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Cancer,
Science & Research

Reactive Oxygen Levels in Fruit Flies Act as Cell Signaling Mechanism

For years, health conscious people have been taking antioxidants to reduce the levels of reactive oxygen in their blood and prevent the DNA damage done by free radicals, which are the result of oxidative stress. But could excessive use of antioxidants deplete our immune systems? Research at UCLA’s Jonsson Comprehensive Cancer Center has raised that question.
December 24, 2009   |  
4 min read
Caius Radu
Cancer,
Science & Research

Enzyme Necessary for Healthy Immune System, Study Finds

Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response.
December 22, 2009   |  
4 min read
Dr. Owen N. Witte
Cancer,
News about UCLA Health

UCLA, Caltech Launch Joint Center for Translational Medicine

UCLA and the California Institute of Technology (Caltech) have announced the establishment of the Joint Center for Translational Medicine, which will advance experimental research into clinical applications, including the diagnosis and treatment of diseases such as cancer.
December 17, 2009   |  
4 min read
World Parkinson’s Day 2023 marks the five-year anniversary of Laurie and Steven C. Gordon’s $25 million gift to UCLA, which established their Commitment to Cure Parkinson’s Disease at the David Geffen School of Medicine.
Cancer,
Science & Research

Treating Deadly Brain Cancers by Targeting Their Metabolic Activity may Provide New Therapeutic Option

Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
December 14, 2009   |  
4 min read
Robert Schiestl
Cancer,
Science & Research

Nanoparticles Found in Common Household Items Caused Genetic Damage in Mice

Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
November 19, 2009   |  
3 min read
Dennis Slamon
Cancer,
News about UCLA Health

Cancer Researcher Receives Prestigious Scheele Award

Dr. Dennis Slamon, whose basic and clinical research led to the development of a new targeted therapy for breast cancer, has been awarded the prestigious Scheele Award in honor of his work.
November 11, 2009   |  
3 min read
Gottfried E. Konecny, MD
Cancer,
Science & Research

FDA Approved Leukemia Drug Shows Promising Activity in Ovarian Cancer Cell Lines

The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.
November 10, 2009   |  
3 min read
Dr. Dennis Slamon
Cancer,
Science & Research

UCLA Researchers Receive $49.2 Million in Grants to Fund Research

Three UCLA scientists have been awarded grants totaling $49.2 million to take leading-edge stem cell science from the laboratory and translate it into new therapies for such devastating diseases as brain, ovarian and colorectal cancers, sickle cell and HIV/AIDS.
November 5, 2009   |  
10 min read
Microscopic regenerated bone
Cancer,
Science & Research

New hydrogels show promise in treating bone defects

Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration compared to hydrogels that are currently available.
October 1, 2009   |  
3 min read
Breast cancer survivors sitting together
Cancer,
News about UCLA Health,
Science & Research

Innovative University of California Collaboration Targets Breast Cancer

UCLA is taking part in an unprecedented statewide University of California collaboration to revolutionize care for breast cancer patients by designing and testing, system-wide, new approaches to research, technology and health care delivery.
September 29, 2009   |  
7 min read
Dr. Cloughesy
Cancer,
Science & Research

Avastin Dramatically Increases Response, Survival in Recurrent Brain Cancers

The targeted therapy Avastin, alone and in combination with the chemotherapy drug CPT-11, significantly increased response rates, progression-free survival times and survival rates in patients with a deadly form of brain cancer that had recurred.
September 3, 2009   |  
4 min read
Cancer,
Science & Research

Crystal ball for brain cancer?

UCLA scientists have devised a new way to image brain tumors and predict which ones are most likely to benefit from the drug Avastin — before the patient ever takes a single dose.
August 3, 2009   |  
4 min read
UCLA Jonsson Cancer Center Foundation Taste for a Cure logo
Cancer,
News about UCLA Health

Entertainment Industry Executives to Head Foundation Board

Entertainment industry executives Randall M. Katz and Jay Sures have been named chair and vice chair of the board of directors for the Jonsson Cancer Center Foundation (JCCF), the fundraising arm of UCLA’s Jonsson Comprehensive Cancer Center.
July 28, 2009   |  
3 min read
Woman drawing a geometric shape
Cancer,
Behavioral Health,
News about UCLA Health

New Center Providing Integrative Oncology Care Opens

A new center providing leading-edge integrated care to cancer patients and their families launched today at UCLA’s Jonsson Comprehensive Cancer Center, offering such services as art therapy and QiGong, one-on-one and group counseling and advice on nutritional, spiritual and complementary approaches to healing.
June 27, 2009   |  
6 min read
Lung cancer image
Cancer,
Science & Research

Researchers Develop Model that May Help Identify Lung Cancer Stem Cells

Researchers at UCLA’s Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.
June 16, 2009   |  
5 min read
Mark Litwin, MD 2020
Cancer,
Science & Research

Study Details Quality of Life for Prostate Cancer Patients Four Years Out From Treatment

A long-term study by researchers at UCLA’s Jonsson Comprehensive Cancer Center found that the three most common treatments for localized prostate cancer had significant impacts on patients’ quality of life, a finding that could help guide doctors and patients in making treatment decisions.
June 9, 2009   |  
4 min read
Robert Schiestl
Cancer,
Science & Research

Researchers for the First Time Link Intestinal Inflammation to Systemic Chromosome Damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.
June 2, 2009   |  
4 min read
Virtual clinical trials
Cancer,
News about UCLA Health,
Science & Research

Leading-Edge Research Management System Launched

In an effort to improve and streamline management of clinical trials, UCLA’s Jonsson Comprehensive Cancer Center has acquired and recently launched Velos eResearch software that allows for better use of information systems and clinical databases in medical research.
April 29, 2009   |  
4 min read
Fritz C. Eilber, MD
Cancer,
Science & Research

Using PET/CT Imaging, Researchers Can Tell in a Single Treatment if Chemotherapy is Working

Oncologists often have to wait months before they can determine whether a treatment is working.
April 15, 2009   |  
3 min read
Michael L. Steinberg, MD
Cancer,
News about UCLA Health,
Science & Research

UCLA Acquires Tool That Delivers Higher Doses of Radiation in Less Time

UCLA has added a new tool to its cancer-fighting arsenal, a state-of-the-art image-guided device that provides more accurate, concentrated doses of radiation, allowing patients to be treated in fewer visits and suffer from fewer side effects.
March 30, 2009   |  
5 min read