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Cancer,
Science & Research
tar Wars Chemotherapy: Nanotechnology Pushes New Frontiers in Pediatric Cancer Research
May 11, 2010
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4 min read
Cancer,
Science & Research
Adult Survivors of Childhood Cancer Four Times More Likely to Develop Post-traumatic Stress Disorder
Young adult survivors of childhood cancers are four times more likely to develop Post-Traumatic Stress Disorder (PTSD) than their control group siblings, a Childhood Cancer Survivors Study has found.
May 3, 2010
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4 min read
Cancer,
Science & Research
Study Provides Proof in Humans of RNA Interference Using Targeted Nanoparticles
A team of researchers and clinicians from the UCLA Jonsson Comprehensive Cancer Center and the California Institute of Technology (Caltech) has published the first proof that a targeted nanoparticle can navigate into tumors.
March 25, 2010
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5 min read
Cancer,
Science & Research
Colon cancer treatment for older patients often less aggressive than recommended, study finds
New results from a major initiative on the quality of cancer care in the United States show that patients with a common type of colon cancer, especially older patients, often do not receive the aggressive treatment with chemotherapy that research shows is associated with better survival.
March 18, 2010
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6 min read
Cancer,
News about UCLA Health
Kenneth Jonsson, who helped found UCLA Health Jonsson Comprehensive Cancer Center, dead at 79
Kenneth A. Jonsson, who along with his late wife, Diana, helped to found UCLA Jonsson Comprehensive Cancer Center, died March 15 at his Pacific Palisades home.
March 16, 2010
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3 min read
Cancer,
Science & Research
Combination of Herceptin and Tykerb Effective Against Subset of Gastric Cancers
A combination of two targeted therapies already shown to be effective in breast cancer packs an effective one-two punch against a subset of gastric cancers that have a specific genetic mutation, a study at UCLA’s Jonsson Comprehensive Cancer Center has found.
March 4, 2010
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4 min read
Science & Research
Gene-based stem cell therapy specifically removes cell receptor that attracts HIV
UCLA AIDS Institute researchers successfully removed CCR5 — a cell receptor to which HIV-1 binds for infection but which the human body does not need from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.
February 25, 2010
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2 min read
Cancer,
Science & Research
Researchers Find Biomarkers in Saliva for Early Detection of Pancreatic Cancer
Physicians and scientists agree: If we cannot prevent cancer, the next best thing is to find it earlier to maximize the chances of a successful fight.
February 24, 2010
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3 min read
Cancer,
Science & Research
UCLA Researchers Perform Complete Genomic Sequencing of Brain Cancer Cell Line
UCLA researchers have performed the first complete genomic sequencing of a brain cancer cell line, a discovery that could facilitate personalized treatments based on the unique biological signature of an individual’s cancer.
January 29, 2010
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5 min read
Cancer,
Science & Research
Cancer Researcher Wins Prestigious Grant to Study Cancer Metabolism
Heather Christofk, a researcher with the UCLA Jonsson Comprehensive Cancer Center and the Institute for Molecular Medicine at UCLA, has received a prestigious grant to study how glucose metabolism is altered in cancer, a condition which leads to tumor growth.
January 20, 2010
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2 min read
Cancer,
Science & Research
Natural Compound Blocks Hepatitis C Infection
Researchers have identified two cellular proteins that are important factors in hepatitis C virus infection, a finding that may result in the approval of new and less toxic treatments for the disease, which can lead to liver cancer and cirrhosis.
January 6, 2010
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3 min read
Cancer,
Science & Research
Reactive Oxygen Levels in Fruit Flies Act as Cell Signaling Mechanism
For years, health conscious people have been taking antioxidants to reduce the levels of reactive oxygen in their blood and prevent the DNA damage done by free radicals, which are the result of oxidative stress. But could excessive use of antioxidants deplete our immune systems? Research at UCLA’s Jonsson Comprehensive Cancer Center has raised that question.
December 24, 2009
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4 min read
Cancer,
Science & Research
Enzyme Necessary for Healthy Immune System, Study Finds
Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response.
December 22, 2009
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4 min read
Cancer,
News about UCLA Health
UCLA, Caltech Launch Joint Center for Translational Medicine
UCLA and the California Institute of Technology (Caltech) have announced the establishment of the Joint Center for Translational Medicine, which will advance experimental research into clinical applications, including the diagnosis and treatment of diseases such as cancer.
December 17, 2009
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4 min read
Cancer,
Science & Research
Treating Deadly Brain Cancers by Targeting Their Metabolic Activity may Provide New Therapeutic Option
Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
December 14, 2009
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4 min read
Science & Research
UCLA researchers demonstrate that stem cells can be engineered to kill HIV
Researchers from the UCLA AIDS Institute and colleagues have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells — a process that potentially could be used against a range of chronic viral diseases.
December 7, 2009
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3 min read
Cancer,
Science & Research
Nanoparticles Found in Common Household Items Caused Genetic Damage in Mice
Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
November 19, 2009
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3 min read
Cancer,
News about UCLA Health
Cancer Researcher Receives Prestigious Scheele Award
Dr. Dennis Slamon, whose basic and clinical research led to the development of a new targeted therapy for breast cancer, has been awarded the prestigious Scheele Award in honor of his work.
November 11, 2009
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3 min read
Cancer,
Science & Research
FDA Approved Leukemia Drug Shows Promising Activity in Ovarian Cancer Cell Lines
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.
November 10, 2009
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3 min read
Cancer,
Science & Research
UCLA Researchers Receive $49.2 Million in Grants to Fund Research
Three UCLA scientists have been awarded grants totaling $49.2 million to take leading-edge stem cell science from the laboratory and translate it into new therapies for such devastating diseases as brain, ovarian and colorectal cancers, sickle cell and HIV/AIDS.
November 5, 2009
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10 min read