Research
Innovative thoracic surgery research at UCLA
UCLA's Division of Thoracic Surgery leads comprehensive research initiatives aimed at improving diagnosis, treatment, and outcomes for patients with thoracic diseases. The division emphasizes innovation, multidisciplinary collaboration, and patient-centered care.
Research focus areas
Thoracic oncology and immunotherapy
UCLA researchers are at the forefront of thoracic oncology, investigating the molecular and immunologic drivers of lung and esophageal cancers. Studies focus on tumor biology, immunotherapy responsiveness, and surgical decision-making to enhance patient outcomes.
Mesothelioma and pleural disease
The Comprehensive Mesothelioma Program at UCLA, established in 1997, offers advanced treatments such as lung-sparing surgery, targeted radiation, immunotherapy, and participation in clinical trials. The program emphasizes improving survival and quality of life for patients with malignant pleural mesothelioma.
Outcomes and health services research
Through data-driven investigations, UCLA researchers analyze surgical outcomes, quality metrics, and healthcare disparities. The aim is to improve thoracic surgery practices and ensure equitable access to high-quality care.
Cardiothoracic transplant and device research
UCLA is a leader in heart and lung transplantation research, focusing on innovations like ex vivo lung perfusion and advanced donor-lung preservation techniques to expand transplant access and improve patient outcomes.
Research facilities and labs
CORELAB (Cardiac Outcomes Research Laboratory)
CORELAB is dedicated to defining clinical outcomes and improving processes of care in cardiovascular surgery. The lab conducts national database analyses, evaluates quality metrics, and investigates disparities in thoracic care delivery.
Translational Thoracic Surgery Laboratory
Led by Dr. Bryan Burt, the laboratory translates innovative surgical techniques and treatments from bench to bedside, accelerating progress in biomarker discovery, regenerative tissue engineering, and understanding disease mechanisms
CASIT (Center for Advanced Surgical and Interventional Technology)
CASIT provides a state-of-the-art environment for surgical training, technology testing, and data integration. The center supports innovation in thoracic surgical techniques through simulation, robotics, and minimally invasive procedure development.
Related initiatives
- Early lung cancer detection: UCLA participates in national screening programs to enhance early detection strategies for lung cancer.
- Community engagement in research: Efforts are made to partner with community organizations to improve awareness and participation in thoracic clinical trials, aiming to reduce healthcare disparities.