National Center for Biotechnology Information Collections
View the lab's list of NCBI publications of biomedical and genomic information.
Selected Publications
- Lenis, T.L., Sarfare, S., Jiang, Z., Lloyd, M.B., Bok, D., and Radu, R.A.* (2017)
Complement Modulation in the Retinal Pigment Epithelium Rescues Photoreceptor Degeneration in a Mouse Model of Stargardt Disease. Natl. Acad. Sci. USA, 114(15):3987-3992; https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC5393232 PMCID:PMC5393232.
- Radu, R.A.*, Hu, J., Jiang, Z., and Bok, D. (2014)
Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells is Dependent on Complement Factor H Haplotype. Biol. Chem. 289: 9113-9120;
https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC3979386 PMCID:PMC3979386.
- Radu, R.A.*, Hu, J., Yuan, Q., Welch, D.L., Makshanoff, J., Lloyd, M., McMullen, S., Travis,G.H., and Bok, D. (2011)
Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration. Biol. Chem. 286(21): 18593-18601; https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC3099675 PMCID:PMC3099675.
- Radu, R.A., Yuan, Q., Hu, J., Peng, J.H., Lloyd, M., Nusinowitz, S. Bok, D., Travis, G.H., (2008)
Vitamin A Accelerated Accumulation of Lipofuscin Pigments in the RPE of a Mouse Model for ABCA4-mediated Retinal Dystrophies Following Vitamin A Supplementation. Ophthalmol. Vis. Sci. 49(9), 3821-3829;
https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC2851626 PMCID:PMC2851626.
- Radu, R.A., Han, Y., Bui, T.V., Nusinowitz, S., Bok, D., Lichter, J., Widder, K., Travis, G.H., Mata, N.L. (2005)
Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-based Retinal Diseases. Ophthalmol. Vis. Sci. 46, 4393-4401;
https://www.ncbi.nlm.nih.gov/pubmed/?term=16303925 PMID:16303925.
- Radu, R.A., Hu, J., Peng, J.H., Bok, D., Mata, N.L., Travis, G.H. (2008)
Retinal Pigment Epithelium-retinal G Protein Receptor-Opsin Mediates Light-dependent Translocation of all-trans-retinyl Esters for Synthesis of Visual Chromophore in Retinal Pigment Epithelial Cells. Biol. Chem. 283(28), 19730-19730;
https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC2443657 PMCID:PMC2443657.
- Mata, N.L., Ruiz, A., Radu, R.A., Bui, T.V., Travis, G.H. (2005)
Chicken Retinas Contain a Retinoid Isomerase Activity that Catalyzes the Direct Conversion of all-trans-retinol to 11-cis- Biochemistry 44, 11715-11721;
https://www.ncbi.nlm.nih.gov/pubmed/?term=16128572 PMID:16128572
- Radu, R.A., Mata, N.L., Bagla, A., and Travis, G.H. (2004)
Light Exposure Stimulates Formation of A2E Oxirane in a Mouse Model of Stargardt's Macular Degeneration. Natl. Acad. Sci. USA 101, 5928-5933;
https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC395900 PMCID:PMC395900.
- Radu, R.A., Mata, N.L., Nusinowitz, S., Liu, X., Sieving, P.A., and Travis, G.H. (2003)
Treatment with Isotretinoin Inhibits Lipofuscin Accumulation in a Mouse Model of Recessive Stargardt's Macular Degeneration. Natl. Acad. Sci. USA 100, 4742-4747;
https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC153626 PMCID:PMC153626.
- Mata, N.L., Radu, R.A., Clemmons, R.S., and Travis, G.H. (2002)
Isomerization and Oxidation of Vitamin A in Cone-dominant retinas: Evidence for a New Pathway that Mediates Regeneration of Visual Pigments in Daylight. Neuron 36, 69-80; https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC2851622 PMCID:PMC2851622.
