Obstetrics & Gynecology

Newsletter Winter 2021

Message from Department Chair, Deborah Krakow, MD

As we can finally view the unprecedented challenges of 2020 in our rearview mirror, we should look forward to 2021 with a sense of gratitude and hope.  First, gratitude.  Over most of 2020 our doctors, nurses and other health professionals worked in increasingly risky settings to deliver first class care and support to inpatients and outpatients.  COVID impacts everyone - and doesn’t recognize a family expecting a new child or seeking assistance in planning a family, or a woman battling cancer.  We continue to maintain a full schedule of services with very close attention to protecting our staff and patients from COVID-19 exposure.  This work has required so much creative resolve and courage amidst so much uncertainty, and requires us all to endure changing schedules, workflows, and loss of many meaningful personal interactions. It is so difficult not to hug a crying patient or the parents of a new baby.  COVID has forced us to sacrifice some of the elements of what makes us human, to ensure safety for all.  

Deborah Krakow
Deborah Krakow, MD, Chair, UCLA Obstetrics and Gynecology

Second, hope.  While we still have many tough days ahead, the start of 2021 brings us much hope for the future.  The education and training of our future health professionals has continued strong during this difficult time.  Vaccines whose efficacy seemed a dream last spring are now here and with them comes optimism that perhaps we might be turning a corner toward the pandemic’s end.  And most important our healthcare system continues to hold steady through what is arguably one of the biggest challenges we have ever faced.

Our UCLA faculty and staff has been keenly focused on maintaining availability of services for our patients during this challenging time.  In this issue of OBGYNews you will meet Dr. Christina Han, our new Division Director for Maternal-Fetal Medicine, and hear about recent successful efforts to streamline collaborations with experts across UCLA Health to improve care for women with complex pregnancies - from pre-conception to pregnancy to post-partum services.  You will also read about new groundbreaking research in the lab of Dr. Sandra Orsulic, studying mechanisms in the microenvironment that contribute to cancer initiation and progression, and using that information to identify markers for early cancer detection and generate models for testing targeted therapies.  And you’ll learn more about our newest OBGYN Fellowship in Minimally Invasive Gynecologic Surgery (MIGS), a two year fully accredited program that will begin in July with the 2021-2022 academic year.  

With gratitude and hope, I wish you all continued health and safety in 2021 and thank you for all that you do to support our patients and their families.  

Deborah Krakow, MD

Clinical Update 

Advances in Maternal-Fetal Medicine Care

Caring for pregnant individuals with complex medical, obstetrical or fetal diagnoses is a challenge for providers, but early identification and application of a multidisciplinary care model can optimize outcomes. 

Christina Han, MD, Associate Clinical Professor of Obstetrics and Gynecology and Division Director of Maternal-Fetal Medicine, is making it a priority for the high-risk obstetrics service to streamline collaborations with experts across the UCLA Health system to improve care for women with complex pregnancies, from pre-conception to pregnancy to the postpartum period.  Dr. Han joined the faculty of UCLA’s Department of Obstetrics and Gynecology in October, and is currently building multi-disciplinary programs for cardio-obstetrics, diabetes in pregnancy, preconception care, and advanced prenatal diagnosis and genetic screening. 

For those individuals with heart disease who desire pregnancy or are pregnant, UCLA relies on a collaborative approach to care with experts in maternal-fetal medicine, adult cardiology, pediatric cardiology, anesthesiology, neonatology, nursing, and mental health. These teams work together to provide specialized care in the most complicated scenarios, often with joint counseling sessions and multidisciplinary meetings. Yalda Afshar, MD, PhD, Assistant Professor and maternal-fetal medicine specialist in Obstetrics and Gynecology at UCLA, was recently an integral part of a large, multidisciplinary team of specialty providers coordinating care for a mother with pulmonary hypertension at 25-weeks gestation. UCLA’s top specialists from multiple departments came together to coordinate this extremely high-risk, but successful, undertaking to deliver a healthy baby in the intensive care unit. "When the family decided that they were going to continue with the pregnancy, we were ready," said Dr. Afshar. The story was featured on KABC-TV, and is just one example of the quality care provided by the UCLA high-risk obstetrics service.

Committed to being at the forefront of science, our maternal-fetal medicine specialists are also committed to advances in research and education.  At the helm, Deborah Krakow, MD, Chair of Obstetrics and Gynecology and Professor of Obstetrics and Gynecology, Orthopedics and Human Genetics at UCLA, currently holds a PO1 and R01 aimed at identifying genes and molecular basis for recessive chondrodysplasias and musculoskeletal disorders.  

Carla Janzen, MD, PhD, Associate Professor and Maternal-Fetal Medicine specialist in Obstetrics and Gynecology at UCLA, is part of a team of researchers spearheading a study to identify complications of pregnancy utilizing free-standing genetic material shed from the placenta into the mother’s blood. The team’s effort to advance knowledge about the placenta and maternal health will hopefully guide further development of tests to help diagnose pregnancy disorders earlier.

The Division of Maternal-Fetal Medicine is also actively involved in the University of California Fetal Consortium, a transdisciplinary collaboration among the five University of California medical centers aimed at optimizing maternal, fetal, and neonatal outcomes. Our experts and trainees in Maternal-Fetal Medicine and Pediatrics contribute to the Consortium by leading and participating in projects aimed at training, clinical research, and quality improvement initiatives. 

Another priority for Dr. Han is to build an enhanced portfolio of clinical trials to improve outcomes for women with complex pregnancies. UCLA Obstetrics and Gynecology is currently recruiting pregnant subjects for prospective clinical trials in COVID-19, mental health disorders, and thromboprophylaxis, with additional clinical trials in the pipeline. 

Coronavirus Outcomes in Mother-infant Pairs (COMP) is a prospective observational study evaluating clinical outcomes, viral shedding and development of immunity in mother-infant pairs affected by COVID-19. Rashmi Rao, MD, Health Sciences Clinical Assistant Professor, is co-principal investigator on this project. Dr. Rao is also leading the Heparin Dosing for Antepartum Hospitalizations (HEPDOSE) trial that aims to assess the effect standard dosing versus gestational age-based dosing of unfractionated heparin has on receipt of neuraxial anesthesia as well as to evaluate the pharmacokinetics and pharmacodynamics of unfractionated heparin in pregnancy.

PRIORITY (Pregnancy CoRonavirus Outcomes RegIsTrY) is a nationwide study of pregnant or recently pregnant women who are either under investigation for Coronavirus infection (COVID-19) or have been confirmed to have COVID-19 to help patients and doctors better understand how COVID-19 impacts pregnant women and their newborns. Dr. Afshar is a co-principal investigator on this study, along with a team of co-PIs from UCSF.

The New Moms Study, a prospective cohort study aiming to determine efficacy of standard versus technology-based mental health treatment during pregnancy, is led by Misty Richards, MD, MS, Assistant Clinical Professor of UCLA Obstetrics and Gynecology and UCLA Division of Child and Adolescent Psychiatry and Medical Director of Perinatal Psychiatry, and Dr. Rao, who is also the Obstetric Medical Director of Mental Health. This interdisciplinary team also heads the Maternal Outpatient Mental health Services (MOMS) Clinic serving the mental health needs of women during the perinatal period. 

Dr. Han’s vision is “to expand on the strong foundations of our division to build a world-class Maternal-Fetal Medicine program that delivers compassionate and evidence-based patient care, performs cutting-edge innovative research, and trains a strong cohort of future Maternal-Fetal Medicine leaders.”

Education: UCLA Obstetrics and Gynecology Fellowship Programs

The UCLA Department of Obstetrics and Gynecology is committed to providing a robust and rigorous training ground for future physician-scientists. Our integrated and multidisciplinary fellowship programs are structured to train academically oriented obstetrics and gynecologists, innovative scientists and world leaders in women's health. We have six of the 7 ACOG-recognized subspecialty fellowship programs including, Complex Family Planning, Female Pelvic Medicine and Reconstructive Surgery, Gynecologic Oncology, Reproductive Endocrinology and Infertility, Maternal-Fetal Medicine and Minimally Invasive Gynecologic Surgery, plus a unique fellowship in Patient-Centered Outcomes Research Training in Urologic and Gynecologic Cancers. Our fellowship programs are led by nationally recognized leaders in these disciplines, preparing our fellows for distinguished careers in clinical practice, education, research, and public policy and service.

The Minimally Invasive Gynecologic Surgery (MIGS) Fellowship, our newest program, provides a 2-year comprehensive training curriculum in advanced gynecologic endoscopy and minimally invasive gynecologic surgery.  Our program is fully accredited by the the American Association of Gynecologic Laparoscopists (AAGL), the leading association promoting minimally invasive gynecologic surgery among surgeons worldwide. The UCLA MIGS Fellowship is led by program director Tamara Grisales, M.D., Health Sciences Assistant Clinical Professor of Obstetrics and Gynecology, and associate program director Sukrant Mehta, M.D., Health Sciences Assistant Clinical Professor of Obstetrics and Gynecology. The fellowship will commence with the 2021-22 academic year. 

Meet Christina Han, MD, the Newly Named Division Director for Maternal-Fetal Medicine

Dr. Christina Han
Dr. Christina Han

UCLA OBGYN is pleased to announce the hiring of Christina Han, MD, Associate Clinical Professor of Obstetrics and Gynecology and Division Director of

 Maternal-Fetal Medicine. Dr. Han was most recently at the Center for Fetal Medicine and Women’s Ultrasound, a hybrid private-academic practice in Los Angeles. She received her medical degree from David Geffen School of Medicine at UCLA and fulfilled her residency in obstetrics and gynecology at Cedars-Sinai Medical Center. Dr. Han completed a maternal-fetal medicine fellowship at Yale University School of Medicine / Yale-New Haven Hospital, where she continued on as a Women’s Reproductive Health Research Scholar and Albert McKern Scholar for Perinatal Research. 

Dr. Han is board-certified in maternal-fetal medicine and obstetrics and gynecology. Her clinical and research interests intersect and include advanced prenatal diagnosis and management of fetal syndromes, management of complex maternal comorbidities, with a focus on diabetes and endocrine disorders in pregnancy, and preconception optimization of health. She has published 43 peer-reviewed manuscripts and 38 invited reviews and editorials.  Her clinical expertise will serve as a strong foundation for working with faculty to enhance the specialty care for individuals with high-risk pregnancies.  Currently, she is building multi-disciplinary programs for cardio-obstetrics, diabetes in pregnancy and advanced prenatal diagnosis and genetic screening. She has also expanded the outpatient maternal-fetal medicine consultation service to allow in-depth discussions and anticipatory guidance for patients with maternal or fetal comorbidities.

Dr. Han is also a passionate educator. While at the Center for Fetal Medicine, a rotation site for the UCLA fellows, she became the program director for the UCLA Maternal-Fetal Medicine Fellowship. Since assuming the role in 2017, she has expanded the clinical, research and didactic missions of the fellowship.  She is excited to leverage the continued advancement of the division to further enrich the experience for UCLA trainees.

Dr. Han is an active member of Society for Maternal-Fetal Medicine (SMFM), where she has field experience in leadership and program building.  She served as chair of the Internal Communications committee, and is currently the vice chair of the Education committee. Her additional roles in SMFM include serving on the national COVID-19 task force, tasked with rapid development of guidelines and educational materials for care of the obstetric patient during the pandemic, and being a member of the Finance Committee for the Foundation for SMFM.  She co-directs a well-attended “Rare maternal and fetal diseases” postgraduate course at the SMFM annual meeting, and produces the SMFM podcast series.  Additionally, she is involved in other national societies, including International Society of Prenatal Diagnosis, where she served in the program committee in 2020, and the American College of Obstetrics and Gynecology, where she is currently on the Prenatal Care Expert Consensus Panel, tasked with an evidence-based redesign of prenatal care.   

When considering the move to UCLA, her alma mater and academic home, Dr. Han said “I saw such potential for growth in the division, and the opportunity to carve out untapped clinical and research niches in the region. In conjunction with the superb faculty already here at UCLA, I plan to utilize my experience, expertise, and network to propel the UCLA maternal-fetal medicine division to become the world-class maternal-fetal medicine division that it will be.” 

Dr. Han will be seeing patients in all of our maternal-fetal medicine offices. When not working, she enjoys spending with her two children and husband, hiking, swimming, indoor cycling, tending to her vermicompost, attempting to garden, and traveling (and eating) their way around the world.  We are honored that Dr. Han is at UCLA and welcome her to the UCLA Health community.

Research Update 

Meet Sandra Orsulic, PhD, prominent cancer biologist whose 20 years of research has helped to shape research modeling of early ovarian cancer development

Sandra Orsulic

In January the UCLA Department of Obstetrics and Gynecology welcomed Dr. Sandra Orsulic to our faculty. Dr. Orsulic is a prominent cancer biologist

 whose work over the past 20 years has helped shape research modeling of early ovarian cancer development. After receiving her PhD from the University of North Carolina at Chapel Hill, Dr. Orsulic trained in the lab of Nobel Laureate Dr. Harold Varmus, and established her own laboratory research as Assistant Professor of Pathology at Harvard Medical School and Massachusetts General Hospital. For the last twelve years, Dr. Orsulic continued to grow her research portfolio at Cedars-Sinai Medical Center.

Research from Dr. Orsulic’s lab focuses on the development of mouse models in which ovarian cancers are induced and studied during its early stages of growth and metastatic progression. Her laboratory has generated multiple syngeneic mouse ovarian cancer cell lines with defined genetic alterations that recapitulate the development and pathophysiological manifestations of human ovarian cancer as well as the complexity of cancer-stroma interactions. Her team is using these models to determine the functional contributions of individual molecular pathways to cell transformation, immune response to cancer progression, recruitment of cancer-associated fibroblasts, and development of therapeutic resistance. Recent published efforts by the Orsulic lab are studying mechanisms by which the microenvironment contributes to cancer initiation and progression. This information is used to identify molecular markers for early cancer detection, and to generate functional models for testing targeted therapies.

Selected publications from Dr. Orsulic’s research include:

New and Noteworthy

UCLA faculty who have been recognized for excellence in clinical care, research and teaching

HONORS AND AWARDS:

UCLA pelvic medicine specialists Drs. Tamara Grisales, UCLA OBGYN Health Sciences Assistant Clinical Professor, Christopher Tarnay, UCLA OBGYN Health Sciences Associate Clinical Professor, Ja-Hong Kim, UCLA Urology Associate Professor, and the Center for Women's Pelvic Health group, were honored by UCLA Rehabilitation Services with a “Collaboration Award” during National Rehab Month. The FPMRS team was recognized for their support of the pelvic floor rehab program and ongoing collaboration. 

 

Sanaz Memarzadeh, MD, PhD, UCLA OBGYN Professor, was recognized by the Los Angeles County Board of Supervisors for her research and awareness building for ovarian cancer. She also received a Certificate of Recognition from Mayor Lindsey Horvath and the West Hollywood City Council for outstanding service, commitment, and accomplishments in ovarian cancer research.

Tina Nguyen, MD, UCLA OBGYN Health Sciences Assistant Clinical Professor, was named an Educator for Excellence for the David Geffen School of Medicine at UCLA for the 2020-21 academic year. A group of 30 accomplished and dedicated faculty teachers with expertise in small group facilitation and an outstanding track-record of exceptional teaching were selected. This program and group of faculty will be a transformative new element in our medical student education program.

Molly Quinn, MD, UCLA OBGYN Health Sciences Assistant Clinical Professor, has been named as a CREST Scholar by the Clinical Research/Reproductive Scientist Training (CREST) Program. This training program is offered by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the Clinical Research Training Program (CRTP) at Duke University, the American Society for Reproductive Medicine (ASRM), and the University of Colorado School of Medicine.  

Aparna Sridhar, MD, MPH, UCLA OBGYN Health Sciences Associate Clinical Professor, has been appointed as the Vice Chair for applied Anatomy College for David Geffen School of Medicine at UCLA. Additionally, in January 2020 she will assume the role of Clerkship Chair for the department.

GRANTS:

Yalda Afshar, MD, PhD, Assistant Professor In-Residence of Obstetrics and Gynecology in the Division of Maternal Fetal Medicine, has been awarded five grants in recent months. She is the Principal Investigator (PI) / MPI for “PRIORITY: Supporting the Public Health Response to COVID-19” funded by the Center for Disease Control (CDC) Foundation. She is one of four multiple principal investigators who received a Gates Foundation Grant, as well as a Robert Wood Johnson Foundation 2020 Global Ideas Grant. Dr. Afshar also received an Iris Cantor Women's Health Center Pilot Award for “PRIORITY (Pregnancy CoRonavIrus Outcomes RegisTrY” and a David Geffen School of Medicine Seed Grant for her project “Improving prenatal planning and postnatal care in severe congenital heart disease: Prenatal cardiac magnetic resonance (CMR) imaging in-utero to improve care for high-risk pregnancies.”

Marta Epeidegui, PhD, UCLA OBGYN Assistant Professor-In-Residence, recently received three NIH awards. She is the project director for “The role of PDL1+ exosomes in AIDS-related lymphoma,” a supplemental award to the UCLA Health Jonsson Comprehensive Cancer Center parent grant for which Michael Teitell, MD, PhD is the Principal Investigator. For the project “The Natural History of AIDS in Homosexual Men,” she is the co-investigator. Dr. Epeidegui is also the director of the biomarker core for the AMC clinical trials, a cooperative consortium to promote clinical trials in AIDS-related cancers.  

Deborah Krakow, MD, UCLA OBGYN Professor and Chair, received an NIH award for her project “Pregnancy and Osteogenesis Imperfecta.” This award includes Rashmi Rao, MD, Health Sciences Assistant Clinical Professor, as a co-investigator.

PRESENTATIONS:

Joshua Cohen, MD, UCLA OBGYN Health Sciences Assistant Clinical Professor:

  • C. Liao, K. Tran , M. Richardson, K. Darcy, C. Tiao, C.A. Hamilton, L. Maxwell, A. Mann, J. Cohen, D.S. Kapp, J. Chan. Increase in Uterine Serous Carcinoma: Will it Surpass Uterine Endometrioid Cancer? A population analysis of 720,984 uterine cancer patients. Oral poster presentation of the Annual Meeting of the International Gynecologic Cancer Society, September 10-13th, 2020.
  • C Liao, K Furey, M. Richardson, K Tran, C Tian, A Chan, K. Darcy, D.S. Kapp, JG. Cohen, John K. Chan. The rising incidence of cervical adenocarcinoma in the United States - who is most at risk?  Poster presentation of the Annual Meeting of the International Gynecologic Cancer Society, September 10-13th, 2020.
  • C Liao, K Furey, M. Richardson, K Tran, C Tian, A Chan, K. Darcy, D.S. Kapp, JG Cohen, John K. Chan. Increased Incidence of Cervical Adenosquamous Cell Carcinoma in Minority Populations?  Poster presentation of the Annual Meeting of the International Gynecologic Cancer Society, September 10-13th, 2020.
  • C Liao, K Furey, C. Chan, M. Richardson, K Tran, C Tian, Darcy, D.S. Kapp, JG Cohen, John K. Chan. Increased Incidence of Cervical Adenosquamous Cell Carcinoma in Minority Populations?   Poster presentation of the Annual Meeting of the International Gynecologic Cancer Society, September 10-13th, 2020.
  • C Liao, K Furey, C. Chan, M. Richardson, K Tran, C Tian, Darcy, D.S. Kapp, JG Cohen, John K. Chan. Disproportionate incidence of Neuroendocrine Cervical Cancer in Minority Populations - A study of 2,046 patients.    Poster presentation of the Annual Meeting of the International Gynecologic Cancer Society, September 10-13th, 2020.
  • M. Nakhla, A. Mandelbaum, R. Salani, P. Benharash, and JG Cohen. Frailty is Independently Associated with Worse Outcomes and Increased Resource Use Following Procedures to Treat Endometrial Cancer. Oral Plenary Presentation of the Annual Meeting of the International Gynecologic Cancer Society, September 10-13th, 2020

Daniel Dumesic, MD, UCLA OBGYN Professor:

  • Hoyos LR, Visser JA, McLuskey A, Chazenbalk GD, Grogan TR, Dumesic DA. Loss of Anti-Müllerian Hormone (AMH) Immunoactivity Due to a Homozygous AMH Gene Variant rs10417628 in a Woman with Classical Polycystic Ovary Syndrome (PCOS). Androgen Excess-PCOS Annual Meeting, November 7-8, 2020 
  • Leung KL, Sanchita S, Dumesic P, Ding X, Li X, Morselli M, Pellegrini M, Dumesic DA, Chazenbalk GD. Transcriptional Changes in Lipid Metabolism of Adipocytes Derived from Subcutaneous (SC) Abdominal Adipose Stem Cells (ASCs) of Normal-Weight Polycystic Ovary Syndrome (PCOS) Women. Androgen Excess-PCOS Annual Meeting, November 7-8, 2020. 
  • Dumesic DA, Tulberg A, Leung KL, Fisch SC, Grogan TR, Abbott, DH, Naik R, Chazenbalk GD. Subcutaneous abdominal stem cell adipogenesis predicts metabolic improvements in normal-weight polycystic ovary syndrome women. American Society for Reproductive Medicine 2020 Virtual Scientific Congress and Expo, San Diego, CA, October 17-21, 2020, Abstract O-100. 
  • Chazenbalk GD, Phan K, Dumesic DA. Chromatin accessibility, transcriptional networks, and fatty acid (FA) synthesis during adipogenesis in subcutaneous (SC) adipose stem cells (ASCs) of polycystic ovary syndrome (PCOS) women. American Society for Reproductive Medicine 2020 virtual Scientific Congress and Expo, San Diego, CA, October 17-21, 2020, Abstract O-246. 
  • Pham CT, Williams KJ, Leung KL, Lu GG, McNamara MV, Grogan TR, Dumesic DA, Chazenbalk GD. Total and De Novo Synthesis of Fatty Acids in Adipocytes Derived from Subcutaneous Abdominal Adipose Stem Cells of Normal-Weight Women with Polycystic Ovary Syndrome. Undergraduate Research Showcase, Undergraduate Research Week, May 18-22, 2020. 
  • Tulberg A, Naik R, Sanchita S, Grogan TR, Chazenbalk GD, Dumesic D. Subcutaneous Abdominal Adipocyte Stem Cell Development to Adipocytes In Vitro Predicts Metabolic Differences in Normal-Weight Women with and Without Polycystic Ovary Syndrome. Undergraduate Research Showcase, Undergraduate Research Week, May 18-22, 2020. 

Sandra Orsulic, PhD, UCLA OBGYN Professor-In-Residence:

  • New Tools for the Study of Fallopian Tubes from BRCA1 Mutation Carriers. DNA Repair and Model Systems. AACR-Rivkin Virtual Ovarian Cancer Research Seminar Series. September 10, 2020.

Molly Quinn, MD, UCLA OBGYN Health Sciences Assistant Clinical Professor:

  • Shapiro AJ and Quinn MM. Patient experience with expanded-carrier screening: adequacy of provider counseling, economic burden and decision-making regarding partner testing. Oral Presentation. American Society for Reproductive Medicine Annual Conference. October 2020, Virtual Conference. 
  • Mehr H, Lee V, Jackson-Bey T, Herndon C, Quinn MM. Reading level of patient education material on infertility clinic websites is above national recommendations. Oral Presentation. American Society for Reproductive Medicine Annual Conference. October 2020, Virtual Conference. 
  • Hariton E, Morris J, Kao C-N, Jaswa E, Quinn MM, Cedars MI, Huddleston HG. An AMH-based screening tool is both sensitive and specific for predicting a diagnosis of PCOS by Rotterdam Criteria. Oral Presentation. American Society for Reproductive Medicine Annual Conference. October 2020, Virtual Conference. 
  • Riestenberg C, Quinn MM, Akopians A, Danzer H, Surrey S, Ghadir S, Kroener L. Endometrial compaction does not predict ongoing pregnancy rate in programmed single euploid embryo transfer cycles. Poster Presentation. American Society for Reproductive Medicine Annual Conference. October 2020, Virtual Conference. 
  • Dilday EA, Hoyos LR, Quinn MM, Kroener LL. Luteal phase support with progesterone does not improve pregnancy rates in patients undergoing controlled ovarian stimulation with letrozole. Poster Presentation. American Society for Reproductive Medicine Annual Conference. October 2020, Virtual Conference. 
  • Mehr H, Jackson-Bey T, Vu M, Lee V, Herndon C, Ho J, Aghajanova L, Quinn MM. We are here for you: Infertility clinic website communication during the escalating stages of the COVID-19 pandemic. Poster Presentation. American Society for Reproductive Medicine Annual Conference. October 2020, Virtual Conference. 

Andrea Rapkin, MD, UCLA OBGYN Professor:

Aparna Sridhar, MD, MPH, UCLA OBGYN Health Sciences Associate Clinical Professor

  • E Chan, Y Korotkaya, A Sridhar. Analysing Patient Experiences from Crowd-Sourced Reviews of Crisis Pregnancy Centers in California. E-poster.  American College of Obstetrics and Gynecologists. October 2020, Virtual Conference.

PUBLICATIONS:

For a list of recent publications

UCLA OBGYN Recent Publications

  • Monni G, Corda V, Iuculano A, Afshar Y.The Decline of of Amniocentesis and the Increase of Chorionic Villus Sampling in Modern Perinatal Medicine. Journal of Perinatal Medicine, 2020, Ahead of Print, PMID: 32187015. 
  • Mei J, Negi M, Han CS, Rao R, Krakow D, Afshar Y.Gender Representation of Speakers at the Society for Maternal Fetal Medicine Postgraduate Courses: a 20-year Review. Am J Obstet Gynecol MFM. Accepted, In Press. 10.1016/j.ajogmf.2020.100131. Ahead of print, 2020. 
  • Pluym ID, Rao R, Ballas J, Ramos GA, Cross SN, Zapata M, Srinivas S, Louis JM, Werner E, Afshar Y, Han CS. Obstetrical Unit Response to the CoVID-19 Pandemic: “OUR” Study. Am J Perinatology. 2020 Sep 6. doi: 10.1055/s-0040-1715861. Ahead of Print. PMID: 32892329.  
  • Mei JY, Munoz H, Szlachta-McGinn A, Rao R, Datkhaeva I, Han CS, Afshar Y. Rates of Cesarean Conversion and Associated Predictors and Outcomes in Planned Vaginal Twin Deliveries. Am J Perinatology. Oct 8. doi: 10.1055/s-0040-1718368. Online ahead of print. PMID: 33032326 
  • Rose K, Mei J, Datkhaeva I, Kwan L, Zhang H, Han CS, Afshar Y. Preferences and comfort of maternal fetal medicine fellows in the United States with operative deliveries.  J Maternal Neonatal Fetal Medicine. 2020 Sept 10: 1-6. doi: 10.1080/14767058.2020.1817894. Online ahead of print. PMID: 32912038.  
  • Flaherman VJ, Afshar Y, Boscardin J, Keller RL, Mardy An, Prahl MK, Phillips C, Asiodu IV, Berghella V, Chambers BD, Crear-Perry J, Jamieson Dm, Jacoby VL, Gaw SL. Infant Outcomes Following Maternal Infection with SARS-CoV-2: First Report from the PRIOIRTY study. Clinical Infectious Disease. 2020 Sept 18: doi. 10.1093/cid/ciaa1411. Online ahead of print. PMID: 32947612 
  • Sarkar M, Pilar Hernandez MD, Brady CW, Carla W. Brady,  Fleckenstein J, Forde, JA, Khungar V, Molleston JP, Afshar Y, Terrault NA. Reproductive Health and Liver Disease: Practice Guidance by the American Association for the Study of Liver Diseases. 2020 Sept 18. doi: 10.1002/hep.31559. Online ahead of print. PMID: 32946672.  
  • Afshar Y, Gaw S, Flaherman V, Chambers B, Krakow D, Berghella V, Shamshirsaz A, Aldrovandi G, Greiner A, Riley L, Boscardin WJ, Jamieson D, Jacoby V. Clinical Presentation of Coronavirus 2019 (CoVID-19) in Pregnant and Recently Pregnant People. Obstetrics and Gynecology, 2020 Oct 7. doi: 10.1097/AOG.0000000000004178. Epub ahead of print. PMID: 33027186. 
  • Sarkar M, Brady CW, Fleckenstein J, Forde KA, Khungar V, Molleston JP, Afshar Y, Terrault NA. Reproductive Health and Liver Disease: Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2020 Sep 18. doi: 10.1002/hep.31559. Epub ahead of print. PMID: 32946672.
  • Afshar Y, Silverman N, Han CS, Platt LD. Clinical Guidance and Perinatal Care in the Era of Coronavirus 2019 (COVID-19). J Perinatal Medicine. In Press, 2020.  J Perinat Med. 2020 Oct 9:/j/jpme.ahead-of-print/jpm-2020-0400/jpm-2020-0400.xml. doi: 10.1515/jpm-2020-0400. Online ahead of print. PMID: 33035193. 
  • Pluym ID, Holliman K, Afshar Y, Lee Mha CC, Richards MC, Han CS, Krakow D, Rao R. Emergency Department Use Among Postpartum Women with Mental Health Disorders. Am J Obstet Gynecol MFM. 2020 Oct 20:100269. doi: 10.1016/j.ajogmf.2020.100269. Epub ahead of print. PMID: 33103100; PMCID: PMC7574686.
  • Douglass KM, Strobel KM, Richley M, Mok T, de St Maurice A, Fajardo V, Young AT, Rao R, Lee L, Benharash P, Chu A, Afshar Y. Maternal-Neonatal Dyad Outcomes of Maternal COVID-19 Requiring Extracorporeal Membrane Support: A Case Series. Am J Perinatol. 2020 Oct 17. doi: 10.1055/s-0040-1718694. Epub ahead of print. PMID: 33069171.
  • Monni G, Corda V, Iuculano A, Afshar Y. Efficacy, safety, and success of 18- versus 20-gauge needle for transabdominal chorionic villus sampling in a high-volume training setting. Prenat Diagn. 2020 Oct 16. doi: 10.1002/pd.5845. Epub ahead of print. PMID: 33067848.
  • Mei JY, Mallampati, D,  Pluym, ID, Han CS, Afshar Y. Twin Vaginal Deliveries in Labor Rooms: A Cost-Effectiveness Analysis. Am J Perinatology, Accepted, In Press, 
  • Mok T, Contreras D, Chmait R, Goldstein J, Pluym I, Tabsh K, Aldrovandi G, Afshar Y. Complicated Monochorionic-Diamniotic Twins in a Pregnant Women with SARS-CoV-2 Infection in the Second Trimester. Am J Perinatology, Accepted, In Press, 
  • Mardock, A. L., Rudasill, S. E., Lai, T. S., Sanaiha, Y., Wong, D. H., Sinno, A. K., P Benharash,Cohen, JG. Readmissions after ovarian cancer cytoreduction surgery: The first 30 days and beyond. Journal of Surgical Oncology, July 2020, Ahead of online print. doi: 10.1002/jso.26137 
  • Manrriquez, E., Mandelbaum, A., Aguayo, E., Zakhour, M., Karlan, B., Benharash, P, and Cohen, JG. Factors associated with high-cost hospitalizations in elderly ovarian cancer patients. Gynecologic Oncology, September 2020. Online ahead of print.  10.1016/j.ygyno.2020.09.026
  • Cinar, P., Bold, R., Bosslet, B. A., Bota, D. A., Burgess, D., Chew, H. K.,Cohen JG, Elquza, E, Gold, K, Kamiya, E, Karlan, BY, McKay, Rana, Patel, S, Ternaan, K, Welborn, J, Yamamoto, M, and Rugo, H. Planning for post-pandemic cancer care delivery: Recovery or opportunity for redesign?. CA: A Cancer Journal for Clinicians, September 2020. Online ahead of print. DOI: 10.3322/caac.21644 
  • Zsiros, E,Cohen JG, and Zweizig, S.  Gynecologic Oncology Considerations During the Covid-19 Pandemic, 3/23/2020
  • Cohen JG, Shanin, M, Holtz, D, and Zweizig, S. Telemedicine Considerations During the Covid-19 Pandemic, 4/1/2020
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  • Hoyos LR, Visser JA, Mcluskey A, Chazenbalk GD, Grogan TR, Dumesic DA.Loss of anti-mullerian hormone (AMH) immunoreactivity due to a homozygous AMH gene mutation rs10417628 in a woman with classical polycystic ovary syndrome (PCOS). Human Reprod 2020, in press. doi: 10.1093/humrep/deaa199 PMID 32918081 
  • Dumesic DA, Tulberg A, Leung KL, Fisch SC, Grogan TR, Abbott DH, Naik R, Chazenbalk GD. Accelerated Subcutaneous Abdominal Stem Cell Adipogenesis Predicts Insulin Sensitivity in Normal-Weight Polycystic Ovary Syndrome Women. Fertil Steril, in press. 
  • Leung KL, Sanchita S, Pham CT, Davis BA, Okhovat M, Ding X, Dumesic P, Grogan TR, Williams KJ, Morselli M, Ma F, Carbone L, Li X, Pellegrini M, Dumesic D, Chazenbalk GD. Dynamic Changes in Chromatin Accessibility, Altered Adipogenic Gene Expression, and Total vs De Novo Fatty Acid Synthesis in Subcutaneous Adipose Stem Cells of Normal-Weight Polycystic Ovary Syndrome (PCOS) Women During Adipogenesis: Evidence of Cellular Programming. Clinical Epigenetics, in press.
  • Dumesic DA, Wood JR, Abbott DH, Strauss III, JF. A Primate Perspective on Oocytes and Transgenerational PCOS. Reprod Biomed Online 2020;40(6):765-767PMID: 32312513. 
  • Stener-Victorin E, Padmanabhan P, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA,Abbott DH. Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocr Rev. 2020;41:538-576. PMID: 32310267 
  • Abbott DH, Levine JE, Dumesic DA. Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome? Endocrinology 2020 Aug 1;161(8); doi: 10.1210/endocr/bqaa095. PMID 32530028.
  • Puttabyatappa M, Dou J, Guo X, Dumesic D, Bakulski KM, Padmanabhan V.Developmental Programming: Granulosa and Theca Cell-Specific Transcriptional Regulation by Prenatal Testosterone in Sheep. Endocrinology 2020;161(8);1-17. doi: 10.1210/endocr/bqaa094. PMID 32516392
  • Hoyos LR, Putra M, Armstrong AA, Cheng CY, Riesenberg C, Schooler TA, Dumesic D. Measures of patient dissatisfaction with health care in polycystic ovary syndrome: retrospective analysis. J Med Internet Res 2020;22(4):e16541. doi: 10.2196/16541. PubMed PMID: 32314967 PMCID7201322
  • Mei JY, Mallampati D, Pluym ID,Han CS, Afshar Y. Twin vaginal deliveries in labor rooms: A cost-effectiveness analysis. Am J Perinat. Minor revisions.  
  • Mei J, Deshmukh U, Negi M, Campbell K, Paidas MJ, Platt LD, Silverman NS,Han CS. May-Thurner Syndrome in Pregnancy: A Multi-Institutional Case Series and Review of the Literature. Am J Obstet Gynecol MFM. doi: 1016/j.ajogmf.2020.100240 
  • Pluym ID, Holliman K, Afshar Y, Lee CC, Richards M,Han CS, Krakow DK, Rao R. Emergency Department Use Among Postpartum Women with Mental Health Disorders. Am J Obstet Gynecol MFM. In press. doi: 10.1016/j.ajogmf.2020.100269 
  • Afshar Y, Silverman NS,Han CS, Platt LD. Clinical Guidance and Perinatal Care in the Era of Coronavirus Disease 2019 (CoVID-19). J Perinatol Med. Oct 2020.  doi: 10.1515/jpm-2020-0400.  
  • Mei J, Munoz HE, Kim JS, Szlachta-McGinn A, Blat C, Rao R,Han CS, Irani RA, Afshar Y. Rates of Cesarean Conversion and Associated Predictors and Outcomes in Planned Vaginal Twin Deliveries. Am J Perinatol. 2020 Oct. DOI: 10.1055/s-0040-1718368. 
  • Johnson J, Melvin E, Srinivas SK, Louis JM, Hughes B,Han CS, Norton ME, Werner EF.  COVID-19 Testing, Personal Protective Equipment, and Staffing Strategies Vary at Obstetrics Centers across the Country. Am J Perinatol. Sept 2020.  DOI: 10.1055/s-0040-1718401 
  • Rose K, Kwan L, Zhang H,Han CS, Afshar Y. Preferences and comfort of maternal fetal medicine fellows in the United States with operative vaginal deliveries. J Mat Fet Med. 2020 Sep 10;1-6. DOI:10.1080/14767058.2020.1817894 
  • Pluym ID, Rao R, Ballas J, Ramos GA, Cross SN, Zapata M, Srinivas S, Louis JM, Werner EF, Afshar Y,Han CS. Obstetrical Unit Response to the CoVID-19 Pandemic: “OUR” Study. Am J Perinatol. 2020 Sept. 37(13): 1301-1309. PMID: 32892329. DOI: 1055/s-0040-1715861 
  • Duzyj CM, Thornburg LL,Han CS.  Clinical Expert Series: Practice Modification for Pandemics- A Model for Surge Planning in Obstetrics. Obstet Gynecol. 2020 Aug;136(2). DOI: 10.1097/AOG.0000000000004004.  
  • Mei J, Negi M,Han CS, Krakow D, Afshar Y. Gender Representation of Speakers at the Society for Maternal Fetal Medicine Postgraduate Courses: a 20-year review.  Am J Obstet Gynec MFM. 2020 Aug. 2(3):100131. https://doi.org/10.1016/j.ajogmf.2020.100131.  
  • Richley M, Han CS. Insulin pumps and continuous glucose monitors.  Contemp Obstet Gynecol. 2020 Nov.
  • Kashanian A, Chan J, Mukherjee D, Pressman BD,Krakow D, Danielpour M.Improvement in ventriculomegaly following cervicomedullary decompressive surgery in children with achondroplasia and foramen magnum stenosis  Am J Med Genet A. 2020 Jun 11
  • Afshar Y, Gaw SL, Flaherman VJ, Chambers BD, Krakow D, Berghella V, Shamshirsaz AA, Boatin AA, Aldrovandi G, Greiner A, Riley L, Boscardin WJ, Jamieson DJ, Jacoby VL. Clinical Presentation of Coronavirus Disease 2019 (COVID-19) in Pregnant and Recently Pregnant People.Obstet Gynecol. 2020 Oct 7
  • Pluym ID, Holliman K, Afshar Y, Lee Mha CC, Richards MC, Han CS, Krakow D, Rao R. Pluym ID. Emergency Department Use Among Postpartum Women with Mental Health Disorders. Am J Obstet Gynecol MFM. 2020 Oct 20:100269
  • BosakovaM, Abraham SP, Nita A, Hruba E, Buchtova M, Taylor SP, Duran I, Martin J, Svozilova K, Barta T, Varecha M, Balek L, Kohoutek J, Radaszkiewicz T, Pusapati GV, Bryja V, Rush ET, Thiffault I,. NickersonDA, Bamshad MJ, University of Washington Center for Mendelian Genomics, Rohatgi R, Cohn DH, Krakow D*, Krejci P*. Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling. EMBO Molecular Medicine, in press, 9/2020 (cover)
  • BaradM, Csukasi F, Kunova-Bosakova M, Martin J, Zhang W, TaylorSP, Lachman RS, Jennifer Zieba Z, Bamshad M, Nickerson DA, ChongJX, Cohn DH, Krejci P, Krakow D*,Duran I. Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia. EBioMed, in-press, 10/1/2020, *corresponding author
  • Carrie Riestenberg, Molly Quinn, Alin Akopians, Hal Danzer, Mark Surrey, Lindsay Kroener. Endometrial compaction does not predict live birth rate in single euploid frozen embryo transfer cycles. Journal of Assisted Reproduction and Genetics. 03 January 2021.
  • Sonni I, Lee-Felker S, Memarzadeh S, et al.68Ga-FAPi-46 diffuse bilateral breast uptake in a patient with cervical cancer after hormonal stimulation [published online ahead of print, 2020 Jul 10]. Eur J Nucl Med Mol Imaging. 2020;10.1007/s00259-020-04947-z. doi:10.1007/s00259-020-04947-z
  • Kang Y, Kim TH, Gjertson DW, Cohen J, Memarzadeh S, Moatamed NA.The pathology of endometrial carcinomas in relation to the sentinel lymph nodes. In Press (PLOS One)
  • Dual targeting of GSK3B and HDACs reduces tumor growth and improves survival in an ovarian cancer mouse model.Taylan E, Zayou F, Murali R, Karlan BY, Pandol SJ, Edderkaoui M,Orsulic S. Gynecol Oncol. 2020 Oct;159(1):277-284. doi: 10.1016/j.ygyno.2020.07.005. Epub 2020 Jul 19.PMID: 32698955 Free article.
  • Are Epithelial Ovarian Cancers of the Mesenchymal Subtype Actually Intraperitoneal Metastases to the Ovary?Hu Y, Taylor-Harding B, Raz Y, Haro M, Recouvreux MS, Taylan E, Lester J, Millstein J, Walts AE, Karlan BY,Orsulic S. Front Cell Dev Biol. 2020 Jul 17;8:647. doi: 10.3389/fcell.2020.00647. eCollection 2020.PMID: 32766252 Free PMC article.
  • HOXB13 controls cell state through super-enhancers.Aspuria PJ, Cheon DJ, Gozo MC, Beach JA, Recouvreux MS, Walts AE, Karlan BY,Orsulic S.Exp Cell Res. 2020 Aug 1;393(1):112039. doi: 10.1016/j.yexcr.2020.112039. Epub 2020 May 4.PMID: 32376288 Free article.
  • Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers.Glubb DM, Thompson DJ, Aben KK, Alsulimani A, Amant F, Annibali D, Attia J, Barricarte A, Beckmann MW, Berchuck A, Bermisheva M, Bernardini MQ, Bischof K, Bjørge L, Bodelon C, Brand AH, Brenton JD, Brinton LA, Bruinsma F, Buchanan DD, Burghaus S, Bützow R, Cai H, Carney ME, Chanock SJ, Chen C, Chen X, Chen Z, Cook LS, Cunningham JM, De Vivo I, DeFazio A, Doherty JA, Dork T, du Bois A, Dunning AM, Durst M, Edwards T, Edwards RP, Ekici AB, Ewing A, Fasching PA, Ferguson S, Flanagan JM, Fostira F, Fountzilas G, Friedenreich CM, Gao B, Gaudet MM, Gawelko J, Gentry-Maharaj A, Giles GG, Glasspool R, Goodman MT, Gronwald J, Harris HR, Harter P, Hein A, Heitz F, Hildebrandt MAT, Hillemanns P, Høgdall E, Høgdall CK, Holliday EG, Huntsman DG, Huzarski T, Jakubowska A, Jensen A, Jones ME, Karlan BY, Karnezis A, Kelley JL, Khusnutdinova E, Killeen JL, Kjaer SK, Klapdor R, Köbel M, Konopka B, Konstantopoulou I, Kopperud RK, Koti M, Kraft P, Kupryjanczyk J, Lambrechts D, Larson MC, Le Marchand L, Lele S, Lester J, Li AJ, Liang D, Liebrich C, Lipworth L, Lissowska J, Lu L, Lu KH, Macciotta A, Mattiello A, May T, McAlpine JN, McGuire V, McNeish IA, Menon U, Modugno F, Moysich KB, Nevanlinna H, Odunsi K, Olsson H,Orsulic S, Osorio A, Palli D, Park-Simon TW, Pearce CL, Pejovic T, Permuth JB, Podgorska A, Ramus SJ, Rebbeck TR, Riggan MJ, Risch HA, Rothstein JH, Runnebaum IB, Scott RJ, Sellers TA, Senz J, Setiawan VW, Siddiqui N, Sieh W, Spiewankiewicz B, Sutphen R, Swerdlow AJ, Szafron LM, Teo SH, Thompson PJ, Thomsen LCV, Titus L, Tone A, Tumino R, Turman C, Vanderstichele A, Velez Edwards D, Vergote I, Vierkant RA, Wang Z, Wang-Gohrke S, Webb PM, White E, Whittemore AS, Winham SJ, Wu X, Wu AH, Yannoukakos D, Spurdle AB, O'Mara TA. Cancer Epidemiol Biomarkers Prev. 2020 Nov 3:cebp.0739.2020. doi: 10.1158/1055-9965.EPI-20-0739. Online ahead of print.PMID: 33144283
  • Editorial: The Tumor Microenvironment: Recent Advances and Novel Therapeutic Approaches.Korkaya H,Orsulic S. Front Cell Dev Biol. 2020 Sep 17;8:586176. doi:10.3389/fcell.2020.586176. eCollection 2020.PMID: 33043018 Free PMC article. No abstract available.
  • Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium.Martins FC, Couturier DL, Paterson A, Karnezis AN, Chow C, Nazeran TM, Odunsi A, Gentry-Maharaj A, Vrvilo A, Hein A, Talhouk A, Osorio A, Hartkopf AD, Brooks-Wilson A, DeFazio A, Fischer A, Hartmann A, Hernandez BY, McCauley BM, Karpinskyj C, de Sousa CB, Høgdall C, Tiezzi DG, Herpel E, Taran FA, Modugno F, Keeney G, Nelson G, Steed H, Song H, Luk H, Benitez J, Alsop J, Koziak JM, Lester J, Rothstein JH, de Andrade JM, Lundvall L, Paz-Ares L, Robles-Díaz L, Wilkens LR, Garcia MJ, Intermaggio MP, Alcaraz ML, Brett MA, Beckmann MW, Jimenez-Linan M, Anglesio M, Carney ME, Schneider M, Traficante N, Pejovic N, Singh N, Le N, Sinn P, Ghatage P, Erber R, Edwards R, Vierkant R, Ness RB, Leung S,Orsulic S, Brucker SY, Kaufmann SH, Fereday S, Gayther S, Winham SJ, Kommoss S, Pejovic T, Longacre TA, McGuire V, Rhenius V, Sieh W, Shvetsov YB, Whittemore AS, Staebler A, Karlan BY, Rodriguez-Antona C, Bowtell DD, Goode EL, Høgdall E, Candido Dos Reis FJ, Gronwald J, Chang-Claude J, Moysich KB, Kelemen LE, Cook LS, Goodman MT, Fasching PA, Crawford R, Deen S, Menon U, Huntsman DG, Köbel M, Ramus SJ, Pharoah PDP, Brenton JD. Br J Cancer. 2020 Sep;123(5):793-802. doi: 10.1038/s41416-020-0900-0. Epub 2020 Jun 18.PMID: 32555365 Free PMC article.
  • Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).Talhouk A, George J, Wang C, Budden T, Tan TZ, Chiu DS, Kommoss S, Leong HS, Chen S, Intermaggio MP, Gilks B, Nazeran TM, Volchek M, Elatre W, Bentley RC, Senz J, Lum A, Chow V, Sudderuddin H, Mackenzie R, Leong SCY, Liu G, Johnson D, Chen B, Group A, Alsop J, Banerjee SN, Behrens S, Bodelon C, Brand AH, Brinton L, Carney ME, Chiew YE, Cushing-Haugen KL, Cybulski C, Ennis D, Fereday S, Fortner RT, García-Donas J, Gentry-Maharaj A, Glasspool R, Goranova T, Greene CS, Haluska P, Harris HR, Hendley J, Hernandez BY, Herpel E, Jimenez-Linan M, Karpinskyj C, Kaufmann SH, Keeney GL, Kennedy CJ, Köbel M, Koziak JM, Larson MC, Lester J, Lewsley LA, Lissowska J, Lubinski J, Luk H, Macintyre G, Mahner S, McNeish IA, Menkiszak J, Nevins N, Osorio A, Oszurek O, Palacios J, Hinsley S, Pearce CL, Pike MC, Piskorz AM, Ray-Coquard I, Rhenius V, Rodriguez-Antona C, Sharma R, Sherman ME, De Silva D, Singh N, Sinn P, Slamon D, Song H, Steed H, Stronach EA, Thompson PJ, Toloczko A, Trabert B, Traficante N, Tseng CC, Widschwendter M, Wilkens LR, Winham SJ, Winterhoff B, Beeghly-Fadiel A, Benitez J, Berchuck A, Brenton JD, Brown R, Chang-Claude J, Chenevix-Trench G, deFazio A, Fasching PA, García MJ, Gayther SA, Goodman MT, Gronwald J, Henderson MJ, Karlan BY, Kelemen LE, Menon U,Orsulic S, Pharoah PDP, Wentzensen N, Wu AH, Schildkraut JM, Rossing MA, Konecny GE, Huntsman DG, Huang RY, Goode EL, Ramus SJ, Doherty JA, Bowtell DD, Anglesio MS. Clin Cancer Res. 2020 Oct 15;26(20):5411-5423. doi: 10.1158/1078-0432.CCR-20-0103. Epub 2020 Jun 17.PMID: 32554541
  • Prognostic gene expression signature for high-grade serous ovarian cancer.Millstein J, Budden T, Goode EL, Anglesio MS, Talhouk A, Intermaggio MP, Leong HS, Chen S, Elatre W, Gilks B, Nazeran T, Volchek M, Bentley RC, Wang C, Chiu DS, Kommoss S, Leung SCY, Senz J, Lum A, Chow V, Sudderuddin H, Mackenzie R, George J; AOCS Group, Fereday S, Hendley J, Traficante N, Steed H, Koziak JM, Köbel M, McNeish IA, Goranova T, Ennis D, Macintyre G, Silva De Silva D, Ramón Y Cajal T, García-Donas J, Hernando Polo S, Rodriguez GC, Cushing-Haugen KL, Harris HR, Greene CS, Zelaya RA, Behrens S, Fortner RT, Sinn P, Herpel E, Lester J, Lubinski J, Oszurek O, Toloczko A, Cybulski C, Menkiszak J, Pearce CL, Pike MC, Tseng C, Alsop J, Rhenius V, Song H, Jimenez-Linan M, Piskorz AM, Gentry-Maharaj A, Karpinskyj C, Widschwendter M, Singh N, Kennedy CJ, Sharma R, Harnett PR, Gao B, Johnatty SE, Sayer R, Boros J, Winham SJ, Keeney GL, Kaufmann SH, Larson MC, Luk H, Hernandez BY, Thompson PJ, Wilkens LR, Carney ME, Trabert B, Lissowska J, Brinton L, Sherman ME, Bodelon C, Hinsley S, Lewsley LA, Glasspool R, Banerjee SN, Stronach EA, Haluska P, Ray-Coquard I, Mahner S, Winterhoff B, Slamon D, Levine DA, Kelemen LE, Benitez J, Chang-Claude J, Gronwald J, Wu AH, Menon U, Goodman MT, Schildkraut JM, Wentzensen N, Brown R, Berchuck A, Chenevix-Trench G, deFazio A, Gayther SA, García MJ, Henderson MJ, Rossing MA, Beeghly-Fadiel A, Fasching PA,Orsulic S, Karlan BY, Konecny GE, Huntsman DG, Bowtell DD, Brenton JD, Doherty JA, Pharoah PDP, Ramus SJ. Ann Oncol. 2020 Sep;31(9):1240-1250. doi: 10.1016/j.annonc.2020.05.019. Epub 2020 May 28.PMID: 32473302 Free PMC article.
  • Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors.Lahiguera Á, Hyroššová P, Figueras A, Garzón D, Moreno R, Soto-Cerrato V, McNeish I, Serra V, Lazaro C, Barretina P, Brunet J, Menéndez J, Matias-Guiu X, Vidal A, Villanueva A, Taylor-Harding B, Tanaka H,Orsulic S, Junza A, Yanes O, Muñoz-Pinedo C, Palomero L, Pujana MÀ, Perales JC, Viñals EMBO Mol Med. 2020 Jun 8;12(6):e11217. doi: 10.15252/emmm.201911217. Epub 2020 May 13.PMID: 32400970 Free PMC article.
  • Pluym ID,Holliman K, Afshar Y, Lee CC, Richards MC, Han CS, Krakow D, Rao R. Emergency Department Use Among Postpartum Women with Mental Health Disorders. Am J Obstet Gynecol MFM. 2020 Oct 20. E-pub ahead of print. 
  • Sparks TN, Lianoglou BR, Adami R,Pluym ID, Holliman K, Duffy J, Downum S, Patel S, Faubel A, Boe NM, Field NT, Murphy A, Laurent LC, Jolley J, Uy Ch, Slavotinek AM, Devine P, Hodoglugil U, Van Ziffle J, Sanders SJ, MacKenzie TC, Norton ME on behalf of the University of California Fetal-Maternal Consortium and the UCSF Center for Maternal-Fetal Precision Medicine. Exome Sequencing for Prenatal Diagnosis in Non-immune Hydrops Fetalis. N Engl J Med. 2020 Oct 7. 
  • Rose K, Mei J, Kwan L,Pluym ID, Han CS, Afshar Y. Preferences and comfort of maternal fetal medicine fellows in the United States with operative vaginal deliveries. J Matern-Fetal Neonatal Med. 2010 Sep 10. E-pub ahead of print. 
  • Pluym ID,Rao R, Ballas J, Ramos GA, Cross SN, Zapata M, Srinivas S, Louis JM, Werner E,  Afshar Y, Han CS. Obstetrical Unit Response to the CoVID-19 Pandemic: OUR Study. Am J  Perinatol. 2020 Sep 6.  
  • Pluym ID,Afshar Y, Holliman K, Kwan L, Bolagan A, Mok T, Silver B, Ramirez E, Han CS,  
    Platt LD. Accuracy of three-dimensional automated ultrasound imaging of biometric measurements of the fetal brain. Ultrasound Obstet Gynecol. 2020 Aug 8.  
  • Kaing A, Rosen MP, Quinn MM. Perceptions, motivations, and decision regret surrounding preimplantation genetic testing for aneuploidy Hum Reprod2020; 35(9):2047-57. 
  • Riestenberg C, Kroener L, Quinn MM, Ching K, Ambartsumyan G. Routine endometrial receptivity array in first embryo transfer cycles does not improve live birth rate Fertil Steril2020; in press. 
  • Han YM, Grenert JP, Wiita AP, Quinn M, Fujimoto VY, Rabban JT. Prevalence of partial hydatidiform mole in products of conception from gestations with fetal triploidy merits reflex genotype testing independent of the morphologic appearance of the chorionic villi. Am J Surg Pathol2020; 44(6):849-58. Pubmed ID:32205485 
  • Pluym ID, Holliman K, Afshar Y, Lee Mha CC, Richards MC, Han CS, Krakow D,Rao R.Emergency Department Use Among Postpartum Women with Mental Health Disorders. American Journal of Obstetrics and Gynecology Maternal Fetal Medicine, 2020 PMID: 33102100 
  • Douglass KM, Strobel KM, Richley M, Mok T, de St Maurice A, Fajardo V, Young AT,Rao R, Lee L, Benharash P, Chu A, Afshar Y. Maternal-Neonatal Dyad Outcomes of Maternal COVID-19 Requiring Extracorporeal Membrane Support: A Case Series. American Journal of Perinatology, 2020 PMID: 33069171 
  • Mei JY, Munoz HE, Kim JS, Szlachta-McGinn A, Blat C,Rao R, Han CS, Irani RA, Afshar Y. Rates of Cesarean Conversation and Associated Predictors and Outcomes in Planned Vaginal Twin Deliveries. American Journal of Perinatology, 2020 PMID: 33032326 
  • Pluym ID,Rao R, Ballas J, Ramos GA, Cross SN, Zapata M, Srinivas S, Louis JM, Werner E, Afshar Y, Han CS. Obstetrical Unit Response to the COVID-19 Pandemic: OUR Study. American Journal of Perinatology, 2020 PMID: 32892329 
  • Lee E, Pluym ID, Wong D, Kwan L, Varma V,Rao R. The impact of state legalization on rates of marijuana use in pregnancy in a universal drug screening population. Journal of Maternal Fetal Neonatal Medicine, 2020. PMID: 32419547 
  • Ha TK,Rao R, Maykin M, Mei JY, Havard A, Gaw SL. Vaginal birth after Cesarean: Does accuracy of predicted success change from prenatal intake to admission? American Journal of Obstetrics and Gynecology Maternal Fetal Medicine, 2020  
  • Pluym ID, Paek B, Walker M, Liu H, Kwan L,Rao R, Scibetta E, Afshar Y, Holliman K, Wong T, Platt LD, Han CS. Novel Use of a Social-Media-Based Survey to Detect Regional Differences in Management of Monochorionic-Diamniotic Twins. American Journal of Perinatology, 2020 PMID: 32000293 
  • Black and Hispanic women are less likely than white women to receive guideline-concordant endometrial cancer treatment.Kaspers M, Llamocca E, Quick A, Dholakia J,Salani R, Felix AS. Am J Obstet Gynecol. 2020 Sep;223(3):398.e1-398.e18. doi: 10.1016/j.ajog.2020.02.041. Epub 2020 Mar 3.PMID: 32142825
  • An Ecological Evaluation of the Increasing Incidence of Endometrial Cancer and the Obesity Epidemic.Smrz SA, Calo C, Fisher JL,Salani R. Am J Obstet Gynecol. 2020 Oct 27:S0002-9378(20)31272-2. doi: 10.1016/j.ajog.2020.10.042. Online ahead of print.PMID: 33127429
  • Feasibility of implementing a text-based symptom-monitoring program of endometrial, ovarian, and breast cancer patients during treatment.Naughton MJ,Salani R, Peng J, Lustberg M, DeGraffinreid C, Moon J, Loyan H, Beverly Hery CM, Paskett ED. Qual Life Res. 2020 Oct 14. doi: 10.1007/s11136-020-02660-w. Online ahead of print.PMID: 33052514
  • Pathologic chemotherapy response score in epithelial ovarian cancer: Surgical, genetic, and survival considerations.Barrington DA, Felix AS, Owda R, Suarez AA, Cohen DW, Senter L, Copeland LJ, Fowler JM, Backes FJ, Cohn DE, Bixel KL, O'Malley DM,Salani R, Cosgrove CM. Surg Oncol. 2020 Sep;34:40-45. doi: 10.1016/j.suronc.2020.03.001. Epub 2020 Mar 11.PMID: 32891351
  • Circulating Tumor Cells In Advanced Cervical Cancer: NRG Oncology-Gynecologic Oncology Group Study 240 (NCT 00803062).Tewari KS, Sill MW, Monk BJ, Penson RT, Moore DH, Lankes HA, Ramondetta LM, Landrum LM, Randall LM, Oaknin A, Leitao MM, Eisenhauer EL, DiSilvestro P, Van Le L, Pearl ML, Burke JJ,Salani R, Richardson DL, Michael HE, Kindelberger DW, Birrer MJ. Mol Cancer Ther. 2020 Aug 26. doi: 10.1158/1535-7163.MCT-20-0276. Online ahead of print.PMID: 32847980
  • Meeting report from the 2020 Annual (virtual) Meeting of the American Society of Clinical Oncology.Salani R, Liu JF. Gynecol Oncol. 2020 Oct;159(1):13-16. doi: 10.1016/j.ygyno.2020.06.502. Epub 2020 Aug 5.PMID: 32771275 Free PMC article.No abstract available.
  • Practice patterns in post-treatment surveillance in patients with primary epithelial ovarian cancer.DeMari J, Vetter MH, Chandra S, Hays JL,Salani R. Int J Gynecol Cancer. 2020 Aug 5:ijgc-2020-001522. doi: 10.1136/ijgc-2020-001522. Online ahead of print.PMID: 32759182
  • Resident Self-Entrustment and Expectations of Autonomy: OB > GYN?Smith BQ, Woelfel I,Salani R, Harzman A, Chen X. J Surg Educ. 2020 Aug 1:S1931-7204(20)30253-1. doi: 10.1016/j.jsurg.2020.07.019. Online ahead of print.PMID: 32753260
  • Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants.Barnes DR, Rookus MA, McGuffog L…Salani R…et al.Genet Med. 2020 Oct;22(10):1653-1666. doi: 10.1038/s41436-020-0862-x. Epub 2020 Jul 15.PMID: 32665703 
  • Residents' method for gaining operative autonomy.Woelfel I, Smith BQ, Strosberg D, Villarreal M, Harzman A,Salani R, Cochran A, Chen XP. Am J Surg. 2020 Oct;220(4):893-898. doi: 10.1016/j.amjsurg.2020.03.022. Epub 2020 Mar 29.PMID: 32248947
  • Sridhar A, Zhang S, Woodson R,Kwan L. Non-pharmacological anxiety reduction with immersive virtual reality for first-trimester dilation and curettage: a pilot study (Accepted for publication October 2020) 
  • Sridhar A, Friedman S, Myung-Shin K, Troung W, Elias S. Impact of perceived contraceptive policy changes on long acting reversible contraceptive dispensing trends. (Accepted for publication October 2020)
  • Lakshminrusimha S,Sridhar A, Guerra AAH, Higgins RD, Saade G. Perinatal COVID-19 Infection Prevention: Infographics for Patients and Providers. published online ahead of print, 2020 Jul 19]. Am J Perinatol. 2020;10.1055/s-0040-1714387. doi:10.1055/s-0040-1714387