Alireza Sedarat, MD

Gastroenterology| Interventional Gastroenterology
Average rating: 4.9
(54 ratings)  
Accepting new patients
Primary Location
Santa Monica Digestive Diseases
1223 16th Street
Suite 3100
Santa Monica, California 90404


Dr. Sedarat joined UCLA in 2013 as a member of the interventional endoscopy within the Vatche and Tamar Manoukian Division of Digestive Diseases. His clinical interests encompass the development and application of advanced endoscopic techniques and interventions to diagnose, stage, treat and palliate a range of benign and malignant gastrointestinal disorders. He is proficient in the application of advanced endoscopic techniques including therapeutic ERCP, EUS with fine needle aspiration and biopsy, ERCP in surgically altered anatomy, interventional EUS (such as biliary drainage or rendezvous procedures, pancreas pseudocyst drainage, pancreas necrosectomy, fiducial placement and abscess drainage), pancreatic and biliary endotherapy, endoluminal stenting, endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), complex polypectomy, tumor ablation, deep (device assisted) enteroscopy, endoscopic fistula and leak closure, complex stricture dilation and endotherapy, endoscopic treatment of Barrett’s esophagus with mucosal resection and radiofrequency ablation, endoscopic antireflux procedures, Zenkers’ diverticulum myotomy, endoscopic management of surgical complications, and chromoendoscopy. Dr. Sedarat also performs bariatric endoscopy, including primary endoscopic therapies for obesity, endoscopic treatment of weight regain following bariatric surgery, and treatment of post-surgical complications.

He started the program at UCLA to offer the POEM procedure (peroral endoscopic myotomy) as treatment option for patients with achalasia and spastic disorders of the esophagus.  His research interests include endoscopic device development and application as well as evaluation of existing and emerging endoscopic technologies with a focus on improving patient outcomes. He is interested in the application of the emerging fields of submucosal and transluminal endoscopy, including endoscopic submucosal dissection (ESD) for early tumor resection, POEM, and application of devices and techniques to treat gastrointestinal disorders that traditionally were managed surgically. 

Dr. Sedarat completed his residency in internal medicine at the University of Pennsylvania. He completed his fellowship in gastroenterology here at UCLA and returned to UPenn to complete an advanced endoscopy fellowship. He is board certified in gastroenterology and is a member of the American Society of Gastrointestinal Endoscopy.





Advanced Interventional Endoscopy, Hospital of the University of Pennsylvania, 2013
Gastroenterology, UCLA School of Medicine, 2012


Internal Medicine, Hospital of the University of Pennsylvania, 2008


Internal Medicine, Hospital of the University of Pennsylvania, 2006


MD, UMDNJ New Jersey Medical School, 2005


  • Super Doctors® Southern California Rising Stars - 2021, 2020, 2019, 2018

Hospital Affiliations

Ronald Reagan UCLA Medical Center

UCLA Santa Monica Medical Center

Areas of Focus

Endoscopic submucosal dissection (esd)
Obesity and weight loss therapy
Peroral endoscopic myotomy
Endoscopic ultrasound
Endoscopic mucosal resection
Endoscopic endoluminal fundoplication


Meet Alireza Sedarat, MD
Achalasia: What you need to know
Endoscopic management of the peripancreatic fluid collections
Diagnosis and Management of Achalasia | Alireza Sedarat, MD & Jane Yanagawa, MD | UCLA
ESD & novel advanced endoscopic resection techniques
Haiku for the pylorus (G-POEM)
Endoscopy video forum
Pancreaticobiliary disease: The management of hilar cholangiocarcinoma
Pancreaticobiliary disease: ERCP
Diagnosing and Managing Pancreatic Adenocarcinoma | UCLA Digestive Diseases
Managing Complications of Acute and Chronic Pancreatitis | UCLA Digestive Diseases
Endoscopic therapy of foregut disorders
Recurrent acute pancreatitis
Chronic pancreatitis



  • Pancreaticobiliary disorders
  • GI malignancy
  • GI bleeding
  • Endoscopic device development and application
  • Emerging fields of endoscopic submucosal dissection (ESD) for early tumor resection and peroral endoscopic mytotomy (POEM) for achalasia palliation
  • GI malignancy
  • GI bleeding
  • Pancreaticobiliary disorders


  • Super Doctors® Southern California Rising Stars - 2021, 2020, 2019, 2018