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UCLA Vatche & Tamar Manoukian Division of Digestive Diseases

UCLA Vatche & Tamar Manoukian Division of Digestive Diseases

UCLA Vatche & Tamar Manoukian Division of Digestive Diseases
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UCLA Vatche & Tamar Manoukian Division of Digestive Diseases

Clinical Programs

Clinical Programs

Clinical Programs

  • Celiac Disease Program
  • Center for Inflammatory Bowel Diseases
  • Center for Obesity and METabolic Health (COMET)
  • UCLA Robert G. Kardashian Center for Esophageal Health
  • Familial Mediterranean Fever
  • Fecal Microbial Transplant
  • Functional GI Disorders Including IBS
  • General Gastroenterology
  • Hepatology
  • Integrative Digestive Health and Wellness Program
  • Interventional Endoscopy
  • Motility Program
  • Nutrition Program
  • Pancreaticobiliary Diseases
  • Celiac Disease Program
  • Center for Inflammatory Bowel Diseases
  • Center for Obesity and METabolic Health (COMET)
  • UCLA Robert G. Kardashian Center for Esophageal Health
  • Familial Mediterranean Fever
  • Fecal Microbial Transplant
  • Functional GI Disorders Including IBS
  • General Gastroenterology
  • Hepatology
  • Integrative Digestive Health and Wellness Program
  • Interventional Endoscopy
  • Motility Program
  • Nutrition Program
  • Pancreaticobiliary Diseases
  1. Home
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  3. Fecal Microbial Transplant

Fecal Microbial Transplant

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The divisions of infectious diseases and digestive diseases offer fecal microbial transplantation (FMT) for patients with refractory Clostridium difficile infections.

Recurrent Clostridium difficile infection has become a major challenge for patients and clinicians. Recurrence of infection after conventional treatment with standard antibiotics is common. FMT is an alternative treatment for recurrent C. difficile infection. Fecal microbial transplantation involves infusing processed stool from a healthy, pre-screened donor into the GI tract of a patient with C. difficile infection, typically by colonoscopy.  Recently published studies, including one in the New England Journal of Medicine (NEJM), indicate that this procedure is extremely effective for treating recurrent C. difficile infection. The NEJM study was a randomized controlled trial comparing FMT to conventional antibiotic therapy. The study was halted early after interim analysis demonstrated that FMT was significantly more effective than vancomycin.

To be eligible, patients must have documented C. difficle infection that has nto responded to two courses of appropriate conventional therapy. Patients who are pregnant, have toxic megacolon, or a medical condition that places the patient at unacceptably high risk for the procedure are ineligible. 

To make an appointment, please call 310-206-7663.

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Program Directors 

Eric Esrailian, MD, MPH
Eric Esrailian, MD, MPH
Chief, Vatche and Tamar Manoukian Division of Digestive Diseases
Director, Melvin and Bren Simon Digestive Diseases Center
Lincy Foundation Chair in Clinical Gastroenterology
Clinical Professor of Medicine
Daniel Z. Uslan, MD, FIDSA
Daniel Z. Uslan, MD, FIDSA
Director, Antimicrobial Stewardship Program
Associate Director, Clinical Epidemiology & Infection Prevention
Associate Clinical Professor of Medicine
Division of Infectious Diseases

IRB #13-001103

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