Help us answer some intriguing questions about the effect of stress on ulcerative colitis symptoms. Dr. Emeran A. Mayer, director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience (CNSR), Dr. Jenny Sauk, clinical director of the Center for Inflammatory Bowel Diseases, and Dr. Jonathan P. Jacobs, director of the Jacobs Laboratory, are conducting the UC Longitudinal Study to identify novel brain-gut-microbiome pathways that cause symptoms in IBD patients. This research study is to improve our understanding of IBD and its underlying cause.
We will use magnetic resonance imaging (MRI) to observe differences in the brain between people diagnosed with UC compared to healthy controls. We will also collect other measures such as thermal sensitivity and blood and stool samples, to be able to make biological connections associated with the subject groups. By doing this study, we hope to enhance our knowledge on IBD in order to keep the field moving in the right direction and becoming one step closer to discovering effective treatments.
Participants must be:
Compensation:
For further details please call Miriam Dvorsky at 310-206-3778 or mdvorsky@mednet.ucla.edu or Hyo Jin Ryu at 310-825-7206.
UCLA IRB Approved IRB# 18-000470 Committee: Medical IRB 3 Approval Date: 4/25/2018 through 4/24/2019
Do you suffer from abdominal pain, constipation, and/or diarrhea? Have you ever been told you have irritable bowel syndrome (IBS)? If so, and you are 18 years or older, you may qualify to participate in a UCLA research study that involves free nutrition sessions with a skilled IBS-specializing dietitian.
If so, we invite you to participate in brain imaging research at the G. Oppenheimer Center for Neurobiology of Stress and Resilience.
To participate, you must be:
This study is conducted by Lin Chang, MD, G. Oppenheimer Center for Neurobiology of Stress and Resilience.
If interested, please contact Nafeesa Islam at 310-206-1656 or nislam@mednet.ucla.edu
Protocol ID: IRB #10-000934 UCLA IRB Approval Date: 7/11/2018 through 7/10/2019 Committee: Medical IRB 1
Do you suffer from abdominal pain, constipation and/or diarrhea? Have you ever been told that you have irritable bowel syndrome or IBS? If so, you may qualify to participate in a research study involving a treatment program designed to target stress in patients with irritable bowel syndrome (IBS).
To participate, you must be:
Eligible participants will:
Compensation:
This study is conducted by Lin Chang, MD, G. Oppenheimer Center for Neurobiology of Stress and Resilience. If interested, please contact Nafeesa Islam at 310-206-1656 or nislam@mednet.ucla.edu
*Please note that confidentiality of emails cannot be guaranteed. Do not include sensitive information in your email if you choose to contact us by that method.
Protocol ID:IRB#18-000235 UCLA IRB Approved Approval Date: 7/17/2018 Through: 2/27/2019 Committee: Medical IRB 1
If so, we invite you to participate in brain imaging research at the G. Oppenheimer Center for Neurobiology of Stress and Resilience.
To participate, you must be:
Each visit will include the following:
Compensation:
Women: Earn up to $620 for completing all 5 visits over 12 months at 3 month intervals
Men: Earn up to $150 for a screening visit, an MRI, one stool and blood sample
This study is conducted by Emeran A. Mayer, MD, G. Oppenheimer Center for Neurobiology of Stress and Resilience.
If interested, please call Kimberly at 310-825-7217 or kimberlygonzalez@mednet.ucla.edu
Protocol ID: IRB #15-001591 UCLA IRB Approval Date: 10/9/2017 through 10/8/2018 Committee: Medical IRB 3
We invite you to participate in a study to understand how a change in dietary fat influences the brain-gut perception of hunger, food satisfaction and weight loss.
You must be:
During this study, your participation will last up to 14 weeks (including screen) and will include the following:
Compensation: Earn up to $275 and get a digital image of your brain. Study activity is free of charge and parking will be compensated.
This study is conducted by Arpana Gupta, PhD, G. Oppenheimer Center for Neurobiology of Stress and Resilience, in collaboration with Emeran A. Mayer, MD and in collaboration with Zhaoping Li, MD, PhD, UCLA Center for Human Nutrition.
If interested, please call Kimberly at 310-825-7217 or kimberlygonzalez@mednet.ucla.edu and refer to the "avocado diet related brain-gut interactions in obesity study."
Protocol ID:IRB#16-000187 UCLA IRB Approved Approval Date: 3/20/2018 Through: 10/10/2018 Committee: Medical IRB 3
We invite you to participate in a study to understand how the gut influences the brains' perception of hunger and changes in food satisfaction.
You must be:
Participation involves:
This study is conducted by Arpana Gupta, PhD, G. Oppenheimer Center for Neurobiology of Stress and Resilience, in collaboration with Emeran A. Mayer, MD.
If interested, please call Kimberly at 310-825-7217 or kimberlygonzalez@mednet.ucla.edu and refer to the "brain-gut interactions in obesity study."
Protocol ID: IRB #16-000187 UCLA IRB Approval Date: 10/11/2017 through: 10/10/2018 Committee: Medical IRB 3
Do you feel that your food cravings are taking over your New Year's resolution of eating healthier? If so, you can participate in a study to test the ability of a new therapy to control your food cravings.
To be eligible you must be:
Eligible participants will complete 11 visits over a period of four months where they will:
This study is conducted by Claudia Sanmiguel, MD, UCLA Ingestive Behavior and Obesity Program.
If you have questions or would like to participate, please contact Jean Stains, RN at 310-206-1758 or jstains@mednet.ucla.edu IRB # 15-001929, Approved date: 2/23/18 through 2/21/19 Committee: Medical IRB 3
We know the struggles of chronic disease can be difficult and can affect one's work productivity. Through this study, we ask for your help in understanding how coping with inflammatory bowel disease affects the daily lives of both the patient and his/her caregiver(s) in and how we can help improve life for both. The UCLA IBD patient-caregiver study will educate doctors, nurses, and the health care team to understand both the patient's and their caregivers' point of view in order to accommodate and to assure future quality care. Participants and their caregivers will be asked to do a 5-10-minute survey. A simple link via email will be sent to any willing participants to do at their convenience. Or, we would be happy to meet with the patients during their clinic visit.
If you have questions or would like to participate, please call Miriam Dvorsky or Dr. Aria Zand at 310-206-3778 or email them at mdvorsky@mednet.ucla.edu and azand@mednet.ucla.edu
IRB #15-00130
Are you interested in a non-invasive, non-drug therapy for mood symptoms? The purpose of this study is to learn more about anxiety and/or depression and is conducted by Dr. Kirsten Tillisch at the G. Oppenheimer Center for Neurobiology of Stress and Resilience.
If interested, please call 310-206-8545.
Protocol ID:IRB#15-001639 UCLA IRB Approved Approval Date: 10/12/2017 through 10/11/2018 Committee: Medical IRB 3
Cholangioscopy is an endoscopic technique used for direct visualization of the bile ducts. The new FDA approved digital Spyglass system introduced a digital sensor for better image quality, which will allow for better visualization and diagnosis. If you are a male or female >18 years old referred for the evaluation of biliary strictures (narrowing) or removal of difficult stones, you might be eligible to participate in the study. You must be undergoing ERCP along with DS Spyglass cholangioscopy as part of your clinical care at UCLA. The study will evaluate the clinical safety, feasibility and efficacy of the new Spyglass DS Spyglass cholangioscopy system for diagnostic imaging of biliary tract disorders (particularly those with biliary strictures and stones).
Inclusion/Exclusion Criteria:
This study is conducted by Dr. V. Raman Muthusamy. The study is coordinated by Amanda Moralde.
If interested, please call 310-267-3636.
Protocol ID: IRB# 16-000341 Approval Date: 3/16/2016 through 2/21/2019 Committee: Medical IRB 1
