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Cancer,
Science & Research
UCLA Cancer Researcher Receives Award for Outstanding Achievement in Cancer Research
Dr. Roger Lo has received the 33rd Annual American Association of Cancer Research (AACR) Award for Outstanding Achievement in Cancer Research.
May 24, 2013
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3 min read
Cancer,
Science & Research
Method makes it easier to separate useful stem cells from 'problem' ones for therapies
Pluripotent stem cells can turn, or differentiate, into any cell type in the body, such as nerve, muscle or bone, but inevitably some of these stem cells fail to differentiate and end up mixed in with their newly differentiated daughter cells.
April 22, 2013
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4 min read
Cancer,
Science & Research
Breast cancer drug receives 'breakthrough therapy' designation from FDA
An experimental drug being investigated for the treatment of advanced breast cancer by researchers from the Revlon/UCLA Women's Cancer Research Program at UCLA's Jonsson Comprehensive Cancer Center this week received "breakthrough therapy" designation from the U.S.
April 12, 2013
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4 min read
Science & Research
Research suggests popular diabetes drugs can cause abnormal pancreatic growth in humans
Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida.
March 26, 2013
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5 min read
Cancer,
Science & Research
Combination therapy with experimental drug improves outlook for breast cancer patients
A combination therapy using an experimental new drug shows significant promise for women with a common type of breast cancer in which estrogen causes their tumors to grow, researchers with the Revlon/UCLA Women's Cancer Research Program at UCLA's Jonsson Comprehensive Cancer Center report.
December 5, 2012
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4 min read
Cancer,
Science & Research
Tumor Suppressor Genes Vital to Regulating Blood Precursor Cells in the Common Fruit Fly, UCLA Stem Cell Scientists Find
UCLA scientists have shown that two common tumor suppressor genes, TSC and PTEN, are vital to regulating the stem cell-like precursor cells that create the blood supply in Drosophila, the common fruit fly.
September 5, 2012
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3 min read
Cancer,
Science & Research
Glucose Deprivation Activates Feedback Loop that Kills Cancer Cells, UCLA Study Shows
UCLA researchers have focused on the "Warburg effect" as a possible target for cancer therapies have examined how biochemical signals present in cancer cells regulate the altered metabolic state.
July 11, 2012
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3 min read
Science & Research
Immune system molecule weaves cobweb-like nanonets to snag intestinal microbes
A multidisciplinary team of researchers has found that human alpha-defensin 6 (HD6) - a key component of the body's innate defense system - binds to microbial surfaces and forms "nanonets" that surround, entangle and disable microbes, preventing bacteria from attaching to or invading intestinal cells.
June 21, 2012
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7 min read
Cancer,
Science & Research
We Need to Talk: Researchers Report for the First Time How Cells Communicate to Activate Notch Signaling
During formation of multi-cellular organisms, cells need to talk to each other to make critical decisions as to what kind of cell to become, as well as when and where to become that cell type.
May 31, 2012
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4 min read
Cancer,
News about UCLA Health,
Science & Research
Group pools donations to boost research of rare pediatric diseases
New hope for deadly pediatric brain tumors; opening the door to improved diagnosis and treatment of epilepsy in children; and advanced genetic testing to better understand the causes of autism and cancer in kids.
May 30, 2012
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5 min read
Cancer,
Science & Research
Second Mutation in BRAF-mutated Melanoma not Contributing to Drug Resistance
A second mutation found in the tumors of patients with BRAF-mutated metastatic melanoma does not contribute to resistance to BRAF inhibitor drugs, a finding that runs counter to what scientists expected to be true.
April 5, 2012
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4 min read
Cancer,
Science & Research
Radiation generates cancer stem cells from less aggressive breast cancer cells
Breast cancer stem cells, thought to be the sole source of tumor recurrence, are known to be resistant to radiation therapy and don't respond well to chemotherapy.
February 15, 2012
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3 min read
Cancer,
Science & Research
UCLA researchers identify peptide that inhibits replication of hepatitis C virus
Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks the viral replication that can lead to liver cancer and cirrhosis.
February 2, 2012
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3 min read
Cancer,
Science & Research
Suppressing Protein Vital to Cell Division Stops Certain Cancer Cells from Proliferating, Kills Them Quickly
December 9, 2011
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4 min read
Cancer,
Science & Research
Renowned Cancer Researcher Dr. Owen Witte Named by President Obama to Serve on the President's Cancer Panel
Dr. Owen Witte was selected today by President Barack Obama to serve on the President’s Cancer Panel, which monitors the development and execution of the National Cancer Program.
November 29, 2011
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3 min read
Cancer,
News about UCLA Health,
Science & Research
UCLA Programs that Aid Poor Women, Fund Imaging Fellowships Receive Nearly $1 Million from the Avon Foundation for Women
A patient navigation program offered through UCLA’s Jonsson Comprehensive Cancer Center that helps poor, uninsured women and a program that funds the training of breast imaging fellows received nearly $1 million in grants raised during the ninth annual Avon Walk for Breast Cancer.
October 17, 2011
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4 min read
Cancer,
Science & Research
Two Scientists Receive Prestigious Grants from the National Institutes of Health
Two UCLA scientists have received prestigious awards from the National Institutes of Health (NIH) recognizing their leading-edge, innovative research.
September 28, 2011
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2 min read
Cancer,
Science & Research
Elderly Patients May be Undertreated for Prostate Cancer
It’s an ongoing debate: Should men over a certain age be treated for prostate cancer? And should these patients be submitted to treatments that may result in significant side effects if they may not live very much longer?
September 27, 2011
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4 min read
Cancer,
Science & Research
Scientists Create First Mapping of Molecule in Human Embryonic Stem Cells that may Regulate Genes
UCLA researchers have generated the first genome-wide mapping of a DNA modification called 5-hydroxymethylcytosine (5hmC) in human embryonic stem cells, and discovered that it is predominantly found in genes that are turned on, or active.
July 21, 2011
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3 min read
Cancer,
News about UCLA Health,
Science & Research
Agreement with Roche Gives Cancer Researchers Early Access to Leading-Edge Technologies
An agreement between UCLA and Roche will provide stem cell and cancer researchers with leading-edge technologies that will drive research capabilities and further the understanding of complex disease.
June 10, 2011
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2 min read