To see the most recent news about what's happening in the Biomechanics Lab at UCLA, you can take a look at the UCLA Orthopaedic Biomechanics Annual Newsletter.
Our research group consists of David McAllister, MD, Keith Markolf, PhD, Daniel Boguszewski, PhD, Frank Petrigliano, MD, and Kristofer Jones, MD.
Dr. McAllister is a Professor of Orthopaedic Surgery and chief of the sports medicine service at UCLA. He specializes in all areas of orthopaedic sports medicine and has special expertise in knee ligament injuries and knee ligament biomechanics. In addition to running a busy sports medicine clinic, he is actively involved in research and in the education and mentoring of medical students, residents, and fellows in both the basic science and clinical research arenas.
Dr. Markolf is a Professor of Orthopaedic Surgery with over 40 years of experience in biomechanics research. He invented and developed a special technique for directly measuring forces in both cruciate ligaments of the knee with custom designed load cells. This has brought prominence to UCLA, as we are the only lab in the world using this direct measurement technique.
Dr. Boguszewski is an Assistant Professor of Orthopaedic Surgery. His expertise is in using a robotic manipulator to study knee joint biomechanics to improve injury prevention and repair techniques. With a background in mechanical and biomedical engineering, his specialty is in developing methods and techniques to utilize the robot to applying physiologic loading conditions to the knee.
Dr. Petrigliano is an Assistant Professor of Orthopaedic Surgery, specializing in knee, shoulder, and elbow injury. Dr. Petrigliano is extensively involved in both clinical and laboratory research, with interests including cartilage repair and transplantation, arthroscopic shoulder repair (rotator cuff tears and labrum tears), arthroscopic shoulder stabilization, cruciate ligament reconstruction, and elbow ligament reconstruction.
Dr. Jones is an Assistant Professor of Orthopaedic Surgery, specializing in knee, shoulder and elbow injury. His specific interest is in joint preservation procedures, including modern cartilage restoration and transplantation techniques. Active in both clinical and laboratory research, his interests include the surgical treatment of shoulder and elbow injuries in the throwing athlete and articular cartilage restoration procedures in the knee.
Drs. McAllister and Markolf have had a longstanding collaboration with significant contributions and high quality publications in the field of orthopaedic research. Their vast experience and combination of expertise from both a clinical and basic science perspective has established the UCLA Orthopaedic Biomechanics Lab as a leader in orthopaedic research. Together they have worked to train and mentor Dr. Boguszewski to lead the lab into exciting new and innovative areas of research.
Dr. Boguszewski's expertise is in biomedical engineering and robotics. The use of a robotic testing system to study knee joint function allows combined motion and force control to measure corresponding kinematic instabilities under simulated physiologic conditions. Our innovative approach provides an opportunity for enhanced studies of the knee that have never before been performed, providing insight into physiologic function and mechanisms of knee injury.
The UCLA Orthopaedic Biomechanics Lab is focused on training future clinician scientists in the area of orthopaedic research. We have had sustained success in mentoring and training the next generation of researchers, from residents and medical students to undergraduate students and high school interns. It is a core belief in our lab that teaching passionate young investigators in orthopaedic research is fundamental to the future of our field. We have established a summer internship position with Marymount High School focused on promoting women in science. With this position, we hope to educate and inspire young women leaders in science and research. We also participate in the annual Bioengineering Capstone Design Project with a group of undergraduate senior biomedical engineers.
High School Interns
Katherine Moses, Marymount High School (2014)
Lindsey McAllister, Marymount High School Intern (2015)
Medical Students
Paul Yang, University of Miami Miller School of Medicine (2012-2013)
Nirav Joshi, University of Miami Miller School of Medicine (2013-2015)
Justin Mathew, David Geffen School of Medicine at UCLA (2015-2016)
Residents
Dean Wang, UCLA Orthopaedic Surgery (2013)
Edward Cheung, UCLA Orthopaedic Surgery (2014-2015)
Kent Yamaguchi, UCLA Orthopaedic Surgery (2015-2016)
Dr. Boguszewski was a New Investigator Recognition Award Finalist at the 2015 Orthopaedic Research Society Meeting.
Dr. Cheung received the 1st Place Poster Award at the 2015 Western Orthopaedic Association Meeting.
Boguszewski DV, Wang D, Joshi NB, Petrigliano FA, Markolf KL, McAllister DR. The Effect of Different Preconditioning Protocols on Anterior Knee Laxity After ACL Reconstruction with Four Commonly Used Grafts. J Bone Joint Surg Am. 2015 Jul 1;97(13):1059-66.
Boguszewski DV, Cheung EC, Joshi NB, Markolf KL, McAllister DR. Gender Differences in Knee Laxity and Stiffness: A Cadaveric Study. Am J Sports Med. 2015 Dec;43(12):2982-7.
Cheung EC, Joshi NB, Boguszewski DV, Wang D, McAllister DR. Anatomic Factors that May Predispose Female Athletes to ACL Injury. Curr Sports Med Rep. 2015 Sep-Oct;14(5):368-72.
Boguszewski DV, Joshi NB, Yang PR, Markolf KL, Petrigliano FA, McAllister DR. Location of the Natural Knee Axis for Internal-External Tibial Rotation. Knee. [Article in Press]
Ed Cheung, MD and Nirav Joshi, MD working in the lab.
Nirav Joshi, MD providing instruction to Katie Moses.
Ed Cheung, MD presenting at the annual local Longmire Scientific Day
Dan Boguszewski, PhD presenting at the annual national Orthopaedic Research Society Meeting.
Dan Boguszewski, PhD with Justin Mathew and Kent Yamaguchi at the UCLA Josiah Brown Poster Fair.
Lindsey McAllister operating the robot.
Internship Program on display on Sunset Blvd.
Pictured (left to right):
Ed Cheung, MD,
Paul Yang, MD (previous research fellow),
Dan Boguszewski, PhD,
Nirav Joshi, MD,
Keith Markolf, PhD,
David McAllister, MD,
Lindsey McAllister (future research intern)
