PKD Research

What are Clinical Trials?

Learn More About Clinical Trials

Current Studies at UCLA

Tesevatinib

  • A Double-blind Randomized Parallel Group Study of the Efficacy and Safety of Tesevatinib in Subjects with Autosomal Dominant Polycystic Kidney Disease. The primary outcome measures are to change the height adjusted total kidney volume in ADPKD patient in two year time period. Click here for more information about Tesevatinib in Subjects with ADPKD
  • A Phase 1b/2a, Safety, Pharmacokinetic and Dose-Escalation Study of KD019 in Subjects with Autosomal Dominant Polycystic Kidney Disease. The primary outcome is to analysis a two year time period of change in glomerular filtration rate (GFR) in ADPKD patients. Click here for more information about Subjects with ADPKD

Tolvaptan

  • A Phase 3b, Multi-center, Open-label Trial to Evaluate the Long -Term Safety of Titrated Immediate-release Tolvaptan (OPC 41061, 30 mg to 120 mg/Day, Split Dose) in Subjects with Autosomal Dominant Polycystic Kidney Disease. The primary outcome is to determine the long-term safety of Tolvaptan in ADPKD patients. Click here for more information about Tolvaptan in Subjects with ADPKD

Completed Studies at UCLA

Tolvaptan

Overture

  • A Multi-center, Longitudinal, Observational Study of Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) to Establish the Rate, Characteristics, and Determinants of Disease Progression. Click here for more information about this study

If you are interested in participating in a PKD Trial, please contact (310) 825-7919 or email [email protected].

For all general questions and information, please contact (310) 954-2692 or email [email protected].