Paul C. Boutros, PhD, MBA
Paul Boutros, PhD, MBA, is Director of Cancer Data Science for the UCLA Jonsson Comprehensive Cancer Center, Associate Director of Cancer Informatics at the Institute for Precision Health, Professor of Human Genetics and a secondary appointment in Urology, as well as an integral member of the Institute of Urologic Oncology and the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA. Dr. Boutros earned his B.Sc. degree from the University of Waterloo in Chemistry in 2004, and his Ph.D. degree from the University of Toronto, Canada, in Medical Biophysics in 2008. At Toronto, he also earned an executive M.B.A. from the Rothman School of Management. In 2008, Boutros started his independent research career at the Ontario Institute for Cancer Research first as a fellow (2008–2010) and then as principal investigator (2010–2018). He moved to California to join the UCLA faculty in 2018.
Sarah Al-Hiyari, PhD
Dr. Al-Hiyari completed her Ph.D. at the University of California, Los Angeles in 2017 and she is currently pursuing an MBA degree at UCLA Anderson. Her previous research interests included understanding the genetic underpinnings of periodontal disease.
Caden Bugh, BSc
Caden is currently working as a software engineer, and he has a BS in Computer Science from the University of Wisconsin - Madison.
Ardalan Davarifar, MD
Hematology Oncology Fellow
Dr. Davarifar completed his medical and doctoral degrees at the Albert Einstein College of Medicine and his internal medicine residency at Columbia University. His primary clinical and research interests include bone and soft tissue sarcomas.
Natalie is a PhD candidate in the department of Medical Biophysics at the University of Toronto. She completed her bachelor of computer science with a specialization in bioinformatics from the University of Waterloo. Her graduate research has explored biomarkers and cancer subtyping in prostate cancer and breast cancer.
Tsumugi graduated from UCSC and worked at a biotech start-up in the Bay Area before coming to UCLA. She is currently a bioinformatician working as part of Dr. Paul Boutros's lab in the Jonsson Comprehensive Cancer Center.
Jenna graduated from UC Davis in 2017 with a bachelor's degree in genetics and genomics and a minor in computer science. She is now a PhD student in the Molecular Biology Interdepartmental Doctoral Program at UCLA and is co-mentored by Dr. Andrew Goldstein. She is interested in understanding how metabolic vulnerabilities can be targeted to treat aggressive prostate cancers.
Alfredo Enrique Gonzalez, BS
Alfredo Enrique is a doctoral student and part of the UCLA Graduate Programs in Bioscience. Originally from Central America, he immigrated to the U.S. and received his undergraduate degree from Providence College. Following research stints at Harvard and the Broad Institute, in 2020 he joined the laboratory of Paul Boutros as a PhD student. His research interests primarily focus on the development of personalized therapies for cancer, sarcoma, childhood associated cancers, and predictive modeling of patient outcomes.
Jee Yun Han, MS
Jee Yun is a graduate student in the Gene Regulation, Epigenomics and Transcriptomics (GREaT) home area of Molecular Biology Interdepartmental Program (MBIDP) at UCLA. She received B.S. and M.S. in the Department of Biotechnology at Korea University. During M.S. student, she studied on small non-coding RNA. After her M.S., she focused on Cancer Biology and Epigenomics at Seoul National University and UCSD, respectively, as a research associate. Her research interest is now "Gene regulation in Cancer".
Aaron Kenneth Holmes
Aaron has worked as a software engineer for 15 years in the private sector in industries as varied as philanthropy, network security, enterprise education, and entertainment. Most recently he worked as a Principal Engineer leading internal organizations in cloud migrations. Aaron is thrilled and excited to learn and be a part of cancer research and doing good for humanity. Outside of a self-driven passion for software and computing, his hobbies and interests include electrical engineering, gardening, the outdoors, motorcycles, helicopter piloting, ice skating, science fiction, video games, dogs, and so much more. Aaron was born and raised in southern California, and has lived as far north as Michigan where he took a liking to freezing weather.
Katie is a Ph.D. candidate in the Department of Medical Biophysics at the University of Toronto and a post-graduate affiliate at the Vector Institute. She holds a B.Sc from McMaster University in Chemical Biology. Katie's research focuses on the interplay between germline and somatic variants in prostate cancer.
Rupert Hugh-White, PhD
Rupert studied his B.Sc. in Biological Sciences at the University of Brighton, UK, before completing an M.Sc. in Bioinformatics at the University of Glasgow. He then studied for a Ph.D. at King's College London with a focus on understanding alternative pre-mRNA splicing through analysis of RNA-sequencing datasets. Rupert's current work is concerned with profiling the molecular biology of prostate cancer. In particular, he is focused on understanding the flow of information between alternative splicing and other stages of the gene expression pathway, and how this is influenced by the mutations which drive prostate cancer.
Gina Kim, BSc
Gina is a software developer who completed her undergraduate degree at UCLA in 2018. She interned at IBM Watson and Amazon previously, and started working full-time at Amazon in Seattle after graduation. She decided she wanted to go back into a more biological focus in her career, and moved to LA to work as a software engineer at the Boutros Lab in late 2019. Her career related interests include usability, personalized medicine, and virtual reality. Outside of work, she enjoys making music and experimenting with recipes.
Connie is a Ph.D. candidate in the Department of Medical Biophysics at the University of Toronto. She completed her Bachelor of Mathematics with a specialization in Computational Mathematics at the University of Waterloo. She is currently working on a pan-cancer analysis of somatic molecular changes associated with sex, ancestry, and age.
Lydia Y. Liu
Lydia is a Ph.D. student at the University of Toronto. Her primary research interest is tumour heterogeneity.
Julia Livingstone, M.Sc
Julie completed her B.Sc in Biology at Queen’s University and her M.Sc in Bioinformatics at McGill University. Her research interests include cancer genomics, transcriptomics and proteomics. She was a part of the Canadian Prostate Cancer Genome Network (CPC-GENE) and helped discover recurrent structural variants in intermediate risk samples. Currently, she is focused on RNA-sequencing analysis, including RNA editing and methylation in prostate cancer.
Alexander Markowitz, PhD
Dr. Alex Markowitz received his bachelor degree at the University of Maryland in biological sciences. During his undergraduate career, he joined his first research laboratory and studied the physiology of the retina. This experience led him to pursue graduate education and training at the University of Southern California where he received a PhD in Neuroscience for his research on the underlying biophysical mechanisms of peripheral auditory neurons in their function to encode sound. Currently, Alex is a postdoctoral fellow in the Boutros laboratory studying cellular proliferation across cancer types at DNA, RNA, and protein levels. Completion of this research will provide insight into the underlying mechanisms of cellular proliferation and may provide insight into future therapies for cancer.
Neil Mendhiratta, MD
Neil completed his undergraduate degree at the University of Pennsylvania, where he majored in Biophysics with a special focus on computational neuroscience and neural modeling. He then went on to complete a combined MD/MS in clinical investigation at New York University. His research focused on refining techniques for the diagnosis and risk stratification of prostate cancer, specifically by exploring the clinical impact of multiparametric MRI imaging in disease detection and characterization. Neil is an avid soccer, golf, and volleyball player, and continues to enjoy these activities in his new home in Los Angeles.
Natsai Nyakudarika, MD
Gynecologic Oncology Fellow
Dr. Nyakudarika graduated from Princeton University with a B.A. in Molecular Biology. Thereafter, she spent two years in Shanghai, China teaching, before completing her Medical Degree at Northwestern University Feinberg School of Medicine. She did residency in Obstetrics and Gynecology at University of California, San Francisco. She is currently a Gynecologic Oncology Fellow at UCLA where her research interests are in bridging healthcare disparities as well as the use of molecular diagnostics to inform prognosis and treatment of gynecologic cancers.
Courtney A. Penn, MD
Gynecologic Oncology Fellow
Dr. Penn completed her medical degree at the Perelman School of Medicine at University of Pennsylvania, her obstetrics and gynecology residency at University of Michigan, and is currently a fellow in gynecologic oncology at Cedars-Sinai. She is currently working with Dr. Boutros on the molecular landscape of obesity-associated endometrial cancer.
Zhuyu Qiu, M.Sc.
Zhuyu holds a B.Sc. in Biological Sciences from China Agricultural University and an M.Sc. of Biostatistics from Columbia University. Her current work focuses on a large-scale prostate cancer-specific proteomics project and will perform machine-learning analyses on the data.
Julie graduated from UCLA with a degree in Sociology. She started her career in UCLA in 2012 and has held positions in Pediatrics, the Cardiac Arrhythmia Center, and Geffen Academy at UCLA. In 2016, Julie completed her Master’s degree in Public Administration.
Adriana is a Ph.D. candidate at the University of Toronto. She joined the lab after completing her BSc. and MSc. at the University of Toronto studying evolutionary biology and population genomics. She is currently interested in the impacts of early evolution on the mutational landscape of tumours.
Shu Tao, PhD
Dr. Tao completed his doctoral degree at Georgetown University Department of Biology, and worked as Staff Scientist at City of Hope Integrative Genomics Core before joining UCLA Jonsson Comprehensive Cancer Center in December 2019. His research interests primarily focus on building and implementing computational pipeline for germline and somatic variant detection.
Nicholas Wang, MHS
Nicholas Wang is currently a graduate student in the bioinformatics IDP studying germline effects on cancer evolution. His background includes a biomedical engineering degree from the University of Toronto, a master’s in health science from Johns Hopkins, and work as a bioinformatician at a clinical service laboratory. His primary research interests involve the development and application of broadly applicable cancer screening and diagnostic methods.
Takafumi Yamaguchi, M.Sc.
Taka studied genetics and molecular biology at the University of Manitoba, before beginning a Master of Science at the University of Toronto, where he learned systems biology, programming and next generation sequencing (NGS) data analysis under the supervision of Dr. Fritz Roth. Upon graduation in 2013, Taka started working with Dr. Paul Boutros. His current research focus is on NGS data analysis and the development of NGS analysis pipelines, including DNA read quality control, alignment and mutation calling.
Wenyan Zhao, M.Sc.
Wenyan have a B.Sc. in Bioinformatics from Tongji University and a M.Sc. in Biostatistics from UCLA. Her focus is on statistical analysis and inference in health-related field.