Paul C. Boutros, PhD, MBA
Paul Boutros, PhD, MBA, is Director of Cancer Data Science for the UCLA Jonsson Comprehensive Cancer Center, Associate Director of Cancer Informatics at the Institute for Precision Health, Professor of Human Genetics and a secondary appointment in Urology, as well as an integral member of the Institute of Urologic Oncology and the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA. Dr. Boutros earned his B.Sc. degree from the University of Waterloo in Chemistry in 2004, and his Ph.D. degree from the University of Toronto, Canada, in Medical Biophysics in 2008. At Toronto, he also earned an executive M.B.A. from the Rothman School of Management. In 2008, Boutros started his independent research career at the Ontario Institute for Cancer Research first as a fellow (2008–2010) and then as principal investigator (2010–2018). He moved to California to join the UCLA faculty in 2018.
Sarah Al-Hiyari, PhD
Dr. Al-Hiyari completed her Ph.D. at the University of California, Los Angeles in 2017 and she is currently pursuing an MBA degree at UCLA Anderson. Her previous research interests included understanding the genetic underpinnings of periodontal disease.
Arpi Yvette Beshlikyan
Arpi joined the Boutros Lab in 2021 after graduating from UCLA, where she majored in Computer Science and Engineering and minored in Bioinformatics. During that time, she worked as an undergraduate research assistant in the Coller Lab at UCLA, where she examined cell quiescence through ATAC-seq analysis. She’s passionate about applying computer science in interdisciplinary ways to design and build technology that contributes to health research and helps make people’s lives easier.
Caroline Y. Chen, MD
Hematology Oncology Fellow
Dr. Chen completed her medical degree at the University of Miami Miller School of Medicine, her internal medicine residency at UCLA, and is currently a hematology/oncology fellow at UCLA. She is interested in how informatics can be utilized to improve clinical decision making, treatment options, and ultimately patient outcomes.
Jack moved to LA after graduating from Michigan State University. He is interested in Bioinformatics and is excited to discover all that the university and the city have to offer.
Stefan Eng, Master's in Mathematical Statistics
Stefan did his undergrad in computer science & mathematics at Cal State Northridge. He has worked in a variety of industries such as at Jet Propulsion Laboratory, at CRESST/UCLA, and an internship at Novartis. He has his master’s degree in mathematical statistics from Gothenburg University, Sweden. In his free time he enjoys running, rock climbing, hiking and camping.
Tsumugi graduated from UCSC and worked at a biotech start-up in the Bay Area before coming to UCLA. She is currently a bioinformatician working as part of Dr. Paul Boutros's lab in the Jonsson Comprehensive Cancer Center.
Jenna graduated from UC Davis in 2017 with a bachelor's degree in genetics and genomics and a minor in computer science. She is now a PhD student in the Molecular Biology Interdepartmental Doctoral Program at UCLA and is co-mentored by Dr. Andrew Goldstein. She is interested in understanding how metabolic vulnerabilities can be targeted to treat aggressive prostate cancers.
Alfredo Enrique Gonzalez, BS
Alfredo Enrique is a doctoral student and part of the UCLA Graduate Programs in Bioscience. Originally from Central America, he immigrated to the U.S. and received his undergraduate degree from Providence College. Following research stints at Harvard and the Broad Institute, in 2020 he joined the laboratory of Paul Boutros as a PhD student. His research interests primarily focus on the development of personalized therapies for cancer, sarcoma, childhood associated cancers, and predictive modeling of patient outcomes.
Technical Program Manager
Hollie is a technical project manager with 15 years of experience developing growing and launching start-up programs in technology first Universities. Her primary responsibilities are wide-ranging, including managing the teams velocity using the newest project management collaboration tools to create systems that improve cloud infrastructure, code quality and boost productivity.
Roni Haas, PhD
Roni completed her Ph.D. in the field of yeast quantitative genetics at the Technion - Israel Institute of Technology. Her doctoral studies were followed by short postdoctoral research at the Technion, centered around RNA bioinformatics, and particularly Adenosine to Inosine RNA editing and its role in regulating RNA abundance. Currently, Roni is a postdoctoral scholar in the Boutros laboratory. Her primary research interest is the germline activity of cancer hallmark pathways and its relation to tumor evolution and lethality.
Jee Yun Han, MS
Jee Yun is a graduate student in the Gene Regulation, Epigenomics and Transcriptomics (GREaT) home area of Molecular Biology Interdepartmental Program (MBIDP) at UCLA. She received B.S. and M.S. in the Department of Biotechnology at Korea University. During M.S. student, she studied on small non-coding RNA. After her M.S., she focused on Cancer Biology and Epigenomics at Seoul National University and UCSD, respectively, as a research associate. Her research interest is now "Gene regulation in Cancer".
Aaron Kenneth Holmes
Aaron has worked as a software engineer for 15 years in the private sector in industries as varied as philanthropy, network security, enterprise education, and entertainment. Most recently he worked as a Principal Engineer leading internal organizations in cloud migrations. Aaron is thrilled and excited to learn and be a part of cancer research and doing good for humanity. Outside of a self-driven passion for software and computing, his hobbies and interests include electrical engineering, gardening, the outdoors, motorcycles, helicopter piloting, ice skating, science fiction, video games, dogs, and so much more. Aaron was born and raised in southern California, and has lived as far north as Michigan where he took a liking to freezing weather.
Rupert Hugh-White, PhD
Rupert studied his B.Sc. in Biological Sciences at the University of Brighton, UK, before completing an M.Sc. in Bioinformatics at the University of Glasgow. He then studied for a Ph.D. at King's College London with a focus on understanding alternative pre-mRNA splicing through analysis of RNA-sequencing datasets. Rupert's current work is concerned with profiling the molecular biology of prostate cancer. In particular, he is focused on understanding the flow of information between alternative splicing and other stages of the gene expression pathway, and how this is influenced by the mutations which drive prostate cancer.
Dan is a software engineer who completed an undergraduate degree in Electronic Production and Design from Berklee College of Music in 2016, and joined the Boutros Lab in 2021. His career interest is in applying computer science and data science to find new solutions to important problems.
Lydia Y. Liu
Lydia is a Ph.D. student at the University of Toronto. Her primary research interest is tumour heterogeneity.
Jieun is a Bioinformatics Ph.D student at UCLA. She graduated from the University of Hong Kong with a major in Biochemistry and a minor in computer science. She is interested in researching cancer and improving precision medicine through bioinformatics.
Yash Patel, MSc
Yash holds a B.Sc. in Biology and Computer Science from McGill University and a M.Sc. in Computer Science studying RNA structural characteristics important for determining interactions with RNA-binding proteins. He is currently working on developing pipelines for processing and analyzing NGS data.
Zhuyu Qiu, MSc
Zhuyu holds a B.Sc. in Biological Sciences from China Agricultural University and an M.Sc. of Biostatistics from Columbia University. Her current work focuses on a large-scale prostate cancer-specific proteomics project and will perform machine-learning analyses on the data.
Julie graduated from UCLA with a degree in Sociology. She started her career in UCLA in 2012 and has held positions in Pediatrics, the Cardiac Arrhythmia Center, and Geffen Academy at UCLA. In 2016, Julie completed her Master’s degree in Public Administration.
Adriana is a Ph.D. candidate at the University of Toronto. She joined the lab after completing her BSc. and MSc. at the University of Toronto studying evolutionary biology and population genomics. She is currently interested in the impacts of early evolution on the mutational landscape of tumours.
Mao Tian, PhD
Mao completed her B. Sc in biotechnology at the Sichuan University, China. She got her Ph.D. in medical biology at the University of Southern California, studying the molecular mechanism of an oncogenic virus, Kaposi's Sarcoma Herpesvirus. She holds a sprightly interest in translational science, specifically cancer biomarker and drug target discovery. Currently, Mao is a junior bioinformatician in the Boutros laboratory researching cancer genomics and proteomics. She is also focusing on developing tools and pipelines for the lab.
Brandon Tsai, BS
Brandon is an MD/PhD student at the UCLA David Geffen School of Medicine. As an undergraduate student at UCLA, he studied bioinformatics and tumor immunology under the mentorship of Dr. Owen Witte.
Nicholas Wang, MHS
Nicholas Wang is currently a graduate student in the bioinformatics IDP studying germline effects on cancer evolution. His background includes a biomedical engineering degree from the University of Toronto, a master’s in health science from Johns Hopkins, and work as a bioinformatician at a clinical service laboratory. His primary research interests involve the development and application of broadly applicable cancer screening and diagnostic methods.
Helena grew up in Indonesia before moving to Vancouver, Canada to study Biophysics at the University of British Columbia. Her primary research interest is in using omics to improve early diagnosis and patient care in cancer. She is also interested in expanding her skills in machine learning and data science.
Selina is a Ph.D. student in the Medical Informatics program at UCLA interested in translational medicine. She received a BS in Biochemistry from Boston College and worked in Biomarker & Assay Development before coming to UCLASelina is a first-year Ph.D. student in the Medical Informatics program at UCLA interested in translational medicine. She received a BS in Biochemistry from Boston College and worked in Biomarker & Assay Development before coming to UCLA.
Takafumi Yamaguchi, MSc
Taka studied genetics and molecular biology at the University of Manitoba, before beginning a Master of Science at the University of Toronto, where he learned systems biology, programming and next generation sequencing (NGS) data analysis under the supervision of Dr. Fritz Roth. Upon graduation in 2013, Taka started working with Dr. Paul Boutros. His current research focus is on NGS data analysis and the development of NGS analysis pipelines, including DNA read quality control, alignment and mutation calling.
Nicole is currently a PhD. student in the Human Genetics department at UCLA. After receiving her B.S. in animal science at Cal Poly San Luis Obispo, she decided to pursue her interest in the application of computational solutions to biological problems. As a member of the Boutros lab she plans to study the genomic landscape of cancer.
Chenghao Zhu, PhD
Chenghao completed his PhD in nutritional biology in 2019, and worked as a postdoctoral scholar at UC Davis before joining the UCLA Jonsson Comprehensive Cancer Center in August, 2020. He is currently interested in cancer proteogenomics.