Pathology Outreach

Cytogenetics Laboratory

Contact Information

UCLA Pathology Outreach Client Services
Phone: 310-267-2680 | Email
Fax: 310-267-2685

  • New client account activation
  • Requisitions and supplies
  • Specimen requirements and transport
  • Report status and results
  • Arrange consult with pathologist assigned to case
  • Billing inquiries and assistance

Specimen delivery address:
UCLA Pathology Outreach
Specimen Receiving
10833 Le Conte Ave, A3-240 CHS
Los Angeles, CA 90095
Hours: Monday-Friday 6:00am-8:00pm

 

The UCLA Cytogenetics Laboratory is headed by ABMGG-certified Cytogeneticists and staffed by California-licensed Clinical Cytogenetics Scientists (CCS) and Hospital Laboratory Technicians (HLT). Our lab performs more than 8,000 cytogenetic assays annually for our in-patient population, community-based physicians and independently run pathology laboratories. This includes a high volume of hematological cases. State-of the art technologies are employed, including molecular cytogenetic techniques, such as fluorescence in situ hybridization (FISH) and chromosomal microarray analysis (CMA) for a wide range of clinical settings from cancer to prenatal and postnatal diagnosis.

Services

  • Oncology-Detection of cytogenetic molecular abnormalities in leukemias, lymphomas and solid tumors by standard and molecular cytogenetics, and molecular pathology.
  • Constitutional Prenatal and Postnatal-Diagnosis of microdeletion syndromes and numerical aberrations.

Forms

Oncology

  • Routine G-band chromosome analysis
  • Comprehensive FISH panels
  • SNP-Chromosomal Microarray Analysis (CMA)

Hematologic Malignancies

  • Acute Lymphocytic Leukemia (T-B ALL)
  • Acute Myelogenous Leukemia (AML)
  • Myelodysplastic Syndrome (MDS)
  • Myeloproliferative Neoplasms (MPN)
  • Chronic Myelogenous Leukemia (CML)
  • Non-Hodgkin's Lymphoma (NHL)
  • Plasma Cell Myeloma
  • Chronic Lymphocytic Leukemia (CLL)
  • Lymphoproliferative Disorder (LPD)

Solid Tumor

  • Uveal melanoma
  • Brain, CNS(Glioma, Neuroblastoma, Schwannoma/Rhabdoid)
  • Bladder
  • Breast
  • Soft tissue sarcoma (Ewing, alveolar rhabdomyosarcoma, myxoid/round cell liposarcoma, malignant liposarcoma/angiomatoid fibrous histiocytoma, well-differentiated liposarcoma)

Constitutional

Prenatal

  • Rapid fluorescence in situ hybridization (FISH) for aneuploidy screening.
    • Interphase analysis for trisomies of 13, 18 and 21, and aneuploidies of chromosomes X and Y, provides rapid detection of the most common chromosomal aneuploidies
  • Routine G-band chromosome analysis
    • Performed to obtain an overview of the fetal karyotype and chromosome structure in amniocytes, chorionic villi sampling and products of conception
  • SNP-Chromosomal Microarray Analysis (CMA) offers full genome coverage with nearly 2 million oligonucleotide markers

Postnatal

  • SNP-Chromosomal Microarray Analysis (CMA) offers full genome coverage with nearly 2 million oligonucleotide markers
  • Routine G-band chromosome analysis for couples with infertility or recurrent pregnancy loss

Faculty

Wayne W. Grody, MD, PhD
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Wayne W. Grody, MD, PhD

Molecular Genetic Pathology | Anatomic Pathology | Clinical and Laboratory Pathology

Founding Director, Molecular Diagnostics Laboratories and Clinical Genomics

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Alden Huang, PhD

Alden Huang, PhD

T. Niroshi Senaratne

T. Niroshi Senaratne, PhD

Associate Director, Cytogenetics Laboratory
Associate Director, Molecular Diagnostics Laboratories