2022 Symposium in Genomic Medicine: Frontiers in Gene Editing
Event Information
The David Geffen School of Medicine and UCLA Institute for Precision Health hosted the first Annual Ginsburg Symposium in Genomic Medicine: Frontiers in Gene Editing on May 11, 2022 at UCLA's Carnesale Commons. This full-day symposium highlighted progress and challenges in the therapeutic applications of gene-editing technology and associated ethical and regulatory issues.
The symposium included a keynote speaker, panel discussion, posters and oral presentations. Students, postdocs, faculty, and staff from all campuses were invited to attend.
All graduate students and postdoctoral fellows were encouraged to submit an abstract for the poster session.
Agenda
| Time | Topic |
|---|---|
| 8:00am – 8:30am | BREAKFAST |
| 8:30am - 8:40am | WELCOME REMARKS Steven M Dubinett, MD Dr. Allen and Charlotte Ginsburg |
| 8:45am - 9:20am | Hematopoietic Stem Cell Gene Therapy-Add it or Edit? Donald Kohn, MD Distinguished Professor of Microbiology, Immunology and Molecular Genetics UCLA |
| 9:25am - 10:00am | Engineering Next-Generation CAR-T Cells for Cancer Immunotherapy Yvonne Chen, MD, PhD Associate Professor of Microbiology, Immunology, and Molecular Genetics UCLA |
| 10:00am - 10:15am | BREAK |
| 10:15am - 11:00am | PLENARY SPEAKER Base Editing and Prime Editing: Precision Gene Correction Without Double-Strand DNA Breaks David Liu, PhD Professor and Director of the Merkin Institute of Transformative Technologies in Healthcare Broad Institute |
| 11:00am - 12:00pm | KEYNOTE SPEAKER CRISPR Cures: Genome Editing as a New Biomedical Frontier Jennifer Doudna, PhD Li Ka Shing Chancellor's Chair in Biomedical and Health Sciences Professor, Depts. of Molecular & Cell Biology and Chemistry UC Berkeley |
| 12:00pm - 12:15pm | ANNOUNCEMENT: 2022 GINSBURG FELLOW Dr. Dan Geschwind, MD, PhD and Dr. Allen Ginsburg, MD |
| 12:15pm – 1:00pm | LUNCH |
| 1:00pm - 1:30pm | LIGHTNING ROUND: Trainee Presentations (3) |
| 1:35pm - 2:10pm | Fetal Therapy for Single-Gene Disorders Tippi C. Mackenzie, MD Professor and Director of the Eli and Edythe Broad Institute for Regenerative Medicine UCSF |
| 2:15pm - 2:50pm | Ethics and Governance of Human Genome Editing R. Alta Charo, JD Professor Emerita of Law & Bioethics University of Wisconsin – Madison |
| 2:50pm - 3:00pm | BREAK |
| 3:00pm - 3:20pm | Disrupting Duchenne: Advancing Precision Genetic Medicine through Science, Policy, and Practice Diane Berry, PhD Senior Vice President, Global Policy, Government & Patient Affairs Sarepta Therapeutics |
| 3:20pm - 3:40pm | Development of Treatments for Rare Diseases Emil D. Kakkis, MD, PhD Chief Executive Officer, President and Director Ultragenyx |
| 3:40pm - 4:00pm | FDA’s Efforts to Advance Gene Therapy Peter Marks, MD, PhD Director, Center for Biologics Evaluation and Research U.S. Food and Drug Administration |
| 4:00pm - 4:10pm | BREAK |
| 4:10pm - 4:50pm | Meet the Experts: Frontiers in Ethical and Regulatory Perspectives Panelists: R. Alta Charo, JD, Diane Berry, PhD, Emil D. Kakkis, MD, PhD, Peter Marks, MD, PhD Moderator: Carrie Miceli, PhD, Professor of Microbiology Immunology and Molecular Genetics, UCLA |
| 4:50pm - 5:00pm | CLOSING REMARKS |
| 5:00pm - 6:30pm | WINE RECEPTION |