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Cancer,
Science & Research
Enzyme Necessary for Healthy Immune System, Study Finds
Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response.
December 22, 2009
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4 min read
Cancer,
Science & Research
Treating Deadly Brain Cancers by Targeting Their Metabolic Activity may Provide New Therapeutic Option
Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
December 14, 2009
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4 min read
Science & Research
UCLA researchers demonstrate that stem cells can be engineered to kill HIV
Researchers from the UCLA AIDS Institute and colleagues have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells — a process that potentially could be used against a range of chronic viral diseases.
December 7, 2009
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3 min read
Cancer,
Science & Research
Nanoparticles Found in Common Household Items Caused Genetic Damage in Mice
Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
November 19, 2009
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3 min read
Cancer,
Science & Research
FDA Approved Leukemia Drug Shows Promising Activity in Ovarian Cancer Cell Lines
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.
November 10, 2009
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3 min read
Cancer,
Science & Research
UCLA Researchers Receive $49.2 Million in Grants to Fund Research
Three UCLA scientists have been awarded grants totaling $49.2 million to take leading-edge stem cell science from the laboratory and translate it into new therapies for such devastating diseases as brain, ovarian and colorectal cancers, sickle cell and HIV/AIDS.
November 5, 2009
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10 min read
Cancer,
Science & Research
New hydrogels show promise in treating bone defects
Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration compared to hydrogels that are currently available.
October 1, 2009
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3 min read
Cancer,
News about UCLA Health,
Science & Research
Innovative University of California Collaboration Targets Breast Cancer
UCLA is taking part in an unprecedented statewide University of California collaboration to revolutionize care for breast cancer patients by designing and testing, system-wide, new approaches to research, technology and health care delivery.
September 29, 2009
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7 min read
Cancer,
Science & Research
Avastin Dramatically Increases Response, Survival in Recurrent Brain Cancers
The targeted therapy Avastin, alone and in combination with the chemotherapy drug CPT-11, significantly increased response rates, progression-free survival times and survival rates in patients with a deadly form of brain cancer that had recurred.
September 3, 2009
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4 min read
Cancer,
Science & Research
Crystal ball for brain cancer?
UCLA scientists have devised a new way to image brain tumors and predict which ones are most likely to benefit from the drug Avastin — before the patient ever takes a single dose.
August 3, 2009
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4 min read
Cancer,
Science & Research
Researchers Develop Model that May Help Identify Lung Cancer Stem Cells
Researchers at UCLA’s Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.
June 16, 2009
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5 min read
Cancer,
Science & Research
Study Details Quality of Life for Prostate Cancer Patients Four Years Out From Treatment
A long-term study by researchers at UCLA’s Jonsson Comprehensive Cancer Center found that the three most common treatments for localized prostate cancer had significant impacts on patients’ quality of life, a finding that could help guide doctors and patients in making treatment decisions.
June 9, 2009
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4 min read
Cancer,
Science & Research
Researchers for the First Time Link Intestinal Inflammation to Systemic Chromosome Damage
UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.
June 2, 2009
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4 min read
Cancer,
News about UCLA Health,
Science & Research
Leading-Edge Research Management System Launched
In an effort to improve and streamline management of clinical trials, UCLA’s Jonsson Comprehensive Cancer Center has acquired and recently launched Velos eResearch software that allows for better use of information systems and clinical databases in medical research.
April 29, 2009
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4 min read
Cancer,
Science & Research
Using PET/CT Imaging, Researchers Can Tell in a Single Treatment if Chemotherapy is Working
Oncologists often have to wait months before they can determine whether a treatment is working.
April 15, 2009
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3 min read
Cancer,
News about UCLA Health,
Science & Research
UCLA Acquires Tool That Delivers Higher Doses of Radiation in Less Time
UCLA has added a new tool to its cancer-fighting arsenal, a state-of-the-art image-guided device that provides more accurate, concentrated doses of radiation, allowing patients to be treated in fewer visits and suffer from fewer side effects.
March 30, 2009
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5 min read
Cancer,
News about UCLA Health,
Science & Research
UCLA Launches Urologic Oncology Institute to Develop Leading-Edge Therapies
UCLA has launched a first-of-its-kind, patient-centered institute dedicated to developing leading-edge therapies for the treatment of kidney, bladder, testicular and prostate cancers.
March 3, 2009
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4 min read
Cancer,
News about UCLA Health,
Science & Research
UCLA launches new Institute of Urologic Oncology
UCLA has launched a first-of-its-kind, patient-centered institute dedicated to developing leading-edge therapies for the treatment of kidney, bladder, testicular and prostate cancers.
March 3, 2009
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3 min read
Cancer,
Science & Research
Low-Income Men More Likely to be Diagnosed with Advanced Prostate Cancers
Low-income men are more likely to present with advanced prostate cancers, most likely because they don’t receive screening services shown to reduce the diagnosis of later-stage cancers, a UCLA study found.
December 16, 2008
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3 min read
Cancer,
Science & Research
Scientists Prove Endothelial Cells Give Rise to Blood Stem Cells During Embryonic Development
Stem cell researchers at UCLA have proven definitively that blood stem cells are made during mid-gestational embryonic development by endothelial cells, the cells that line the inside of blood vessels.
December 3, 2008
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4 min read