UCLA researchers presenting work at ASCO annual meeting

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Landon Hall
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LOS ANGELES – Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center, the David Geffen School of Medicine, and other UCLA institutions are presenting data and research findings at the American Society of Clinical Oncology’s annual meeting in Chicago June 3-7, 2022.   

Here are some of the abstracts and presentations scheduled, listed by session type, session title, and first author from UCLA:

 

EDUCATION SESSION

Predictors and Real-World Utilization of Prostate-Specific Radioligand Therapy: PSMA and Beyond

Jeremie Calais, MD, MSc, “Predictive Models for PSMA-Based Radioligand Therapy in Prostate Cancer.” Info.

 

ORAL ABSTRACT SESSIONS

Breast cancer

Richard S. Finn, MD, “Overall survival (OS) with first-line palbociclib plus letrozole (PAL+LET) versus placebo plus letrozole (PBO+LET) in women with estrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer (ER+/HER2− ABC): Analyses from PALOMA-2.” Info.

 

Genitourinary Cancer – Kidney and Bladder

Karim Chamie, MD, Department of Urology. “Final clinical results of pivotal trial of IL-15RαFc superagonist N-803 with BCG in BCG-unresponsive CIS and papillary nonmuscle-invasive bladder cancer (NMIBC).” Info.

 

Publication Only

Lung Cancer

Kathleen L. Ruchalski, MD, Department of Radiological Sciences. “Inter-reader reliability of immune-specific response criteria (irRECIST & iRECIST).” Info.

 

Health Services Research Quality and Improvement

Maria Garcia-Jimenez, MD, MHS, “Medical oncologists' perspectives of end-of-life care communication with racial/ethnic minority and limited English proficiency patients.” Info.

 

Symptoms and Survivorship

Tina Qing Huang, “Change in breast cancer risk perception related to perceived COVID-19 risk: A WISDOM sub-population analysis.” Info.

 

Head and Neck Cancer

Mykola Onyshchenko, MD, PhD, Harbor-UCLA Medical Center. “Clinical utility of circulating tumor DNA in patients with head and neck cancers.” Info.

 

POSTER SESSION

Prostate Cancer

Andrei Gafita, MD, “Novel framework for treatment response evaluation using PSMA-PET/CT in patients with metastatic castration-resistant prostate cancer (RECIP): An international multicenter study.” Info.

 

Health Services Research and Quality Improvement

Maria A. Velez, MD, “Cost of consent document (CD) translation is a potential barrier to consenting limited English-proficient participants (LEPPs) in non-industry–sponsored studies (NISS).” Info.

 

Lung Cancer

Velez, “Circulating tumor DNA (ctDNA) mutations associate with response in patients (pts) with extensive-stage small cell lung cancer (ES-SCLC) treated with talazoparib (TALA) and temozolomide (TMZ).” Info.

 

Gastrointestinal Cancer—Gastroesophageal, Pancreatic and Hepatobiliary

Zev A. Wainberg, MD, “Trial in progress: Phase 1b/3 study of bemarituzumab + mFOLFOX6 + nivolumab versus mFOLFOX6 + nivolumab in previously untreated advanced gastric and gastroesophageal junction (GEJ) cancer with FGFR2b overexpression (FORTITUDE-102).” Info.

 

Sarcoma

Noah C. Federman, MD, “A phase 1 dose-escalation/expansion clinical trial of mocetinostat in combination with vinorelbine in adolescents and young adults with refractory and/or recurrent rhabdomyosarcoma: Interim results.” Info.

 

Genitourinary Cancer—Prostate, Testicular and Penile

Loic Djaileb, MD, PhD, UCLA Ahmanson Translational Theranostics Division. “Predictive value of extra-prostatic disease detection by pre-operative PSMA-PET for biochemical recurrence-free survival in patients treated with radical prostatectomy: Follow-up analysis of a multicenter prospective phase 3 imaging trial.” Info.

 

Lung Cancer—Non-Small Cell Metastatic

Aaron E. Lisberg, MD, Department of Medicine. “Immunogenicity and disease control induced by a multineoantigen vaccine (ADXS-503) in patients with metastatic non–small cell lung cancer who have progressed on pembrolizumab.” Info.

Lisberg, “Phase I trial of in situ vaccination with autologous CCL21-modified dendritic cells (CCL21-DC) combined with pembrolizumab for advanced NSCLC.” Info.

Edward B. Garon, MD, MS, “EVOKE-02: A phase 2 study of sacituzumab govitecan (SG) plus pembrolizumab (pembro) with or without platinum chemotherapy in first-line metastatic non–small cell lung cancer (NSCLC).” Info.

 

Lung Cancer—Non-Small Cell Local-Regional/Small Cell/Other Thoracic Cancers

Jay M. Lee, MD, “Neoadjuvant and adjuvant capmatinib in resectable non–small cell lung cancer with MET exon 14 skipping mutation or high MET amplification: GEOMETRY-N trial.” Info.

 

Developmental Therapeutics—Immunotherapy

Sarah M. Larson, MD, “CD19/CD20 bispecific chimeric antigen receptor (CAR) in naïve/memory T cells for the treatment of relapsed or refractory non-Hodgkin lymphoma.” Info.

Lee S. Rosen, MD, “UCLA Division of Hematology-Oncology, FORTITUDE: Results of a phase 1a study of the novel transgene-armed and tumor-selective vector NG-350A with and without pembrolizumab (pembro).” Info.

Daniel S. Shin, MD, PhD, “Enhanced tumor control with a combination of APG-157 and immune checkpoint inhibitors for head and neck cancer.” Info.

 

Breast Cancer—Local/Regional/Adjuvant

Sara A. Hurvitz, MD, Department of Medicine, Division of Hematology/Oncology. “TRIO-US B-12 TALENT: Phase II neoadjuvant trial evaluating trastuzumab deruxtecan with or without anastrozole for HER2-low, HR+ early-stage breast cancer.”

 

Symptoms and Survivorship

John A. Glaspy, MD, MPH, “Open-label, phase 2 study of roxadustat for treatment of anemia in patients receiving chemotherapy for non-myeloid malignancies.” Info.

 

Central Nervous System Tumors

Vicki Liu, “Characterizing malignant transformation in patients with IDH-mutant glioma.” Info.

Timothy Francis Cloughesy, “GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma.” Info.

Ethan Wetzel, “A single-institution, retrospective examination of new contrast enhancement, progression, and pseudoprogression in IDH mutant glioma.” Info.

 

Prevention, Risk Reduction and Hereditary Cancer

Arya Aliabadi, “Increase in postmenopausal women with distant stage breast cancer in the United States over the last 18 years: Who is the most at risk?” Info.

 

Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes and Allotransplant

Sara Sakowitz, “Association of frailty with clinical and financial outcomes of allogeneic hematopoietic stem cell transplant.” Info.

 

Gastrointestinal Cancer—Colorectal and Anal

J. Randolph Hecht, MD, “Phase 2/3, randomized, open-label study of an individualized neoantigen vaccine (self-amplifying mRNA and adenoviral vectors) plus immune checkpoint blockade as maintenance for patients with newly diagnosed metastatic colorectal cancer (GRANITE).” Info.