Paul C. Boutros, PhD, MBA

Paul C. Boutros, PhD, MBA
Paul Boutros, PhD, MBA, is Director of Cancer Data Science for the UCLA Health Jonsson Comprehensive Cancer Center, Associate Director of Cancer Informatics at the Institute for Precision Health, Professor of Human Genetics and a secondary appointment in Urology, as well as an integral member of the Institute of Urologic Oncology and the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA. Dr. Boutros earned his B.Sc. degree from the University of Waterloo in Chemistry in 2004, and his Ph.D. degree from the University of Toronto, Canada, in Medical Biophysics in 2008. At Toronto, he also earned an executive M.B.A. from the Rothman School of Management. In 2008, Boutros started his independent research career at the Ontario Institute for Cancer Research first as a fellow (2008–2010) and then as principal investigator (2010–2018). He moved to California to join the UCLA faculty in 2018.


Raag Agrawal

Raag Agrawal 
MD/PhD Student 

Raag is an MD-PhD student at the UCLA-Caltech Medical Scientist Training Program. He received his BA in Biology from Columbia University where he researched transcription factor binding. His primary research focus is in leveraging large multi-omic datasets to improve Prostate cancer outcomes. 


Jaron Arbet Boutros Lab

Jaron Arbet, PhD
Bioinformatician 
Dr. Arbet completed his PhD in Biostatistics at the University of Minnesota.  Prior to joining the Boutros Lab in 2022, Jaron worked as a biostatistician in the medical device industry, and the University of Colorado Department of Biostatistics & Informatics, where he helped researchers design studies and analyze data for manuscript publications. Jaron's research interests include cancer genomics, multi-omics data integration, machine learning, predictive modeling, and feature selection.


Sarah Al-Hiyari, PhD

Sarah Al-Hiyari, PhD
Program Manager
Dr. Al-Hiyari completed her Ph.D. at the University of California, Los Angeles in 2017 and she is currently pursuing an MBA degree at UCLA Anderson.  Her previous research interests included understanding the genetic underpinnings of periodontal disease.


Caroline Y. Chen, MD

Caroline Y. Chen, MD
Hematology Oncology Fellow
Dr. Chen completed her medical degree at the University of Miami Miller School of Medicine, her internal medicine residency at UCLA, and is currently a hematology/oncology fellow at UCLA. She is interested in how informatics can be utilized to improve clinical decision making, treatment options, and ultimately patient outcomes.


Rachel Dang Boutros Lab

Rachel Dang
Staff Research Associate
Rachel joined the Boutros Lab after graduating from UCLA in 2022 where she majored in Computational and Systems Biology.


Faizal Eeman Boutros Lab

Faizal Eeman
Bioinformatician 
Faizal graduated with a BTech in Biotechnology from BSAR Crescent Institute of Science and Technology, India. During this program he interned at healthcare industries, MedGenome Labs and Twin Health where he developed interest toward health data science. Prior to joining the Boutros Lab in 2022, he worked as a Sr. Bioinformatics Analyst at MedGenome Labs – India, where he developed expertise in human NGS data analysis with focus on CNV/SV calling and variant prioritization. Faizal is presently driving the development of SV and CNA pipelines in the Boutros Lab for germline and somatic analyses.


Sorel Fitz Gibbon Boutros Lab

Sorel Tanya Fitz-Gibbon, PhD
Bioinformatician 
Sorel has been at UCLA since 1989, earning her B.Sc. degree in Molecular, Cellular and Developmental Biology in 1992, and her Ph.D. degree in Microbiology and Molecular Genetics in 1998.  Since then, she has worked as a bioinformatician in fields as diverse as extremophile microbial genomes, whole genome tree of life phylogenies, environmental metagenomes, human microbiomes, algal genetics and oak tree ecological genomics.  As an aside, from 2005-2009 she taught the UCLA Earth and Space Science's ‘Dinosaurs and their relatives' class.  She joined the Boutros lab in the UCLA Health Jonsson Comprehensive Cancer Center in 2022.


Tsumugi Gebo Bioinformatician

Tsumugi Gebo
Bioinformatician
Tsumugi graduated from UCSC and worked at a biotech start-up in the Bay Area before coming to UCLA. She is currently a bioinformatician working as part of Dr. Paul Boutros's lab in the UCLA Health Jonsson Comprehensive Cancer Center.  


 Alfredo Enrique Gonzalez, BS PhD Student

Alfredo Enrique Gonzalez, BS
PhD Student
Alfredo Enrique is a doctoral student and part of the UCLA Graduate Programs in Bioscience. Originally from Central America, he immigrated to the U.S. and received his undergraduate degree from Providence College. Following research stints at Harvard and the Broad Institute, in 2020 he joined the laboratory of Paul Boutros as a PhD student. His research interests primarily focus on the development of personalized therapies for cancer, sarcoma, childhood associated cancers, and predictive modeling of patient outcomes.


Roni Haas, PhD

Roni Haas, PhD
Postdoctoral Fellow
Roni completed her Ph.D. in the field of yeast quantitative genetics at the Technion - Israel Institute of Technology. Her doctoral studies were followed by short postdoctoral research at the Technion, centered around RNA bioinformatics, and particularly Adenosine to Inosine RNA editing and its role in regulating RNA abundance. Currently, Roni is a postdoctoral scholar in the Boutros laboratory. Her primary research interest is the germline activity of cancer hallmark pathways and its relation to tumor evolution and lethality.


Jee Yun Han, MS

Jee Yun Han, MS
PhD Student
Jee Yun is a graduate student in the Gene Regulation, Epigenomics and Transcriptomics (GREaT) home area of Molecular Biology Interdepartmental Program (MBIDP) at UCLA. She received B.S. and M.S. in the Department of Biotechnology at Korea University. During M.S. student, she studied on small non-coding RNA. After her M.S., she focused on Cancer Biology and Epigenomics at Seoul National University and UCSD, respectively, as a research associate. Her research interest is now "Gene regulation in Cancer".


 Aaron Kenneth Holmes Software Engineer

Aaron Kenneth Holmes
Software Engineer
Aaron has worked as a software engineer for 15 years in the private sector in industries as varied as philanthropy, network security, enterprise education, and entertainment. Most recently he worked as a Principal Engineer leading internal organizations in cloud migrations. Aaron is thrilled and excited to learn and be a part of cancer research and doing good for humanity. Outside of a self-driven passion for software and computing, his hobbies and interests include electrical engineering, gardening, the outdoors, motorcycles, helicopter piloting, ice skating, science fiction, video games, dogs, and so much more. Aaron was born and raised in southern California, and has lived as far north as Michigan where he took a liking to freezing weather. 


Rupert Hugh-White, PhD

Rupert Hugh-White, PhD
Bioinformatician
Rupert studied his B.Sc. in Biological Sciences at the University of Brighton, UK, before completing an M.Sc. in Bioinformatics at the University of Glasgow. He then studied for a Ph.D. at King's College London with a focus on understanding alternative pre-mRNA splicing through analysis of RNA-sequencing datasets. Rupert's current work is concerned with profiling the molecular biology of prostate cancer. In particular, he is focused on understanding the flow of information between alternative splicing and other stages of the gene expression pathway, and how this is influenced by the mutations which drive prostate cancer.


Jae Heon Jeong

Jae Heon Jeong, PhD
Postdoctoral Scholar
Jae completed his Ph.D in Bioengineering, specializing in Biomedical Informatics, at Seoul National University, South Korea, after earning a Bachelor of Science in Biotechnology and Bioengineering from SungKyunKwan University. During his doctoral studies, he concentrated on developing novel computational algorithms and web portals designed to discover cancer biomarkers and drug candidates using large-scale biomedical datasets. Currently, Jae is a postdoctoral scholar in the Boutros laboratory.


Dan Knight Software Engineer

Dan Knight
Software Engineer  
Dan is a software engineer who completed an undergraduate degree in Electronic Production and Design from Berklee College of Music in 2016, and joined the Boutros Lab in 2021. His career interest is in applying computer science and data science to find new solutions to important problems.


Julie Livingstone

Julie Livingstone
Bioinformatician
Julie completed her B.Sc in Biology at Queen's University and her M.Sc in Bioinformatics at McGill University. Her research interests include cancer genomics, transcriptomics and proteomics. She was a part of the Canadian Prostate Cancer Genome Network (CPC-GENE) and helped discover recurrent structural variants in intermediate risk samples. Currently, she is focused on RNA-sequencing analysis, including RNA editing and methylation in prostate cancer.


Emma Longshore

Emma Kaitlyn Longshore, MS 
Program Manager 

Emma completed her undergraduate studies at the University of Colorado Boulder and her Master's in Biomedical Engineering with special focus in Bioinformatics at New York University. Her primary clinical and research focuses are oncology informatics and machine learning algorithms for smarter patient treatment and data accessibility. 


Beth Neilsen Boutros Lab

Beth Neilsen, MD, PhD
Radiation Oncology Resident
Dr. Beth Neilsen received her Bachelor's degree in computer science from the Jeffrey Raikes School of Computer Science and Management within the University of Nebraska-Lincoln. She completed her MD/PhD training at the University of Nebraska Medical Center. Her PhD research utilized bioinformatic approaches to evaluate and identify novel therapeutic targets in Ras-mutated cancers from a genome-wide siRNA screen, which was supported by an NIH/NCI F30 grant. Dr. Neilsen completed a year of preliminary training in Internal Medicine at the University of Nebraska Medical Center before starting her radiation oncology residency at the University of California, Los Angeles. She was selected to complete the ABR Holman Research Pathway and joined the Boutros laboratory as a postdoctoral scholar. Her research interests include cancer heterogeneity and cancer evolution particularly in response to radiation treatment.  


Jieun Oh

Jieun Oh
PhD Student
Jieun is a Bioinformatics Ph.D student at UCLA. She graduated from the University of Hong Kong with a major in Biochemistry and a minor in computer science. She is interested in researching cancer and improving precision medicine through bioinformatics.


Kiarod Pashminehazar

Kiarod Pashminehazar
Software Engineer
Kiarod Pashminehazar holds a B.S. in Computer Science from UCLA. He is dedicated to applying his expertise to the field of biology with the goal to develop practical computational solutions that address complex biological challenges.


Yash Patel, MSc

Yash Patel, MSc
Bioinformatician
Yash holds a B.Sc. in Biology and Computer Science from McGill University and a M.Sc. in Computer Science studying RNA structural characteristics important for determining interactions with RNA-binding proteins. He is currently working on developing pipelines for processing and analyzing NGS data.


Zhuyu Qiu, MSc

Zhuyu Qiu, MSc
Biostatistician
Zhuyu holds a B.Sc. in Biological Sciences from China Agricultural University and an M.Sc. of Biostatistics from Columbia University. Her current work focuses on a large-scale prostate cancer-specific proteomics project and will perform machine-learning analyses on the data.


Julie Ramirez Office Manager

Julie Ramirez
Office Manager
Julie graduated from UCLA with a degree in Sociology. She started her career in UCLA in 2012 and has held positions in Pediatrics, the Cardiac Arrhythmia Center, and Geffen Academy at UCLA. In 2016, Julie completed her Master's degree in Public Administration.


Joseph Salmingo

Joseph Salmingo
Software Engineer
Joseph completed his undergraduate degree in Aerospace Engineering at UC San Diego, and has worked in multiple disciplines of engineering in the automotive and aeronautical sectors in both California and Japan. He is excited to be a part of cancer research to bring positive changes to society. His career interest is in creating software to make everyone's lives easier.


Helen Shan

Helen Shan, MD
Clinical Fellow
Helen completed her medical degree at Harvard, her internal medicine residency at UCLA, and will be starting her hematology-oncology fellowship at UCLA in the fall of 2024. Her research interests include leveraging multi-modal data types to enable more efficient drug discovery and rigorous, transparent clinical validations of cutting-edge research and applications of AI in oncology.


Mao Tian, PhD

Mao Tian, PhD
Bioinformatician
Mao completed her B. Sc in biotechnology at the Sichuan University, China. She got her Ph.D. in medical biology at the University of Southern California, studying the molecular mechanism of an oncogenic virus, Kaposi's Sarcoma Herpesvirus. She holds a sprightly interest in translational science, specifically cancer biomarker and drug target discovery. Currently, Mao is a junior bioinformatician in the Boutros laboratory researching cancer genomics and proteomics. She is also focusing on developing tools and pipelines for the lab.


Brandon Tsai, BS

Brandon Tsai, BS
MD/PhD Student
Brandon is an MD/PhD student at the UCLA David Geffen School of Medicine. As an undergraduate student at UCLA, he studied bioinformatics and tumor immunology under the mentorship of Dr. Owen Witte.


Nicholas Wang, MHS

Nicholas Wang, MHS
PhD Student
Nicholas Wang is currently a graduate student in the bioinformatics IDP studying germline effects on cancer evolution. His background includes a biomedical engineering degree from the University of Toronto, a master's in health science from Johns Hopkins, and work as a bioinformatician at a clinical service laboratory. His primary research interests involve the development and application of broadly applicable cancer screening and diagnostic methods.


Nicholas Wiltsie

Nicholas Eric Wiltsie, MS 
Sr. Software Engineer 

Nicholas Eric Wiltsie has two degrees in Mechanical Engineering from MIT: a Bachelor of Science in 2010 and a Master of Science in 2012. Nick's most recent position was a Senior Interdisciplinary Systems Engineer at Amazon Robotics. As the Senior Interdisciplinary Systems Engineer, Nick developed systems requirements, concept of operations document, FMEA for Amazon warehouses' prototype automated item intake and storage system. Nick likes photography, tinkering with robots, board games and training his chihuahua-pit bull, Zero. 


Helena Winata

Helena Winata
PhD Student
Helena grew up in Indonesia before moving to Vancouver, Canada to study Biophysics at the University of British Columbia. Her primary research interest is in using omics to improve early diagnosis and patient care in cancer. She is also interested in expanding her skills in machine learning and data science. 


Selina Wu

Selina Wu
PhD Student
Selina is a Ph.D. student in the Medical Informatics program at UCLA interested in translational medicine. She received a BS in Biochemistry from Boston College and worked in Biomarker & Assay Development before coming to UCLASelina is a first-year Ph.D. student in the Medical Informatics program at UCLA interested in translational medicine. She received a BS in Biochemistry from Boston College and worked in Biomarker & Assay Development before coming to UCLA.


Takafumi Yamaguchi, MSc

Takafumi Yamaguchi, MSc
Bioinformatician
Taka studied genetics and molecular biology at the University of Manitoba, before beginning a Master of Science at the University of Toronto, where he learned systems biology, programming and next generation sequencing (NGS) data analysis under the supervision of Dr. Fritz Roth. Upon graduation in 2013, Taka started working with Dr. Paul Boutros. His current research focus is on NGS data analysis and the development of NGS analysis pipelines, including DNA read quality control, alignment and mutation calling.


Nicole Zeltser PhD Student

Nicole Zeltser
PhD Student
Nicole is currently a PhD. student in the Human Genetics department at UCLA. After receiving her B.S. in animal science at Cal Poly San Luis Obispo, she decided to pursue her interest in the application of computational solutions to biological problems. As a member of the Boutros lab she plans to study the genomic landscape of cancer.


Chenghao Zhu, PhD

Chenghao Zhu, PhD
Postdoctoral Scholar
Chenghao completed his PhD in nutritional biology in 2019, and worked as a postdoctoral scholar at UC Davis before joining the UCLA Health Jonsson Comprehensive Cancer Center in August, 2020.  He is currently interested in cancer proteogenomics.