Studies show that more than 90 percent of bariatric patients lose 50 percent or more of their excessive body weight and are able to maintain a long-term weight loss of 50 percent excess body weight or more. (1) Of even greater significance, many bariatric surgery patients experience improvements in co-occurring disorders, such as the resolution of sleep apnea or improvements in hypercholesterolemia and hypertension. Some types of bariatric surgery also lead to improvements or the remission of type 2 diabetes mellitus which, prior to bariatric surgery, was thought to be a progressive and incurable disease requiring lifelong medication and lifestyle modification.

Endoscopic suturing to jumpstart weight loss

In recent years, however, published research has demonstrated that sustained weight loss can be difficult for some bariatric surgery patients, including even those who experience initial success. Most patients reach their maximum weight loss one to three years following surgery, and research shows that, on average, patients regain about 30 percent of their weight-loss after 10 years. About one-quarter of patients regain all of their lost weight by 10 years. Moreover, about 20 percent of patients who undergo bariatric surgery fail to lose significant weight - defined as less than 50 percent of excess body weight loss.

Weight regain is likely to be linked to a number of factors including:

• Over time, the pouch can expand, allowing the individual to eat more food without feeling as full and starting an insidious process of weight gain.
• The stoma can also stretch.
• A fistula can form in the connection between the pouch and rest of stomach. This is an abnormal pathway that is created with when the smaller stomach pouch grows and reconnects to the bypassed stomach. It occurs in 1 to 2 percent of patients.
• The patient's diet and exercise habits change. For example, consumption of high-calorie drinks is often the cause of gradual weight gain.

Many bypass patients who regain weight are mystified, frustrated and plagued by feelings of failure. Bariatric surgeons rarely recommend a second bypass surgery due to the increased risks associated with a repeat surgery. Primary care doctors may feel they have run out of solutions to help these patients.

Endoscopic suturing for bariatric revision provides an additional option to help these patients jump start the weight-loss process. The procedure involves insertion of an endoscope through the mouth (under monitored anesthesia) and assessing the stomach and intestines. If the pouch and/or stoma has been stretched, sutures can be placed to reduce the pouch size and opening. The result is a retightened structure that prompts renewed feelings of satiety to curb food intake.

Key points regarding endoscopic suturing for bariatric revision

• Suitable for people who have regained weight or failed to lose significant weight following gastric bypass surgery
• Addresses enlargement of the pouch and stoma
• Requires overnight fast prior to surgery but no bowel preparation
• Typically a one-hour outpatient procedure; may require an overnight stay to treat pain or nausea
• Minimal risks, such as those associated with any endoscopic surgery
• Proven efficacy
• Requires highly restricted diet for one month following surgery along with continued lifestyle modification (diet and exercise)

After the procedure

To optimize the chance of successful weight loss, prospective patients receive a consultation with a dietitian prior to surgery as well as follow-up counseling after the procedure. The patient is re-educated about the type of diet that should be followed post-surgery to avoid complications, facilitate weight loss and maintain long-term weight loss.

A follow-up appointment with the surgeon is scheduled for one month after the procedure.

Results

Endoscopic suturing for bariatric revision has been studied for more than a decade. A study published in 2013 in the journal Gastroenterology on patients who had weight regain after RYGB compared 50 patients who had endoscopic suturing for bariatric revision (also called transoral outlet reduction, or TORe) with patients who had a sham procedure. Patients who received endoscopic suturing experienced a 3.5 percent weight loss compared to 0.4% among the patients who underwent a sham procedure. (2). No significant procedure related complications occurred.

Frequently asked questions

• How much weight will I lose?
  • About 20 to 50 lbs. depending on an individual anatomy and motivation to succeed.
  • Can I continue to take medications after surgery?
    Patients should avoid taking pills for the first week following surgery and opt for liquid medication where possible. Discuss your options for medication with your primary care physician and specialists prior to surgery.
  • Will I need to follow a specific diet following surgery?
    Yes. Patients should adhere to a restricted diet, similar to the diet followed after the original RYGB surgery, for one month followed by a long-term diet that allows for the maintenance of weight loss.
  • When can I return to work?
    Most patients can return to work after one day.
  • Can you have this if you've had a different type of bariatric surgery, such as gastric banding?
    No. This procedure is for RYGB patients who have regained weight due to stretching of the stomach pouch and/or stoma.

Health insurance coverage / cash pricing

• Will my health insurance cover this procedure?
  
  • We can try to submit the procedure for insurance approval, as some insurances do provide coverage for the ESG. However, many still do not. UCLA will provide an estimate of out-of-pocket costs for the procedure, appointments with the endoscopists, and nutrition team visits.
• UCLA Health offers cash pricing for selected services including endoscopic treatments for weight loss. Follow the instructions below to view:
  • Go to https://www.uclahealth.org/patients-families/billing-insurance/price-transparency/cash-pricing
  • Click on the "figure of man" in the yellow circle that is named "Digestive System"
  • On the drop down menu, named "Choose Procedure or Surgery" select Endoscopic Gastric Sleeve or Gastric Bypass Revision according to procedure you are seeking

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References

1) F1000 Reports/Medicine. ncbi.nlm.nih.gov/pmc/articles/PMC3470459/
2) Gastroenterology. ncbi.nlm.nih.gov/pubmed/23567348