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About Nelson's Syndrome
Nelson's syndrome is a rare disorder that occurs in some patients with Cushing's disease patients as a result of removing both adrenal glands. In Nelson's syndrome, the pituitary tumor continues to grow and release the hormone ACTH.
This invasive tumor enlarges, often causing visual loss, pituitary failure and headaches. One key characteristic of Nelson's disease is dark skin pigmentation, resulting from the skin pigment cells responding to the release of ACTH.
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