galet C, Gray A, Said JW, Castor B, Wan J, Beltran PJ, Calzone FJ, Elashoff D, Cohen P, Aronson WJ. Int J Mol Sci. 2013 Jul 3;14(7):13782-95. doi: 10.3390/ijms140713782. View abstract here

The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer. Aribi A, Gery S, Lee DH, Thoennissen NH, Thoennissen GB, Alvarez R, Ho Q, Lee K, Doan NB, Chan KT, Toh M, Said JW, Koeffler HP. Int J Cancer. 2012 Nov 20. doi: 10.1002/ijc.27950. View abstract here

Pimary central nervous system histiocytic sarcoma presenting as a postradiation sarcoma: case report and literature review. Wu W, Tanrivermis Sayit A, Vinters HV, Pope W, Mirsadraei L, Said J. Hum Pathol. 2013 Jun;44(6):1177-83. doi: 10.1016/j.humpath.2012.11.002. Epub 2013 Jan 26. View abstract here

Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival. Lee DH, Amanat S, Goff C, Weiss LM, Said JW, Doan NB, Sato-Otsubo A, Ogawa S, Forscher C, Koeffler HP. Oncogenesis. 2013 May 20;2:e47. doi: 10.1038/oncsis.2013.10. View abstract here

Inhibiting proliferation of gefitinib-resistant, non-small cell lung cancer. Sudo M, Chin TM, Mori S, Doan NB, Said JW, Akashi M, Koeffler HP. Cancer Chemother Pharmacol. 2013 May;71(5):1325-34. doi: 10.1007/s00280-013-2132-y. Epub 2013 Mar 21. View abstract here

Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers. Lin DC, Xu L, Ding LW, Sharma A, Liu LZ, Yang H, Tan P, Vadgama J, Karlan BY, Lester J, Urban N, Schummer M, Doan N, Said JW, Sun H, Walsh M, Thomas CJ, Patel P, Yin D, Chan D, Koeffler HP. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6109-14. doi: 10.1073/pnas.1218206110. Epub 2013 Mar 27. View abstract here

Mimics of cutaneous lymphoma: report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop. Sarantopoulos GP, Palla B, Said J, Kinney MC, Swerdlow SM, Willemze R, Binder SW. Am J Clin Pathol. 2013 Apr;139(4):536-51. doi: 10.1309/AJCPX4BXTP2QBRKO. View abstract here

Mycosis fungoides: report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop. Song SX, Willemze R, Swerdlow SH, Kinney MC, Said JW. Am J Clin Pathol. 2013 Apr;139(4):466-90. doi: 10.1309/AJCPOBDP2OQAJ5BR. View abstract here

Growth inhibition of pancreatic cancer cells by Histone Deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo. Chien W, Lee DH, Zheng Y, Wuensche P, Alvarez R, Wen DL, Aribi AM, Thean SM, Doan NB, Said JW, Koeffler HP. Mol Carcinog. 2013 Mar 8. doi: 10.1002/mc.22024. [Epub ahead of print]

miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme. Yin D, Ogawa S, Kawamata N, Leiter A, Ham M, Li D, Doan NB, Said JW, Black KL, Phillip Koeffler H. Oncogene. 2013 Feb 28;32(9):1155-63. doi: 10.1038/onc.2012.132. Epub 2012 May 14. View abstract here

High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Myklebust JH, Irish JM, Brody J, Czerwinski DK, Houot R, Kohrt HE, Timmerman J, Said J, Green MR, Delabie J, Kolstad A, Alizadeh AA, Levy R. Blood. 2013 Feb 21;121(8):1367-76. doi: 10.1182/blood-2012-04-421826. Epub 2013 Jan 7. View abstract here

Acral lymphomatoid papulosis associated with poikilodermatous mycosis fungoides. Magorien J, Hillman JD, Pinter-Brown LC, Said J, Chiu MW. Dermatol Online J. 2013 Feb 15;19(2):1. View abstract here

KSHV/HHV8-negative effusion-based lymphoma, a distinct entity associated with fluid overload states. Alexanian S, Said J, Lones M, Pullarkat ST. Am J Surg Pathol. 2013 Feb;37(2):241-9. doi: 10.1097/PAS.0b013e318267fabc. View abstract here

IGFBP-3 nuclear localization predicts human prostate cancer recurrence. Seligson DB, Yu H, Tze S, Said J, Pantuck AJ, Cohen P, Lee KW. Horm Cancer. 2013 Feb;4(1):12-23. doi: 10.1007/s12672-012-0124-8. Epub 2012 Sep 26. View abstract here

Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models. Birkhäuser FD, Koya RC, Neufeld C, Rampersaud EN, Lu X, Micewicz ED, Chodon T, Atefi M, Kroeger N, Chandramouli GV, Li G, Said JW, McBride WH, Kabbinavar FF, Ribas A, Pantuck AJ, Belldegrun AS, Riss J. J Immunother. 2013 Feb;36(2):102-11. doi: 10.1097/CJI.0b013e31827bec97. View abstract here

Pathology quiz case 1. IgG4-related sialadenitis as a presenting symptom of IgG4-related disease. Yuan JT, Said J, Blackwell KE. JAMA Otolaryngol Head Neck Surg. 2013 Feb;139(2):193-5. doi: 10.1001/jamaoto.2013.1268a. View abstract here

Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments. Fu M, Brewer S, Olafsen T, Wu AM, Gordon LK, Said J, Braun J, Wadehra M. Mol Imaging Biol. 2013 Feb;15(1):68-78. doi: 10.1007/s11307-012-0558-y. View abstract here

Antitumor activity of a pyrrole-imidazole polyamide. Yang F, Nickols NG, Li BC, Marinov GK, Said JW, Dervan PB. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1863-8. doi: 10.1073/pnas.1222035110. Epub 2013 Jan 14. View abstract here

Association between tumor-associated macrophage infiltration, high grade prostate cancer, and biochemical recurrence after radical prostatectomy. Gollapudi K, Galet C, Grogan T, Zhang H, Said JW, Huang J, Elashoff D, Freedland SJ, Rettig M, Aronson WJ. Am J Cancer Res. 2013 Nov 1;3(5):523-9. eCollection 2013. View abstract here

Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study. Hoeller S, Zhou Y, Kanagal-Shamanna R, Xu-Monette ZY, Hoehn D, Bihl M, Swerdlow SH, Rosenwald A, Ott G, Said J, Dunphy CH, Bueso-Ramos CE, Lin P, Wang M, Miranda RN, Tzankov A, Medeiros LJ, Young KH. Hum Pathol. 2013 Jan;44(1):110-21. doi: 10.1016/j.humpath.2012.04.022. Epub 2012 Aug 31. Review. View abstract here

Aggressive B-cell lymphomas: how many categories do we need? Said JW. Mod Pathol. 2013 Jan;26 Suppl 1:S42-56. doi: 10.1038/modpathol.2012.178. Epub 2012 Nov 16. View abstract here

Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death. Clark MC, Pang M, Hsu DK, Liu FT, de Vos S, Gascoyne RD, Said J, Baum LG. Blood. 2012 Nov 29;120(23):4635-44. doi: 10.1182/blood-2012-06-438234. Epub 2012 Oct 12. View abstract here

Polyphenols in brewed green tea inhibit prostate tumor xenograft growth by localizing to the tumor and decreasing oxidative stress and angiogenesis. Henning SM, Wang P, Said J, Magyar C, Castor B, Doan N, Tosity C, Moro A, Gao K, Li L, Heber D. J Nutr Biochem. 2012 Nov;23(11):1537-42. doi: 10.1016/j.jnutbio.2011.10.007. Epub 2012 Mar 8. View abstract here

Primary carcinoid tumor of urinary bladder discovered on pelvic magnetic resonance imaging. Kaplan AL, Margolis DJ, Said J, Chin AI. Urology. 2012 Nov;80(5):e55-7. doi: 10.1016/j.urology.2012.08.009. View abstract here

Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma. Chao C, Silverberg MJ, Martínez-Maza O, Chi M, Abrams DI, Haque R, Zha HD, McGuire M, Xu L, Said J. Clin Cancer Res. 2012 Sep 1;18(17):4702-12. Epub 2012 Jun 18. View abstract here

Transcription factor CCAAT/enhancer-binding protein alpha and critical circadian clock downstream target gene PER2 are highly deregulated in diffuse large B-cell lymphoma. Thoennissen NH, Thoennissen GB, Abbassi S, Nabavi-Nouis S, Sauer T, Doan NB, Gery S, Müller-Tidow C, Said JW, Koeffler HP. Leuk Lymphoma. 2012 Aug;53(8):1577-85. doi: 10.3109/10428194.2012.658792. Epub 2012 Feb 21. View abstract here

Primary effusion lymphoma involving the cerebrospinal fluid. Moatamed NA, Song SX, Apple SK, Said JW. Diagn Cytopathol. 2012 Jul;40(7):635-8. doi: 10.1002/dc.21653. Epub 2011 Mar 4. View abstract here

Effect of a low-fat diet combined with IGF-1 receptor blockade on 22Rv1 prostate cancer xenografts. Konijeti R, Koyama S, Gray A, Barnard RJ, Said JW, Castor B, Elashoff D, Wan J, Beltran PJ, Calzone FJ, Cohen P, Galet C, Aronson WJ. Mol Cancer Ther. 2012 Jul;11(7):1539-46. doi: 10.1158/1535-7163.MCT-11-1003. Epub 2012 May 4. View abstract here

Impact of pathological tumour characteristics in patients with sarcomatoid renal cell carcinoma. Shuch B, Bratslavsky G, Shih J, Vourganti S, Finley D, Castor B, Treat E, Linehan WM, Pantuck AJ, Said JW, Belldegrun AS. BJU Int. 2012 Jun;109(11):1600-6. doi: 10.1111/j.1464-410X.2011.10785.x. Epub 2012 Jan 5. View abstract here

Inecalcitol, an analog of 1a,25(OH)(2) D(3) , induces growth arrest of androgen-dependent prostate cancer cells. Okamoto R, Delansorne R, Wakimoto N, Doan NB, Akagi T, Shen M, Ho QH, Said JW, Koeffler HP. Int J Cancer. 2012 May 15;130(10):2464-73. doi: 10.1002/ijc.26279. Epub 2011 Aug 27. View abstract here

A Cancer and Leukemia Group B multi-center study of DA-EPOCH-rituximab in untreated diffuse large B-cell lymphoma with analysis of outcome by molecular subtype. Wilson WH, Jung SH, Porcu P, Hurd D, Johnson J, Martin SE, Czuczman M, Lai R, Said J, Chadburn A, Jones D, Dunleavy K, Canellos G, Zelenetz AD, Cheson BD, Hsi ED; Cancer Leukemia Group B. Haematologica. 2012 May;97(5):758-65. doi: 10.3324/haematol.2011.056531. Epub 2011 Dec 1. View abstract here

Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Los Angeles County. Kelesidis T, Humphries R, Terashita D, Eshaghian S, Territo MC, Said J, Lewinski M, Currier JS, Pegues D. J Med Virol. 2012 May;84(5):777-85. doi: 10.1002/jmv.23267. View abstract here

Risk of lymphoma in patients receiving antitumor necrosis factor therapy: a meta-analysis of published randomized controlled studies. Wong AK, Kerkoutian S, Said J, Rashidi H, Pullarkat ST. Clin Rheumatol. 2012 Apr;31(4):631-6. doi: 10.1007/s10067-011-1895-y. Epub 2011 Nov 18. View abstract here

Mantle cell lymphoma as a component of composite lymphoma: clinicopathologic parameters and biologic implications. Papathomas TG, Venizelos I, Dunphy CH, Said JW, Wang ML, Campo E, Swerdlow SH, Chan JC, Bueso-Ramos CE, Weisenburger DD, Medeiros LJ, Young KH. Hum Pathol. 2012 Apr;43(4):467-80. doi: 10.1016/j.humpath.2011.08.024. Epub 2012 Jan 4. Review. View abstract here

Effect of dasatinib against thyroid cancer cell lines in vitro and a xenograft model in vivo. Chan D, Tyner JW, Chng WJ, Bi C, Okamoto R, Said J, Ngan BD, Braunstein GD, Koeffler HP. Oncol Lett. 2012 Apr 1;3(4):807-815. Epub 2012 Jan 20. View abstract here

Histopathology of brow fat in thyroid-associated orbitopathy. Hwang CJ, Khadavi NM, Papageorgiou K, Said J, Chong K, Lee D, Smith TJ, Goldberg RA, Douglas RS. Ophthal Plast Reconstr Surg. 2012 Jan;28(1):27-9. doi: 10.1097/IOP.0b013e31822e9560. View abstract here

Cutaneous papilloma and squamous cell carcinoma therapy utilizing nanosecond pulsed electric fields (nsPEF). Yin D, Yang WG, Weissberg J, Goff CB, Chen W, Kuwayama Y, Leiter A, Xing H, Meixel A, Gaut D, Kirkbir F, Sawcer D, Vernier PT, Said JW, Gundersen MA, Koeffler HP. PLoS One. 2012;7(8):e43891. doi: 10.1371/journal.pone.0043891. Epub 2012 Aug 28. View abstract here

Phase II prospective randomized trial of a low-fat diet with fish oil supplementation in men undergoing radical prostatectomy. Aronson WJ, Kobayashi N, Barnard RJ, Henning S, Huang M, Jardack PM, Liu B, Gray A, Wan J, Konijeti R, Freedland SJ, Castor B, Heber D, Elashoff D, Said J, Cohen P, Galet C. Cancer Prev Res (Phila). 2011 Dec;4(12):2062-71. doi: 10.1158/1940-6207.CAPR-11-0298. Epub 2011 Oct 25. View abstract here

Global Igfbp1 deletion does not affect prostate cancer development in a c-Myc transgenic mouse model. Gray A, Aronson WJ, Barnard RJ, Mehta H, Wan J, Said J, Cohen P, Galet C. J Endocrinol. 2011 Dec;211(3):297-304. doi: 10.1530/JOE-11-0240. Epub 2011 Sep 8. View abstract here

The chromophobe tumor grading system is the preferred grading scheme for chromophobe renal cell carcinoma. Finley DS, Shuch B, Said JW, Galliano G, Jeffries RA, Afifi AA, Castor B, Magyar C, Sadaat A, Kabbinavar FF, Belldegrun AS, Pantuck AJ. J Urol. 2011 Dec;186(6):2168-74. doi: 10.1016/j.juro.2011.07.068. Epub 2011 Oct 19. View abstract here

Quality of pathological reporting for renal cell cancer: implications for systemic therapy, prognostication and surveillance. Shuch B, Pantuck AJ, Pouliot F, Finley DS, Said JW, Belldegrun AS, Saigal C. BJU Int. 2011 Aug;108(3):343-8. doi: 10.1111/j.1464-410X.2010.09871.x. Epub 2010 Nov 19. View abstract here

IGFBP-3 is a metastasis suppression gene in prostate cancer. Mehta HH, Gao Q, Galet C, Paharkova V, Wan J, Said J, Sohn JJ, Lawson G, Cohen P, Cobb LJ, Lee KW. Cancer Res. 2011 Aug 1;71(15):5154-63. doi: 10.1158/0008-5472.CAN-10-4513. Epub 2011 Jun 22. View abstract here

Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma. Lee DH, Thoennissen NH, Goff C, Iwanski GB, Forscher C, Doan NB, Said JW, Koeffler HP. Cancer Lett. 2011 Jul 28;306(2):161-70. doi: 10.1016/j.canlet.2011.03.001. Epub 2011 Mar 26. View abstract here

Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells. Andorsky DJ, Yamada RE, Said J, Pinkus GS, Betting DJ, Timmerman JM. Clin Cancer Res. 2011 Jul 1;17(13):4232-44. doi: 10.1158/1078-0432.CCR-10-2660. Epub 2011 May 3. View abstract here

Pathological, immunohistochemical and cytogenetic features of papillary renal cell carcinoma with clear cell features. Klatte T, Said JW, Seligson DB, Rao PN, de Martino M, Shuch B, Zomorodian N, Kabbinavar FF, Belldegrun AS, Pantuck AJ. J Urol. 2011 Jan;185(1):30-5. doi: 10.1016/j.juro.2010.09.013. Epub 2010 Nov 12. View abstract here


PubMed: Jonathan Said


Sarantopoulos, G. Peter, MD
 

Malignant melanoma with neural differentiation: an exceptional case report and brief review of the pertinent literature. Su A, Dry SM, Binder SW, Said J, Shintaku P, Sarantopoulos GP. Am J Dermatopathol. 2014 Jan;36(1):e5-9. doi: 10.1097/DAD.0b013e31828cf90a.

Mimics of cutaneous lymphoma: report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop. Sarantopoulos GP, Palla B, Said J, Kinney MC, Swerdlow SM, Willemze R, Binder SW. Am J Clin Pathol. 2013 Apr;139(4):536-51. doi: 10.1309/AJCPX4BXTP2QBRKO.

PubMed: G. Peter Sarantopoulos


Schiestl, Robert, PhD

Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons. Maier I, Berry DM, Schiestl RH. Radiat Res. 2014 Jan;181(1):45-53. doi: 10.1667/RR13352.1. Epub 2014 Jan 7.

Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity. Yamamoto ML, Maier I, Dang AT, Berry D, Liu J, Ruegger PM, Yang JI, Soto PA, Presley LL, Reliene R, Westbrook AM, Wei B, Loy A, Chang C, Braun J, Borneman J, Schiestl RH. Cancer Res. 2013 Jul 15;73(14):4222-32. doi: 10.1158/0008-5472.CAN-13-0022.

Mouse models of radiation-induced cancers. Rivina L, Schiestl R. Adv Genet. 2013;84:83-122. doi: 10.1016/B978-0-12-407703-4.00003-7.

Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells. Yamamoto ML, Chapman AM, Schiestl RH. Mutat Res. 2013 Jun 5. doi:pii: S0027-5107(13)00096-1. 10.1016/j.mrfmmm.2013.05.003. View abstract here

Mouse models for efficacy testing of agents against radiation carcinogenesis-a literature review. Rivina L, Schiestl R. Int J Environ Res Public Health. 2012 Dec 27;10(1):107-43. doi: 10.3390/ijerph10010107. View abstract here

Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Sobol Z, Schiestl RH. Environ Mol Mutagen. 2012 Mar;53(2):94-100. doi: 10.1002/em.20679. Epub 2011 Oct 21. View abstract here

Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. Exp Hematol. 2012 Jan;40(1):3-13.e3. doi: 10.1016/j.exphem.2011.09.009. Epub 2011 Oct 12. View abstract here

The role of tumour necrosis factor-a and tumour necrosis factor receptor signaling in inflammation-associated systemic genotoxicity. Westbrook AM, Wei B, Hacke K, Xia M, Braun J, Schiestl RH. Mutagenesis. 2012 Jan;27(1):77-86. doi: 10.1093/mutage/ger063. Epub 2011 Oct 6. View abstract here

Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases. Cabeza-Arvelaiz Y, Schiestl RH. PLoS One. 2012;7(9):e44700. doi: 10.1371/journal.pone.0044700. Epub 2012 Sep 7. View abstract here

PubMed: Robert Schiestl


Schiller, Gary, MD

Allogeneic transplantation as therapy for acute myelogenous leukemia in the elderly. Schiller GJ. Biol Blood Marrow Transplant. 2014 Apr;20(4):437-8. doi: 10.1016/j.bbmt.2014.01.024. Epub 2014 Jan 29. No abstract available.

Evolving treatment strategies in patients with high-risk acute myeloid leukemia. Schiller GJ. Leuk Lymphoma. 2014 Mar 7.

High-risk acute myelogenous leukemia: treatment today ... and tomorrow. Schiller GJ. Hematology Am Soc Hematol Educ Program. 2013;2013:201-8. doi: 10.1182/asheducation-2013.1.201.

Myelodysplasia. Schiller GJ, Reese N. Hematology. 2013 Sep;18(5):307-8. doi: 10.1179/1024533213Z.000000000221. View abstract here

High-Dose Cytarabine (HD araC) in the Treatment of Leukemias: a Review. Reese ND, Schiller GJ. Curr Hematol Malig Rep. 2013 Jun;8(2):141-8. doi: 10.1007/s11899-013-0156-3. View abstract here

Secondary hemophagocytic lymphohistiocytosis in adults: an update on diagnosis and therapy. Kleynberg RL, Schiller GJ. Clin Adv Hematol Oncol. 2012 Nov;10(11):726-32. View abstract here

Blastic plasmacytoid dendritic cell neoplasm. Lee JK, Schiller G. Clin Adv Hematol Oncol. 2012 Jan;10(1):60-2. Review. No abstract available. View abstract here

PubMed: Gary Schiller

 


Singh, Ram, MD

Intrinsic hyporesponsiveness of invariant natural killer T cells precedes the onset of lupus. Yang JQ, Kim PJ, Halder RC, Singh RR. Clin Exp Immunol. 2013 Jul;173(1):18-27. doi: 10.1111/cei.12079.

Germline deletion of β2 microglobulin or CD1d reduces anti-phospholipid antibody, but increases autoantibodies against non-phospholipid antigens in the NZB/W F1 model of lupus. Singh RR, Yang JQ, Kim PJ, Halder RC. Arthritis Res Ther. 2013 Mar 27;15(2):R47. View abstract here

Brief treatment with iNKT cell ligand a-galactosylceramide confers a long-term protection against lupus. Yang JQ, Kim PJ, Singh RR. J Clin Immunol. 2012 Feb;32(1):106-13. doi: 10.1007/s10875-011-9590-y. Epub 2011 Oct 15. View abstract here

PubMed: Ram Singh


Smart, Chandra, MD

Cutaneous granulomas and epidermodysplasia verruciformis in early onset combined immunodeficiency syndrome. Wang YT, Geng B, Yoo KY, Stiehm ER, Garcia-Lloret M, Wong D, Smart C, Worswick S, Barnhill RL. Am J Dermatopathol. 2014 Feb;36(2):179-83. doi: 10.1097/DAD.0b013e3182a67f9b.

Atypical fibrous histiocytoma arising in the perianal area: a case report and review of the literature. Wang YT, Smart CN. Am J Dermatopathol. 2014 Feb;36(2):171-3. doi: 10.1097/DAD.0b013e31829bd682.

Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions. Haas M, Sis B, Racusen LC, Solez K, Glotz D, Colvin RB, Castro MC, David DS, David-Neto E, Bagnasco SM, Cendales LC, Cornell LD, Demetris AJ, Drachenberg CB, Farver CF, Farris AB 3rd, Gibson IW, Kraus E, Liapis H, Loupy A, Nickeleit V, Randhawa P, Rodriguez ER, Rush D, Smith RN, Tan CD, Wallace WD, Mengel M; Banff meeting report writing committee. Am J Transplant. 2014 Feb;14(2):272-83. doi: 10.1111/ajt.12590.

An unusual presentation and distribution of generalized eruptive syringomas. Chow C, Gharavi NM, Smart CN, Yashar S, Young LC. Skinmed. 2013 Sep-Oct;11(5):311-2.

Reticulin and NM23 staining in the interpretation of lymph nodal nevus rests. Kanner WA, Barry CI, Smart CN, Frishberg DP, Binder SW, Wick MR. Am J Dermatopathol. 2013 Jun;35(4):452-7. doi: 10.1097/DAD.0b013e318272c104.

PubMed: Chandra Smart


Song, Sophie, MD, PhD

Mycosis fungoides: report of the 2011 society for hematopathology/european association for haematopathology workshop. Song SX, Willemze R, Swerdlow SH, Kinney MC, Said JW. Am J Clin Pathol. 2013 Apr;139(4):466-90. doi: 10.1309/AJCPOBDP2OQAJ5BR. View abstract here

Primary effusion lymphoma involving the cerebrospinal fluid. Moatamed NA, Song SX, Apple SK, Said JW. Diagn Cytopathol. 2012 Jul;40(7):635-8. doi: 10.1002/dc.21653. Epub 2011 Mar 4. View abstract here

PubMed: Sophie Song


Stark, Elena, MD, PhD


Probabilistic mapping of the cervical sympathetic trunk ganglia. Stark ME, Safir I, Wisco JJ. Auton Neurosci. 2014 Apr;181:79-84. doi: 10.1016/j.autneu.2014.01.007. Epub 2014 Jan 24.

Applying the cognitive theory of multimedia learning: an analysis of medical animations. Yue C, Kim J, Ogawa R, Stark E, Kim S. Med Educ. 2013 Apr;47(4):375-87. doi: 10.1111/medu.12090. View abstract here

Extracardiac neural remodeling in humans with cardiomyopathy. Ajijola OA, Wisco JJ, Lambert HW, Mahajan A, Stark E, Fishbein MC, Shivkumar K. Circ Arrhythm Electrophysiol. 2012 Oct;5(5):1010-116. doi: 10.1161/CIRCEP.112.972836. Epub 2012 Aug 23. View abstract here

A heat map of superior cervical ganglion location relative to the common carotid artery bifurcation. Wisco JJ, Stark ME, Safir I, Rahman S. Anesth Analg. 2012 Feb;114(2):462-5. doi: 10.1213/ANE.0b013e31823b676d. Epub 2011 Nov 21. View abstract here

PubMed: Elena Stark


Sullivan, Peggy, MD

A 92-gene cancer classifier predicts the site of origin for neuroendocrine tumors. Kerr SE, Schnabel CA, Sullivan PS, Zhang Y, Huang VJ, Erlander MG, Brachtel EF, Dry SM. Mod Pathol. 2013 Jul 12. doi: 10.1038/modpathol.2013.105. View abstract here

Abdominal imaging can misdiagnose submassive hepatic necrosis as cirrhosis in acute liver failure. Kim AI, Han SH, Tran DT, Sullivan P, Lassman C, Raman S, Zimmerman P, Chin EE. Clin Transplant. 2013 May;27(3):E339-45. doi: 10.1111/ctr.12123. Epub 2013 May 6. View abstract here

Hints to the diagnosis of mixed acinar-endocrine carcinoma on pancreatic fine-needle aspiration: avoiding a potential diagnostic pitfall. Sullivan PS, Clebanoff JL, Hirschowitz SL. Acta Cytol. 2013;57(3):296-302. doi: 10.1159/000343683. Epub 2013 Apr 25. View abstract here

Multisite validation study to determine performance characteristics of a 92-gene molecular cancer classifier. Kerr SE, Schnabel CA, Sullivan PS, Zhang Y, Singh V, Carey B, Erlander MG, Highsmith WE, Dry SM, Brachtel EF. Clin Cancer Res. 2012 Jul 15;18(14):3952-60. doi: 10.1158/1078-0432.CCR-12-0920. Epub 2012 May 30. View abstract here

Solid pseudopapillary neoplasm, pancreas type, presenting as a primary ovarian neoplasm. Stoll LM, Parvataneni R, Johnson MW, Gui D, Dorigo O, Sullivan P. Hum Pathol. 2012 Aug;43(8):1339-43. doi: 10.1016/j.humpath.2011.12.018. Epub 2012 Apr 24. View abstract here

Expression of thyroid transcription factor-1 in normal endometrium is associated with risk of endometrial cancer development. Sullivan PS, Maresh EL, Seligson DB, Habeeb O, Wadehra M, Goodglick L, Dorigo O. Mod Pathol. 2012 Aug;25(8):1140-8. doi: 10.1038/modpathol.2012.64. Epub 2012 Mar 30. View abstract here

PubMed: Peggy Sullivan


Teitell, Michael, MD, PhD

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. Nature. 2014 May 14. doi: 10.1038/nature13264.

Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. Pate KT, Stringari C, Sprowl-Tanio S, Wang K, TeSlaa T, Hoverter NP, McQuade MM, Garner C, Digman MA, Teitell MA, Edwards RA, Gratton E, Waterman ML. EMBO J. 2014 May 13. pii: e201488598.

Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome. Klein S, Lee H, Ghahremani S, Kempert P, Ischander M, Teitell MA, Nelson SF, Martinez-Agosto JA. J Med Genet. 2014 May;51(5):294-302. doi: 10.1136/jmedgenet-2013-101943. Epub 2014 Mar 27.

Pulsed laser activated cell sorting with three dimensional sheathless inertial focusing. Chen Y, Chung AJ, Wu TH, Teitell MA, Di Carlo D, Chiou PY. Small. 2014 May;10(9):1746-51. doi: 10.1002/smll.201302885. Epub 2014 Feb 17.

3D pulsed laser-triggered high-speed microfluidic fluorescence-activated cell sorter. Chen Y, Wu TH, Kung YC, Teitell MA, Chiou PY. Analyst. 2013 Nov 12;138(24):7308-15. doi: 10.1039/c3an01266b.

The other genome: mitochondrial DNA and protection from experimental colitis. Boone DL, Teitell MA. Gastroenterology. 2013 Nov;145(5):933-5. doi: 10.1053/j.gastro.2013.09.034. Epub 2013 Sep 21. View abstract here

Quantification of biomass and cell motion in human pluripotent stem cell colonies. Zangle TA, Chun J, Zhang J, Reed J, Teitell MA. Biophys J. 2013 Aug 6;105(3):593-601. doi: 10.1016/j.bpj.2013.06.041. View abstract here

Quantifying biomass changes of single CD8+ T cells during antigen specific cytotoxicity. Zangle TA, Burnes D, Mathis C, Witte ON, Teitell MA. PLoS One. 2013 Jul 23;8(7):e68916. doi: 10.1371/journal.pone.0068916. Print 2013. View abstract here

3D pulsed laser-triggered high-speed microfluidic fluorescence-activated cell sorter. Chen Y, Wu TH, Kung YC, Teitell MA, Chiou PY. Analyst. 2013 Jul 11. View abstract here

Electrical Impedance Monitoring of Photothermal Porated Mammalian Cells. Yamane D, Wu YC, Wu TH, Toshiyoshi H, Teitell MA, Chiou PY. J Lab Autom. 2013 Jun 24. View abstract here

Detection of mRNA in living cells by double-stranded locked nucleic acid probes. Riahi R, Dean Z, Wu TH, Teitell MA, Chiou PY, Zhang DD, Wong PK. Analyst. 2013 Jun 17. View abstract here

Thoracoabdominal wall defect with complete ectopia cordis and gastroschisis: a case report and review of the literature. Pepper MA, Fishbein GA, Teitell MA. Pediatr Dev Pathol. 2013 May 20. View abstract here

A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dabir DV, Hasson SA, Setoguchi K, Johnson ME, Wongkongkathep P, Douglas CJ, Zimmerman J, Damoiseaux R, Teitell MA, Koehler CM. Dev Cell. 2013 Apr 15;25(1):81-92. doi: 10.1016/j.devcel.2013.03.006. View abstract here

Rapidly quantifying drug sensitivity of dispersed and clumped breast cancer cells by mass profiling. Chun J, Zangle TA, Kolarova T, Finn RS, Teitell MA, Reed J. Analyst. 2012 Dec 7;137(23):5495-8. doi: 10.1039/c2an36058f. Epub 2012 Oct 11. View abstract here

Nanoblade delivery and incorporation of quantum dot conjugates into tubulin networks in live cells. Xu J, Teslaa T, Wu TH, Chiou PY, Teitell MA, Weiss S. Nano Lett. 2012 Nov 14;12(11):5669-72. doi: 10.1021/nl302821g. Epub 2012 Nov 5. View abstract here

Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal. Zhang J, Nuebel E, Daley GQ, Koehler CM, Teitell MA. Cell Stem Cell. 2012 Nov 2;11(5):589-95. doi: 10.1016/j.stem.2012.10.005. View abstract here

PNPASE and RNA trafficking into mitochondria. Wang G, Shimada E, Koehler CM, Teitell MA. Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):998-1007. doi: 10.1016/j.bbagrm.2011.10.001. Epub 2011 Oct 13. View abstract here

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Graham NA, Tahmasian M, Kohli B, Komisopoulou E, Zhu M, Vivanco I, Teitell MA, Wu H, Ribas A, Lo RS, Mellinghoff IK, Mischel PS, Graeber TG. Mol Syst Biol. 2012 Jun 26;8:589. doi: 10.1038/msb.2012.20. View abstract here

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells. Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA. Nat Protoc. 2012 May 10;7(6):1068-85. doi: 10.1038/nprot.2012.048. View abstract here

Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter. Wu TH, Chen Y, Park SY, Hong J, Teslaa T, Zhong JF, Di Carlo D, Teitell MA, Chiou PY. Lab Chip. 2012 Apr 7;12(7):1378-83. doi: 10.1039/c2lc21084c. Epub 2012 Feb 24. View abstract here

Correcting human mitochondrial mutations with targeted RNA import. Wang G, Shimada E, Zhang J, Hong JS, Smith GM, Teitell MA, Koehler CM. Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4840-5. doi: 10.1073/pnas.1116792109. Epub 2012 Mar 12. View abstract here

PubMed: Michael Teitell


Tidball, James, PhD

Age-related loss of nitric oxide synthase in skeletal muscle causes reductions in calpain S-nitrosylation that increase myofibril degradation and sarcopenia. Samengo G, Avik A, Fedor B, Whittaker D, Myung KH, Wehling-Henricks M, Tidball JG. Aging Cell. 2012 Dec;11(6):1036-45. doi: 10.1111/acel.12003. Epub 2012 Oct 4. View abstract here

IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration. Deng B, Wehling-Henricks M, Villalta SA, Wang Y, Tidball JG. J Immunol. 2012 Oct 1;189(7):3669-80. Epub 2012 Aug 29. View abstract here

p38y activity is required for maintenance of slow skeletal muscle size. Foster WH, Tidball JG, Wang Y. Muscle Nerve. 2012 Feb;45(2):266-73. doi: 10.1002/mus.22289. View abstract here

PubMed: James Tidball


Tontonoz, Peter, MD, PhD

Palmoplantar Keratoderma along with Neuromuscular and Metabolic Phenotypes in Slurp1-Deficient Mice. Adeyo O, Allan BB, Barnes RH 2nd, Goulbourne CN, Tatar A, Tu Y, Young LC, Weinstein MM, Tontonoz P, Fong LG, Beigneux AP, Young SG. J Invest Dermatol. 2014 Jun;134(6):1589-98. doi: 10.1038/jid.2014.19. Epub 2014 Jan 17.

Liver X receptors in lipid metabolism: opportunities for drug discovery. Hong C, Tontonoz P. Nat Rev Drug Discov. 2014 May 16. doi: 10.1038/nrd4280. [Epub ahead of print]

The GPIHBP1-LPL Complex Is Responsible for the Margination of Triglyceride-Rich Lipoproteins in Capillaries. Goulbourne CN, Gin P, Tatar A, Nobumori C, Hoenger A, Jiang H, Grovenor CR, Adeyo O, Esko JD, Goldberg IJ, Reue K, Tontonoz P, Bensadoun A, Beigneux AP, Young SG, Fong LG. Cell Metab. 2014 May 6;19(5):849-60. doi: 10.1016/j.cmet.2014.01.017. Epub 2014 Apr 10.

The macrophage lipopolysaccharide binding protein gene is an LXR target that promotes macrophage survival and atherosclerosis. Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. J Lipid Res. 2014 Mar 26.

Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation. Goddard LM, Murphy TJ, Org T, Enciso JM, Hashimoto-Partyka MK, Warren CM, Domigan CK, McDonald AI, He H, Sanchez LA, Allen NC, Orsenigo F, Chao LC, Dejana E, Tontonoz P, Mikkola HK, Iruela-Arispe ML. Cell. 2014 Jan 30;156(3):549-62. doi: 10.1016/j.cell.2013.12.025.

LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition. Rong X, Albert CJ, Hong C, Duerr MA, Chamberlain BT, Tarling EJ, Ito A, Gao J, Wang B, Edwards PA, Jung ME, Ford DA, Tontonoz P. Cell Metab. 2013 Nov 5;18(5):685-97. doi: 10.1016/j.cmet.2013.10.002.

MafB promotes atherosclerosis by inhibiting foam-cell apoptosis. Hamada M, Nakamura M, Tran MT, Moriguchi T, Hong C, Ohsumi T, Dinh TT, Kusakabe M, Hattori M, Katsumata T, Arai S, Nakashima K, Kudo T, Kuroda E, Wu CH, Kao PH, Sakai M, Shimano H, Miyazaki T, Tontonoz P, Takahashi S. Nat Commun. 2014;5:3147. doi: 10.1038/ncomms4147.

Reciprocal regulation of hepatic and adipose lipogenesis by liver x receptors in obesity and insulin resistance. Beaven SW, Matveyenko A, Wroblewski K, Chao L, Wilpitz D, Hsu TW, Lentz J, Drew B, Hevener AL, Tontonoz P. Cell Metab. 2013 Jul 2;18(1):106-17. doi: 10.1016/j.cmet.2013.04.021. View abstract here

Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling. Csaki LS, Dwyer JR, Fong LG, Tontonoz P, Young SG, Reue K. Prog Lipid Res. 2013 Jul;52(3):305-16. doi: 10.1016/j.plipres.2013.04.001. Epub 2013 Apr 17. View abstract here

The nuclear receptor LXRα controls the functional specialization of splenic macrophages. A-Gonzalez N, Guillen JA, Gallardo G, Diaz M, de la Rosa JV, Hernandez IH, Casanova-Acebes M, Lopez F, Tabraue C, Beceiro S, Hong C, Lara PC, Andujar M, Arai S, Miyazaki T, Li S, Corbi AL, Tontonoz P, Hidalgo A, Castrillo A. Nat Immunol. 2013 Jun 16. doi: 10.1038/ni.2622 View abstract here

Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor. Zhang L, Xu M, Scotti E, Chen ZJ, Tontonoz P. J Lipid Res. 2013 May;54(5):1410-20. doi: 10.1194/jlr.M035774. Epub 2013 Feb 18. View abstract here

IDOL Stimulates Clathrin-Independent Endocytosis and Multivesicular Body-Mediated Lysosomal Degradation of the Low-Density Lipoprotein Receptor. Scotti E, Calamai M, Goulbourne CN, Zhang L, Hong C, Lin RR, Choi J, Pilch PF, Fong LG, Zou P, Ting AY, Pavone FS, Young SG, Tontonoz P. Mol Cell Biol. 2013 Apr;33(8):1503-14. doi: 10.1128/MCB.01716-12. Epub 2013 Feb 4. View abstract here

Adipose Subtype-Selective Recruitment of TLE3 or Prdm16 by PPARγ Specifies Lipid Storage versus Thermogenic Gene Programs. Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P. Cell Metab. 2013 Mar 5;17(3):423-35. doi: 10.1016/j.cmet.2013.01.016. View abstract here

Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice. Chao LC, Soto E, Hong C, Ito A, Pei L, Chawla A, Conneely OM, Tangirala RK, Evans RM, Tontonoz P. J Lipid Res. 2013 Mar;54(3):806-15. doi: 10.1194/jlr.M034157. Epub 2013 Jan 3. View abstract here

Both K63 and K48 Ubiquitin Linkages Signal Lysosomal Degradation of the LDL Receptor. Zhang L, Xu M, Scotti E, Chen ZJ, Tontonoz P. J Lipid Res. 2013 Feb 18. View abstract here

Vestigial-like 3 is an inhibitor of adipocyte differentiation. Halperin DS, Pan C, Lusis AJ, Tontonoz P. J Lipid Res. 2013 Feb;54(2):473-81. doi: 10.1194/jlr.M032755. Epub 2012 Nov 13. View abstract here

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, Reue K, Spencer MJ, Newgard CB, Tontonoz P. J Lipid Res. 2012 Dec;53(12):2610-9. doi: 10.1194/jlr.M029355. Epub 2012 Oct 1. View abstract here

Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. Zhang L, Reue K, Fong LG, Young SG, Tontonoz P. Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2541-6. doi: 10.1161/ATVBAHA.112.250571. Epub 2012 Aug 30. View abstract here

LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice. Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, Tontonoz P. J Lipid Res. 2012 Jun;53(6):1126-33. doi: 10.1194/jlr.M022061. Epub 2012 Mar 26. View abstract here

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR. Calkin AC, Tontonoz P. Nat Rev Mol Cell Biol. 2012 Mar 14;13(4):213-24. doi: 10.1038/nrm3312. View abstract here

Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. Weinstein MM, Goulbourne CN, Davies BS, Tu Y, Barnes RH 2nd, Watkins SM, Davis R, Reue K, Tontonoz P, Beigneux AP, Fong LG, Young SG. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):230-5. doi: 10.1161/ATVBAHA.111.241406. Epub 2011 Dec 15. View abstract here

SIRT1 regulation-it ain't all NAD. Chao LC, Tontonoz P. Mol Cell. 2012 Jan 13;45(1):9-11. doi: 10.1016/j.molcel.2011.12.017. View abstract here

Coordinate regulation of neutrophil homeostasis by liver X receptors in mice. Hong C, Kidani Y, A-Gonzalez N, Phung T, Ito A, Rong X, Ericson K, Mikkola H, Beaven SW, Miller LS, Shao WH, Cohen PL, Castrillo A, Tontonoz P, Bensinger SJ. J Clin Invest. 2012 Jan 3;122(1):337-47. doi: 10.1172/JCI58393. Epub 2011 Dec 12. View abstract here

The number of x chromosomes causes sex differences in adiposity in mice. Chen X, McClusky R, Chen J, Beaven SW, Tontonoz P, Arnold AP, Reue K. PLoS Genet. 2012;8(5):e1002709. doi: 10.1371/journal.pgen.1002709. Epub 2012 May 10. View abstract here

PubMed: Peter Tontonoz


Trelease, Robert, PhD

Transforming clinical imaging and 3D data for virtual reality learning objects: HTML5 and mobile devices implementation. Trelease RB, Nieder GL. Anat Sci Educ. 2012 Dec 4. doi: 10.1002/ase.1330. View abstract here

PubMed: Robert Trelease


Vinters, Harry, MD


Clinical Predictors of Severe Cerebral Amyloid Angiopathy and Influence of APOE Genotype in Persons With Pathologically Verified Alzheimer Disease. Ringman JM, Sachs MC, Zhou Y, Monsell SE, Saver JL, Vinters HV. JAMA Neurol. 2014 May 5. doi: 10.1001/jamaneurol.2014.681. [Epub ahead of print]

Sympathetic Nerve Fibers in Human Cervical and Thoracic Vagus Nerves. Seki A, Green HR, Lee TD, Hong L, Tan J, Vinters HV, Chen PS, Fishbein MC. Heart Rhythm. 2014 Apr 23. pii: S1547-5271(14)00460-3. doi: 10.1016/j.hrthm.2014.04.032.

The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings. Shabihkhani M, Lucey GM, Wei B, Mareninov S, Lou JJ, Vinters HV, Singer EJ, Cloughesy TF, Yong WH. Clin Biochem. 2014 Mar;47(4-5):258-66. doi: 10.1016/j.clinbiochem.2014.01.002. Epub 2014 Jan 12

Practical utility of amyloid and FDG-PET in an academic dementia center. Sánchez-Juan P, Ghosh PM, Hagen J, Gesierich B, Henry M, Grinberg LT, O'Neil JP, Janabi M, Huang EJ, Trojanowski JQ, Vinters HV, Gorno-Tempini M, Seeley WW, Boxer AL, Rosen HJ, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD. Neurology. 2014 Jan 21;82(3):230-8. doi: 10.1212/WNL.0000000000000032. Epub 2013 Dec 18.

Neuropathologic correlates of trial-related instruments for Alzheimer's disease. Cummings JL, Ringman J, Vinters HV. Am J Neurodegener Dis. 2014 Mar 28;3(1):45-9. eCollection 2014.

Isolated choroid plexus granulomas: initial presentation of neurosarcoidosis? Kallen ME, Boon-Unge K, Yong WH, Pope WB, Frazee JG, Vinters HV. Can J Neurol Sci. 2014 Jan;41(1):112-4.

Neuropathologic analysis of hematomas evacuated from patients with spontaneous intracerebral hemorrhage. Dye JA, Rees G, Yang I, Vespa PM, Martin NA, Vinters HV. Neuropathology. 2013 Dec 20. doi: 10.1111/neup.12089. [Epub ahead of print]

Lenin's malady--reply. Vinters HV, Mackowiak PA. Hum Pathol. 2013 Dec;44(12):2869-70. doi: 10.1016/j.humpath.2013.06.021. Epub 2013 Oct 22.

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology, Alpérovitch A, Boland A, Delépoine M, Dubois B, Duron E, Epelbaum J, Van Cauwenberghe C, Engelborghs S, Vandenberghe R, De Deyn PP, Ferri R, Romano C, Caltagirone C, Orfei MD, Ciaramella A, Scarpini E, Fenoglio C, Siciliano G, Bonuccelli U, Bagnoli S, Bracco L, Bessi V, Cecchetti R, Bastiani P, Squassina A, Seripa D, Frank-García A, Sastre I, Blesa R, Alcolea D, Suárez-Clavet M, Sánchez-Juan P, Muñoz Fernandez C, Aladro Benito Y, Thonberg H, Forshell C, Lilius L, Kinhult-Ståhlbom A, Giedraitis V, Kilander L, Brundin RM, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Solfrizzi V, Frisardi V, Ott J, Carney RM, Mash DC, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barmada MM, Barnes LL, Beach TG, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burk JR, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chibnik LB, Chui HC, Clark DG, Corneveaux J, Cribbs DG, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilman S, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Karydas A, Kauwe JS, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, Kramer P, LaFerla FM, Lah JJ, Levernez JB, Levey AI, Li G, Lieberman AP, Lyketsos CG, Mack WJ, Marson DC, Martiniuk F, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Olichney JM, Pankratz VS, Parasi JE, Peskind E, Peterson RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Yu CE, Barber R, Au R, Wolf PA, Beiser A, Debette S, Yang Q, Weinstein G, Johnson AD, Wang J, Uitterlinden AG, Rivadeneira F, Koudstgaal PJ, Longstreth WT Jr, Becker JT, Kuller LH, Lumley T, Rice K, Garcia M, Aspelund T, Marksteiner JJ, Dal-Bianco P, Töglhofer AM, Freudenberger P, Ransmayr G, Benke T, Toeglhofer AM, Bressler J, Breteler MM, Fornage M, Hernández I, Rosende Roca M, Ana Mauleón M, Alegrat M, Ramírez-Lorca R, González-Perez A, Chapman J, Stretton A, Morgan A, Kehoe PG, Medway C, Lord J, Turton J, Hooper NM, Vardy E, Warren JD, Schott JM, Uphill J, Ryan N, Rossor M, Ben-Shlomo Y, Makrina D, Gkatzima O, Lupton M, Koutroumani M, Avramidou D, Germanou A, Jessen F, Riedel-Heller S, Dichgans M, Heun R, Kölsch H, Schürmann B, Herold C, Lacour A, Drichel D, Hoffman P, Kornhuber J, Gu W, Feulner T, van den Bussche H, Lawlor B, Lynch A, Mann D, Smith AD, Warden D, Wilcock G, Heuser I, Wiltgang J, Frölich L, Hüll M, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Jöckel KH, Klopp N, Wichmann HE, Dickson DW, Graff-Radford NR, Ma L, Bisceglio G, Fisher E, Warner N, Pickering-Brown S. Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27.

TREM2 and neurodegenerative disease. Reitz C, Mayeux R; Alzheimer's Disease Genetics Consortium. N Engl J Med. 2013 Oct 17;369(16):1564-5. doi: 10.1056/NEJMc1306509#SA1.

Pacemaker GABA synaptic activity may contribute to network synchronization in pediatric cortical dysplasia. Cepeda C, Chen JY, Wu JY, Fisher RS, Vinters HV, Mathern GW, Levine MS. Neurobiol Dis. 2013 Oct 10. doi:pii: S0969-9961(13)00274-X. 10.1016/j.nbd.2013.10.001. View abstract here

Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes. Zheng L, Vinters HV, Mack WJ, Zarow C, Ellis WG, Chui HC. Stroke. 2013 Oct;44(10):2835-41. doi: 10.1161/STROKEAHA.113.001945. Epub 2013 Jul 25. View abstract here

A swine model to analyze arterial structural changes induced by mechanical thrombectomy. Yuki I, Kan I, Golshan A, Sohn J, Murayama Y, Vinters HV, Viñuela F. AJNR Am J Neuroradiol. 2013 Aug;34(8):E87-90. doi: 10.3174/ajnr.A3221. Epub 2012 Jul 12. View abstract here

Surgical pathology of epilepsy-associated non-neoplastic cerebral lesions: a brief introduction with special reference to hippocampal sclerosis and focal cortical dysplasia. Miyata H, Hori T, Vinters HV. Neuropathology. 2013 Aug;33(4):442-58. doi: 10.1111/neup.12028. Epub 2013 Mar 27. View abstract here

A shift in microglial β-amyloid binding in Alzheimer's disease is associated with cerebral amyloid angiopathy. Zabel M, Schrag M, Crofton A, Tung S, Beaufond P, Van Ornam J, Dininni A, Vinters HV, Coppola G, Kirsch WM. Brain Pathol. 2013 Jul;23(4):390-401. doi: 10.1111/bpa.12005. Epub 2012 Nov 28. View abstract here

Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage. Mareninov S, De Jesus J, Sanchez DE, Kay AB, Wilson RW, Babic I, Chen W, Telesca D, Lou JJ, Mirsadraei L, Gardner TP, Khanlou N, Vinters HV, Shafa BB, Lai A, Liau LM, Mischel PS, Cloughesy TF, Yong WH. J Neurooncol. 2013 Jul;113(3):365-73. doi: 10.1007/s11060-013-1135-1. Epub 2013 May 3. View abstract here

Simulated biomechanical responses at a curved arterial segment after Wingspan Stent deployment in swine. Fujimoto M, Shobayashi Y, Tateshima S, Vinters HV, Viñuela F. Neurol Res. 2013 Jul;35(6):631-5. doi: 10.1179/1743132813Y.0000000180. Epub 2013 Feb 18. View abstract here

Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein. Sarafian TA, Ryan CM, Souda P, Masliah E, Kar UK, Vinters HV, Mathern GW, Faull KF, Whitelegge JP, Watson JB. PLoS One. 2013 May 7;8(5):e63557. doi: 10.1371/journal.pone.0063557. View abstract here

Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response. Owens GC, Huynh MN, Chang JW, McArthur DL, Hickey MJ, Vinters HV, Mathern GW, Kruse CA. J Neuroinflammation. 2013 May 2;10:56. doi: 10.1186/1742-2094-10-56. View abstract here

Characterization of Arterial Thrombus Composition by Magnetic Resonance Imaging in a Swine Stroke Model. Fujimoto M, Salamon N, Mayor F, Yuki I, Takemoto K, Vinters HV, Viñuela F. Stroke. 2013 Mar 14. View abstract here

Time to pediatric epilepsy surgery is related to disease severity and nonclinical factors. Baca CB, Vickrey BG, Vassar S, Hauptman JS, Dadour A, Oh T, Salamon N, Vinters HV, Sankar R, Mathern GW. Neurology. 2013 Mar 6. View abstract here

Vessels of Stone: Lenin's "Circulatory Disturbance of the Brain" Vinters H, Lurie L, Mackowiak PA. Hum Pathol. 2013 Feb 18. doi:pii: S0046-8177(12)00445-5. 10.1016/j.humpath.2012.11.017. View abstract here

Primary central nervous system histiocytic sarcoma presenting as a postradiation sarcoma: case report and literature review. Wu W, Tanrivermis Sayit A, Vinters HV, Pope W, Mirsadraei L, Said J. Hum Pathol. 2013 Jan 26. doi:pii: S0046-8177(12)00424-8. 10.1016/j.humpath.2012.11.002. View abstract here

Biomechanical responses after Wingspan Stent deployment in swine ascending pharyngeal artery. Fujimoto M, Shobayashi Y, Tateshima S, Vinters HV, Viñuela F. Neurol Res. 2013 Jan;35(1):90-4. doi: 10.1179/1743132812Y.0000000119. View abstract here

Acromegaly due to an ectopic pituitary adenoma in the clivus: case report and review of literature. Appel JG, Bergsneider M, Vinters H, Salamon N, Wang MB, Heaney AP. Pituitary. 2012 Dec;15 Suppl 1:S53-6. doi: 10.1007/s11102-011-0345-9. View abstract here

STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Nobuta H, Ghiani CA, Paez PM, Spreuer V, Dong H, Korsak RA, Manukyan A, Li J, Vinters HV, Huang EJ, Rowitch DH, Sofroniew MV, Campagnoni AT, de Vellis J, Waschek JA. Ann Neurol. 2012 Nov;72(5):750-65. doi: 10.1002/ana.23670. Epub 2012 Aug 31. View abstract here

Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses. Henkins KM, Sokolow S, Miller CA, Vinters HV, Poon WW, Cornwell LB, Saing T, Gylys KH. Brain Pathol. 2012 Nov;22(6):826-33. doi: 10.1111/j.1750-3639.2012.00598.x. Epub 2012 May 23. View abstract here

Pediatric epilepsy surgery: long-term 5-year seizure remission and medication use. Hauptman JS, Pedram K, Sison CA, Sankar R, Salamon N, Vinters HV, Mathern GW. Neurosurgery. 2012 Nov;71(5):985-93. doi: 10.1227/NEU.0b013e31826cdd5a. View abstract here

Intimal thickening of meningeal arteries after serial corticectomies for Rasmussen encephalitis. Wagner AS, Yin NS, Tung S, Mathern GW, Vinters HV. Hum Pathol. 2012 Aug;43(8):1308-13. doi: 10.1016/j.humpath.2011.10.011. Epub 2012 Mar 7. View abstract here

Postmortem 3-D Brain Hemisphere Cortical Tau and Amyloid-β Pathology Mapping and Quantification as a Validation Method of Neuropathology Imaging. Smid LM, Kepe V, Vinters HV, Bresjanac M, Toyokuni T, Satyamurthy N, Wong KP, Huang SC, Silverman DH, Miller K, Small GW, Barrio JR. J Alzheimers Dis. 2013 Apr 8. View abstract here

De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Akhavan D, Pourzia AL, Nourian AA, Williams KJ, Nathanson D, Babic I, Villa GR, Tanaka K, Nael A, Yang H, Dang J, Vinters HV, Yong WH, Flagg M, Tamanoi F, Sasayama T, James CD, Kornblum HI, Cloughesy TF, Cavenee WK, Bensinger SJ, Mischel PS. Cancer Discov. 2013 Mar 27. View abstract here

AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly. Sokolow S, Henkins KM, Bilousova T, Miller CA, Vinters HV, Poon W, Cole GM, Gylys KH. Neurobiol Aging. 2012 Aug;33(8):1545-55. doi: 10.1016/j.neurobiolaging.2011.05.011. Epub 2011 Jul 7. View abstract here

Mutations in the RNA exosome component gene EXOSC3 cause pontocerebellar hypoplasia and spinal motor neuron degeneration. Wan J, Yourshaw M, Mamsa H, Rudnik-Schöneborn S, Menezes MP, Hong JE, Leong DW, Senderek J, Salman MS, Chitayat D, Seeman P, von Moers A, Graul-Neumann L, Kornberg AJ, Castro-Gago M, Sobrido MJ, Sanefuji M, Shieh PB, Salamon N, Kim RC, Vinters HV, Chen Z, Zerres K, Ryan MM, Nelson SF, Jen JC. Nat Genet. 2012 Apr 29;44(6):704-8. doi: 10.1038/ng.2254. View abstract here

Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. Engel J Jr, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K; Early Randomized Surgical Epilepsy Trial (ERSET) Study Group. JAMA. 2012 Mar 7;307(9):922-30. doi: 10.1001/jama.2012.220. View abstract here

Isolation of synaptic terminals from Alzheimer's disease cortex. Sokolow S, Henkins KM, Williams IA, Vinters HV, Schmid I, Cole GM, Gylys KH. Cytometry A. 2012 Mar;81(3):248-54. doi: 10.1002/cyto.a.22009. Epub 2011 Dec 28. View abstract here

Heterotopic Purkinje cells in ataxia-telangiectasia. Bottini AR, Gatti RA, Wirenfeldt M, Vinters HV. Neuropathology. 2012 Feb;32(1):23-9. doi: 10.1111/j.1440-1789.2011.01210.x. Epub 2011 Mar 29. View abstract here

Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex. Arold S, Sullivan P, Bilousova T, Teng E, Miller CA, Poon WW, Vinters HV, Cornwell LB, Saing T, Cole GM, Gylys KH. Acta Neuropathol. 2012 Jan;123(1):39-52. doi: 10.1007/s00401-011-0892-1. Epub 2011 Oct 22. View abstract here

Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex. Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, Gylys KH. Neurobiol Dis. 2012 Jan;45(1):381-7. doi: 10.1016/j.nbd.2011.08.027. Epub 2011 Sep 3. View abstract here

Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex. Cepeda C, André VM, Hauptman JS, Yamazaki I, Huynh MN, Chang JW, Chen JY, Fisher RS, Vinters HV, Levine MS, Mathern GW. Neurobiol Dis. 2012 Jan;45(1):310-21. doi: 10.1016/j.nbd.2011.08.015. Epub 2011 Aug 23. View abstract here

Pathologic lesions in neurodegenerative diseases. Thompson PM, Vinters HV. Prog Mol Biol Transl Sci. 2012;107:1-40. doi: 10.1016/B978-0-12-385883-2.00009-6. View abstract here

PubMed: Harry Vinters


Wadehra, Madhuri, PhD

Rationale and preclinical efficacy of a novel anti-EMP2 antibody for the treatment of invasive breast cancer. Fu M, Maresh EL, Helguera GF, Kiyohara M, Qin Y, Ashki N, Daniels-Wells TR, Aziz N, Gordon LK, Braun J, Elshimali Y, Soslow RA, Penichet ML, Goodglick L, Wadehra M. Mol Cancer Ther. 2014 Apr;13(4):902-15. doi: 10.1158/1535-7163.MCT-13-0199. Epub 2014 Jan 21.

Peroxynitrite upregulates angiogenic factors VEGF-A, BFGF, and HIF-1α in human corneal limbal epithelial cells. Ashki N, Chan AM, Qin Y, Wang W, Kiyohara M, Lin L, Braun J, Wadehra M, Gordon LK. Invest Ophthalmol Vis Sci. 2014 Mar 19;55(3):1637-46. doi: 10.1167/iovs.13-12410.

Could pericytic mimicry represent another type of melanoma cell plasticity with embryonic properties? Lugassy C, Péault B, Wadehra M, Kleinman HK, Barnhill RL. Pigment Cell Melanoma Res. 2013 Jun 22. doi: 10.1111/pcmr.12120. View abstract here

EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF. Gordon LK, Kiyohara M, Fu M, Braun J, Dhawan P, Chan A, Goodglick L, Wadehra M. Oncogene. 2013 Jan 21. doi: 10.1038/onc.2012.622 View abstract here

Pilot study on "pericytic mimicry" and potential embryonic/stem cell properties of angiotropic melanoma cells interacting with the abluminal vascular surface. Lugassy C, Wadehra M, Li X, Corselli M, Akhavan D, Binder SW, Péault B, Cochran AJ, Mischel PS, Kleinman HK, Barnhill RL. Cancer Microenviron. 2013 Apr;6(1):19-29. doi: 10.1007/s12307-012-0128-5. Epub 2012 Dec 29. View abstract here

Epithelial membrane protein 2 (EMP2) controls VEGF expression in ARPE-19 cells. Morales SA, Telander DG, Leon D, Forward K, Braun J, Wadehra M, Gordon LK. Invest Ophthalmol Vis Sci. 2013 Feb 25. doi:pii: iovs.12-11013v1. 10.1167/iovs.12-11013. View abstract here

Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments. Fu M, Brewer S, Olafsen T, Wu AM, Gordon LK, Said J, Braun J, Wadehra M. Mol Imaging Biol. 2013 Feb;15(1):68-78. doi: 10.1007/s11307-012-0558-y. View abstract here

Anti-EMP2 diabody blocks epithelial membrane protein 2 (EMP2) and FAK mediated collagen gel contraction in ARPE-19 cells. Morales SA, Telander DG, Mareninov S, Nagy A, Wadehra M, Braun J, Gordon LK. Exp Eye Res. 2012 Sep;102:10-6. doi: 10.1016/j.exer.2012.06.002. Epub 2012 Jun 19. View abstract here

Expression of thyroid transcription factor-1 in normal endometrium is associated with risk of endometrial cancer development. Sullivan PS, Maresh EL, Seligson DB, Habeeb O, Wadehra M, Goodglick L, Dorigo O. Mod Pathol. 2012 Aug;25(8):1140-8. doi: 10.1038/modpathol.2012.64. Epub 2012 Mar 30. View abstract here

PubMed: Madhuri Wadehra


Wang, Hanlin, MD, PhD

Substrate-free ultra-flexible organic field-effect transistors and five-stage ring oscillators. Zhang L, Wang H, Zhao Y, Guo Y, Hu W, Yu G, Liu Y. Adv Mater. 2013 Oct 11;25(38):5455-60. doi: 10.1002/adma.201300675. Epub 2013 Jun 21. View abstract here

Patients with nodular regenerative hyperplasia should be considered for hepatocellular carcinoma screening. Sood A, Cox GA 2nd, McWilliams JP, Wang HL, Saab S. Hepatol Res. 2013 Apr 17. doi: 10.1111/hepr.12136. View abstract here

Diagnostic utility of von Hippel-Lindau gene product, maspin, IMP3, and S100P in adenocarcinoma of the gallbladder. Shi J, Liu H, Wang HL, Prichard JW, Lin F. Hum Pathol. 2013 Apr;44(4):503-11. doi: 10.1016/j.humpath.2012.06.010. Epub 2012 Oct 15. View abstract here

Helicobacter pylori infection and colorectal carcinoma: is there a causal association? Tatishchev SF, Vanbeek C, Wang HL. J Gastrointest Oncol. 2012 Dec;3(4):380-5. doi: 10.3978/j.issn.2078-6891.2012.058. View abstract here

Smoothelin Expression in the Gastrointestinal Tract: Implication in Colonic Inertia. Chan OT, Chiles L, Levy M, Zhai J, Yerian LM, Xu H, Xiao SY, Soffer EE, Conklin JL, Dhall D, Kahn ME, Balzer BL, Amin MB, Wang HL. Appl Immunohistochem Mol Morphol. 2012 Oct 10. View abstract here

Colorectal carcinoma: Pathologic aspects. Fleming M, Ravula S, Tatishchev SF, Wang HL. J Gastrointest Oncol. 2012 Sep;3(3):153-73. doi: 10.3978/j.issn.2078-6891.2012.030. View abstract here

Utility of von Hippel-Lindau gene product, maspin, IMP3, and S100P in adenocarcinoma of the gallbladder. Shi J, Liu H, Wang HL, Prichard J, Lin F. Hum Pathol. 2013; 44:503-511. View abstract here

Role of cytolethal distending toxin in altered stool form and bowel phenotypes in a rat model of post-infectious irritable bowel syndrome. Pokkunuri V, Pimentel M, Morales W, Jee SR, Alpern J, Weitsman S, Marsh Z, Low K, Hwang L, Khoshini R, Barlow GM, Wang H, Chang C. J Neurogastroenterol Motil. 2012; 18:434-442. View abstract here

IMP3, NESP55, TTF-1 and CDX2 serve as an immunohistochemical panel in the distinction among small cell carcinoma, gastrointestinal carcinoid and pancreatic endocrine tumor metastasized to the liver. Denby KS, Briones AJ, Bourne PA, Spaulding BO, Lu D, Fischer-Colbrie R, Qu Z, Wang HL, Xu H. Appl Immunohistochem Mol Morphol. 2012; 20:573-579. View abstract here

Value of Islet 1 and PAX8 in identifying metastatic neuroendocrine tumors of pancreatic origin. Koo J, Mertens RB, Mirocha JM, Wang HL, Dhall D. Mod Pathol. 2012; 25:893-901. View abstract here

Use of IMP3, S100P and pVHL immunopanel to aid in the interpretation of bile duct biopsies with atypical histology or suspicious for malignancy. Schmidt MT, Himmelfarb EA, Shafi H, Lin F, Xu H, Wang HL. Appl Immunohistochem Mol Morphol. 2012; 20:478-487. View abstract here

Reevaluation and identification of the best immunohistochemical panel (pVHL, maspin, S100P, IMP-3) for ductal adenocarcinoma of the pancreas. Liu H, Shi J, Anandan V, Wang HL, Diehl D, Blansfield J, Gerhard G, Lin F. Arch Pathol Lab Med. 2012; 136:601-609. View abstract here

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M, Rotter JI, Wang HL, McGovern DP, Brown GD, Underhill DM. Science. 2012 Jun 8; 336(6086):1314-7. View abstract here

Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. Levy M, Trivedi A, Zhang J, Miles L, Mattis AN, Kim GE, Lassman C, Anders RA, Misdraji J, Yerian LM, Xu H, Dhall D, Wang HL. Hum Pathol. 2012; 43:695-701. View abstract here

Expression of von Hippel-Lindau gene product (pVHL) and S100P in cystic neoplasms of the pancreas - with an implication for their roles in tumorigenesis. Liu H, Shi J, Wang HL, Zhang J, Brown RE, Wilkerson M, Lin F. Ann Clin Lab Sci. 2012; 42:301-309. View abstract here

Ki-67 proliferative index predicts progression-free survival of patients with well-differentiated ileal neuroendocrine tumors. Dhall D, Mertens R, Bresee C, Parakh R, Wang HL, Li M, Dhall G, Colquhoun SD, Ines D, Chung F, Yu R, Nissen NN, Wolin E. Hum Pathol. 2012; 43:489-495. View abstract here

Diagnostic utility of PAX8, TTF-1 and napsin A for discriminating metastatic carcinoma from primary adenocarcinoma of the lung. Ye J, Hameed O, Findeis-Hosey JJ, Fan L, Li F, McMahon LA, Yang Q, Wang HL, Xu H. Biotechnic & Histochemistry. 2012; 87:30-34. View abstract here

Metastatic endometrial stromal sarcoma of the lung: importance of immunohistochemical staining, clinical history and imaging studies. Mentrikoski MJ, Zhao C, Zhang J, Wang HL, McMahon LA, Yang Q, Li F, Xu H. Biotechnic & Histochemistry. 2012; 87:35-39. View abstract here

Diagnostic utility of CD10 in benign and malignant extrahepatic bile duct lesions. Tretiakova M, Antic T, Westerhoff M, Mueller J, Himmelfarb EA, Wang HL, Xiao SY. Am J Surg Pathol. 2012; 36:101-108. View abstract here


PubMed: Hanlin Wang


Ziman, Alyssa, MD

The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions. Estcourt LJ, Heddle N, Kaufman R, McCullough J, Murphy MF, Slichter S, Wood EM, Stanworth SJ; Biomedical Excellence for Safer Transfusion Collaborative. Transfusion. 2013 Jul;53(7):1531-43. doi: 10.1111/trf.12058. Epub 2013 Jan 10. View abstract here

Is the 30-minute rule still applicable in the 21st century? Dumani D, Goldfinger D, Ziman A. Transfusion. 2013 Jun;53(6):1150-2. doi: 10.1111/trf.12220. View abstract here

Storage age of transfused red blood cells during liver transplantation and its intraoperative and postoperative effects. Chen J, Singhapricha T, Memarzadeh M, Ziman A, Yuan S, Hu KQ, Steadman RH, Busuttil RW, Xia VW. World J Surg. 2012 Oct;36(10):2436-42. doi: 10.1007/s00268-012-1691-0. View abstract here

The HI-STAR study: resource utilization and costs associated with serologic testing for antibody-positive patients at four United States medical centers. Mazonson P, Efrusy M, Santas C, Ziman A, Burner J, Roseff S, Vijayaraghavan A, Kaufman R. Transfusion. 2013 Apr 3. doi: 10.1111/trf.12176. View abstract here

Derivation of non-infectious envelope proteins from virions isolated from plasma negative for HIV antibodies. Vyas GN, Stoddart CA, Killian MS, Brennan TV, Goldberg T, Ziman A, Bryson Y. Biologicals. 2012 Jan;40(1):15-20. doi: 10.1016/j.biologicals.2011.11.005. Epub 2011 Dec 20.


PubMed: Alyssa Ziman