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Woman drawing a geometric shape
Cancer,
News about UCLA Health

UCLA Simms/Mann Center Director Receives Outstanding Clinical Care Award

Anne Coscarelli was awarded the Outstanding Clinical Care Award for 2013 by the American Psychosocial Oncology Society in February.
April 15, 2013   |  
4 min read
Image
Cancer,
Science & Research

Breast cancer drug receives 'breakthrough therapy' designation from FDA

An experimental drug being investigated for the treatment of advanced breast cancer by researchers from the Revlon/UCLA Women's Cancer Research Program at UCLA's Jonsson Comprehensive Cancer Center this week received "breakthrough therapy" designation from the U.S.
April 12, 2013   |  
4 min read
Pancreas illustration
Science & Research

Research suggests popular diabetes drugs can cause abnormal pancreatic growth in humans

Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida.
March 26, 2013   |  
5 min read
Breast Cancer Ribbon
Cancer,
Science & Research

Combination therapy with experimental drug improves outlook for breast cancer patients

A combination therapy using an experimental new drug shows significant promise for women with a common type of breast cancer in which estrogen causes their tumors to grow, researchers with the Revlon/UCLA Women's Cancer Research Program at UCLA's Jonsson Comprehensive Cancer Center report.
December 5, 2012   |  
4 min read
Julian A. Martinez-Agosto
Cancer,
Science & Research

Tumor Suppressor Genes Vital to Regulating Blood Precursor Cells in the Common Fruit Fly, UCLA Stem Cell Scientists Find

UCLA scientists have shown that two common tumor suppressor genes, TSC and PTEN, are vital to regulating the stem cell-like precursor cells that create the blood supply in Drosophila, the common fruit fly.
September 5, 2012   |  
3 min read
UCLA Jonsson Cancer Center Foundation Donor Wall
Cancer,
News about UCLA Health

Four Los Angeles Business and Community Leaders Join the Jonsson Cancer Center Foundation Board of Directors

Four Los Angeles business and community leaders joined the board of directors for the Jonsson Cancer Center Foundation, the fundraising arm of UCLA’s Jonsson Comprehensive Cancer Center.
July 18, 2012   |  
3 min read
Thomas Graeber
Cancer,
Science & Research

Glucose Deprivation Activates Feedback Loop that Kills Cancer Cells, UCLA Study Shows

UCLA researchers have focused on the "Warburg effect" as a possible target for cancer therapies have examined how biochemical signals present in cancer cells regulate the altered metabolic state.
July 11, 2012   |  
3 min read
Inflammatory Bowel Diseases
Science & Research

Immune system molecule weaves cobweb-like nanonets to snag intestinal microbes

A multidisciplinary team of researchers has found that human alpha-defensin 6 (HD6) - a key component of the body's innate defense system - binds to microbial surfaces and forms "nanonets" that surround, entangle and disable microbes, preventing bacteria from attaching to or invading intestinal cells.
June 21, 2012   |  
7 min read
Activate RAS protein attached to cancer cell
Cancer,
Science & Research

We Need to Talk: Researchers Report for the First Time How Cells Communicate to Activate Notch Signaling

During formation of multi-cellular organisms, cells need to talk to each other to make critical decisions as to what kind of cell to become, as well as when and where to become that cell type.
May 31, 2012   |  
4 min read
ped doctor and child
Cancer,
News about UCLA Health,
Science & Research

Group pools donations to boost research of rare pediatric diseases

New hope for deadly pediatric brain tumors; opening the door to improved diagnosis and treatment of epilepsy in children; and advanced genetic testing to better understand the causes of autism and cancer in kids.
May 30, 2012   |  
5 min read
UCLA melanoma researcher Dr. Roger Lo
Cancer,
Science & Research

Second Mutation in BRAF-mutated Melanoma not Contributing to Drug Resistance

A second mutation found in the tumors of patients with BRAF-mutated metastatic melanoma does not contribute to resistance to BRAF inhibitor drugs, a finding that runs counter to what scientists expected to be true.
April 5, 2012   |  
4 min read
Image
Cancer,
Science & Research

Radiation generates cancer stem cells from less aggressive breast cancer cells

Breast cancer stem cells, thought to be the sole source of tumor recurrence, are known to be resistant to radiation therapy and don't respond well to chemotherapy.
February 15, 2012   |  
3 min read
Liver Disease Microbiome
Cancer,
Science & Research

UCLA researchers identify peptide that inhibits replication of hepatitis C virus

Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks the viral replication that can lead to liver cancer and cirrhosis.
February 2, 2012   |  
3 min read
Owen Witte
Cancer,
Science & Research

Renowned Cancer Researcher Dr. Owen Witte Named by President Obama to Serve on the President's Cancer Panel

Dr. Owen Witte was selected today by President Barack Obama to serve on the President’s Cancer Panel, which monitors the development and execution of the National Cancer Program.
November 29, 2011   |  
3 min read
UCLA's Robert DuWors at Avon Cares or Life check presentation
Cancer,
News about UCLA Health,
Science & Research

UCLA Programs that Aid Poor Women, Fund Imaging Fellowships Receive Nearly $1 Million from the Avon Foundation for Women

A patient navigation program offered through UCLA’s Jonsson Comprehensive Cancer Center that helps poor, uninsured women and a program that funds the training of breast imaging fellows received nearly $1 million in grants raised during the ninth annual Avon Walk for Breast Cancer.
October 17, 2011   |  
4 min read
Hematopoietic stem cells and blood plasma joined together
Cancer,
Science & Research

Two Scientists Receive Prestigious Grants from the National Institutes of Health

Two UCLA scientists have received prestigious awards from the National Institutes of Health (NIH) recognizing their leading-edge, innovative research.
September 28, 2011   |  
2 min read
Image
Cancer,
Science & Research

Elderly Patients May be Undertreated for Prostate Cancer

It’s an ongoing debate: Should men over a certain age be treated for prostate cancer? And should these patients be submitted to treatments that may result in significant side effects if they may not live very much longer?
September 27, 2011   |  
4 min read
Steven Jacobsen
Cancer,
Science & Research

Scientists Create First Mapping of Molecule in Human Embryonic Stem Cells that may Regulate Genes

UCLA researchers have generated the first genome-wide mapping of a DNA modification called 5-hydroxymethylcytosine (5hmC) in human embryonic stem cells, and discovered that it is predominantly found in genes that are turned on, or active.
July 21, 2011   |  
3 min read
UCLA Jonsson Cancer Center Foundation Donor Wall
Cancer,
News about UCLA Health

Five Entertainment and Business Leaders Join Jonsson Cancer Center Foundation Board of Directors

Five executives from the entertainment, real estate and wine industries have joined the board of directors for the Jonsson Cancer Center Foundation.
July 7, 2011   |  
4 min read