S. Thomas Carmichael, MD, PhD
UCLA Neurology Department Chair
S. Thomas Carmichael is a neurologist and neuroscientist in the Departments of Neurology and of Neurobiology at the David Geffen School of Medicine at UCLA. Dr. Carmichael is Professor Chair of the Department of Neurology, co-Director of the UCLA Broad Stem Cell Center and co-Director of the Regenerative Medicine Theme in the David Geffen School of Medicine. He has active laboratory and clinical interests in stroke and neurorehabilitation and how the brain repairs from injury. He received his MD and PhD degrees from Washington University School of Medicine in 1993 and 1994, and completed a Neurology residency at Washington University School of Medicine, serving as Chief Resident. Dr. Carmichael was a Howard Hughes Medical Institute postdoctoral fellow at UCLA from 1998-2001. He has been on the UCLA faculty since 2001. Dr. Carmichael’s laboratory studies the molecular and cellular mechanisms of neural repair after stroke and other forms of brain injury. This research focuses on the processes of axonal sprouting and neural stem cell and progenitor responses after stroke, and on neural stem cell transplantation. Dr. Carmichael is an attending physician on the Neurorehabilitation and Stroke clinical services at UCLA.
Dr. Carmichael has published important papers on stroke recovery that have defined mechanisms of plasticity and repair. These include the fact that the stroke produces stunned circuits that limit recovery, but can be restored to normal functioning with newly applied experimental drugs. His work has identified a novel brain “growth program” that is activated by stroke and leads to the formation of new connections. These studies have also identified how this growth program changes with age, and how specific molecules in the aged brain block the formation of new connections and of recovery. This and other work has led to new directions in stroke therapeutics, including therapies with stem cell and tissue engineering applications. Dr. Carmichael is in the midst of stroke stem cell development applications with the FDA and with biotechnology companies.
Dr. Flippen received his Bachelor of Arts degree in Psychology from Northwestern University in Evanston, Illinois and then obtained his medical degree from the University of Michigan School of Medicine. He subsequently completed his neurology Residency at the University of Maryland Medical System. After residency, he completed a Fellowship in Headache Medicine and Facial Pain at the Henry Ford Health System in Detroit, MI.
In 1997, Dr. Flippen joined the faculty of the Indiana University School of Medicine where he started their first Headache Clinic. Dr. Flippen has been on faculty at UCLA since 1999 and has served as Clerkship Director for the third year medical school course in Neurology and is a staff neurologist at Olive View-UCLA Medical Center. Dr. Flippen has a long history of active leadership in neurology education, including service on the American Academy of Neurology Education committee and as an oral examiner for the American Board of Psychiatry and Neurology. His teaching skill has been recognized with receipt of the UCLA Department of Neurology "Golden Hammer", an A.B. Baker Section Teacher Recognition Award from the AAN and the 2011 Mayo Clinic Distinguished Visiting Professor in Neurologic Education. He currently serves on the Neurology Residency Review committee of the ACGME, as the Secretary-Treasurer of the American Academy of Neurology Institute and on the AAN Board of Directors.
Dr. Flippen has expertise in management of refractory headache. His research interests are in the development of novel preventive therapies for migraine. His clinical interests include management of refractory headache, women's issues in headache and refractory facial pain.
Phone: 310-825-6681 | Fax: 310-206-4733