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Heart
Science & Research

UCLA-led team finds a stem-cell derived mechanism that could lead to regenerative therapies for heart damage

A UCLA-led team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, possibly leading to new therapies for heart disease and cardiac damage.
October 17, 2023   |  
3 min read
liquid biopsy grant
Cancer,
Science & Research

Cancer researchers awarded $4.6 million to advance liquid biopsy test for lung cancer

UCLA investigators received a $4.6 million grant from the National Cancer Institute to develop and improve liquid biopsy technologies for the early detection of lung cancer — the leading cause of cancer death in both men and women in the U.S.
October 13, 2023   |  
3 min read
Nanocapsule
Cancer,
Science & Research

Drug-filled nanocapsule helps make immunotherapy more effective in mice

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.
October 11, 2023   |  
3 min read
Cancer Cells
Cancer,
Science & Research

Scientists develop roadmap to create new treatment strategies for ovarian cancer

UCLA researchers have created a roadmap looking at different ways to use the immune system to fight ovarian cancer, which could ultimately lead to the development of more effective immunotherapeutic strategies to better treat the often-lethal cancer.
October 11, 2023   |  
3 min read
Ameya Champhekar
Cancer,
Science & Research

Scientists identify new pathway activated by interferon-gamma that leads to tumor cell death

Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new role for a protein called extracellular signal-regulated kinase (ERK) in a pathway activated by interferon-gamma that can trigger cells to self-destruct.
October 9, 2023   |  
3 min read
Scale
Science & Research

A UCLA-led team may have found the key to stimulating human brown adipose tissue into combating obesity

A UCLA-led team of researchers has found nerve pathways that supply brown adipose tissue (BAT), a type of tissue that releases chemical energy from fat metabolism as heat – a finding that could pave the way toward using it to treat obesity and related metabolic conditions.
October 4, 2023   |  
3 min read
Kyung Sung
Cancer,
Science & Research

Researchers awarded $2.8 million to develop AI models

A team of investigators was awarded $2.8 million from the National Cancer Institute to develop an artificial intelligence model capable of improving the identification of prostate cancer in Black men, addressing a critical health care disparity.
October 4, 2023   |  
2 min read
Tanya Stoyanova
Cancer,
Science & Research

Tanya Stoyanova receives Department of Defense award to find new lung cancer treatments

Dr. Tanya Stoyanova, associate professor of molecular and medical pharmacology and urology at the David Geffen School of Medicine at UCLA, was awarded a $350,000 Idea Development Award from the Department of Defense.
October 3, 2023   |  
2 min read
exercise and gut microbiome
Healthy Lifestyle,
Science & Research
Illustration of gut bacteria in intestines
Science & Research

Discrimination alters brain-gut ‘crosstalk,’ prompting poor food choices and increased health risks

People frequently exposed to racial or ethnic discrimination may be more susceptible to obesity and related health risks in part because of a stress response that changes biological processes and how we process food cues. These are findings from UCLA researchers conducting what is believed to be the first study directly examining effects of discrimination on responses to different types of food as influenced by the brain-gut-microbiome (BGM) system.
October 2, 2023   |  
5 min read
Myocites
News about UCLA Health,
Science & Research
Blood sugar monitor
Science & Research

Pharmacist-led intervention can improve medication adherence among Latinos with type 2 diabetes

UCLA-led research suggests that diabetes control can significantly improve for Latinos when a pharmacist implements an intervention that addresses these patients’ barriers to medication adherence.
September 28, 2023   |  
3 min read
Dr. Mina Sedrak
Cancer,
Science & Research

Dr. Mina Sedrak receives $3.4 million grant from National Institutes of Health

Dr. Mina Sedrak has received a five-year, $3.4 million grant from the NIH to examine how exercise and certain drugs may be able to slow chemotherapy-related accelerated aging seen in breast cancer survivors.
September 27, 2023   |  
2 min read
Edward Garon
Cancer,
Science & Research

Dr. Edward Garon receives $3.5 million from NIH to personalize immunotherapy based on individual patients’ mutations

Dr. Edward Garon was awarded two grants totaling over $3.5 million from the National Institutes of Health to help improve outcomes for patients with early and advanced stages of non-small cell lung cancer.
September 27, 2023   |  
2 min read
Microscopic image of neurons
Science & Research

Scientists regenerate neurons that restore walking in mice after paralysis from spinal cord injury

In a new study in mice, a team of researchers uncovered a crucial component for restoring functional activity after spinal cord injury, showing that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.
September 21, 2023   |  
4 min read
bone breaking
News about UCLA Health,
Science & Research
Man walking under overpass
Science & Research

Living in a disadvantaged neighborhood affects food choices, weight gain and the microstructure of the brain

Research from UCLA David Geffen School of Medicine shows living in a disadvantaged neighborhood can affect food choices, weight gain and even the microstructure of the brain.
September 15, 2023   |  
4 min read