Published on March 27, 2023
"Certain genes are differentially expressed, meaning they have different activity, in people with pulmonary arterial hypertension (PAH) whose right side of the heart fails to work as it should, a study found.
Researchers believe that those genes, generally involved in regulating the electrical properties of the heart’s muscle cells, called cardiac myocytes, could provide possible targets to treat right heart failure.
“We hope to identify potential drug therapies that target [heart right side] arrhythmias,” or irregularities, the team wrote.
The study, 'Electrical Remodeling in Right Ventricular Failure Due to Pulmonary Hypertension: Unraveling Novel Therapeutic Targets,' was published in the International Journal of Molecular Sciences."